Viktor M. Pastukh Instructor

Expertise:

• Transcriptional control in lung cells

Research Interests:

• Role of mitochondrial DNA damage in endothelial cell apoptosis caused by oxidative stress, role of vascular endothelial growth factor (VEGF) in lung vessels remodeling
• Apoptosis in lung cells
• Role glucose, fatty acid and insulin in mitochondrial DNA damage in cardiomyocytes caused by oxidative stress
• Insulin-linked regulators of the MPT pore
• Role of the T-type Ca2+ channel in osmotic preconditioning
• Cell signaling systems (Ca2+, PI 3-kinase/Akt pathway, protein kinase C) after hypoxia and in osmotic preconditioning
• Apoptosis in cardiomyocytes
• Role of angiotensin II in cardiomyopathy
• Cell signaling systems (Ca2+, cyclic nucleotides, inositol system, protein kinases) after irradiation in low doses
• Role of 5-lipoxygenase activity in lymphocytes of rat spleen after irradiation