79 Publications (Page 1 of 4)
2021
Direct visualization by FRET-FLIM of a putative mechanosome complex involving Src, Pyk2 and MBD2 in living MLO-Y4 cells
Day, Richard NDay, Kathleen H and Pavalko, Fredrick M
PLoS One, vol. 16, (no. 12), Dec 2021. | Journal Article
2020
PIE-FLIM Measurements of Two Different FRET-Based Biosensor Activities in the Same Living Cells
Reissaus, Christopher AReissaus, Christopher AReissaus, Christopher ADay, Kathleen HDay, Kathleen HDay, Kathleen HMirmira, Raghavendra GMirmira, Raghavendra GMirmira, Raghavendra GDunn, Kenneth WDunn, Kenneth WDunn, Kenneth WPavalko, Fredrick MPavalko, Fredrick MPavalko, Fredrick MDay, Richard NDay, Richard N and Day, Richard N
Biophysical Journal, vol. 118, (no. 8), pp. 1829, 2020-04-21. | Journal Article
2019
Expression of a Degradation‐Resistant β‐Catenin Mutant in Osteocytes Protects the Skeleton From Mechanodeprivation‐Induced Bone Wasting
Bullock, Whitney ABullock, Whitney ABullock, Whitney AHoggatt, April MHoggatt, April MHoggatt, April MHoran, Daniel JHoran, Daniel JHoran, Daniel JLewis, Karl JLewis, Karl JLewis, Karl JYokota, HirokiYokota, HirokiYokota, HirokiHann, StevenHann, StevenHann, StevenWarman, Matthew LWarman, Matthew LWarman, Matthew LSebastian, AimySebastian, AimySebastian, AimyLoots, Gabriela GLoots, Gabriela GLoots, Gabriela GPavalko, Fredrick MPavalko, Fredrick MPavalko, Fredrick MRobling, Alexander GRobling, Alexander G and Robling, Alexander G
Journal of Bone and Mineral Research, vol. 34, (no. 10), pp. 1975, October 2019. | Journal Article
 
Lrp4 Mediates Bone Homeostasis and Mechanotransduction through Interaction with Sclerostin In Vivo
Bullock, Whitney ABullock, Whitney ABullock, Whitney AHoggatt, April MHoggatt, April MHoggatt, April MHoran, Daniel JHoran, Daniel JHoran, Daniel JElmendorf, Andrew JElmendorf, Andrew JElmendorf, Andrew JSato, Amy YSato, Amy YSato, Amy YBellido, TeresitaBellido, TeresitaBellido, TeresitaLoots, Gabriela GLoots, Gabriela GLoots, Gabriela GPavalko, Fredrick MPavalko, Fredrick MPavalko, Fredrick MRobling, Alexander GRobling, Alexander G and Robling, Alexander G
iScience, vol. 20, (no. C), pp. 215, 2019-Oct-25. | Journal Article
2016
Hydroxy-Safflower Yellow A inhibits the TNFR1-Mediated Classical NF-κB Pathway by Inducing Shedding of TNFR1.
Wang, HaifangLiu, JinlianYang, YuejinCao, QingwenHuo, XuepingMa, ShuhuiHu, JunPavalko, Fredrick M and Liu, Qinshe
Phytotherapy research : PTR, vol. 30, (no. 5), pp. 790-796, May 2016. | Journal Article
2015
Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis.
Childress, PaulChildress, PaulChildress, PaulChildress, PaulChildress, PaulStayrook, Keith RStayrook, Keith RStayrook, Keith RStayrook, Keith RStayrook, Keith RAlvarez, Marta BAlvarez, Marta BAlvarez, Marta BAlvarez, Marta BAlvarez, Marta BWang, ZhipingWang, ZhipingWang, ZhipingWang, ZhipingWang, ZhipingShao, YuShao, YuShao, YuShao, YuShao, YuHernandez-Buquer, SeleneHernandez-Buquer, SeleneHernandez-Buquer, SeleneHernandez-Buquer, SeleneHernandez-Buquer, SeleneMack, Justin KMack, Justin KMack, Justin KMack, Justin KMack, Justin KGrese, Zachary RGrese, Zachary RGrese, Zachary RGrese, Zachary RGrese, Zachary RHe, YongzhengHe, YongzhengHe, YongzhengHe, YongzhengHe, YongzhengHoran, DanielHoran, DanielHoran, DanielHoran, DanielHoran, DanielPavalko, Fredrick MPavalko, Fredrick MPavalko, Fredrick MPavalko, Fredrick MPavalko, Fredrick MWarden, Stuart JWarden, Stuart JWarden, Stuart JWarden, Stuart JWarden, Stuart JRobling, Alexander GRobling, Alexander GRobling, Alexander GRobling, Alexander GRobling, Alexander GYang, Feng-ChunYang, Feng-ChunYang, Feng-ChunYang, Feng-ChunYang, Feng ChunAllen, Matthew RAllen, Matthew RAllen, Matthew RAllen, Matthew RAllen, Matthew RKrishnan, VenkateshKrishnan, VenkateshKrishnan, VenkateshKrishnan, VenkateshKrishnan, VenkateshLiu, YunlongLiu, YunlongLiu, YunlongLiu, YunlongLiu, YunlongBidwell, Joseph PBidwell, Joseph PBidwell, Joseph PBidwell, Joseph P and Bidwell, Joseph P
Molecular endocrinology (Baltimore, Md.), vol. 29, (no. 9), pp. 1269-1285, September 2015. | Journal Article
 
