Subject Area(s): Comparative Genomics in Animal Health
Research Interests
- Comparative and functional genomics of allelic imbalance
- Genomics and metagenomics on host-microbial interactions
- Assorted topics in evolutionary genomics
Keywords: Agricultural Genomics; Detection Dogs; Parasitoids; Marsupials; Allelic imbalance
Our lab is focused on the health and disease in animals to improve companion animal heath, enhance livestock and aquaculture production, health and welfare, through the advancement of veterinary genomics and biotechnology.
The Wang laboratory's primary research area is multi-omics analysis of health, performance, production, welfare and disease in companion and farm animals, with emphasis in both fundamental sciences to veterinary/agricultural applications. We use next generation sequencing technologies and comparative/functional genomic approaches to investigate animal genome, transcriptome, DNA methylome and microbiome.
One research interest is genetic and epigenetic regulation of gene expression in vertebrates and insects. The main focus is allele-specific expression (ASE), allele-specific DNA methylation (ASM) and allele-specific histone modifications
Another research interest is the DNA methylation evolution, sex-biased gene expression, host-microbe interaction, mitochondrial-nuclear genome interaction, telomeric repeat and satellite repeat evolution using the model of parasitoid jewel wasps.
Current Projects
- Genomics Imprinting
- X Inactivation (XCI)
Topics:
- Agricultural Genomics and Metagenomics
- Detection dogs and behavioral genomics
- Veterinary Genomics and Animal Health
- Repeat evolution in animal genomes
- Sex determination, sex-biased expression, and hermaphroditism
- Allelic imbalance - genomics imprinting
- Allelic imbalance - X chromosome inactivation
- Epigenetics and gene expression regulation
- Parasitoids and Wolbachia genomics and epigenomics
- Population genetics, genomics & evolution
Skills and Expertise
- Genomics
- Genotyping
- Genetics
- Molecular Biology
- Next Generation Sequencing
- Bioinformatics and Computational Biology
- Gene Regulation
- Gene Expression
- Bioinformatics
- PCR
