67 Publications (Page 1 of 3)
2014
Mitochondrial Targeted Endonuclease III DNA Repair Enzyme Protects against Ventilator Induced Lung Injury in Mice.
Hashizume, Masahiro⋅Mouner, Marc⋅Chouteau, Joshua M⋅Gorodnya, Olena M⋅Ruchko, Mykhaylo V⋅Wilson, Glenn L⋅Gillespie, Mark N and Parker, James C
Pharmaceuticals (Basel, Switzerland), vol. 7, (no. 8), pp. 894-912, 2014. | Journal Article
2013
Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: role of ogg1.
Yuzefovych, Larysa V⋅Schuler, A M⋅Chen, Jemimah⋅Alvarez, Diego F⋅Eide, Lars⋅Le Doux, Susan P⋅Wilson, Glenn L and Rachek, Lyudmila I
Endocrinology, vol. 154, (no. 8), pp. 2640-9, 2013/Aug. | Journal Article
 
Mitochondrial DNA damage and dysfunction, and oxidative stress are associated with endoplasmic reticulum stress, protein degradation and apoptosis in high fat diet-induced insulin resistance mice.
Yuzefovych, Larysa V⋅Yuzefovych, Larysa V⋅Musiyenko, Sergiy I⋅Musiyenko, Sergiy I⋅Wilson, Glenn L⋅Wilson, Glenn L⋅Rachek, Lyudmila I and Rachek, Lyudmila I
PloS one, vol. 8, (no. 1), pp. e54059, 2013. | Journal Article
 
Mitochondrial DNA damage mediates hyperoxic dysmorphogenesis in rat fetal lung explants.
Gebb, Sarah A⋅De Coux, Ashley⋅Waggoner, Alicia⋅Wilson, Glenn L and Gillespie, Mark
Neonatology, vol. 103, (no. 2), pp. 91-7, 2013. | Journal Article
 
Mitochondrial DNA ligase is dispensable for the viability of cultured cells but essential for mtDNA maintenance.
Shokolenko, Inna N⋅Fayzulin, Rafik Z⋅Katyal, Sachin⋅Mc Kinnon, Peter J⋅Wilson, Glenn L and Alexeyev, Mikhail F
The Journal of biological chemistry, vol. 288, (no. 37), pp. 26594-605, 2013/Sep/13. | Journal Article
 
Mitochondrial-targeted DNA repair enzyme 8-oxoguanine DNA glycosylase 1 protects against ventilator-induced lung injury in intact mice.
Hashizume, Masahiro⋅Mouner, Marc⋅Chouteau, Joshua M⋅Gorodnya, Olena M⋅Ruchko, Mykhaylo V⋅Potter, Barry J⋅Wilson, Glenn L⋅Gillespie, Mark and Parker, James C
American journal of physiology. Lung cellular and molecular physiology, vol. 304, (no. 4), pp. L287-97, 2013/Feb/15. | Journal Article
 
Persistent damage induces mitochondrial DNA degradation.
Shokolenko, Inna N⋅Wilson, Glenn L and Alexeyev, Mikhail F
DNA repair, vol. 12, (no. 7), pp. 488-99, 2013/Jul. | Journal Article
2012
Protection from Palmitate-Induced Mitochondrial DNA Damage Prevents from Mitochondrial Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Impaired Insulin Signaling in Rat L6 Skeletal Muscle Cells
Yuzefovych, Larysa V⋅Solodushko, Viktoriya A⋅Wilson, Glenn L and Rachek, Lyudmila I
Endocrinology, vol. 153, (no. 1), pp. 92-100, 2012. | Journal Article
2011
Mitochondrial DNA integrity may be a determinant of endothelial barrier properties in oxidant-challenged rat lungs
Chouteau, Joshua M⋅Obiako, Boniface⋅Gorodnya, Olena M⋅Pastukh, Viktor⋅Ruchko, Mykhaylo V⋅Wright, Anthony J⋅Wilson, Glenn L and Gillespie, Mark
American Journal of Physiology, vol. 301, (no. 6), Dec 2011. | Journal Article
2010
The approaches for manipulating mitochondrial proteome.
Shokolenko, Inna N⋅Alexeyev, Mikhail F⋅Le Doux, Susan P and Wilson, Glenn L
Environmental and molecular mutagenesis, vol. 51, (no. 5), pp. 451-61, 2010/Jun. | Journal Article
2009
Chapter 15: Targeting Repair Proteins to the Mitochondria of Mammalian Cells Through Stable Transfection, Transient Transfection, Viral Transduction, and TAT-Mediated Protein Transduction
Koczor, CA⋅Snyder, JW⋅Shokolenko, IN⋅Dobson, Allison W⋅Wilson, Glenn L and Le Doux, Susan P
Methods in Molecular Biology, vol. 554, pp. 233-249, 2009. | Journal Article
 
Effects of Hyaluronic Acid on Mitochondrial Function and Mitochondria-driven Apoptosis following Oxidative Stress in Human Chondrocytes
Grishko, Valentina⋅Xu, Min⋅Ho, Renee⋅Mates, Aaron⋅Watson, Scott⋅Kim, Jong T⋅Wilson, Glenn L and Pearsall, Albert W
Journal of biological chemistry., vol. 284, (no. 14), pp. 9132-9139, 2009. | Journal Article
 
