42 Publications (Page 1 of 2)
2018
NFM-01. NF105: A PHASE II PROSPECTIVE STUDY OF CABOZANTINIB (XL184) FOR PLEXIFORM NEUROFIBROMAS IN SUBJECTS WITH NEUROFIBROMATOSIS TYPE 1: A NEUROFIBROMATOSIS CLINICAL TRIAL CONSORTIUM (NFCTC) STUDY
Shih, Chie-Schin⋅Shih, Chie Schin⋅Shih, Chie-Schin⋅Blakely, Jaishri⋅Blakely, Jaishri⋅Blakely, Jaishri⋅Clapp, Wade⋅Clapp, Wade⋅Clapp, Wade⋅Wolters, Pam⋅Wolters, Pam⋅Wolters, Pam⋅Dombi, Eva⋅Dombi, Eva⋅Dombi, Eva⋅Cutter, Gary⋅Cutter, Gary⋅Cutter, Gary⋅Ullrich, Nichole⋅Ullrich, Nichole⋅Ullrich, Nichole⋅Allen, Jeffrey⋅Allen, Jeffrey⋅Allen, Jeffrey⋅Packer, Roger⋅Packer, Roger⋅Packer, Roger⋅Goldman, Stewart⋅Goldman, Stewart⋅Goldman, Stewart⋅Gutmann, David⋅Gutmann, David⋅Gutmann, David⋅Plotkin, Scott⋅Plotkin, Scott⋅Plotkin, Scott⋅Rosser, Tena⋅Rosser, Tena⋅Rosser, Tena⋅Robertson, Kent⋅Robertson, Kent⋅Robertson, Kent⋅Widemann, Brigitte⋅Widemann, Brigitte⋅Widemann, Brigitte⋅Korf, Bruce⋅Korf, Bruce⋅Korf, Bruce⋅Fisher, Michael⋅Fisher, Michael and Fisher, Michael
Neuro-Oncology, vol. 20, (no. suppl_2), pp. i142, 20180622. | Journal Article
2017
RARE-19. MULTICENTER, PHASE 2 STUDY OF BEVACIZUMAB IN CHILDREN AND ADULTS WITH NEUROFIBROMATOSIS 2 AND PROGRESSIVE VESTIBULAR SCHWANNOMAS: AN NF CLINICAL TRIALS CONSORTIUM STUDY
Plotkin, Scott⋅Tonsgard, James⋅Ullrich, Nicole⋅Allen, Jeffrey⋅Blakeley, Jashri⋅Rosser, Tena⋅Campian, Jian⋅Clapp, Wade⋅Fisher, Michael⋅Cutter, Gary⋅Korf, Bruce⋅Packer, Roger⋅Thomas, Coretta and Karjannis, Matthias
Neuro-Oncology, vol. 19, (no. suppl_6), pp. vi215, 2017-11-06. | Journal Article
 
The path forward: 2015 International Children's Tumor Foundation conference on neurofibromatosis type 1, type 2, and schwannomatosis
Blakeley, Jaishri O⋅Blakeley, Jaishri O⋅Bakker, Annette⋅Bakker, Annette⋅Barker, Anne⋅Barker, Anne⋅Clapp, Wade⋅Clapp, Wade⋅Ferner, Rosalie⋅Ferner, Rosalie⋅Fisher, Michael J⋅Fisher, Michael J⋅Giovannini, Marco⋅Giovannini, Marco⋅Gutmann, David H⋅Gutmann, David H⋅Karajannis, Matthias A⋅Karajannis, Matthias A⋅Kissil, Joseph L⋅Kissil, Joseph L⋅Legius, Eric⋅Legius, Eric⋅Lloyd, Alison C⋅Lloyd, Alison C⋅Packer, Roger J⋅Packer, Roger J⋅Ramesh, Vijaya⋅Ramesh, Vijaya⋅Riccardi, Vincent M⋅Riccardi, Vincent M⋅Stevenson, David A⋅Stevenson, David A⋅Ullrich, Nicole J⋅Ullrich, Nicole J⋅Upadhyaya, Meena⋅Upadhyaya, Meena⋅Stemmer-Rachamimov, Anat and Stemmer‐Rachamimov, Anat
American Journal of Medical Genetics Part A, vol. 173, (no. 6), pp. 1721, June 2017. | Journal Article
2016
Phase II Study of the MEK 1/2 inhibitor selumetinib (AZD6244, ARRY-142886) in children with neurofibromatosis type 1 (NF1) and inoperable plexiform neurofibromas (PN)
Gross, Andrea M⋅Baldwin, Andrea⋅Dombi, Eva⋅Wolters, Pamela⋅Whitcomb, Patricia⋅Holmblad, Marielle⋅Martin, Staci⋅Fisher, Michael J⋅Kim, AeRang⋅Weiss, Brian D⋅Paul, Scott M⋅Clapp, Wade⋅Farrell, Kathleen⋅Smith, Michaele⋅Fontana, Joseph⋅Brofferio, Alessandra⋅Steinberg, Seth M⋅Doyle, Laurence A and Widemann, Brigitte C
Journal of Clinical Oncology, vol. 34, (no. 15_suppl), pp. TPS10586, 2016-05-20. | Journal Article
 
