28 Publications (Page 1 of 2)
2018
Spectral imaging of FRET-based sensors reveals sustained cAMP gradients in three spatial dimensions.
Annamdevula, Naga SSweat, RachelGriswold, John RTrinh, KennyHoffman, ChaseWest, SavannahDeal, JoshuaBritain, Andrea LJalink, KeesRich, Thomas C and Leavesley, Silas J
Cytometry. Part A : the journal of the International Society for Analytical Cytology, September 3, 2018. | Journal Article
2014
Excitation-scanning hyperspectral imaging microscope.
Favreau, Peter FHernandez, ClarissaHeaster, TiffanyAlvarez, Diego FRich, Thomas CPrabhat, Prashant and Leavesley, Silas J
Journal of biomedical optics, vol. 19, (no. 4), pp. 46010, 2014/Apr/1. | Journal Article
2013
An approach for characterizing and comparing hyperspectral microscopy systems.
Annamdevula, Naga SSweat, BrennerFavreau, PeterLindsey, Ashley SAlvarez, Diego FRich, Thomas C and Leavesley, Silas J
Sensors (Basel, Switzerland), vol. 13, (no. 7), pp. 9267-93, 2013. | Journal Article
 
Hyperspectral imaging of FRET-based cGMP probes.
Rich, Thomas CBritain, Andrea LStedman, Tiffany and Leavesley, Silas J
Methods in molecular biology (Clifton, N.J.), vol. 1020, pp. 73-88, 2013. | Journal Article
2012
Assessment of cellular mechanisms contributing to cAMP compartmentalization in pulmonary microvascular endothelial cells
Feinstein, Wei PZhu, BingLeavesley, Silas JSayner, Sarah L and Rich, Thomas C
American Journal of Physiology, vol. 302, (no. 6), Mar 2012. | Journal Article
 
Calcineurin regulates homologous desensitization of natriuretic peptide receptor-A and inhibits ANP-induced testosterone production in MA-10 cells.
Henesy, Michelle BBritain, Andrea LZhu, BingAmable, LaurenHonkanen, Richard ECorbin, Jackie DFrancis, Sharron H and Rich, Thomas C
PloS one, vol. 7, (no. 8), pp. e41711, 2012. | Journal Article
 
Hyperspectral imaging microscopy for identification and quantitative analysis of fluorescently-labeled cells in highly autofluorescent tissue.
Leavesley, Silas JAnnamdevula, NagaBoni, JohnStocker, SamanthaGrant, KristinTroyanovsky, BorisRich, Thomas C and Alvarez, Diego F
Journal of biophotonics, vol. 5, (no. 1), pp. 67-84, 2012/Jan. | Journal Article
2011
Inactivation of multidrug resistance proteins disrupts both cellular extrusion and intracellular degradation of cAMP.
Xie, MosesRich, Thomas CScheitrum, ColleenConti, Marco and Richter, Wito
Molecular pharmacology, vol. 80, (no. 2), pp. 281-93, 2011/Aug. | Journal Article
 
PDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblasts.
Blackman, Brigitte EHorner, KathleenHeidmann, JuliaWang, DanRichter, WitoRich, Thomas C and Conti, Marco
The Journal of biological chemistry, vol. 286, (no. 14), pp. 12590-601, 2011/Apr/8. | Journal Article
2010
Quantitative modeling of GRK-mediated beta2AR regulation.
Vayttaden, Sharat JVayttaden, Sharat JFriedman, JacquelineFriedman, JacquelineTran, Tuan MTran, Tuan MRich, Thomas CRich, Thomas CDessauer, Carmen WDessauer, Carmen WClark, Richard B and Clark, Richard B
PLoS computational biology, vol. 6, (no. 1), pp. e1000647, 2010/Jan. | Journal Article
2009
Receptor reserve reflects differential intrinsic efficacy associated with opioid diastereomers
Carliss, RDSKeefer, JFPerschke, S.Welch, S.Rich, Thomas C and Weissman, AD
Pharmacology Biochemistry and Behavior, vol. 92, (no. 3), pp. 495-502, 2009. | Journal Article
2008
Roles of GRK and PDE4 activities in the regulation of beta2 adrenergic signaling.
Xin, WenkuanTran, Tuan MRichter, WitoClark, Richard B and Rich, Thomas C
The Journal of general physiology, vol. 131, (no. 4), pp. 349-64, 2008/Apr. | Journal Article
2007
Cellular mechanisms underlying prostaglandin-induced transient cAMP signals near the plasma membrane of HEK-293 cells.
Rich, Thomas CXin, WenkuanMehats, CelineHassell, Kathryn APiggott, Leslie ALe, XuanKarpen, Jeffrey W and Conti, Marco
American journal of physiology. Cell physiology, vol. 292, (no. 1), pp. C319-31, 2007/Jan. | Journal Article
2006
Natriuretic Peptides and Nitric Oxide Stimulate cGMP Synthesis in Different Cellular Compartments
Piggott, Leslie AHassell, Kathryn ABerkova, ZuzanaMorris, Andrew PSilberbach, Michael and Rich, Thomas C
Journal of General Physiology, vol. 128, (no. 1), pp. 3-14, 2006. | Journal Article
2005
High-throughput screening of phosphodiesterase activity in living cells.
Rich, Thomas C and Karpen, Jeffrey W
Methods in molecular biology (Clifton, N.J.), vol. 307, pp. 45-61, 2005. | Journal Article
2004
Functional role of lipid raft microdomains in cyclic nucleotide-gated channel activation.
Brady, J. D.Brady, James DBrady, J.D.Rich, Thomas CRich, T. C.Rich, T.C.Le, XuanLe, X.Stafford, K.Stafford, KimberleeFowler, C.J.Fowler, Cedar JLynch, LeathaLynch, L.Karpen, Jeffrey WKarpen, J.W.Brown, R.L.Brown, R LMartens, Jeff and Martens, J.R.
Molecular pharmacology, vol. 65, (no. 3), pp. 503-11, 2004/Mar. | Journal Article
2003
Probing the roles of protein kinases in g-protein-coupled receptor desensitization.
Clark, Richard B and Rich, Thomas C
Molecular pharmacology, vol. 64, (no. 5), pp. 1015-7, 2003/Nov. | Journal Article
2002
Mutations throughout the S6 region of the hKv1.5 channel alter the stability of the activation gate.
Rich, Thomas CYeola, Sarita WTamkun, Michael M and Snyders, Dirk J
American journal of physiology. Cell physiology, vol. 282, (no. 1), pp. C161-71, 2002/Jan. | Journal Article
 
Review Article: Cyclic AMP Sensors in Living Cells: What Signals Can They Actually Measure?
Rich, Thomas C and Karpen, Jeffrey W
Annals of Biomedical Engineering, vol. 30, (no. 8), pp. 1088-1099, 2002. | Journal Article
2001
A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell.
Rich, Thomas CFagan, K ATse, T ESchaack, JCooper, Dermot and Karpen, Jeffrey W
Proceedings of the National Academy of Sciences of the United States of America, vol. 98, (no. 23), pp. 13049-54, 2001/Nov/6. | Journal Article
 
In vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as cAMP sensors.
Rich, Thomas CTse, T ERohan, J GSchaack, J and Karpen, Jeffrey W
The Journal of general physiology, vol. 118, (no. 1), pp. 63-78, 2001/Jul. | Journal Article
 
The fourth dimension in cellular signaling.
Karpen, Jeffrey W and Rich, Thomas C
Science, vol. 293, (no. 5538), pp. 2204-5, 2001/Sep/21. | Journal Article
2000
Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion.
Rich, Thomas CFagan, K ANakata, HSchaack, JCooper, Dermot and Karpen, Jeffrey W
The Journal of General Physiology, vol. 116, (no. 2), pp. 147-61, 2000/Aug. | Journal Article
1999
Adenovirus-mediated expression of an olfactory cyclic nucleotide-gated channel regulates the endogenous Ca2+-inhibitable adenylyl cyclase in C6-2B glioma cells.
Fagan, K ARich, Thomas CTolman, SSchaack, JKarpen, J W and Cooper, D M
The Journal of biological chemistry, vol. 274, (no. 18), pp. 12445-53, 1999/Apr/30. | Journal Article
1998
Evidence for multiple open and inactivated states of the hKv1.5 delayed rectifier.
Rich, Thomas C and Snyders, D J
Biophysical journal, vol. 75, (no. 1), pp. 183-95, 1998/Jul. | Journal Article