19 Publications
2015
Development and Characterization of a Novel in vitro Progression Model for UVB-Induced Skin Carcinogenesis.
Tyagi, Nikhil⋅Bhardwaj, Arun⋅Srivastava, Sanjeev K⋅Arora, Sumit⋅Marimuthu, Saravanakumar⋅Deshmukh, Sachin K⋅Singh, Ajay P⋅Carter, James E and Singh, Seema
Scientific reports, vol. 5, pp. 13894, 2015. | Journal Article
 
Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications.
Khan, Mohammad Aslam⋅Srivastava, Sanjeev K⋅Bhardwaj, Arun⋅Singh, Seema⋅Arora, Sumit⋅Zubair, Haseeb⋅Carter, James E and Singh, Ajay P
Oncotarget, vol. 6, (no. 36), pp. 39140-39150, November 17, 2015. | Journal Article
 
Resistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation.
Deshmukh, Sachin K⋅Srivastava, Sanjeev K⋅Bhardwaj, Arun⋅Singh, Ajay P⋅Tyagi, Nikhil⋅Marimuthu, Saravanakumar⋅Dyess, Donna L⋅Dal Zotto, Valeria⋅Carter, James E and Singh, Seema
Oncotarget, vol. 6, (no. 13), pp. 11231-11241, May 10, 2015. | Journal Article
 
Silver nanoparticles protect human keratinocytes against UVB radiation-induced DNA damage and apoptosis: potential for prevention of skin carcinogenesis.
Arora, Sumit⋅Tyagi, Nikhil⋅Bhardwaj, Arun⋅Rusu, Lilia⋅Palanki, Rohan⋅Vig, Komal⋅Singh, Shree R⋅Singh, Ajay P⋅Palanki, Srinivas⋅Miller, Michael E⋅Carter, James E and Singh, Seema
Nanomedicine : nanotechnology, biology, and medicine, vol. 11, (no. 5), pp. 1265-1275, July 2015. | Journal Article
 
Silver nanoparticles protect human keratinocytes against UVB radiation-induced DNA damage and apoptosis: potential for prevention of skin carcinogenesis.
Arora, Sumit⋅Tyagi, Nikhil⋅Bhardwaj, Arun⋅Rusu, Lilia⋅Palanki, Rohan⋅Vig, Komal⋅Singh, Shree R⋅Singh, Ajay P⋅Palanki, Srinivas⋅Miller, Michael E⋅Carter, James E and Singh, Seema
Nanomedicine : nanotechnology, biology, and medicine, vol. 11, (no. 5), pp. 1265-1275, July 2015. | Journal Article
 
Size is an essential parameter in governing the UVB-protective efficacy of silver nanoparticles in human keratinocytes
Palanki, Rohan⋅Arora, Sumit⋅Tyagi, Nikhil⋅Rusu, Lilia⋅Singh, Ajay⋅Palanki, Srinivas⋅Carter, James and Singh, Seema
BMC Cancer, vol. 15, 2015. | Journal Article
2014
CXCL12/CXCR4 signaling counteracts docetaxel-induced microtubule stabilization via p21-activated kinase 4-dependent activation of LIM domain kinase 1.
Bhardwaj, Arun⋅Srivastava, Sanjeev K⋅Singh, Seema⋅Arora, Sumit⋅Tyagi, Nikhil⋅Andrews, Joel⋅McClellan, Steven⋅Carter, James E and Singh, Ajay P
Oncotarget, vol. 5, (no. 22), pp. 11490-11500, November 30, 2014. | Journal Article
 