Phase II trial of the MEK1/2 inhibitor selumetinib (AZD6244) in adults with neurofibromatosis type 1 (NF1) and inoperable plexiform neurofibromas (PNs)
Bradford, Diana⋅Whitcomb, Patricia⋅Dombi, Eva⋅Chen, Alice P⋅Baldwin, Andrea⋅Wolters, Pamela⋅Martin, Staci⋅Glod, John⋅Derdak, Joanne⋅O'Sullivan Coyne, Geraldine Helen⋅Cowen, Edward W⋅Holmblad, Marielle⋅Trepel, Jane⋅Wood, Bradford J⋅Paul, Scott M⋅Clapp, Wade⋅Johnson, Gary L⋅Rubinstein, Larry⋅Doyle, L. Austin and Widemann, Brigitte C
Journal of Clinical Oncology, vol. 34, (no. 15_suppl), pp. TPS2596, 2016-05-20. | Journal Article
2014
Abstract LB-79: PRC2 loss amplifies Ras-driven transcription and sensitizes cancers to bromodomain inhibitor-based combination therapies
Raedt, Thomas D⋅Beert, Eline⋅Pasmant, Eric⋅Luscan, Armelle⋅Brems, Hilde⋅Ortonne, Nicolas⋅Helin, Kristian⋅Mautner, Victor⋅Kehrer-Sawatski, Hildegard⋅Clapp, Wade⋅Bradner, James⋅Upadhyaya, Meena⋅Vidaud, Michel⋅Legius, Eric and Cichowski, Karen
Cancer Research, vol. 74, (no. 19 Supplement), pp. LB-79, 2014-10-01. | Journal Article
 
PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies
De Raedt, Thomas⋅De Raedt, Thomas⋅De Raedt, Thomas⋅Beert, Eline⋅Beert, Eline⋅Beert, Eline⋅Pasmant, Eric⋅Pasmant, Eric⋅Pasmant, Eric⋅Luscan, Armelle⋅Luscan, Armelle⋅Luscan, Armelle⋅Brems, Hilde⋅Brems, Hilde⋅Brems, Hilde⋅Ortonne, Nicolas⋅Ortonne, Nicolas⋅Ortonne, Nicolas⋅Helin, Kristian⋅Helin, Kristian⋅Helin, Kristian⋅Hornick, Jason L⋅Hornick, Jason L⋅Hornick, Jason L⋅Mautner, Victor⋅Mautner, Victor⋅Mautner, Victor⋅Kehrer-Sawatzki, Hildegard⋅Kehrer-Sawatzki, Hildegard⋅Kehrer-Sawatzki, Hildegard⋅Clapp, Wade⋅Clapp, Wade⋅Clapp, Wade⋅Bradner, James⋅Bradner, James⋅Bradner, James⋅Vidaud, Michel⋅Vidaud, Michel⋅Vidaud, Michel⋅Upadhyaya, Meena⋅Upadhyaya, Meena⋅Upadhyaya, Meena⋅Legius, Eric⋅Legius, Eric⋅Legius, Eric⋅Cichowski, Karen⋅Cichowski, Karen and Cichowski, Karen
Nature, vol. 514, (no. 7521), pp. 251, 2014-Oct-09. | Journal Article
2013
Abstract 355: Generation of a murine model of Neurofibromatosis Type 2 that accurately recapitulates the spontaneous development of vestibular and spinal schwannomas found in NF2 patients
Gehlhausen, Jeff R⋅Park, Su Jung⋅Shew, Matthew⋅Clapp, Wade and Yates, Charles
Cancer Research, vol. 73, (no. 8 Supplement), pp. 355, 2013-04-15. | Journal Article
2008
Nf1+/− mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway
Lasater, Elisabeth A⋅Lasater, Elisabeth A.⋅Bessler, Waylan K⋅Bessler, Waylan K.⋅Mead, Laura E⋅Mead, Laura E.⋅Horn, Whitney E⋅Horn, Whitney E.⋅Clapp, D. Wade⋅Clapp, David W⋅Conway, Simon⋅Conway, Simon J.⋅Ingram, David A⋅Ingram, David A.⋅Li, Fang and Li, Fang
Human molecular genetics, vol. 17, (no. 15), pp. 2344, 2008-08-01. | Journal Article
2006
Developmental Regulation of the Immune System
Clapp, D. W and Clapp, D. Wade
Seminars in perinatology, vol. 30, (no. 2), pp. 72, 2006-04-01. | Journal Article
 
