23 Publications
2011
Mitochondrial DNA integrity may be a determinant of endothelial barrier properties in oxidant-challenged rat lungs
Chouteau, Joshua MObiako, BonifaceGorodnya, Olena MPastukh, ViktorRuchko, Mykhaylo VWright, Anthony JWilson, Glenn L and Gillespie, Mark
American Journal of Physiology, vol. 301, (no. 6), Dec 2011. | Journal Article
 
Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences.
Pastukh, ViktorZhang, LiRuchko, Mykhaylo VGorodnya, OlenaBardwell, Gina CTuder, Rubin M and Gillespie, Mark
International journal of chronic obstructive pulmonary disease, vol. 6, pp. 209-17, 2011. | Journal Article
 
The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells
Ruchko, Mykhaylo VGorodnya, Olena MZuleta, AndresPastukh, Viktor and Gillespie, Mark
Free Radical Biology and Medicine, vol. 50, (no. 9), pp. 1107-1113, 2011. | Journal Article
2010
Controlled DNA damage and repair in hypoxic signaling
Gillespie, MarkPastukh, Viktor and Ruchko, Mykhaylo V
Respiratory Physiology & Neurobiology, vol. 174, (no. 3), pp. 244-251, 2010. | Journal Article
 
Effect of hypernatremia on injury caused by energy deficiency: role of T-type Ca2+ channel.
Pastukh, ViktorChen, HairuWu, SongweiJong, Chian JAlexeyev, Mikhail F and Schaffer, Stephen W
American journal of physiology. Cell physiology, vol. 299, (no. 2), pp. C289-97, 2010/Aug. | Journal Article
2009
Effect of taurine on protein kinase C isoforms: role in taurine's actions?
Ito, TakashiPastukh, ViktorSolodushko, ViktoriyaAzuma, Junichi and Schaffer, Stephen W
Advances in experimental medicine and biology, vol. 643, pp. 3-11, 2009. | Journal Article
 
Hypoxia-induced oxidative base modifications in the VEGF hypoxia-response element are associated with transcriptionally active nucleosomes
Ruchko, Mykhaylo VGorodnya, Olena MPastukh, ViktorSwiger, Brad MMiddleton, Natavia SWilson, Glenn L and Gillespie, Mark
Free Radical Biology and Medicine, vol. 46, (no. 3), pp. 352-359, 2009. | Journal Article
 
Oxidative DNA modifications in hypoxic signaling.
Gillespie, MarkPastukh, Viktor and Ruchko, Mykhaylo V
Annals of the New York Academy of Sciences, vol. 1177, pp. 140-50, 2009/Oct. | Journal Article
 
Oxidative DNA Modifications in Hypoxic Signaling
Gillespie, MarkPastukh, Viktor and Ruchko, Mykhaylo V
Annals of the New York Academy of Sciences, vol. 1177, (no. 1), pp. 140-150, 2009. | Journal Article
2008
Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis
Ricci, CraigRicci, CraigRicci, CraigPastukh, ViktorPastukh, ViktorPastukh, ViktorLeonard, JoshLeonard, Joshua NLeonard, JoshTurrens, JulioTurrens, JulioTurrens, JulioWilson, GlennWilson, Glenn LWilson, GlennSchaffer, DavidSchaffer, DavidSchaffer, David VSchaffer, Stephen WSchaffer, Stephen W and Schaffer, Stephen W
American Journal of Physiology, vol. 294, (no. 2), Feb 2008. | Journal Article
 
Selective elimination of mutant mitochondrial genomes as therapeutic strategy for the treatment of NARP and MILS syndromes
Alexeyev, MVenediktova, NPastukh, VShokolenko, IBonilla, G and Wilson, G
Gene Therapy, vol. 15, (no. 7), pp. 516-23, Apr 2008. | Journal Article
 
