182 Publications (Page 1 of 8)
2013
Dehydroepiandrosterone restores right ventricular structure and function in rats with severe pulmonary arterial hypertensionAlzoubi, Abdallah⋅Toba, Michie⋅Abe, Kohtaro⋅O'Neill, Kealan D⋅Rocic, Petra⋅Fagan, Karen A⋅McMurtry, Ivan F and Oka, MasahikoAmerican Journal of Physiology, vol. 304, (no. 12), Jun 15, 2013.
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2011
Tyrosine kinase inhibitors are potent acute pulmonary vasodilators in rats.Abe, Kohtaro⋅Toba, Michie⋅Alzoubi, Abdallah⋅Koubsky, Karel⋅Ito, Masako⋅Ota, Hiroki⋅Gairhe, Salina⋅Gerthoffer, William T⋅Fagan, Karen A⋅McMurtry, Ivan and Oka, MasahikoAmerican journal of respiratory cell and molecular biology, vol. 45, (no. 4), pp. 804-8, 2011/Oct.
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2010
Rho kinase-mediated vasoconstriction in pulmonary hypertension.McMurtry, Ivan⋅Abe, Kohtaro⋅Ota, Hiroki⋅Fagan, Karen A and Oka, MasahikoAdvances in experimental medicine and biology, vol. 661, pp. 299-308, 2010.
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Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report.Erzurum, Serpil C⋅Polgar, Peter⋅Rounds, Sharon⋅Stevens, Troy⋅Aldred, Micheala⋅Aliotta, Jason⋅Archer, Stephen L⋅Asosingh, Kewal⋅Balaban, Robert⋅Bauer, Natalie⋅Bhattacharya, Jahar⋅Bogaard, Harm⋅Choudhary, Gaurav⋅Dorn, Gerald W⋅Dweik, Raed A⋅Fagan, Karen A⋅Fallon, Michael⋅Finkel, Toren⋅Geraci, Mark W⋅Gladwin, Mark T⋅Hassoun, Paul M⋅Humbert, Marc⋅Kaminski, Naftali⋅Kawut, Steven⋅Loscalzo, Joseph⋅Mc Donald, Donald M⋅McMurtry, Ivan⋅Newman, John H⋅Nicolls, Mark R⋅Rabinovitch, Marlene⋅Shizuru, Judy⋅Oka, Masahiko⋅Polgar, Peter⋅Rodman, David⋅Schumacker, Paul T⋅Stenmark, Kurt⋅Tuder, Rubin M⋅Voelkel, Norbert F⋅Sullivan, Eugene⋅Weinshilboum, Richard⋅Yoder, Mervin C⋅Zhao, Yingming⋅Gail, Dorothy and Moore, Timothy MAmerican journal of respiratory and critical care medicine, vol. 182, (no. 12), pp. 1554-62, 2010/Dec/15.
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2009
Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure.Stenmark, Kurt R⋅Meyrick, Barbara O⋅Galie, Nazzareno⋅Mooi, Wolter J and McMurtry, Ivan FAmerican journal of physiology. Lung cellular and molecular physiology, vol. 297, (no. 6), pp. L1013-32, 2009/Dec.
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Cellular and molecular basis of pulmonary arterial hypertension.Morrell, Nicholas⋅Morrell, Nicholas W⋅Adnot, Serge⋅Adnot, Serge⋅Archer, Stephen L⋅Archer, Stephen L⋅Dupuis, Jocelyn⋅Dupuis, Jocelyn⋅Lloyd Jones, Peter⋅Jones, Peter L⋅MacLean, Margaret R⋅Mac Lean, Mandy R⋅McMurtry, Ivan⋅McMurtry, Ivan F⋅Stenmark, Kurt R⋅Stenmark, Kurt R⋅Thistlethwaite, Patricia A⋅Thistlethwaite, Patricia A⋅Weissmann, Norbert⋅Weissmann, Norbert⋅Yuan, Jason X⋅Yuan, Jason X⋅Weir, E K and Weir, E KJournal of the American College of Cardiology, vol. 54, (no. 1 Suppl), pp. S20-31, 2009/Jun/30.
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Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem
Ward, Jeremy P and McMurtry, Ivan
Current Opinion in Pharmacology, vol. 9, (no. 3), pp. 287-296, 2009. | Journal Article
2008
Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosteroneHomma, Noriyuki⋅Nagaoka, Tetsutaro⋅Karoor, Vijaya⋅Imamura, Masatoshi⋅Taraseviciene Stewart, Laimute⋅Walker, Lori A⋅Fagan, Karen A⋅McMurtry, Ivan and Oka, MasahikoAmerican Journal of Physiology, vol. 295, (no. 1), Jul 2008.
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Rho kinase-mediated vasoconstriction in rat models of pulmonary hypertension.Oka, Masahiko⋅Homma, Noriyuki and McMurtry, IvanMethods in enzymology, vol. 439, pp. 191-204, 2008.
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Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension.Oka, Masahiko⋅Fagan, Karen A⋅Jones, P L and McMurtry, IvanBritish journal of pharmacology, vol. 155, (no. 4), pp. 444-54, 2008/Oct.
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2007
Counterpoint: Chronic hypoxia-induced pulmonary hypertension does not lead to loss of pulmonary vasculature.
