19 Publications
2021
High resolution crystal structure of the Borreliella burgdorferi PlzA protein in complex with c-di-GMP: new insights into the interaction of c-di-GMP with the novel xPilZ domain.
Singh, Avinash⋅Izac, Jerilyn R⋅Schuler, Edward J A⋅Patel, Dhara T⋅Davies, Christopher and Marconi, Richard T
Pathogens and disease, June 12, 2021. | Journal Article
 
Molecular Features of Cephalosporins Important for Activity against Antimicrobial-Resistant Neisseria gonorrhoeae.
Turner, Jonathan M⋅Connolly, Kristie L⋅Aberman, Kate E⋅Fonseca, Joseph C⋅Singh, Avinash⋅Jerse, Ann E⋅Nicholas, Robert A and Davies, Christopher
ACS infectious diseases, February 3, 2021. | Journal Article
2020
Development and optimization of OspC chimeritope vaccinogens for Lyme disease.
Izac, Jerilyn R⋅O'Bier, Nathaniel S⋅Oliver, Lee D⋅Camire, Andrew C⋅Earnhart, Christopher G⋅LeBlanc Rhodes, DeLacy V⋅Young, Brandon F⋅Parnham, Stuart R⋅Davies, Christopher and Marconi, Richard T
Vaccine, vol. 38, (no. 8), pp. 1915-1924, February 18, 2020. | Journal Article
 
Mutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics.
Singh, Avinash⋅Turner, Jonathan M⋅Tomberg, Joshua⋅Fedarovich, Alena⋅Unemo, Magnus⋅Nicholas, Robert A and Davies, Christopher
The Journal of biological chemistry, vol. 295, (no. 21), pp. 7529-7543, May 22, 2020. | Journal Article
2019
1H, 13C, and 15N resonance assignments of N-acetylmuramyl-L-alanine amidase (AmiC) N-terminal domain (NTD) from Neisseria gonorrhoeae.
Young, Brandon F⋅Roth, Braden M and Davies, Christopher
Biomolecular NMR assignments, vol. 13, (no. 1), pp. 63-66, April 2019. | Journal Article
2018
Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme.
Lv, Zongyang⋅Lv, Zongyang⋅Yuan, Lingmin⋅Yuan, Lingmin⋅Atkison, James H⋅Atkison, James H⋅Williams, Katelyn M⋅Williams, Katelyn M⋅Vega, Ramir⋅Vega, Ramir⋅Sessions, E Hampton⋅Sessions, E Hampton⋅Divlianska, Daniela B⋅Divlianska, Daniela B⋅Davies, Christopher⋅Davies, Christopher⋅Chen, Yuan⋅Chen, Yuan⋅Olsen, Shaun K and Olsen, Shaun K
Nature communications, vol. 9, (no. 1), pp. 5145, December 4, 2018. | Journal Article
 
The Structure of the Biofilm-controlling Response Regulator BfmR from Acinetobacter baumannii Reveals Details of Its DNA-binding Mechanism.
Draughn, G Logan⋅Milton, Morgan E⋅Feldmann, Erik A⋅Bobay, Benjamin G⋅Roth, Braden M⋅Olson, Andrew L⋅Thompson, Richele J⋅Actis, Luis A⋅Davies, Christopher and Cavanagh, John
Journal of molecular biology, vol. 430, (no. 6), pp. 806-821, March 16, 2018. | Journal Article
2017
CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response
Hong, Feng⋅Liu, Bei⋅Wu, Bill X⋅Morreall, Jordan⋅Roth, Brady⋅Davies, Christopher⋅Sun, Shaoli⋅Diehl, J A and Li, Zihai
Nature Structural & Molecular Biology, vol. 24, (no. 10), pp. 834-839, Oct 2017. | Journal Article
2012
A highly conserved interaction involving the middle residue of the SXN active-site motif is crucial for function of class B penicillin-binding proteins: mutational and computational analysis of PBP 2 from N. gonorrhoeae.
Tomberg, Joshua⋅Tomberg, Joshua⋅Temple, Brenda⋅Temple, Brenda⋅Fedarovich, Alena⋅Fedarovich, Alena⋅Davies, Christopher⋅Davies, Christopher⋅Nicholas, Robert A and Nicholas, Robert A
Biochemistry, vol. 51, (no. 13), pp. 2775-2784, April 3, 2012. | Journal Article
 