HMGB1 expression and release by bone cells
Charoonpatrapong, Kanokwan⋅Charoonpatrapong, Kanokwan⋅Shah, Rita⋅Shah, Rita⋅Robling, Alexander G.⋅Robling, Alexander⋅Alvarez, Marta⋅Alvarez, Marta⋅Clapp, D. Wade⋅Clapp, D W⋅Chen, Shi⋅Chen, Shi⋅Kopp, Ryan P⋅Kopp, Ryan P.⋅Pavalko, Fredrick M.⋅Pavalko, Fredrick M⋅Yu, Jun⋅Yu, Jun⋅Bidwell, Joseph and Bidwell, Joseph P.
Journal of cellular physiology, vol. 207, (no. 2), pp. 490, 2006-05. | Journal Article
 
Reconstitution of the NF1 GAP-related domain in NF1-deficient human Schwann cells
Thomas, Stacey L⋅Thomas, Stacey L.⋅Deadwyler, Gail D.⋅Deadwyler, Gail D⋅Tang, Jun⋅Tang, Jun⋅Stubbs, Evan B.⋅Stubbs, Evan B⋅Muir, David⋅Muir, David⋅Hiatt, Kelly K⋅Hiatt, Kelly K.⋅Clapp, D. Wade⋅Clapp, D W⋅De Vries, George H. and De Vries, George H
Biochemical and biophysical research communications, vol. 348, (no. 3), pp. 980, 2006-09-29. | Journal Article
2005
Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells
Schubbert, Suzanne⋅Schubbert, Suzanne⋅Lieuw, Kenneth⋅Lieuw, Kenneth⋅Rowe, Sara L.⋅Rowe, Sara L⋅Lee, Connie M⋅Lee, Connie M.⋅Li, Xiaxin⋅Li, XiaXin⋅Loh, Mignon L⋅Loh, Mignon L.⋅Clapp, D. Wade⋅Clapp, D. W⋅Shannon, Kevin M and Shannon, Kevin M.
Blood, vol. 106, (no. 1), pp. 317, 2005-07-01. | Journal Article
 
Sensory Neurons From Nf1 Haploinsufficient Mice Exhibit Increased Excitability
Wang, Yue⋅Wang, Yue⋅Nicol, Grant D⋅Nicol, G.⋅Clapp, D.⋅Clapp, D. W⋅Hingtgen, Cynthia M and Hingtgen, Cynthia
Journal of Neurophysiology, vol. 94, (no. 6), pp. 3676, 2005-12-01. | Journal Article
 
Transcriptional Repression of the Neurofibromatosis-1 Tumor Suppressor by the t(8;21) Fusion Protein
Yang, Genyan⋅Yang, Genyan⋅Khalaf, Waleed⋅Khalaf, Waleed⋅van de Locht, Louis⋅van de Locht, Louis⋅Jansen, Joop H.⋅Jansen, Joop H⋅Gao, Meihua⋅Gao, Meihua⋅Thompson, Mary Ann⋅Thompson Arildsen, Mary A⋅Thompson, Mary Ann⋅van der Reijden, Bert A⋅van der Reijden, Bert A.⋅Gutmann, David H⋅Gutmann, David H.⋅Delwel, Ruud⋅Delwel, Ruud⋅Clapp, D. Wade⋅Clapp, DWade⋅Hiebert, Scott W and Hiebert, Scott W.
Molecular and Cellular Biology, vol. 25, (no. 14), pp. 5879, 2005-07-01. | Journal Article
2004
A Positive Role for the Ku Complex in DNA Replication Following Strand Break Damage in Mammals
Park, Su-Jung⋅Park, Su-Jung⋅Ciccone, Samantha L.M.⋅Ciccone, Samantha L⋅Freie, Brian⋅Freie, Brian⋅Kurimasa, Akihiro⋅Kurimasa, Akihiro⋅Chen, David J⋅Chen, David J.⋅Li, Gloria C⋅Li, Gloria C.⋅Clapp, D. Wade⋅Clapp, D. W⋅Lee, Suk-Hee and Lee, Suk Hee
The Journal of biological chemistry, vol. 279, (no. 7), pp. 6055, 2004-02-13. | Journal Article
 
