22 Publications
2020
cAMP signaling primes lung endothelial cells to activate caspase-1 during Pseudomonas aeruginosa infection.
Renema, PhoibeRenema, PhoibeHardy, Kierra S.Hardy, Kierra SHousley, NicoleHousley, NicoleDunbar, GraceDunbar, GraceAnnamdevula, NagaAnnamdevula, NagaBritain, AndreaBritain, AndreaSpadafora, DomenicoSpadafora, DomenicoLeavesley, SilasLeavesley, SilasRich, ThomasRich, ThomasAudia, Jonathon P.Audia, Jonathon PAlvarez, Diego F and Alvarez, Diego F.
American journal of physiology. Lung cellular and molecular physiology, vol. 318, (no. 5), pp. L1074-L1083, May 1, 2020. | Journal Article
2019
Excitation-Scanning Hyperspectral Imaging Microscopy to Efficiently Discriminate Fluorescence Signals.
Deal, JoshuaBritain, AndreaRich, Thomas and Leavesley, Silas
Journal of visualized experiments : JoVE, (no. 150), August 22, 2019. | Journal Article
2018
Identifying molecular contributors to autofluorescence of neoplastic and normal colon sections using excitation-scanning hyperspectral imaging.
Deal, JoshuaMayes, SamBrowning, CraigHill, ShanteRider, PaulBoudreaux, CaroleRich, Thomas C and Leavesley, Silas J
Journal of biomedical optics, vol. 24, (no. 2), pp. 1-11, December 2018. | Journal Article
 
Nosocomial Pneumonia Elicits an Endothelial Proteinopathy: Evidence for a Source of Neurotoxic Amyloids in Critically Ill Patients
Lin, Mike TBalczon, RonPittet, Jean-FrancoisWagener, Brant MMoser, Stephen AMorrow, K AVoth, SarahFrancis, C MLeavesley, SilasBell, JessicaAlvarez, Diego F and Stevens, Troy
Dec 15, 2018
 
Nosocomial Pneumonia Elicits an Endothelial Proteinopathy: Evidence for a Source of Neurotoxic Amyloids in Critically Ill Patients.
Lin, Mike TLin, Mike TLin, Mike TBalczon, RonBalczon, RonBalczon, RonPittet, Jean-FrancoisPittet, Jean-FrancoisPittet, Jean-FrancoisWagener, Brant MWagener, Brant MWagener, Brant MMoser, Stephen AMoser, Stephen AMoser, Stephen AMorrow, K AdamMorrow, K AdamMorrow, K AdamVoth, SarahVoth, SarahVoth, SarahFrancis, C MichaelFrancis, C MichaelFrancis, C MichaelLeavesley, SilasLeavesley, SilasLeavesley, SilasBell, JessicaBell, JessicaBell, JessicaAlvarez, Diego FAlvarez, Diego FAlvarez, Diego FStevens, TroyStevens, Troy and Stevens, Troy
American journal of respiratory and critical care medicine, vol. 198, (no. 12), pp. 1575-1578, December 15, 2018. | Journal Article
 
Spectral imaging of FRET-based sensors reveals sustained cAMP gradients in three spatial dimensions.
Annamdevula, Naga SSweat, RachelGriswold, John RTrinh, KennyHoffman, ChaseWest, SavannahDeal, JoshuaBritain, Andrea LJalink, KeesRich, Thomas C and Leavesley, Silas J
Cytometry. Part A : the journal of the International Society for Analytical Cytology, September 3, 2018. | Journal Article
2016
Hyperspectral imaging fluorescence excitation scanning for colon cancer detection.
Leavesley, Silas JWalters, MikaylaLopez, CarmenBaker, ThomasFavreau, Peter FRich, Thomas CRider, Paul F and Boudreaux, Carole W
Journal of biomedical optics, vol. 21, (no. 10), pp. 104003, October 1, 2016. | Journal Article
2015
Automated image analysis of FRET signals for subcellular cAMP quantification.
Leavesley, S.J.Leavesley, Silas JNakhmani, ArieNakhmani, A.Gao, Y.Gao, YiRich, T.C. and Rich, Thomas C
Methods in molecular biology (Clifton, N.J.), vol. 1294, pp. 59-70, 2015. | Journal Article
 
Channel-based reporters for cAMP detection.
Rich, Thomas CXin, WenkuanLeavesley, Silas J and Taylor, Mark S
Methods in molecular biology (Clifton, N.J.), vol. 1294, pp. 71-84, 2015. | Journal Article
 
