182 Publications (Page 1 of 8)
2013
Dehydroepiandrosterone restores right ventricular structure and function in rats with severe pulmonary arterial hypertension
Alzoubi, AbdallahToba, MichieAbe, KohtaroO'Neill, Kealan DRocic, PetraFagan, Karen AMcMurtry, Ivan F and Oka, Masahiko
American Journal of Physiology, vol. 304, (no. 12), Jun 15, 2013. | Journal Article
2011
Tyrosine kinase inhibitors are potent acute pulmonary vasodilators in rats.
Abe, KohtaroToba, MichieAlzoubi, AbdallahKoubsky, KarelIto, MasakoOta, HirokiGairhe, SalinaGerthoffer, William TFagan, Karen AMcMurtry, Ivan and Oka, Masahiko
American journal of respiratory cell and molecular biology, vol. 45, (no. 4), pp. 804-8, 2011/Oct. | Journal Article
2010
Rho kinase-mediated vasoconstriction in pulmonary hypertension.
McMurtry, IvanAbe, KohtaroOta, HirokiFagan, Karen A and Oka, Masahiko
Advances in experimental medicine and biology, vol. 661, pp. 299-308, 2010. | Journal Article
 
Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report.
Erzurum, Serpil CPolgar, PeterRounds, SharonStevens, TroyAldred, MichealaAliotta, JasonArcher, Stephen LAsosingh, KewalBalaban, RobertBauer, NatalieBhattacharya, JaharBogaard, HarmChoudhary, GauravDorn, Gerald WDweik, Raed AFagan, Karen AFallon, MichaelFinkel, TorenGeraci, Mark WGladwin, Mark THassoun, Paul MHumbert, MarcKaminski, NaftaliKawut, StevenLoscalzo, JosephMc Donald, Donald MMcMurtry, IvanNewman, John HNicolls, Mark RRabinovitch, MarleneShizuru, JudyOka, MasahikoPolgar, PeterRodman, DavidSchumacker, Paul TStenmark, KurtTuder, Rubin MVoelkel, Norbert FSullivan, EugeneWeinshilboum, RichardYoder, Mervin CZhao, YingmingGail, Dorothy and Moore, Timothy M
American journal of respiratory and critical care medicine, vol. 182, (no. 12), pp. 1554-62, 2010/Dec/15. | Journal Article
2009
Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure.
Stenmark, Kurt RMeyrick, Barbara OGalie, NazzarenoMooi, Wolter J and McMurtry, Ivan F
American journal of physiology. Lung cellular and molecular physiology, vol. 297, (no. 6), pp. L1013-32, 2009/Dec. | Journal Article
 
Cellular and molecular basis of pulmonary arterial hypertension.
Morrell, NicholasMorrell, Nicholas WAdnot, SergeAdnot, SergeArcher, Stephen LArcher, Stephen LDupuis, JocelynDupuis, JocelynLloyd Jones, PeterJones, Peter LMacLean, Margaret RMac Lean, Mandy RMcMurtry, IvanMcMurtry, Ivan FStenmark, Kurt RStenmark, Kurt RThistlethwaite, Patricia AThistlethwaite, Patricia AWeissmann, NorbertWeissmann, NorbertYuan, Jason XYuan, Jason XWeir, E K and Weir, E K
Journal of the American College of Cardiology, vol. 54, (no. 1 Suppl), pp. S20-31, 2009/Jun/30. | Journal Article
 
Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem
Ward, Jeremy P and McMurtry, Ivan
Current Opinion in Pharmacology, vol. 9, (no. 3), pp. 287-296, 2009. | Journal Article
2008
Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosterone
Homma, NoriyukiNagaoka, TetsutaroKaroor, VijayaImamura, MasatoshiTaraseviciene Stewart, LaimuteWalker, Lori AFagan, Karen AMcMurtry, Ivan and Oka, Masahiko
American Journal of Physiology, vol. 295, (no. 1), Jul 2008. | Journal Article
 
Rho kinase-mediated vasoconstriction in rat models of pulmonary hypertension.
Oka, MasahikoHomma, Noriyuki and McMurtry, Ivan
Methods in enzymology, vol. 439, pp. 191-204, 2008. | Journal Article
 
Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension.
Oka, MasahikoFagan, Karen AJones, P L and McMurtry, Ivan
British journal of pharmacology, vol. 155, (no. 4), pp. 444-54, 2008/Oct. | Journal Article
2007
Counterpoint: Chronic hypoxia-induced pulmonary hypertension does not lead to loss of pulmonary vasculature.
McLoughlin, P and McMurtry, Ivan
Journal of applied physiology (Bethesda, Md. : 1985), vol. 103, (no. 4), pp. 1451-3; discussion 1453-4, 2007/Oct. | Journal Article
 