Selective elimination of mutant mitochondrial genomes as therapeutic strategy for the treatment of NARP and MILS syndromes
Alexeyev, Mikhail FVenediktova, NPastukh, ViktorShokolenko, IBonilla, G and Wilson, Glenn L
Gene Therapy, vol. 15, (no. 7), pp. 516-23, Apr 2008. | Journal Article
2007
Insulin withdrawal induces apoptosis via a free radical-mediated mechanism.
Ricci, CraigPastukh, ViktorMozaffari, Mahmood S and Schaffer, Stephen W
Canadian journal of physiology and pharmacology, vol. 85, (no. 3-4), pp. 455-64, 2007 Mar-Apr. | Journal Article
 
Insulin withdrawal induces apoptosis via a free radical-mediated mechanism1
Ricci, CraigPastukh, ViktorMozaffari, Mahmood S and Schaffer, Stephen W
Canadian Journal of Physiology and Pharmacology, vol. 85, (no. 3/4), pp. 455-64, Mar/Apr 2007. | Journal Article
 
Sequence-specific oxidative base modifications in hypoxia-inducible genes
Pastukh, ViktorRuchko, Mykhaylo VGorodnya, OlenaWilson, Glenn L and Gillespie, Mark
Free Radical Biology and Medicine, vol. 43, (no. 12), pp. 1616-1626, 2007. | Journal Article
2005
Contribution of the PI 3-kinase/Akt survival pathway toward osmotic preconditioning.
Pastukh, ViktorRicci, CraigSolodushko, ViktoriyaMozaffari, Mahmood S and Schaffer, Stephen W
Molecular and cellular biochemistry, vol. 269, (no. 1-2), pp. 59-67, 2005/Jan. | Journal Article
 
Involvement of the mitochondrial permeability transition pore in angiotensin II-mediated apoptosis.
Ricci, CraigPastukh, Viktor and Schaffer, Stephen W
Experimental and clinical cardiology, vol. 10, (no. 3), pp. 160-4, 2005. | Journal Article
 
Reversal of hyperglycemic preconditioning by angiotensin II: role of calcium transport
Pastukh, ViktorWu, SongweiRicci, CraigMozaffari, Mahmood S and Schaffer, Stephen W
American Journal of Physiology: Heart and Circulatory Physiology, vol. 288, (no. 4), pp. H1965-H1975, 2005. | Journal Article
 
Reversal of hyperglycemic preconditioning by angiotensin II: role of calcium transport
Pastukh, ViktorWu, SongweiRicci, CraigMozaffari, Mahmood S and Schaffer, Stephen W
American Journal of Physiology, vol. 57, (no. 4), pp. H1965-H1975, Apr 2005. | Journal Article
2003
Apoptotic cascade initiated by angiotensin II in neonatal cardiomyocytes: role of DNA damage.
Grishko, ValentinaPastukh, ViktorSolodushko, ViktoriyaGillespie, MarkAzuma, Junichi and Schaffer, Stephen W
American journal of physiology. Heart and circulatory physiology, vol. 285, (no. 6), pp. H2364-72, 2003/Dec. | Journal Article
 
Apoptotic cascade initiated by angiotensin II in neonatal cardiomyocytes: Role of DNA damage
Grishko, ValentinaPastukh, ViktorSolodushko, ViktoriyaGillespie, Mark and al, et
American Journal of Physiology, vol. 54, (no. 6), pp. H2364-H2372, Dec 2003. | Journal Article
 
Possible cause of taurine-deficient cardiomyopathy: potentiation of angiotensin II action.
Schaffer, Stephen WSolodushko, ViktoriyaPastukh, ViktorRicci, Craig and Azuma, Junichi
Journal of cardiovascular pharmacology, vol. 41, (no. 5), pp. 751-9, 2003/May. | Journal Article
2002
Effect of ischemia, calcium depletion and repletion, acidosis and hypoxia on cellular taurine content.
Schaffer, Stephen WPastukh, ViktorSolodushko, VKramer, Jay H and Azuma, J
Amino acids, vol. 23, (no. 4), pp. 395-400, 2002. | Journal Article