Hypoxia-induced oxidative base modifications in the VEGF hypoxia-response element are associated with transcriptionally active nucleosomes
Ruchko, Mykhaylo V⋅Gorodnya, Olena M⋅Pastukh, Viktor⋅Swiger, Brad M⋅Middleton, Natavia S⋅Wilson, Glenn L and Gillespie, Mark
Free Radical Biology and Medicine, vol. 46, (no. 3), pp. 352-359, 2009. | Journal Article
 
Mitochondrial DNA Damage Initiates a Cell Cycle Arrest by a Chk2-associated Mechanism in Mammalian Cells
Koczor, Christopher A⋅Shokolenko, Inna N⋅Boyd, Amy K⋅Balk, Shawn P⋅Wilson, Glenn L and Le Doux, Susan P
Journal of Biological Chemistry, vol. 284, (no. 52), pp. 36191-36201, 2009. | Journal Article
 
Oxidative stress induces degradation of mitochondrial DNA
Shokolenko, Inna⋅Venediktova, Natalia⋅Bochkareva, Alexandra⋅Wilson, Glenn L and Alexeyev, Mikhail F
Nucleic Acids Research, vol. 37, (no. 8), pp. 2539-2548, 2009. | Journal Article
 
Targeting repair proteins to the mitochondria of mammalian cells through stable transfection, transient transfection, viral transduction, and TAT-mediated protein transduction.
Koczor, Christopher A⋅Snyder, Janet W⋅Shokolenko, Inna N⋅Dobson, Allison W⋅Wilson, Glenn L and Le Doux, Susan P
Methods in molecular biology (Clifton, N.J.), vol. 554, pp. 233-49, 2009. | Journal Article
 
Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes.
Rachek, Lyudmila I⋅Yuzefovych, Larysa V⋅Le Doux, Susan P⋅Julie, Neil L and Wilson, Glenn L
Toxicology and applied pharmacology, vol. 240, (no. 3), pp. 348-54, 2009/Nov/1. | Journal Article
2008
Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis
Ricci, Craig⋅Ricci, Craig⋅Ricci, Craig⋅Pastukh, Viktor⋅Pastukh, Viktor⋅Pastukh, Viktor⋅Leonard, Josh⋅Leonard, Joshua N⋅Leonard, Josh⋅Turrens, Julio⋅Turrens, Julio⋅Turrens, Julio⋅Wilson, Glenn⋅Wilson, Glenn L⋅Wilson, Glenn⋅Schaffer, David⋅Schaffer, David⋅Schaffer, David V⋅Schaffer, Stephen W⋅Schaffer, Stephen W and Schaffer, Stephen W
American Journal of Physiology, vol. 294, (no. 2), Feb 2008. | Journal Article
 
Mitochondrial DNA repair in aging and disease
Druzhyna, Nadiya M⋅Wilson, Glenn L and Le Doux, Susan P
Mechanisms of Ageing and Development, vol. 129, (no. 7-8), pp. 383-390, 2008. | Journal Article
 
Mutations in the passenger polypeptide can affect its partitioning between mitochondria and cytoplasm
Pastukh, Viktoriya⋅Shokolenko, Inna N⋅Wilson, Glenn L and Alexeyev, Mikhail F
Molecular biology reports., vol. 35, (no. 2), pp. 215-223, 2008. | Journal Article
 
Mutations in the passenger polypeptide can affect its partitioning between mitochondria and cytoplasm: mutations can impair the mitochondrial import of DsRed.
Pastukh, Viktoriya⋅Shokolenko, Inna N⋅Wilson, Glenn L and Alexeyev, Mikhail F
Molecular biology reports, vol. 35, (no. 2), pp. 215-23, 2008/Jun. | Journal Article
 
Selective elimination of mutant mitochondrial genomes as therapeutic strategy for the treatment of NARP and MILS syndromes
Alexeyev, M⋅Venediktova, N⋅Pastukh, V⋅Shokolenko, I⋅Bonilla, G and Wilson, G
Gene Therapy, vol. 15, (no. 7), pp. 516-23, Apr 2008. | Journal Article
 
Selective elimination of mutant mitochondrial genomes as therapeutic strategy for the treatment of NARP and MILS syndromes
Alexeyev, Mikhail F⋅Venediktova, N⋅Pastukh, Viktor⋅Shokolenko, I⋅Bonilla, G and Wilson, Glenn L
Gene Therapy, vol. 15, (no. 7), pp. 516-23, Apr 2008. | Journal Article
2007
Altering DNA base excision repair: Use of nuclear and mitochondrial-targeted N-methylpurine DNA glycosylase to sensitize astroglia to chemotherapeutic agents
Harrison, Jason F⋅Rinne, Mikael L⋅Kelley, Mark R⋅Druzhyna, Nadiya M⋅Wilson, Glenn L⋅Le Doux, Susan P and Ledoux, Susan P
Glia, vol. 55, (no. 14), pp. 1416-1425, 2007. | Journal Article
 
Mitochondrial DNA repair: a critical player in the response of cells of the CNS to genotoxic insults.
Le Doux, Susan P⋅Druzhyna, N M⋅Hollensworth, S B⋅Harrison, J F and Wilson, Glenn L
Neuroscience, vol. 145, (no. 4), pp. 1249-59, 2007/Apr/14. | Journal Article