13 Publications
2019
Cannabinoid CB2 Agonist AM1710 Differentially Suppresses Distinct Pathological Pain States and Attenuates Morphine Tolerance and Withdrawal
Li, Ai-Ling⋅Li, Ai-Ling⋅Lin, Xiaoyan⋅Lin, Xiaoyan⋅Dhopeshwarkar, Amey S⋅Dhopeshwarkar, Amey S⋅Thomaz, Ana Carla⋅Thomaz, Ana Carla⋅Carey, Lawrence M⋅Carey, Lawrence M⋅Liu, Yingpeng⋅Liu, Yingpeng⋅Nikas, Spyros P⋅Nikas, Spyros P⋅Makriyannis, Alexandros⋅Makriyannis, Alexandros⋅Mackie, Ken⋅Mackie, Ken⋅Hohmann, Andrea G and Hohmann, Andrea G
Molecular pharmacology, vol. 95, (no. 2), pp. 168, 2019-02-00. | Journal Article
2018
Slowly Signaling G Protein-Biased CB 2 Cannabinoid Receptor Agonist LY2828360 Suppresses Neuropathic Pain with Sustained Efficacy and Attenuates Morphine Tolerance and Dependence
Lin, Xiaoyan⋅Lin, Xiaoyan⋅Dhopeshwarkar, Amey S⋅Dhopeshwarkar, Amey S⋅Huibregtse, Megan⋅Huibregtse, Megan⋅Mackie, Ken⋅Mackie, Ken⋅Hohmann, Andrea G and Hohmann, Andrea G
Molecular pharmacology, vol. 93, (no. 2), pp. 49, 2018-02-00. | Journal Article
 
Slowly Signaling G Protein–Biased CB2 Cannabinoid Receptor Agonist LY2828360 Suppresses Neuropathic Pain with Sustained Efficacy and Attenuates Morphine Tolerance and Dependence
Lin, Xiaoyan⋅Lin, Xiaoyan⋅Lin, Xiaoyan⋅Dhopeshwarkar, Amey S⋅Dhopeshwarkar, Amey S⋅Dhopeshwarkar, Amey S⋅Huibregtse, Megan⋅Huibregtse, Megan⋅Huibregtse, Megan⋅Mackie, Ken⋅Mackie, Ken⋅Mackie, Ken⋅Hohmann, Andrea G⋅Hohmann, Andrea G and Hohmann, Andrea G
Molecular Pharmacology, vol. 93, (no. 2), pp. 62, 2018-02-00. | Journal Article
2017
Synthesis of Photoswitchable 9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling
Westphal, Matthias⋅Schafroth, Michael⋅Sarott, Roman⋅Imhof, Michael⋅Bold, Christian⋅Leippe, Philipp⋅Dhopeshwarkar, Amey⋅Grandner, Jessica⋅Katritch, Vsevolod⋅Mackie, Ken⋅Trauner, Dirk⋅Carreira, Erick and Frank, James
Journal of the American Chemical Society, vol. 139, (no. 50), pp. 18206, 20171220. | Journal Article
 
Synthesis of Photoswitchable Δ 9 -Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling
Westphal, Matthias V⋅Schafroth, Michael A⋅Sarott, Roman C⋅Imhof, Michael A⋅Bold, Christian P⋅Leippe, Philipp⋅Dhopeshwarkar, Amey⋅Grandner, Jessica M⋅Katritch, Vsevolod⋅Mackie, Ken⋅Trauner, Dirk⋅Carreira, Erick M and Frank, James A
Journal of the American Chemical Society, vol. 139, (no. 50), pp. 18206, 2017-12-20. | Journal Article
 
Synthesis of Photoswitchable Δ9‑Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling
Westphal, Matthias V⋅Schafroth, Michael A⋅Sarott, Roman C⋅Imhof, Michael A⋅Bold, Christian P⋅Leippe, Philipp⋅Dhopeshwarkar, Amey⋅Grandner, Jessica M⋅Katritch, Vsevolod⋅Mackie, Ken⋅Trauner, Dirk⋅Carreira, Erick M and Frank, James A
Journal of the American Chemical Society, vol. 139, (no. 50), pp. 18212, 20171220. | Journal Article
 
