15 Publications
2023
A pentasaccharide for monitoring pharmacodynamic response to gene therapy in GM1 gangliosidosis
Kell, PamelaSidhu, RohiniQian, MingxingMishra, SonaliNicoli, Elena-RalucaD'Souza, PrecillaTifft, Cynthia JGross, Amanda LGray-Edwards, Heather LMartin, Douglas RSena- Esteves, MiguelDietzen, Dennis JSingh, ManmilanLuo, JingqinSchaffer, Jean EOry, Daniel S and Jiang, Xuntian
EBioMedicine, vol. 92, pp. 104627, Jun 1, 2023. | Journal Article
 
Life-limiting peripheral organ dysfunction in feline Sandhoff disease emerges after effective CNS gene therapy
Johnson, Aime KMcCurdy, Victoria JGray-Edwards, Heather LMaguire, Anne SCochran, J NGross, Amanda LSkinner, Haleigh ERandle, Ashley NShirley, Jamie LBrunson, Brandon LBradbury, Allison MLeroy, Stanley GHwang, MisakoRockwell, Hannah ECox, Nancy RBaker, Henry JSeyfried, Thomas NSena-Esteves, Miguel and Martin, Douglas R
Annals of neurology, Aug 1, 2023. | Journal Article
 
Rabies: who should care?
Baker, Henry JMartin, Douglas RGross, Amanda LChamorro, Manuel FNaskou, Maria CJohnson, Aime KBrock, Kenny VVan Kampen, Kent R and Willoughby, Rodney E
Journal of the American Veterinary Medical Association, vol. 261, (no. 4), pp. 592-596, Apr 1, 2023. | Journal Article
2022
AAVrh10 vector corrects pathology in animal models of GM1 gangliosidosis and achieves widespread distribution in the CNS of nonhuman primates
Hocquemiller, MichaëlGiersch, LauraMei, XinGross, Amanda L.Randle, Ashley N.Gray-Edwards, Heather L.Hudson, Judith A.Todeasa, SophiaStoica, LoreleiMartin, Douglas R.Sena-Esteves, MiguelAiach, Karen and Laufer, Ralph
Molecular therapy. Methods & clinical development, vol. 27, pp. 281-292, Dec 8, 2022. | Journal Article
 
Intravenous delivery of adeno-associated viral gene therapy in feline GM1 gangliosidosis
Gross, Amanda LGray-Edwards, Heather LBebout, Cassie NTa, Nathan LNielsen, KaylyBrunson, Brandon LLopez Mercado, Kalajan ROsterhoudt, Devin EBatista, Ana RMaitland, StacySeyfried, Thomas NSena-Esteves, Miguel and Martin, Douglas R
Brain (London, England : 1878), vol. 145, (no. 2), pp. 655-669, Apr 18, 2022. | Journal Article
 
Whole-Genome Shotgun Metagenomic Sequencing Reveals Distinct Gut Microbiome Signatures of Obese Cats
Ma, XiaoleiBrinker, EmilyGraff, Emily CCao, WenqiGross, Amanda LJohnson, Aime KZhang, ChaoMartin, Douglas R and Wang, Xu
Microbiology spectrum, vol. 10, (no. 3), pp. e0083722, Jun 1, 2022. | Journal Article
2021
Natural history of Tay-Sachs disease in sheep
Story, BrettTaghian, TolooGallagher, JillianKoehler, JeyTaylor, AmandaRandle, AshleyNielsen, KaylyGross, AmandaMaguire, AnnieCarl, SaraJohnson, SiaunaFernau, DeborahDiffie, EliseCuddon, PaulCorado, CarlyChandra, SundeepSena-Esteves, MiguelKolodny, EdwinJiang, XuntianMartin, Douglas and Gray-Edwards, Heather
Molecular genetics and metabolism, vol. 134, (no. 1-2), pp. 164-174, Sep 1, 2021. | Journal Article
2020
7T MRI Predicts Amelioration of Neurodegeneration in the Brain after AAV Gene Therapy
Gray-Edwards, Heather LMaguire, Anne SSalibi, NouhaEllis, Lauren EVoss, Taylor LDiffie, Elise BKoehler, JeyRandle, Ashley NTaylor, Amanda RBrunson, Brandon LDenney, Thomas SBeyers, Ronald JGentry, Atoska SGross, Amanda LBatista, Ana RSena-Esteves, Miguel and Martin, Douglas R
Molecular Therapy. Methods & Clinical Development, vol. 17, pp. 258-270, Jun 12, 2020. | Journal Article
 
Cardiovascular manifestations of feline Sandhoff disease after intravenous AAV gene therapy
Gross, Amanda LEllis, LaurenGarrett, CourtneyMartin, Douglas R and Wang, Raymond
Molecular genetics and metabolism, vol. 129, (no. 2), pp. S68-S69, Feb 2020. | Journal Article
2017
AAV Mediated Gene Delivery Attenuates Neuroinflammation in Feline Sandhoff Disease
Bradbury, Allison MPeterson, Tiffany AGross, Amanda LWells, Stephen ZMcCurdy, Victoria JWolfe, Karen GDennis, John CBrunson, Brandon LGray-Edwards, HeatherRandle, Ashley NJohnson, Aime KMorrison, Edward ECox, Nancy RBaker, Henry JSena-Esteves, Miguel and Martin, Douglas R
Neuroscience, vol. 340, pp. 117-125, Jan 6, 2017. | Journal Article
 
Polyethylene glycol-b-poly(lactic acid) polymersomes as vehicles for enzyme replacement therapy
Kelly, Jessica MGross, Amanda LMartin, Douglas R and Byrne, Mark E
Nanomedicine (London, England), vol. 12, (no. 23), pp. 2591-2606, Dec 1, 2017. | Journal Article
2016
605. Cerebrospinal Fluid for Delivery of AAV Gene Therapy in GM1 Gangliosidosis
Gross, Amanda LGray-Edwards, HeatherMurdock, BryanTaylor, AmandaBrunson, BrandonRandle, Ashley NStocia, LoreleiTodessa, SophiaLata, JaclynSena-Esteves, Miguel and Martin, Douglas R
Molecular therapy, vol. 24, pp. S240, May 2016. | Journal Article
 
Promiscuous tumor targeting phage proteins
Gross, Amanda LGillespie, James W and Petrenko, Valery A
Protein engineering, design and selection, vol. 29, (no. 3), pp. 93-103, Mar 1, 2016. | Journal Article
2015
Combinatorial synthesis and screening of cancer cell-specific nanomedicines targeted via phage fusion proteins
Gillespie, James WGross, Amanda LPuzyrev, Anatoliy TBedi, Deepa and Petrenko, Valery A
Frontiers in microbiology, vol. 6, pp. 628, Jun 23, 2015. | Journal Article
2011
Thiazolidinediones/PPARγ agonists and fatty acid synthase inhibitors as an experimental combination therapy for prostate cancer
MANSOUR, MahmoudMansour, MahmoudSCHWARTZ, DeanSchwartz, D. DABDEL-MAGEED, Asim BJudd, Robert LJUDD, RobertAkingbemi, Benson TBraden, Tim DAKINGBEMI, BensonBRADEN, TimMorrison, Edward EDennis, JohnMORRISON, EdwardBartol, Frank FDENNIS, JohnHazi, AmandaBARTOL, FrankNapier, IndiaHAZI, AmandaNAPIER, India and Abdel-Mageed, Asim B
International journal of oncology, vol. 38, (no. 2), pp. 537-546, Feb 1, 2011. | Journal Article