37 Publications (Page 2 of 2)
2020
The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids
Cell Chemical Biology. | Journal Article
2019
Development of novel liver?X?receptor modulators based on a 1,2,4-triazole scaffoldGoher, S.S.⋅Griffett, K.⋅Hegazy, L.⋅Elagawany, M.⋅Arief, M.M.H.⋅Avdagic, A.⋅Banerjee, S.⋅Burris, T.P. and Elgendy, B.Bioorganic and Medicinal Chemistry Letters, vol. 29, pp. 449-453.
| Journal Article
Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold. Bioorg Med Chem Letters
2018
Inhibition of Hepatotoxicity by a LXR Inverse Agonist in a Model of Alcoholic Liver DiseaseSengupta, M.⋅Griffett, K.⋅Flaveny, C.A. and Burris, T.P.ACS Pharmacology and Translational Science, vol. 1, pp. 50-60.
| Journal Article
Inhibition of Hepatotoxicity by a LXR Inverse Agonist in a Model of Alcoholic Liver Disease. ACS Pharmacol Transl Sci.
2016
Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver diseaseGriffett, Kristine and Burris, Thomas P.Biochemical and Biophysical Research Communications, vol. 479, pp. 424–428.
| Journal Article
2015
Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and LipogenesisFlaveny, Colin A.⋅Griffett, Kristine⋅El-Gendy, Bahaa El-Dien M.⋅Kazantzis, Melissa⋅Sengupta, Monideepa⋅Amelio, Antonio L.⋅Chatterjee, Arindam⋅Walker, John⋅Solt, Laura A.⋅Kamenecka, Theodore M. and Burris, Thomas P.Cancer Cell, vol. 28, pp. 42–56.
| Journal Article
The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitisGriffett, Kristine⋅Welch, Ryan D.⋅Flaveny, Colin A.⋅Kolar, Grant R.⋅Neuschwander-Tetri, Brent A. and Burris, Thomas P.Molecular Metabolism, vol. 4, pp. 353–357.
| Journal Article
2014
Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviourBanerjee, Subhashis⋅Banerjee, Subhashis⋅Wang, Yongjun⋅Wang, Yongjun⋅Solt, Laura A⋅Solt, Laura A.⋅Griffett, Kristine⋅Griffett, Kristine⋅Kazantzis, Melissa⋅Kazantzis, Melissa⋅Amador, Ariadna⋅Amador, Ariadna⋅El-Gendy, Bahaa M.⋅El-gendy, Bahaa M⋅Huitron-resendiz, Salvador⋅Huitron-Resendiz, Salvador⋅Roberts, Amanda J⋅Roberts, Amanda J.⋅Shin, Youseung⋅Shin, Youseung⋅Kamenecka, Theodore M⋅Kamenecka, Theodore M.⋅Burris, Thomas P. and Burris, Thomas PNature Communications, vol. 5.
| Journal Article
2013
Nuclear Receptors and Their Selective Pharmacologic ModulatorsBurris, T. P.⋅Solt, L. A.⋅Wang, Y.⋅Crumbley, C.⋅Banerjee, S.⋅Griffett, K.⋅Lundasen, T.⋅Hughes, T. and Kojetin, D. J.Pharmacological Reviews, vol. 65, pp. 710–778.
| Journal Article
The mammalian clock and chronopharmacologyGriffett, Kristine and Burris, Thomas P.Bioorganic & Medicinal Chemistry Letters, vol. 23, pp. 1929–1934.
| Journal Article
2012
A Liver-Selective LXR Inverse Agonist That Suppresses Hepatic SteatosisGriffett, Kristine⋅Solt, Laura A.⋅El-Gendy, Bahaa El-Dien M.⋅Kamenecka, Theodore M. and Burris, Thomas P.ACS Chemical Biology, vol. 8, pp. 559–567.
| Journal Article