His laboratory primarily focuses on the molecular mechanisms involved in cancer progression and chemoresistance, and development of novel mechanism-based approaches for cancer therapy and prevention.
This lab focuses on the functioning of the tumor cells at the molecular level. Specifically, lab members are interested in understanding how the tumor cells communicate with its surroundings to attain a variety of malignant phenotypes and if targeting of these tumor-stromal cell interactions could be exploited for cancer prevention and therapy. Another focus is to understand the molecular dissimilarities in tumors from patients of different racial backgrounds and investigate their roles in cancer health disparities.
Research Interests:
- Molecular mechanisms involved in cancer progression and chemoresistance
- Cancer progression and metastasis
- Therapeutic resistance in cancer
- Tumor-stromal interactions
- Molecular bases of cancer health disparities
- MicroRNAs in cancer
- Molecular diagnosis, prognosis and sub-classification of cancer
- Natural products as cancer prevention and therapy agents.