Signaling pathways involved in megakaryocyte-mediated proliferation of osteoblast lineage cells.
Cheng, Ying-HuaCheng, Ying-HuaCheng, Ying‐HuaStreicher, Drew AStreicher, Drew AStreicher, Drew AWaning, David LWaning, David LWaning, David LChitteti, Brahmananda RChitteti, Brahmananda RChitteti, Brahmananda RGerard‐O'Riley, RitaGerard-O'Riley, RitaGerard-O'Riley, RitaHorowitz, Mark CHorowitz, Mark CHorowitz, Mark CBidwell, Joseph PBidwell, Joseph PBidwell, Joseph PPavalko, Fredrick MPavalko, Fredrick MPavalko, Fredrick MSrour, Edward FSrour, Edward FSrour, Edward FMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DKacena, Melissa AKacena, Melissa A and Kacena, Melissa A
Journal of cellular physiology, vol. 230, (no. 3), pp. 578-586, March 2015. | Journal Article
2014
Estrogen receptor-[Beta] regulates mechanical signaling in primary osteoblasts
Castillo, Alesha BTriplett, JasonPavalko, Fredrick M and Turner, Charles H
American Journal of Physiology, vol. 306, (no. 8), Apr 15, 2014. | Journal Article
 
Estrogen receptor-β regulates mechanical signaling in primary osteoblasts.
Castillo, Alesha BTriplett, JasonPavalko, Fredrick M and Turner, Charles H
American journal of physiology. Endocrinology and metabolism, vol. 306, (no. 8), pp. E937-44, 2014/Apr/15. | Journal Article
 
Mechanical loading in osteocytes induces formation of a Src/Pyk2/MBD2 complex that suppresses anabolic gene expression.
Hum, Julia MDay, Richard NBidwell, Joseph PWang, Yingxiao and Pavalko, Fredrick M
PloS one, vol. 9, (no. 5), pp. e97942, 2014. | Journal Article
2013
Focal adhesion kinase is important for fluid shear stress‐induced mechanotransduction in osteoblasts
Young, Suzanne RLGerard‐O'Riley, RitaKim, Jae‐Beom and Pavalko, Fredrick M
Journal of Bone and Mineral Research, vol. 28, (no. 11), pp. 2431, November 2013. | Journal Article
 
Pyk2 regulates megakaryocyte-induced increases in osteoblast number and bone formation.
Cheng, Ying-HuaHooker, R ANguyen, KhanhGerard-O'Riley, RitaWaning, David LChitteti, Brahmananda RMeijome, Tomas EChua, Hui LPlett, Artur POrschell, Christie MSrour, Edward FMayo, Lindsey DPavalko, Fredrick MBruzzaniti, Angela and Kacena, Melissa
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol. 28, (no. 6), pp. 1434-45, 2013/Jun. | Journal Article
2012
Immortalization and characterization of osteoblast cell lines generated from wild-type and Nmp4-null mouse bone marrow stromal cells using murine telomerase reverse transcriptase (mTERT).
Alvarez, Marta BChildress, PaulPhilip, Binu KGerard-O'Riley, RitaHanlon, MichaelHerbert, Brittney SheaRobling, AlexanderPavalko, Fredrick M and Bidwell, Joseph
Journal of cellular physiology, vol. 227, (no. 5), pp. 1873-82, 2012/May. | Journal Article
 