Estimating the magnitude of near-membrane PDE4 activity in living cells.
Xin, WenkuanFeinstein, Wei PBritain, Andrea LOchoa, Cristhiaan DZhu, BingRichter, WitoLeavesley, Silas J and Rich, Thomas C
American journal of physiology. Cell physiology, vol. 309, (no. 6), pp. C415-C424, September 15, 2015. | Journal Article
 
Modification of Fibers with Nanostructures Using Reactive Dye Chemistry.
Bunge, Meagan ABunge, M.A.Neil Ruckart, KRuckart, K.N.Leavesley, SilasLeavesley, S.Peterson, G.W.Peterson, Gregory WNguyen, NienNguyen, N.West, K.N.West, Kevin NGrant Glover, T and Glover, T.G.
Industrial & engineering chemistry research, vol. 54, (no. 15), pp. 3821-3827, April 22, 2015. | Journal Article
2014
A device for performing automated balloon catheter inflation ischemia studies.
Leavesley, Silas JLedkins, Whitley and Rocic, Petra
PloS one, vol. 9, (no. 4), pp. e95823, 2014. | Journal Article
 
Can we decipher the information content contained within cyclic nucleotide signals?
Rich, Thomas CWebb, Kristal J and Leavesley, Silas J
The Journal of general physiology, vol. 143, (no. 1), pp. 17-27, January 2014. | Journal Article
 
Excitation-scanning hyperspectral imaging microscope.
Favreau, Peter FHernandez, ClarissaHeaster, TiffanyAlvarez, Diego FRich, Thomas CPrabhat, Prashant and Leavesley, Silas J
Journal of biomedical optics, vol. 19, (no. 4), pp. 46010, 2014/Apr/1. | Journal Article
 
FRET: signals hidden within the noise.
Leavesley, Silas J and Rich, Thomas C
Cytometry. Part A : the journal of the International Society for Analytical Cytology, vol. 85, (no. 11), pp. 918-920, November 2014. | Journal Article
 
Thin-film tunable filters for hyperspectral fluorescence microscopy.
Favreau, PeterHernandez, ClarissaLindsey, Ashley SAlvarez, Diego FRich, ThomasPrabhat, Prashant and Leavesley, Silas J
Journal of biomedical optics, vol. 19, (no. 1), pp. 011017, 2014/Jan. | Journal Article
2013
An approach for characterizing and comparing hyperspectral microscopy systems.
Annamdevula, Naga SSweat, BrennerFavreau, PeterLindsey, Ashley SAlvarez, Diego FRich, Thomas C and Leavesley, Silas J
Sensors (Basel, Switzerland), vol. 13, (no. 7), pp. 9267-93, 2013. | Journal Article
 
Assessing FRET using spectral techniques.
Leavesley, Silas JBritain, Andrea LCichon, Lauren KNikolaev, Viacheslav O and Rich, Thomas C
Cytometry. Part A : the journal of the International Society for Analytical Cytology, vol. 83, (no. 10), pp. 898-912, October 2013. | Journal Article
 
Hyperspectral imaging of FRET-based cGMP probes.
Rich, Thomas CBritain, Andrea LStedman, Tiffany and Leavesley, Silas J
Methods in molecular biology (Clifton, N.J.), vol. 1020, pp. 73-88, 2013. | Journal Article
 
MicroRNAs as potential clinical biomarkers: emerging approaches for their detection.
Srivastava, S KBhardwaj, ALeavesley, S JGrizzle, W ESingh, S and Singh, A P
Biotechnic & histochemistry : official publication of the Biological Stain Commission, vol. 88, (no. 7), pp. 373-387, October 2013. | Journal Article
2012
Assessment of cellular mechanisms contributing to cAMP compartmentalization in pulmonary microvascular endothelial cells
Feinstein, Wei PZhu, BingLeavesley, Silas JSayner, Sarah L and Rich, Thomas C
American Journal of Physiology, vol. 302, (no. 6), Mar 2012. | Journal Article
 
Hyperspectral imaging microscopy for identification and quantitative analysis of fluorescently-labeled cells in highly autofluorescent tissue.
Leavesley, Silas JAnnamdevula, NagaBoni, JohnStocker, SamanthaGrant, KristinTroyanovsky, BorisRich, Thomas C and Alvarez, Diego F
Journal of biophotonics, vol. 5, (no. 1), pp. 67-84, 2012/Jan. | Journal Article