37 Publications (Page 2 of 2)
2020
The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids
Cell Chemical Biology. | Journal Article
2019
Development of novel liver?X?receptor modulators based on a 1,2,4-triazole scaffold
Goher, S.S.Griffett, K.Hegazy, L.Elagawany, M.Arief, M.M.H.Avdagic, A.Banerjee, S.Burris, T.P. and Elgendy, B.
Bioorganic and Medicinal Chemistry Letters, vol. 29, pp. 449-453. | Journal Article
 
Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold. Bioorg Med Chem Letters
2018
Inhibition of Hepatotoxicity by a LXR Inverse Agonist in a Model of Alcoholic Liver Disease
Sengupta, M.Griffett, K.Flaveny, C.A. and Burris, T.P.
ACS Pharmacology and Translational Science, vol. 1, pp. 50-60. | Journal Article
 
Inhibition of Hepatotoxicity by a LXR Inverse Agonist in a Model of Alcoholic Liver Disease. ACS Pharmacol Transl Sci.
2016
Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver disease
Griffett, Kristine and Burris, Thomas P.
Biochemical and Biophysical Research Communications, vol. 479, pp. 424–428. | Journal Article
2015
Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis
Flaveny, Colin A.Griffett, KristineEl-Gendy, Bahaa El-Dien M.Kazantzis, MelissaSengupta, MonideepaAmelio, Antonio L.Chatterjee, ArindamWalker, JohnSolt, Laura A.Kamenecka, Theodore M. and Burris, Thomas P.
Cancer Cell, vol. 28, pp. 42–56. | Journal Article
 
The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis
Griffett, KristineWelch, Ryan D.Flaveny, Colin A.Kolar, Grant R.Neuschwander-Tetri, Brent A. and Burris, Thomas P.
Molecular Metabolism, vol. 4, pp. 353–357. | Journal Article
2014
Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour
Banerjee, SubhashisBanerjee, SubhashisWang, YongjunWang, YongjunSolt, Laura ASolt, Laura A.Griffett, KristineGriffett, KristineKazantzis, MelissaKazantzis, MelissaAmador, AriadnaAmador, AriadnaEl-Gendy, Bahaa M.El-gendy, Bahaa MHuitron-resendiz, SalvadorHuitron-Resendiz, SalvadorRoberts, Amanda JRoberts, Amanda J.Shin, YouseungShin, YouseungKamenecka, Theodore MKamenecka, Theodore M.Burris, Thomas P. and Burris, Thomas P
Nature Communications, vol. 5. | Journal Article
2013
Nuclear Receptors and Their Selective Pharmacologic Modulators
Burris, T. P.Solt, L. A.Wang, Y.Crumbley, C.Banerjee, S.Griffett, K.Lundasen, T.Hughes, T. and Kojetin, D. J.
Pharmacological Reviews, vol. 65, pp. 710–778. | Journal Article
 
The mammalian clock and chronopharmacology
Griffett, Kristine and Burris, Thomas P.
Bioorganic & Medicinal Chemistry Letters, vol. 23, pp. 1929–1934. | Journal Article
2012
A Liver-Selective LXR Inverse Agonist That Suppresses Hepatic Steatosis
Griffett, KristineSolt, Laura A.El-Gendy, Bahaa El-Dien M.Kamenecka, Theodore M. and Burris, Thomas P.
ACS Chemical Biology, vol. 8, pp. 559–567. | Journal Article