45 Publications (Page 2 of 2)
2022
Antihyperlipidemic Activity of Gut-Restricted LXR Inverse Agonists
Griffett, Kristine⋅Hayes, Matthew⋅Bedia-Diaz, Gonzalo⋅Appourchaux, Kevin⋅Sanders, Ryan⋅Boeckman, Michael P.⋅Koelblen, Thomas⋅Zhang, Jinsong⋅Schulman, Ira G.⋅Elgendy, Bahaa and Burris, Thomas P.
ACS Chemical Biology. | Journal Article
 
Emerging Role of Nuclear Receptors for the Treatment of NAFLD and NASH
Metabolites. | Journal Article
 
Targeting Nuclear Receptors for Chronic Inflammatory Pain: A Potential Alternative
ACS Pharmacology & Translational Science. | Journal Article
2021
Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy
Kuehm, Lindsey M.⋅Khojandi, Niloufar⋅Piening, Alexander⋅Klevorn, Lauryn E.⋅Geraud, Simone C.⋅McLaughlin, Nicole R.⋅Griffett, Kristine⋅Burris, Thomas P.⋅Pyles, Kelly D.⋅Nelson, Afton M.⋅Preuss, Mary L.⋅Bockerstett, Kevin A.⋅Donlin, Maureen J.⋅McCommis, Kyle S.⋅DiPaolo, Richard J. and Teague, Ryan M.
Cancer Immunology Research, vol. 9, pp. 227–238. | Journal Article
 
Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy. Cancer Immunology Research
2020
REV-ERB agonism improves liver pathology in a mouse model of NASH
PLOS ONE. | Journal Article
 
REV-ERB Agonism Improves Liver Pathology in a Mouse Model of NASH. []
 
The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids
Cell Chemical Biology. | Journal Article
2019
Development of novel liver?X?receptor modulators based on a 1,2,4-triazole scaffold
Goher, S.S.⋅SS, Goher⋅Griffett, K.⋅K, Griffett⋅Hegazy, L.⋅L, Hegazy⋅M, Elagawany⋅Elagawany, M.⋅MMH, Arief⋅Arief, M.M.H.⋅A, Avdagic⋅Avdagic, A.⋅Banerjee, S.⋅S, Banerjee⋅Burris, T.P.⋅TP, Burris⋅Elgendy, B. and B, Elgendy
Bioorganic and Medicinal Chemistry Letters, vol. 29, pp. 449-453. | Journal Article
 
Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold. Bioorg Med Chem Letters
2018
Inhibition of Hepatotoxicity by a LXR Inverse Agonist in a Model of Alcoholic Liver Disease
Sengupta, M.⋅Griffett, K.⋅Flaveny, C.A. and Burris, T.P.
ACS Pharmacology and Translational Science, vol. 1, pp. 50-60. | Journal Article
 
Inhibition of Hepatotoxicity by a LXR Inverse Agonist in a Model of Alcoholic Liver Disease. ACS Pharmacol Transl Sci.
2016
Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver disease
Griffett, Kristine⋅K, Griffett⋅TP, Burris and Burris, Thomas P.
Biochemical and Biophysical Research Communications, vol. 479, pp. 424–428. | Journal Article
2015
Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis
Flaveny, Colin A.⋅CA, Flaveny⋅Griffett, Kristine⋅K, Griffett⋅El-Gendy, Bahaa El-Dien M.⋅Bel-D, El-Gendy⋅M, Kazantzis⋅Kazantzis, Melissa⋅Sengupta, Monideepa⋅AL, Amelio⋅Amelio, Antonio L.⋅Chatterjee, Arindam⋅A, Chatterjee⋅Walker, John⋅J, Walker⋅LA, Solt⋅Solt, Laura A.⋅Kamenecka, Theodore M.⋅TM, Kamenecka⋅TP, Burris and Burris, Thomas P.
Cancer Cell, vol. 28, pp. 42–56. | Journal Article
 
The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis
Griffett, Kristine⋅K, Griffett⋅Welch, Ryan D.⋅RD, Welch⋅CA, Flaveny⋅Flaveny, Colin A.⋅Kolar, Grant R.⋅GR, Kolar⋅Neuschwander-Tetri, Brent A.⋅BA, Neuschwander-Tetri⋅TP, Burris and Burris, Thomas P.
Molecular Metabolism, vol. 4, pp. 353–357. | Journal Article
2014
Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour
Banerjee, Subhashis⋅S, Banerjee⋅Banerjee, Subhashis⋅Y, Wang⋅Wang, Yongjun⋅Wang, Yongjun⋅Solt, Laura A.⋅Solt, Laura A⋅LA, Solt⋅Griffett, Kristine⋅K, Griffett⋅Griffett, Kristine⋅Kazantzis, Melissa⋅M, Kazantzis⋅Kazantzis, Melissa⋅Amador, Ariadna⋅A, Amador⋅Amador, Ariadna⋅El-Gendy, Bahaa M.⋅BM, El-Gendy⋅El-gendy, Bahaa M⋅Huitron-Resendiz, Salvador⋅Huitron-resendiz, Salvador⋅Roberts, Amanda J⋅AJ, Roberts⋅Roberts, Amanda J.⋅Shin, Youseung⋅Shin, Youseung⋅Kamenecka, Theodore M⋅Kamenecka, Theodore M.⋅TM, Kamenecka⋅Burris, Thomas P⋅TP, Burris and Burris, Thomas P.
Nature Communications, vol. 5. | Journal Article
2013
Nuclear Receptors and Their Selective Pharmacologic Modulators
Burris, T. P.⋅TP, Burris⋅Solt, L. A.⋅LA, Solt⋅Wang, Y.⋅Y, Wang⋅Crumbley, C.⋅C, Crumbley⋅S, Banerjee⋅Banerjee, S.⋅K, Griffett⋅Griffett, K.⋅Lundasen, T.⋅T, Lundasen⋅Hughes, T.⋅DJ, Kojetin and Kojetin, D. J.
Pharmacological Reviews, vol. 65, pp. 710–778. | Journal Article
 
The mammalian clock and chronopharmacology
Griffett, Kristine⋅K, Griffett⋅TP, Burris and Burris, Thomas P.
Bioorganic & Medicinal Chemistry Letters, vol. 23, pp. 1929–1934. | Journal Article
2012
A Liver-Selective LXR Inverse Agonist That Suppresses Hepatic Steatosis
Griffett, Kristine⋅K, Griffett⋅Solt, Laura A.⋅LA, Solt⋅El-Gendy, Bahaa El-Dien M.⋅Bel-D, El-Gendy⋅TM, Kamenecka⋅Kamenecka, Theodore M.⋅Burris, Thomas P. and TP, Burris
ACS Chemical Biology, vol. 8, pp. 559–567. | Journal Article
n.d.no date or unknown
Therapeutic Targeting of the LXR Pathway for Improving Myelin Integrity in Neurodegeneration