16 Publications
2011
Tyrosine kinase inhibitors are potent acute pulmonary vasodilators in rats.
Abe, Kohtaro⋅Toba, Michie⋅Alzoubi, Abdallah⋅Koubsky, Karel⋅Ito, Masako⋅Ota, Hiroki⋅Gairhe, Salina⋅Gerthoffer, William T⋅Fagan, Karen A⋅Mc Murtry, Ivan and Oka, Masahiko
American journal of respiratory cell and molecular biology, vol. 45, (no. 4), pp. 804-8, 2011/Oct. | Journal Article
2010
Rho kinase-mediated vasoconstriction in pulmonary hypertension.
Mc Murtry, Ivan⋅Abe, Kohtaro⋅Ota, Hiroki⋅Fagan, Karen A and Oka, Masahiko
Advances in experimental medicine and biology, vol. 661, pp. 299-308, 2010. | Journal Article
2009
Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia.
Dempsey, Edward C⋅Wick, Marilee J⋅Karoor, Vijaya⋅Barr, Erica J⋅Tallman, Dustin W⋅Wehling, Carol A⋅Walchak, Sandra J⋅Laudi, Sven⋅Le, Mysan⋅Oka, Masahiko⋅Majka, Susan⋅Cool, Carlyne D⋅Fagan, Karen A⋅Klemm, Dwight J⋅Hersh, Louis B⋅Gerard, Norma P⋅Gerard, Craig and Miller, York E
The American journal of pathology, vol. 174, (no. 3), pp. 782-96, 2009/Mar. | Journal Article
2008
Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosterone
Homma, Noriyuki⋅Nagaoka, Tetsutaro⋅Karoor, Vijaya⋅Imamura, Masatoshi⋅Taraseviciene Stewart, Laimute⋅Walker, Lori A⋅Fagan, Karen A⋅Mc Murtry, Ivan and Oka, Masahiko
American Journal of Physiology, vol. 295, (no. 1), Jul 2008. | Journal Article
 
Rho kinase-mediated vasoconstriction in rat models of pulmonary hypertension.
Oka, Masahiko⋅Homma, Noriyuki and Mc Murtry, Ivan
Methods in enzymology, vol. 439, pp. 191-204, 2008. | Journal Article
 
Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension.
Oka, Masahiko⋅Fagan, Karen A⋅Jones, P L and Mc Murtry, Ivan
British journal of pharmacology, vol. 155, (no. 4), pp. 444-54, 2008/Oct. | Journal Article
2007
Dehydroepiandrosterone upregulates soluble guanylate cyclase and inhibits hypoxic pulmonary hypertension.
Oka, Masahiko⋅Karoor, Vijaya⋅Homma, Noriyuki⋅Nagaoka, Tetsutaro⋅Sakao, Eiko⋅Golembeski, Scott M⋅Limbird, Jennifer⋅Imamura, Masatoshi⋅Gebb, Sarah A⋅Fagan, Karen A and Mc Murtry, Ivan
Cardiovascular research, vol. 74, (no. 3), pp. 377-87, 2007/Jun/1. | Journal Article
 
Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats.
Oka, Masahiko⋅Homma, Noriyuki⋅Taraseviciene Stewart, Laimute⋅Morris, Kenneth G⋅Kraskauskas, Donatas⋅Burns, Nana⋅Voelkel, Norbert F and Mc Murtry, Ivan
Circulation research, vol. 100, (no. 6), pp. 923-9, 2007/Mar/30. | Journal Article
2006
Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat.
Nagaoka, Tetsutaro⋅Gebb, Sarah A⋅Karoor, Vijaya⋅Homma, Noriyuki⋅Morris, Kenneth G⋅Mc Murtry, Ivan and Oka, Masahiko
Journal of applied physiology (Bethesda, Md. : 1985), vol. 100, (no. 3), pp. 996-1002, 2006/Mar. | Journal Article
 
Role of pentose phosphate pathway-derived NADPH in hypoxic pulmonary vasoconstriction.
Gupte, Sachin A⋅Okada, Takao⋅Mc Murtry, Ivan and Oka, Masahiko
Pulmonary pharmacology & therapeutics, vol. 19, (no. 4), pp. 303-9, 2006. | Journal Article
2005
Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice
Ling, Xiaofeng⋅Cota-Gomez, Adela⋅Flores, Natalia C⋅Hernandez-Saavedra, Daniel⋅Mc Cord, Joe M⋅Marecki, John C⋅Haskins, Kathryn⋅McDuffie, Marcia⋅Powers, Katherine⋅Kench, Jennifer⋅Oka, Masahiko⋅Mc Murtry, Ivan and Flores, Sonia
Free Radical Biology and Medicine, vol. 39, (no. 8), pp. 1089-1098, 2005. | Journal Article
 
Hypoxic pulmonary hypertension is prevented in rats with common bile duct ligation.
Imamura, Masatoshi⋅Luo, Bao⋅Limbird, Jennifer⋅Vitello, Andrea⋅Oka, Masahiko⋅Ivy, D. D⋅Mc Murtry, Ivan⋅Garat, Chrystelle V⋅Fallon, Michael B and Carter, Ethan P
Journal of applied physiology (Bethesda, Md. : 1985), vol. 98, (no. 2), pp. 739-47, 2005/Feb. | Journal Article
 
Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension.
Nagaoka, Tetsutaro⋅Nagaoka, Tetsutaro⋅Fagan, Karen A⋅Fagan, Karen A⋅Gebb, Sarah A⋅Gebb, Sarah A⋅Morris, Kenneth G⋅Morris, Kenneth G⋅Suzuki, Tsutomu⋅Shimokawa, Hiroaki⋅Mc Murtry, Ivan and Oka, Masahiko
American journal of respiratory and critical care medicine, vol. 171, (no. 5), pp. 494-9, 2005/Mar/1. | Journal Article
2004
Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase.
Fagan, Karen A⋅Oka, Masahiko⋅Bauer, Natalie⋅Gebb, Sarah A⋅Ivy, D D⋅Morris, Kenneth G and Mc Murtry, Ivan
American journal of physiology. Lung cellular and molecular physiology. , vol. 287, (no. 4), pp. L656-64, 2004/Oct. | Journal Article
1993
BQ123, an ETA receptor antagonist, attenuates endothelin-1-induced vasoconstriction in rat pulmonary circulation.
Bonvallet, S T⋅Oka, Masahiko⋅Yano, M⋅Zamora, Martin R⋅Mc Murtry, Ivan and Stelzner, T J
Journal of cardiovascular pharmacology, vol. 22, (no. 1), pp. 39-43, 1993/Jul. | Journal Article
 
NIP-121 is more effective than nifedipine in acutely reversing chronic pulmonary hypertension.
Oka, Masahiko⋅Morris, K G and Mc Murtry, Ivan
Journal of applied physiology (Bethesda, Md. : 1985), vol. 75, (no. 3), pp. 1075-80, 1993/Sep. | Journal Article