24 Publications
2023
Data from Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy
 
Data from Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy
 
REV-ERB activation as a novel pharmacological approach for treating inflammatory pain.
Makhija, Sangeet⋅Griffett, Joshua D⋅Veerakanellore, Giri Babu⋅Burris, Thomas P⋅Elgendy, Bahaa and Griffett, Kristine
Frontiers in pharmacology, vol. 14, pp. 1171931, 2023. | Journal Article
 
Supplemental Figures S1-S9 from Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy
 
Supplemental Figures S1-S9 from Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy
2022
Antihyperlipidemic Activity of Gut-Restricted LXR Inverse Agonists
Griffett, Kristine⋅Hayes, Matthew⋅Bedia-Diaz, Gonzalo⋅Appourchaux, Kevin⋅Sanders, Ryan⋅Boeckman, Michael P.⋅Koelblen, Thomas⋅Zhang, Jinsong⋅Schulman, Ira G.⋅Elgendy, Bahaa and Burris, Thomas P.
ACS Chemical Biology. | Journal Article
 
Emerging Role of Nuclear Receptors for the Treatment of NAFLD and NASH
Metabolites. | Journal Article
 
Targeting Nuclear Receptors for Chronic Inflammatory Pain: A Potential Alternative
ACS Pharmacology & Translational Science. | Journal Article
2021
Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy
Kuehm, Lindsey M.⋅Khojandi, Niloufar⋅Piening, Alexander⋅Klevorn, Lauryn E.⋅Geraud, Simone C.⋅McLaughlin, Nicole R.⋅Griffett, Kristine⋅Burris, Thomas P.⋅Pyles, Kelly D.⋅Nelson, Afton M.⋅Preuss, Mary L.⋅Bockerstett, Kevin A.⋅Donlin, Maureen J.⋅McCommis, Kyle S.⋅DiPaolo, Richard J. and Teague, Ryan M.
Cancer Immunology Research, vol. 9, pp. 227–238. | Journal Article
 
Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy. Cancer Immunology Research
2020
REV-ERB agonism improves liver pathology in a mouse model of NASH
PLOS ONE. | Journal Article
 
REV-ERB Agonism Improves Liver Pathology in a Mouse Model of NASH. []
 
The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids
Cell Chemical Biology. | Journal Article
2019
Development of novel liver?X?receptor modulators based on a 1,2,4-triazole scaffold
Goher, S.S.⋅Griffett, K.⋅Hegazy, L.⋅Elagawany, M.⋅Arief, M.M.H.⋅Avdagic, A.⋅Banerjee, S.⋅Burris, T.P. and Elgendy, B.
Bioorganic and Medicinal Chemistry Letters, vol. 29, pp. 449-453. | Journal Article
 
Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold. Bioorg Med Chem Letters
2018
Inhibition of Hepatotoxicity by a LXR Inverse Agonist in a Model of Alcoholic Liver Disease
Sengupta, M.⋅Griffett, K.⋅Flaveny, C.A. and Burris, T.P.
ACS Pharmacology and Translational Science, vol. 1, pp. 50-60. | Journal Article
 
Inhibition of Hepatotoxicity by a LXR Inverse Agonist in a Model of Alcoholic Liver Disease. ACS Pharmacol Transl Sci.
2016
Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver disease
Griffett, Kristine and Burris, Thomas P.
Biochemical and Biophysical Research Communications, vol. 479, pp. 424–428. | Journal Article
2015
Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis
Flaveny, Colin A.⋅Griffett, Kristine⋅El-Gendy, Bahaa El-Dien M.⋅Kazantzis, Melissa⋅Sengupta, Monideepa⋅Amelio, Antonio L.⋅Chatterjee, Arindam⋅Walker, John⋅Solt, Laura A.⋅Kamenecka, Theodore M. and Burris, Thomas P.
Cancer Cell, vol. 28, pp. 42–56. | Journal Article
 
The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis
Griffett, Kristine⋅Welch, Ryan D.⋅Flaveny, Colin A.⋅Kolar, Grant R.⋅Neuschwander-Tetri, Brent A. and Burris, Thomas P.
Molecular Metabolism, vol. 4, pp. 353–357. | Journal Article
2014
Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour
Banerjee, Subhashis⋅Banerjee, Subhashis⋅Wang, Yongjun⋅Wang, Yongjun⋅Solt, Laura A⋅Solt, Laura A.⋅Griffett, Kristine⋅Griffett, Kristine⋅Kazantzis, Melissa⋅Kazantzis, Melissa⋅Amador, Ariadna⋅Amador, Ariadna⋅El-Gendy, Bahaa M.⋅El-gendy, Bahaa M⋅Huitron-resendiz, Salvador⋅Huitron-Resendiz, Salvador⋅Roberts, Amanda J⋅Roberts, Amanda J.⋅Shin, Youseung⋅Shin, Youseung⋅Kamenecka, Theodore M⋅Kamenecka, Theodore M.⋅Burris, Thomas P. and Burris, Thomas P
Nature Communications, vol. 5. | Journal Article
2013
Nuclear Receptors and Their Selective Pharmacologic Modulators
Burris, T. P.⋅Solt, L. A.⋅Wang, Y.⋅Crumbley, C.⋅Banerjee, S.⋅Griffett, K.⋅Lundasen, T.⋅Hughes, T. and Kojetin, D. J.
Pharmacological Reviews, vol. 65, pp. 710–778. | Journal Article
 
The mammalian clock and chronopharmacology
Griffett, Kristine and Burris, Thomas P.
Bioorganic & Medicinal Chemistry Letters, vol. 23, pp. 1929–1934. | Journal Article
2012
A Liver-Selective LXR Inverse Agonist That Suppresses Hepatic Steatosis
Griffett, Kristine⋅Solt, Laura A.⋅El-Gendy, Bahaa El-Dien M.⋅Kamenecka, Theodore M. and Burris, Thomas P.
ACS Chemical Biology, vol. 8, pp. 559–567. | Journal Article