Monitoring biosensor activity in living cells with fluorescence lifetime imaging microscopy.
Hum, JuliaHum, J.M.Siegel, A.P.Siegel, Amanda PPavalko, F.M.Pavalko, Fredrick MDay, Richard N and Day, R.N.
International journal of molecular sciences, vol. 13, (no. 11), pp. 14385-400, 2012. | Journal Article
 
Nmp4/CIZ closes the parathyroid hormone anabolic window.
Bidwell, JosephBidwell, JosephChildress, PaulChildress, PaulAlvarez, Marta BAlvarez, Marta BHood, MarkHood, Jr, MarkHe, YongzhengHe, YongzhengPavalko, Fredrick MPavalko, Fredrick MKacena, Melissa AKacena, Melissa AYang, Feng Chun and Yang, Feng-Chun
Critical reviews in eukaryotic gene expression, vol. 22, (no. 3), pp. 205-18, 2012. | Journal Article
2011
Blockade of TNFR1 signaling: A role of oscillatory fluid shear stress in osteoblasts.
Wang, HaifangYoung, SuzanneGerard-O'Riley, RitaHum, Julia MYang, ZhouqiBidwell, Joseph and Pavalko, Fredrick M
Journal of cellular physiology, vol. 226, (no. 4), pp. 1044-51, 2011/Apr. | Journal Article
 
Non-overlapping functions for Pyk2 and FAK in osteoblasts during fluid shear stress-induced mechanotransduction.
Young, SuzanneHum, Julia MRodenberg, EricTurner, Charles H and Pavalko, Fredrick M
PloS one, vol. 6, (no. 1), pp. e16026, 2011. | Journal Article
2010
Activation of NF-I[ordmB by fluid shear stress, but not TNF- alpha , requires focal adhesion kinase in osteoblasts
Young, SuzanneGerard-O'Riley, RitaHarrington, Maureen and Pavalko, Fredrick M
Bone, vol. 47, (no. 1), pp. 74-82, 2010. | Journal Article
 
Activation of NF-kappaB by fluid shear stress, but not TNF-alpha, requires focal adhesion kinase in osteoblasts.
Young, Suzanne R LYoung, SuzanneGerard-O'Riley, RitaGerard-O'Riley, RitaHarrington, MaureenHarrington, MaureenPavalko, Fredrick M and Pavalko, Fredrick M
Bone, vol. 47, (no. 1), pp. 74-82, 2010/Jul. | Journal Article
 
Mechanosomes carry a loaded message.
Bidwell, Joseph and Pavalko, Fredrick M
Science signaling, vol. 3, (no. 153), pp. pe51, 2010. | Journal Article
 
Nmp4/CIZ inhibits mechanically induced beta-catenin signaling activity in osteoblasts.
Yang, ZhouqiBidwell, JosephYoung, Suzanne RGerard-O'Riley, RitaWang, Haifang and Pavalko, Fredrick M
Journal of cellular physiology, vol. 223, (no. 2), pp. 435-41, 2010/May. | Journal Article
 
The Load-Bearing Mechanosome Revisited
Bidwell, JosephBidwell, JosephBidwell, JosephPavalko, FredrickPavalko, Fredrick and Pavalko, Fredrick
Clinical Reviews in Bone and Mineral Metabolism, vol. 8, (no. 4), pp. 223, 20101200. | Journal Article
 
The Load-Bearing Mechanosome Revisited.
Bidwell, Joseph P and Pavalko, Fredrick M
Clinical reviews in bone and mineral metabolism, vol. 8, (no. 4), pp. 213-223, November 11, 2010. | Journal Article
2009
Focal adhesion kinase is important for fluid shear stress-induced mechanotransduction in osteoblasts.
Young, SuzanneGerard-O'Riley, RitaKim, Jae-Beom and Pavalko, Fredrick M
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol. 24, (no. 3), pp. 411-24, 2009/Mar. | Journal Article
2007
Estrogen Receptor-Beta Regulates Mechanical Signaling in Primary Osteoblasts
Castillo, Alesha BTriplett, Jason WPavalko, Fredrick M and Turner, Charles H
Medicine & Science in Sports & Exercise, vol. 39, (no. Supplement), pp. 33, 2007-05-00. | Journal Article