MicroRNAs in pancreatic malignancy: progress and promises.
Srivastava, Sanjeev K⋅Arora, Sumit⋅Singh, Seema⋅Bhardwaj, Arun⋅Averett, Courey and Singh, Ajay P
Cancer letters, vol. 347, (no. 2), pp. 167-174, June 1, 2014. | Journal Article
 
p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway.
Tyagi, Nikhil⋅Bhardwaj, Arun⋅Singh, Ajay P⋅McClellan, Steven⋅Carter, James E and Singh, Seema
Oncotarget, vol. 5, (no. 18), pp. 8778-8789, September 30, 2014. | Journal Article
2013
Cancer "stemness"- regulating microRNAs: role, mechanisms and therapeutic potential.
Bhardwaj, Arun⋅Arora, Sumit⋅Prajapati, Vijay K⋅Singh, Seema and Singh, Ajay P
Current drug targets, vol. 14, (no. 10), pp. 1175-1184, September 2013. | Journal Article
2012
CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: implications for bidirectional tumor-stromal interactions.
Singh, Ajay P⋅Arora, Sumit⋅Bhardwaj, Arun⋅Srivastava, Sanjeev K⋅Kadakia, Madhavi P⋅Wang, Bin⋅Grizzle, William E⋅Owen, Laurie B and Singh, Seema
The Journal of biological chemistry, vol. 287, (no. 46), pp. 39115-24, 2012/Nov/9. | Journal Article
 
Modulation of CXCL-8 expression in human melanoma cells regulates tumor growth, angiogenesis, invasion, and metastasis.
Wu, Sheng⋅Singh, Seema⋅Varney, Michelle L⋅Kindle, Scott and Singh, Rakesh K
Cancer medicine, vol. 1, (no. 3), pp. 306-17, 2012/Dec. | Journal Article
 
Myb overexpression overrides androgen depletion-induced cell cycle arrest and apoptosis in prostate cancer cells, and confers aggressive malignant traits: potential role in castration resistance.
Srivastava, Sanjeev K⋅Bhardwaj, Arun⋅Singh, Seema⋅Arora, Sumit⋅McClellan, Steven⋅Grizzle, William E⋅Reed, Eddie and Singh, Ajay P
Carcinogenesis, vol. 33, (no. 6), pp. 1149-1157, June 2012. | Journal Article
2011
Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells.
Arora, Sumit⋅Bhardwaj, Arun⋅Srivastava, Sanjeev K⋅Singh, Seema⋅McClellan, Steven⋅Wang, Bin and Singh, Ajay P
PloS one, vol. 6, (no. 6), pp. e21573, 2011. | Journal Article
 
MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells.
Srivastava, Sanjeev K⋅Bhardwaj, Arun⋅Singh, Seema⋅Arora, Sumit⋅Wang, Bin⋅Grizzle, William E and Singh, Ajay P
Carcinogenesis, vol. 32, (no. 12), pp. 1832-1839, December 2011. | Journal Article
 
Modulation of protein phosphatase 2A activity alters androgen-independent growth of prostate cancer cells: therapeutic implications.
Bhardwaj, Arun⋅Singh, Seema⋅Srivastava, Sanjeev K⋅Honkanen, Richard E⋅Reed, Eddie and Singh, Ajay P
Molecular cancer therapeutics, vol. 10, (no. 5), pp. 720-731, May 2011. | Journal Article
2010
Small interfering RNA-mediated CXCR1 or CXCR2 knock-down inhibits melanoma tumor growth and invasion
Singh, Seema⋅Sadanandam, Anguraj⋅Varney, Michelle L⋅Nannuru, Kalyan C and Singh, Rakesh K
International Journal of Cancer, vol. 126, (no. 2), pp. 328-336, 2010. | Journal Article
2009
Host CXCR2-dependent regulation of melanoma growth, angiogenesis, and experimental lung metastasis.
Singh, Seema⋅Varney, Michelle and Singh, Rakesh K
Cancer research, vol. 69, (no. 2), pp. 411-5, 2009/Jan/15. | Journal Article
 
Small-molecule antagonists for CXCR2 and CXCR1 inhibit human melanoma growth by decreasing tumor cell proliferation, survival, and angiogenesis.
Singh, Seema⋅Sadanandam, Anguraj⋅Nannuru, Kalyan C⋅Varney, Michelle L⋅Mayer-Ezell, Rosemary⋅Bond, Richard and Singh, Rakesh K
Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 15, (no. 7), pp. 2380-6, 2009/Apr/1. | Journal Article