23 Publications
2020
cAMP signaling primes lung endothelial cells to activate caspase-1 during Pseudomonas aeruginosa infection.
Renema, Phoibe⋅Renema, Phoibe⋅Hardy, Kierra S.⋅Hardy, Kierra S⋅Housley, Nicole⋅Housley, Nicole⋅Dunbar, Grace⋅Dunbar, Grace⋅Annamdevula, Naga⋅Annamdevula, Naga⋅Britain, Andrea⋅Britain, Andrea⋅Spadafora, Domenico⋅Spadafora, Domenico⋅Leavesley, Silas⋅Leavesley, Silas⋅Rich, Thomas⋅Rich, Thomas⋅Audia, Jonathon P.⋅Audia, Jonathon P⋅Alvarez, Diego F and Alvarez, Diego F.
American journal of physiology. Lung cellular and molecular physiology, vol. 318, (no. 5), pp. L1074-L1083, May 1, 2020. | Journal Article
2019
Excitation-Scanning Hyperspectral Imaging Microscopy to Efficiently Discriminate Fluorescence Signals.
Deal, Joshua⋅Britain, Andrea⋅Rich, Thomas and Leavesley, Silas
Journal of visualized experiments : JoVE, (no. 150), August 22, 2019. | Journal Article
2018
Identifying molecular contributors to autofluorescence of neoplastic and normal colon sections using excitation-scanning hyperspectral imaging.
Deal, Joshua⋅Mayes, Sam⋅Browning, Craig⋅Hill, Shante⋅Rider, Paul⋅Boudreaux, Carole⋅Rich, Thomas C and Leavesley, Silas J
Journal of biomedical optics, vol. 24, (no. 2), pp. 1-11, December 2018. | Journal Article
 
Nosocomial Pneumonia Elicits an Endothelial Proteinopathy: Evidence for a Source of Neurotoxic Amyloids in Critically Ill Patients
Lin, Mike T⋅Balczon, Ron⋅Pittet, Jean-Francois⋅Wagener, Brant M⋅Moser, Stephen A⋅Morrow, K A⋅Voth, Sarah⋅Francis, C M⋅Leavesley, Silas⋅Bell, Jessica⋅Alvarez, Diego F and Stevens, Troy
Dec 15, 2018
 
Nosocomial Pneumonia Elicits an Endothelial Proteinopathy: Evidence for a Source of Neurotoxic Amyloids in Critically Ill Patients
Lin, Mike T.⋅Balczon, Ron⋅Pittet, Jean-Francois⋅Wagener, Brant M.⋅Moser, Stephen A.⋅Morrow, K. Adam⋅Voth, Sarah⋅Francis, C. Michael⋅Leavesley, Silas⋅Bell, Jessica⋅Alvarez, Diego F. and Stevens, Troy
Dec 2018
 
Nosocomial Pneumonia Elicits an Endothelial Proteinopathy: Evidence for a Source of Neurotoxic Amyloids in Critically Ill Patients.
Lin, Mike T⋅Lin, Mike T⋅Lin, Mike T⋅Lin, M.T.⋅Balczon, R.⋅Balczon, Ron⋅Balczon, Ron⋅Balczon, Ron⋅Pittet, Jean-Francois⋅Pittet, Jean-Francois⋅Pittet, J.-F.⋅Pittet, Jean-Francois⋅Wagener, Brant M⋅Wagener, B.M.⋅Wagener, Brant M⋅Wagener, Brant M⋅Moser, Stephen A⋅Moser, S.A.⋅Moser, Stephen A⋅Moser, Stephen A⋅Morrow, K Adam⋅Morrow, K Adam⋅Morrow, K Adam⋅Morrow, K.A.⋅Voth, Sarah⋅Voth, Sarah⋅Voth, Sarah⋅Voth, S.⋅Francis, C Michael⋅Francis, C Michael⋅Francis, C Michael⋅Francis, C.M.⋅Leavesley, Silas⋅Leavesley, S.⋅Leavesley, Silas⋅Leavesley, Silas⋅Bell, Jessica⋅Bell, Jessica⋅Bell, J.⋅Bell, Jessica⋅Alvarez, Diego F⋅Alvarez, D.F.⋅Alvarez, Diego F⋅Alvarez, Diego F⋅Stevens, T.⋅Stevens, Troy⋅Stevens, Troy and Stevens, Troy
American journal of respiratory and critical care medicine, vol. 198, (no. 12), pp. 1575-1578, December 15, 2018. | Journal Article
 
Spectral imaging of FRET-based sensors reveals sustained cAMP gradients in three spatial dimensions.
Annamdevula, Naga S⋅Sweat, Rachel⋅Griswold, John R⋅Trinh, Kenny⋅Hoffman, Chase⋅West, Savannah⋅Deal, Joshua⋅Britain, Andrea L⋅Jalink, Kees⋅Rich, Thomas C and Leavesley, Silas J
Cytometry. Part A : the journal of the International Society for Analytical Cytology, September 3, 2018. | Journal Article
2016
Hyperspectral imaging fluorescence excitation scanning for colon cancer detection.
Leavesley, Silas J⋅Walters, Mikayla⋅Lopez, Carmen⋅Baker, Thomas⋅Favreau, Peter F⋅Rich, Thomas C⋅Rider, Paul F and Boudreaux, Carole W
Journal of biomedical optics, vol. 21, (no. 10), pp. 104003, October 1, 2016. | Journal Article
2015
Automated image analysis of FRET signals for subcellular cAMP quantification.
Leavesley, S.J.⋅Leavesley, Silas J⋅Nakhmani, Arie⋅Nakhmani, A.⋅Gao, Y.⋅Gao, Yi⋅Rich, T.C. and Rich, Thomas C
Methods in molecular biology (Clifton, N.J.), vol. 1294, pp. 59-70, 2015. | Journal Article
 