Dehydroepiandrosterone upregulates soluble guanylate cyclase and inhibits hypoxic pulmonary hypertension.
Oka, MasahikoKaroor, VijayaHomma, NoriyukiNagaoka, TetsutaroSakao, EikoGolembeski, Scott MLimbird, JenniferImamura, MasatoshiGebb, Sarah AFagan, Karen A and McMurtry, Ivan
Cardiovascular research, vol. 74, (no. 3), pp. 377-87, 2007/Jun/1. | Journal Article
 
Endothelin-1 and serotonin are involved in activation of RhoA/Rho kinase signaling in the chronically hypoxic hypertensive rat pulmonary circulation.
Homma, NoriyukiNagaoka, TetsutaroMorio, YoshiteruOta, HirokiGebb, Sarah AKaroor, VijayaMcMurtry, Ivan and Oka, Masahiko
Journal of cardiovascular pharmacology, vol. 50, (no. 6), pp. 697-702, 2007/Dec. | Journal Article
 
Last Word on Point:Counterpoint "Chronic hypoxia-induced pulmonary hypertension does/does not lead to loss of pulmonary vasculature".
McLoughlin, Paul and McMurtry, Ivan
(pp. 1456). October 2007
 
Last Word on Point:Counterpoint "Chronic hypoxia-induced pulmonary hypertension does/does not lead to loss of pulmonary vasculature".
McLoughlin, PaulRabinovitch, MarleneChesler, NaomiMcMurtry, Ivan and Molthen, Robert C
Journal of applied physiology (Bethesda, Md. : 1985), vol. 103, (no. 4), pp. 1456, 2007/Oct. | Journal Article
 
Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats.
Oka, MasahikoHomma, NoriyukiTaraseviciene Stewart, LaimuteMorris, Kenneth GKraskauskas, DonatasBurns, NanaVoelkel, Norbert F and McMurtry, Ivan
Circulation research, vol. 100, (no. 6), pp. 923-9, 2007/Mar/30. | Journal Article
 
Rodent models of PAH: are we there yet?
Bauer, Natalie RBauer, NatalieMoore, Timothy MMoore, Timothy MMcMurtry, Ivan and McMurtry, Ivan F
American journal of physiology. Lung cellular and molecular physiology, vol. 293, (no. 3), pp. L580-2, 2007/Sep. | Journal Article
 
Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling.
Crossno, Joseph TGarat, Chrystelle VReusch, Jane EMorris, Kenneth GDempsey, Edward CMcMurtry, IvanStenmark, Kurt R and Klemm, Dwight J
American journal of physiology. Lung cellular and molecular physiology, vol. 292, (no. 4), pp. L885-97, 2007/Apr. | Journal Article
2006
Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat.
Nagaoka, TetsutaroGebb, Sarah AKaroor, VijayaHomma, NoriyukiMorris, Kenneth GMcMurtry, Ivan and Oka, Masahiko
Journal of applied physiology (Bethesda, Md. : 1985), vol. 100, (no. 3), pp. 996-1002, 2006/Mar. | Journal Article
 
Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells.
Garat, Chrystelle VFankell, DanaErickson, Paul FReusch, Jane EBauer, NatalieMcMurtry, Ivan and Klemm, Dwight J
Molecular and cellular biology, vol. 26, (no. 13), pp. 4934-48, 2006/Jul. | Journal Article
 
Role of pentose phosphate pathway-derived NADPH in hypoxic pulmonary vasoconstriction.
Gupte, Sachin AOkada, TakaoMcMurtry, Ivan and Oka, Masahiko
Pulmonary pharmacology & therapeutics, vol. 19, (no. 4), pp. 303-9, 2006. | Journal Article
2005
Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice
Ling, XiaofengCota-Gomez, AdelaFlores, Natalia CHernandez-Saavedra, DanielMc Cord, Joe MMarecki, John CHaskins, KathrynMcDuffie, MarciaPowers, KatherineKench, JenniferOka, MasahikoMcMurtry, Ivan and Flores, Sonia
Free Radical Biology and Medicine, vol. 39, (no. 8), pp. 1089-1098, 2005. | Journal Article
 
Hypoxic pulmonary hypertension is prevented in rats with common bile duct ligation.
Imamura, MasatoshiLuo, BaoLimbird, JenniferVitello, AndreaOka, MasahikoIvy, D. DMcMurtry, IvanGarat, Chrystelle VFallon, Michael B and Carter, Ethan P
Journal of applied physiology (Bethesda, Md. : 1985), vol. 98, (no. 2), pp. 739-47, 2005/Feb. | Journal Article
 
Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension.
Nagaoka, TetsutaroNagaoka, TetsutaroFagan, Karen AFagan, Karen AGebb, Sarah AGebb, Sarah AMorris, Kenneth GMorris, Kenneth GSuzuki, TsutomuShimokawa, HiroakiMcMurtry, Ivan and Oka, Masahiko
American journal of respiratory and critical care medicine, vol. 171, (no. 5), pp. 494-9, 2005/Mar/1. | Journal Article
 
Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: a time for reappraisal?
Stenmark, Kurt R and McMurtry, Ivan
Circulation research, vol. 97, (no. 2), pp. 95-8, 2005/Jul/22. | Journal Article