Two Janus Cannabinoids That Are Both CB2 Agonists and CB1 Antagonists
Dhopeshwarkar, Amey⋅Dhopeshwarkar, Amey⋅Murataeva, Natalia⋅Murataeva, Natalia⋅Makriyannis, Alex⋅Makriyannis, Alex⋅Straiker, Alex⋅Straiker, Alex⋅Mackie, Ken and Mackie, Ken
The Journal of pharmacology and experimental therapeutics, vol. 360, (no. 2), pp. 311, 2017-Feb. | Journal Article
2016
Functional Selectivity of CB2 Cannabinoid Receptor Ligands at a Canonical and Noncanonical Pathway
Dhopeshwarkar, Amey and Mackie, Ken
The Journal of pharmacology and experimental therapeutics, vol. 358, (no. 2), pp. 351, 2016-08-00. | Journal Article
 
Where’s my entourage? The curious case of 2-oleoylglycerol, 2-linolenoylglycerol, and 2-palmitoylglycerol
Murataeva, Natalia⋅Murataeva, Natalia⋅Murataeva, Natalia⋅Dhopeshwarkar, Amey⋅Dhopeshwarkar, Amey⋅Dhopeshwarkar, Amey⋅Yin, Danielle⋅Yin, Danielle⋅Yin, Danielle⋅Mitjavila, José⋅Mitjavila, José⋅Mitjavila, José⋅Bradshaw, Heather⋅Bradshaw, Heather⋅Bradshaw, Heather⋅Straiker, Alex⋅Straiker, Alex⋅Straiker, Alex⋅Mackie, Ken⋅Mackie, Ken and Mackie, Ken
Pharmacological Research, vol. 110, pp. 180, August 2016. | Journal Article
2014
Benzophenanthridine alkaloid, piperonyl butoxide and (S)-methoprene action at the cannabinoid-1 receptor (CB1-receptor) pathway of mouse brain: Interference with [3H]CP55940 and [3H]SR141716A binding and modification of WIN55212-2-dependent inhibition of synaptosomal l-glutamate release
Dhopeshwarkar, Amey Sadashiv and Nicholson, Russell Alfred
European Journal of Pharmacology, vol. 723, pp. 441, 2014-01-15. | Journal Article
 
CB2 Cannabinoid Receptors as a Therapeutic Target--What Does the Future Hold?
Dhopeshwarkar, Amey and Mackie, Ken
Molecular pharmacology, vol. 86, (no. 4), pp. 437, 2014-Oct. | Journal Article
2011
The actions of benzophenanthridine alkaloids, piperonyl butoxide and (S)-methoprene at the G-protein coupled cannabinoid CB1 receptor in vitro
Dhopeshwarkar, Amey S⋅Dhopeshwarkar, Amey S⋅Jain, Saurabh⋅Jain, Saurabh⋅Liao, Chengyong⋅Liao, Chengyong⋅Ghose, Sudip K⋅Ghose, Sudip K⋅Bisset, Kathleen M⋅Bisset, Kathleen M⋅Nicholson, Russell A and Nicholson, Russell A
European Journal of Pharmacology, vol. 654, (no. 1), pp. 32, 2011-03-01. | Journal Article
 
The G protein-coupled cannabinoid-1 (CB1) receptor of mammalian brain: Inhibition by phthalate esters in vitro
Bisset, Kathleen M⋅Bisset, Kathleen M⋅Dhopeshwarkar, Amey S⋅Dhopeshwarkar, Amey S⋅Liao, Chengyong⋅Liao, Chengyong⋅Nicholson, Russell A and Nicholson, Russell A
Neurochemistry International, vol. 59, (no. 5), pp. 713, October 2011. | Journal Article