Clinical Interests: Understand the molecular pathogenesis of two genetic diseases that result in malignancies and tumors, with a focus in the role of the NF1 tumor suppressor gene. Study the cellular and biochemical functions of the disorder Fanconi anemia.

Our laboratory focuses on the molecular pathogenesis of neurofibromatosis type 1 and neurofibromatosis type 2. Neurofibromatosis type 1 is the most common genetic disease with a predisposition to cancer and one of a series of developmental disorders called Rasopathies that have a range of malignant, neurodevelopmental and other non-malignant disease manifestations.

MD, Indiana University School of Medicine, 1982
BA, Hanover College, 1977