McLoughlin, P and McMurtry, Ivan
Journal of applied physiology (Bethesda, Md. : 1985), vol. 103, (no. 4), pp. 1451-3; discussion 1453-4, 2007/Oct. | Journal Article
Dehydroepiandrosterone upregulates soluble guanylate cyclase and inhibits hypoxic pulmonary hypertension.Oka, Masahiko⋅Karoor, Vijaya⋅Homma, Noriyuki⋅Nagaoka, Tetsutaro⋅Sakao, Eiko⋅Golembeski, Scott M⋅Limbird, Jennifer⋅Imamura, Masatoshi⋅Gebb, Sarah A⋅Fagan, Karen A and McMurtry, IvanCardiovascular research, vol. 74, (no. 3), pp. 377-87, 2007/Jun/1.
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Endothelin-1 and serotonin are involved in activation of RhoA/Rho kinase signaling in the chronically hypoxic hypertensive rat pulmonary circulation.
Homma, Noriyuki⋅Nagaoka, Tetsutaro⋅Morio, Yoshiteru⋅Ota, Hiroki⋅Gebb, Sarah A⋅Karoor, Vijaya⋅McMurtry, Ivan and Oka, Masahiko
Journal of cardiovascular pharmacology, vol. 50, (no. 6), pp. 697-702, 2007/Dec. | Journal Article
Last Word on Point:Counterpoint "Chronic hypoxia-induced pulmonary hypertension does/does not lead to loss of pulmonary vasculature".McLoughlin, Paul and McMurtry, Ivan(pp. 1456). October 2007
Last Word on Point:Counterpoint "Chronic hypoxia-induced pulmonary hypertension does/does not lead to loss of pulmonary vasculature".McLoughlin, Paul⋅Rabinovitch, Marlene⋅Chesler, Naomi⋅McMurtry, Ivan and Molthen, Robert CJournal of applied physiology (Bethesda, Md. : 1985), vol. 103, (no. 4), pp. 1456, 2007/Oct.
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Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats.Oka, Masahiko⋅Homma, Noriyuki⋅Taraseviciene Stewart, Laimute⋅Morris, Kenneth G⋅Kraskauskas, Donatas⋅Burns, Nana⋅Voelkel, Norbert F and McMurtry, IvanCirculation research, vol. 100, (no. 6), pp. 923-9, 2007/Mar/30.
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Rodent models of PAH: are we there yet?Bauer, Natalie R⋅Bauer, Natalie⋅Moore, Timothy M⋅Moore, Timothy M⋅McMurtry, Ivan and McMurtry, Ivan FAmerican journal of physiology. Lung cellular and molecular physiology, vol. 293, (no. 3), pp. L580-2, 2007/Sep.
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Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling.Crossno, Joseph T⋅Garat, Chrystelle V⋅Reusch, Jane E⋅Morris, Kenneth G⋅Dempsey, Edward C⋅McMurtry, Ivan⋅Stenmark, Kurt R and Klemm, Dwight JAmerican journal of physiology. Lung cellular and molecular physiology, vol. 292, (no. 4), pp. L885-97, 2007/Apr.
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2006
Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat.Nagaoka, Tetsutaro⋅Gebb, Sarah A⋅Karoor, Vijaya⋅Homma, Noriyuki⋅Morris, Kenneth G⋅McMurtry, Ivan and Oka, MasahikoJournal of applied physiology (Bethesda, Md. : 1985), vol. 100, (no. 3), pp. 996-1002, 2006/Mar.
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Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells.Garat, Chrystelle V⋅Fankell, Dana⋅Erickson, Paul F⋅Reusch, Jane E⋅Bauer, Natalie⋅McMurtry, Ivan and Klemm, Dwight JMolecular and cellular biology, vol. 26, (no. 13), pp. 4934-48, 2006/Jul.
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Role of pentose phosphate pathway-derived NADPH in hypoxic pulmonary vasoconstriction.Gupte, Sachin A⋅Okada, Takao⋅McMurtry, Ivan and Oka, MasahikoPulmonary pharmacology & therapeutics, vol. 19, (no. 4), pp. 303-9, 2006.
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2005
Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic miceLing, Xiaofeng⋅Cota-Gomez, Adela⋅Flores, Natalia C⋅Hernandez-Saavedra, Daniel⋅Mc Cord, Joe M⋅Marecki, John C⋅Haskins, Kathryn⋅McDuffie, Marcia⋅Powers, Katherine⋅Kench, Jennifer⋅Oka, Masahiko⋅McMurtry, Ivan and Flores, SoniaFree Radical Biology and Medicine, vol. 39, (no. 8), pp. 1089-1098, 2005.
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Hypoxic pulmonary hypertension is prevented in rats with common bile duct ligation.Imamura, Masatoshi⋅Luo, Bao⋅Limbird, Jennifer⋅Vitello, Andrea⋅Oka, Masahiko⋅Ivy, D. D⋅McMurtry, Ivan⋅Garat, Chrystelle V⋅Fallon, Michael B and Carter, Ethan PJournal of applied physiology (Bethesda, Md. : 1985), vol. 98, (no. 2), pp. 739-47, 2005/Feb.
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Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension.Nagaoka, Tetsutaro⋅Nagaoka, Tetsutaro⋅Fagan, Karen A⋅Fagan, Karen A⋅Gebb, Sarah A⋅Gebb, Sarah A⋅Morris, Kenneth G⋅Morris, Kenneth G⋅Suzuki, Tsutomu⋅Shimokawa, Hiroaki⋅McMurtry, Ivan and Oka, MasahikoAmerican journal of respiratory and critical care medicine, vol. 171, (no. 5), pp. 494-9, 2005/Mar/1.
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Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: a time for reappraisal?Stenmark, Kurt R and McMurtry, IvanCirculation research, vol. 97, (no. 2), pp. 95-8, 2005/Jul/22.
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