High-throughput screening for novel inhibitors of Neisseria gonorrhoeae penicillin-binding protein 2.
Fedarovich, Alena⋅Fedarovich, Alena⋅Djordjevic, Kevin A⋅Djordjevic, Kevin A⋅Swanson, Shauna M⋅Swanson, Shauna M⋅Peterson, Yuri K⋅Peterson, Yuri K⋅Nicholas, Robert A⋅Nicholas, Robert A⋅Davies, Christopher and Davies, Christopher
PloS one, vol. 7, (no. 9), pp. e44918, 2012. | Journal Article
2010
Human tissue transglutaminase is inhibited by pharmacologic and chemical acetylation.
Lai, Thung S⋅Lai, Thung Shen⋅Davies, Christopher⋅Davies, Christopher⋅Greenberg, Charles S and Greenberg, Charles S
Protein science : a publication of the Protein Society, vol. 19, (no. 2), pp. 229-235, February 2010. | Journal Article
2009
Crystal structures of penicillin-binding protein 2 from penicillin-susceptible and -resistant strains of Neisseria gonorrhoeae reveal an unexpectedly subtle mechanism for antibiotic resistance.
Powell, Ailsa J⋅Powell, Ailsa J⋅Tomberg, Joshua⋅Tomberg, Joshua⋅Deacon, Ashley M⋅Deacon, Ashley M⋅Nicholas, Robert A⋅Nicholas, Robert A⋅Davies, Christopher and Davies, Christopher
The Journal of biological chemistry, vol. 284, (no. 2), pp. 1202-1212, January 9, 2009. | Journal Article
 
Direct binding of glyceraldehyde 3-phosphate dehydrogenase to telomeric DNA protects telomeres against chemotherapy-induced rapid degradation.
Demarse, Neil A⋅Demarse, NA⋅Ponnusamy, Suriyan⋅Ponnusamy, S.⋅Spicer, Eleanor K⋅Spicer, Eleanor⋅Apohan, Elif⋅Apohan, E.⋅Baatz, JE⋅Baatz, John E⋅Ogretmen, Besim⋅Ogretmen, Besim⋅Davies, Christopher and Davies, Christopher
Journal of molecular biology, vol. 394, (no. 4), pp. 789-803, December 11, 2009. | Journal Article
 
Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae.
Zhao, Shuqing⋅Zhao, Shuqing⋅Duncan, Margaret⋅Duncan, Margaret⋅Tomberg, Joshua⋅Tomberg, Joshua⋅Davies, Christopher⋅Davies, Christopher⋅Unemo, Magnus⋅Unemo, Magnus⋅Nicholas, Robert A and Nicholas, Robert A
Antimicrobial agents and chemotherapy, vol. 53, (no. 9), pp. 3744-3751, September 2009. | Journal Article
2008
Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle.
Sauvage, Eric⋅Sauvage, Eric⋅Powell, AJ⋅Powell, Ailsa J⋅Heilemann, J.⋅Heilemann, Jason⋅Josephine, HR⋅Josephine, Helen R⋅Charlier, Paulette⋅Charlier, Paulette⋅Davies, Christopher⋅Davies, Christopher⋅Pratt, Rex F and Pratt, R F
Journal of molecular biology, vol. 381, (no. 2), pp. 383-393, August 29, 2008. | Journal Article
2006
Crystal structure of pi initiator protein-iteron complex of plasmid R6K: implications for initiation of plasmid DNA replication.
Swan, Michael K⋅Swan, Michael K⋅Bastia, Deepak⋅Bastia, Deepak⋅Davies, Christopher and Davies, Christopher
Proceedings of the National Academy of Sciences of the United States of America, vol. 103, (no. 49), pp. 18481-18486, December 5, 2006. | Journal Article
2004
The crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase: mechanism of hydrolysis and its interplay with the dehydrogenase domain.
Chumanevich, Alexander A⋅Chumanevich, Alexander A⋅Krupenko, Sergey A⋅Krupenko, Sergey A⋅Davies, Christopher and Davies, Christopher
The Journal of biological chemistry, vol. 279, (no. 14), pp. 14355-14364, April 2, 2004. | Journal Article
2003
Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complex.
Nicholas, Robert A⋅Nicholas, Robert A⋅Krings, Sandra⋅Krings, S.⋅Tomberg, J.⋅Tomberg, Joshua⋅Nicola, G.⋅Nicola, George⋅Davies, Christopher and Davies, Christopher
The Journal of biological chemistry, vol. 278, (no. 52), pp. 52826-52833, December 26, 2003. | Journal Article
 
Structural evidence for a hydride transfer mechanism of catalysis in phosphoglucose isomerase from Pyrococcus furiosus.
Swan, MK⋅Swan, Michael K⋅Solomons, JTG⋅Solomons, J T Graham⋅Beeson, CC⋅Beeson, Craig C⋅Hansen, T.⋅Hansen, Thomas⋅Schoenheit, P.⋅Schönheit, Peter⋅Davies, Christopher and Davies, Christopher
The Journal of biological chemistry, vol. 278, (no. 47), pp. 47261-47268, November 21, 2003. | Journal Article