Channel-based reporters for cAMP detection.
Rich, Thomas C⋅Xin, Wenkuan⋅Leavesley, Silas J and Taylor, Mark S
Methods in molecular biology (Clifton, N.J.), vol. 1294, pp. 71-84, 2015. | Journal Article
 
Estimating the magnitude of near-membrane PDE4 activity in living cells.
Xin, Wenkuan⋅Feinstein, Wei P⋅Britain, Andrea L⋅Ochoa, Cristhiaan D⋅Zhu, Bing⋅Richter, Wito⋅Leavesley, Silas J and Rich, Thomas C
American journal of physiology. Cell physiology, vol. 309, (no. 6), pp. C415-C424, September 15, 2015. | Journal Article
 
Modification of Fibers with Nanostructures Using Reactive Dye Chemistry.
Bunge, Meagan A⋅Bunge, M.A.⋅Neil Ruckart, K⋅Ruckart, K.N.⋅Leavesley, Silas⋅Leavesley, S.⋅Peterson, G.W.⋅Peterson, Gregory W⋅Nguyen, Nien⋅Nguyen, N.⋅West, K.N.⋅West, Kevin N⋅Grant Glover, T and Glover, T.G.
Industrial & engineering chemistry research, vol. 54, (no. 15), pp. 3821-3827, April 22, 2015. | Journal Article
2014
A device for performing automated balloon catheter inflation ischemia studies.
Leavesley, Silas J⋅Ledkins, Whitley and Rocic, Petra
PloS one, vol. 9, (no. 4), pp. e95823, 2014. | Journal Article
 
Can we decipher the information content contained within cyclic nucleotide signals?
Rich, Thomas C⋅Webb, Kristal J and Leavesley, Silas J
The Journal of general physiology, vol. 143, (no. 1), pp. 17-27, January 2014. | Journal Article
 
Excitation-scanning hyperspectral imaging microscope.
Favreau, Peter F⋅Hernandez, Clarissa⋅Heaster, Tiffany⋅Alvarez, Diego F⋅Rich, Thomas C⋅Prabhat, Prashant and Leavesley, Silas J
Journal of biomedical optics, vol. 19, (no. 4), pp. 46010, 2014/Apr/1. | Journal Article
 
FRET: signals hidden within the noise.
Leavesley, Silas J and Rich, Thomas C
Cytometry. Part A : the journal of the International Society for Analytical Cytology, vol. 85, (no. 11), pp. 918-920, November 2014. | Journal Article
 
Thin-film tunable filters for hyperspectral fluorescence microscopy.
Favreau, Peter⋅Hernandez, Clarissa⋅Lindsey, Ashley S⋅Alvarez, Diego F⋅Rich, Thomas⋅Prabhat, Prashant and Leavesley, Silas J
Journal of biomedical optics, vol. 19, (no. 1), pp. 011017, 2014/Jan. | Journal Article
2013
An approach for characterizing and comparing hyperspectral microscopy systems.
Annamdevula, Naga S⋅Sweat, Brenner⋅Favreau, Peter⋅Lindsey, Ashley S⋅Alvarez, Diego F⋅Rich, Thomas C and Leavesley, Silas J
Sensors (Basel, Switzerland), vol. 13, (no. 7), pp. 9267-93, 2013. | Journal Article
 
Assessing FRET using spectral techniques.
Leavesley, Silas J⋅Britain, Andrea L⋅Cichon, Lauren K⋅Nikolaev, Viacheslav O and Rich, Thomas C
Cytometry. Part A : the journal of the International Society for Analytical Cytology, vol. 83, (no. 10), pp. 898-912, October 2013. | Journal Article
 
Hyperspectral imaging of FRET-based cGMP probes.
Rich, Thomas C⋅Britain, Andrea L⋅Stedman, Tiffany and Leavesley, Silas J
Methods in molecular biology (Clifton, N.J.), vol. 1020, pp. 73-88, 2013. | Journal Article
 
MicroRNAs as potential clinical biomarkers: emerging approaches for their detection.
Srivastava, S K⋅Bhardwaj, A⋅Leavesley, S J⋅Grizzle, W E⋅Singh, S and Singh, A P
Biotechnic & histochemistry : official publication of the Biological Stain Commission, vol. 88, (no. 7), pp. 373-387, October 2013. | Journal Article
2012
Assessment of cellular mechanisms contributing to cAMP compartmentalization in pulmonary microvascular endothelial cells
Feinstein, Wei P⋅Zhu, Bing⋅Leavesley, Silas J⋅Sayner, Sarah L and Rich, Thomas C
American Journal of Physiology, vol. 302, (no. 6), Mar 2012. | Journal Article
 
Hyperspectral imaging microscopy for identification and quantitative analysis of fluorescently-labeled cells in highly autofluorescent tissue.
Leavesley, Silas J⋅Annamdevula, Naga⋅Boni, John⋅Stocker, Samantha⋅Grant, Kristin⋅Troyanovsky, Boris⋅Rich, Thomas C and Alvarez, Diego F
Journal of biophotonics, vol. 5, (no. 1), pp. 67-84, 2012/Jan. | Journal Article