The endocannabinoid system consists of endogenous cannabinoids (endocannabinoids), cannabinoid receptors (primarily CB1 and CB2), and the enzymes that synthesize and degrade endocannabinoids. Δ9-Tetrahydrocannabinol (Δ9-THC), the primary psychoactive component of cannabis, produces many of its psychoactive effects by engaging CB1 cannabinoid receptors. In addition to its psychoactivity, cannabis has been shown (or suggested) to be efficacious for multiple therapeutic indications and maladies. My interest in cannabinoid receptors stems from my graduate studies.
My long-term research goal is to dissect the complex cellular signaling pathways that are recruited following the activation of GPR119 and other cannabinoid receptors and how this knowledge can be harnessed for therapeutic benefit.