Continuous in vivo infusion of interferon-gamma (IFN-γ) preferentially reduces myeloid progenitor numbers and enhances engraftment of syngeneic wild-type cells in Fancc-/- mice
Li, Xiaxin⋅Li, Xiaxin⋅Yang, Yanzhu⋅Yang, Yanzhu⋅Yuan, Jin⋅Yuan, Jin⋅Hong, Ping⋅Hong, Ping⋅Freie, Brian⋅Freie, Brian⋅Orazi, Attilio⋅Orazi, Attilio⋅Haneline, Laura S.⋅Haneline, Laura S⋅Clapp, D. Wade and Clapp, D W
Blood, vol. 104, (no. 4), pp. 1209, 2004-08-15. | Journal Article
 
Loss of the Nf1 Tumor Suppressor Gene Decreases Fas Antigen Expression in Myeloid Cells
Hiatt, Kelly⋅Hiatt, Kelly⋅Ingram, David A⋅Ingram, David A.⋅Huddleston, Hannah⋅Huddleston, Hannah⋅Spandau, Dan F⋅Spandau, Dan F.⋅Kapur, Reuben⋅Kapur, Reuben⋅Clapp, D. W and Clapp, D. Wade
The American journal of pathology, vol. 164, (no. 4), pp. 1479, 2004-04-01. | Journal Article
 
Neurofibromatosis Type 1 (NF1), a Tumor Suppressor Gene, Is Synergistically Activated by RUNX1, C/EBPαa and ETS2 and Specifically Repressed by the T(8;21) Fusion Protein in Acute Myeloid Leukemia
Yang, Genyan⋅Khalaf, Waleed⋅Clapp, Wade D and Hiebert, Scott W
Blood, vol. 104, (no. 11), pp. 2551, 2004-11-16. | Journal Article
2003
Enforced expression of CUL-4A interferes with granulocytic differentiation and exit from the cell cycle
Li, Binghui⋅Li, Binghui⋅Yang, Feng-Chun⋅Yang, Feng Chun⋅Clapp, D Wade⋅Clapp, D. Wade⋅Chun, Kristin T and Chun, Kristin T.
Blood, vol. 101, (no. 5), pp. 1776, 2003-03-01. | Journal Article
 
Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis
Freie, Brian⋅Freie, Brian⋅Li, Xiaxin⋅Li, Xiaxin⋅Ciccone, Samantha L⋅Ciccone, Samantha L.M.⋅Nawa, Kathy⋅Nawa, Kathy⋅Cooper, Scott⋅Cooper, Scott⋅Vogelweid, Catherine M⋅Vogelweid, Catherine⋅Schantz, Laurel⋅Schantz, Laurel⋅Haneline, Laura S.⋅Haneline, Laura S⋅Orazi, Attilio⋅Orazi, Attilio⋅Broxmeyer, Hal E.⋅Broxmeyer, Hal E⋅Lee, Suk-Hee⋅Lee, Suk Hee⋅Clapp, D. Wade and Clapp, D W
Blood, vol. 102, (no. 12), pp. 4152, 2003-12-01. | Journal Article
 
Fanconi anemia type C–deficient hematopoietic stem/progenitor cells exhibit aberrant cell cycle control
Li, Xiaxin⋅Li, Xiaxin⋅Plett, P. Artur⋅Plett, P A⋅Yang, Yanzhu⋅Yang, Yanzhu⋅Hong, Ping⋅Hong, Ping⋅Freie, Brian⋅Freie, Brian⋅Srour, Edward F.⋅Srour, Edward F⋅Orschell, Christie M⋅Orschell, Christie M.⋅Clapp, D W⋅Clapp, D. Wade⋅Haneline, Laura S. and Haneline, Laura S
Blood, vol. 102, (no. 6), pp. 2084, 2003-09-15. | Journal Article
 
Retroviral-mediated expression of recombinant Fancc enhances the repopulating ability of Fancc−/−hematopoietic stem cells and decreases the risk of clonal evolution
Haneline, Laura S.⋅Haneline, Laura S⋅Li, Xiaxin⋅Li, Xiaxin⋅Ciccone, Samantha L⋅Ciccone, Samantha L.M.⋅Hong, Ping⋅Hong, Ping⋅Yang, Yanzhu⋅Yang, Yanzhu⋅Broxmeyer, Hal E.⋅Broxmeyer, Hal E⋅Lee, Suk Hee⋅Lee, Suk-Hee⋅Orazi, Attilio⋅Orazi, Attilio⋅Srour, Edward F.⋅Srour, Edward F⋅Clapp, D. W and Clapp, D. Wade
Blood, vol. 101, (no. 4), pp. 1307, 2003-02-15. | Journal Article
 
Transgenic Expression of Stromal Cell-Derived Factor-1/CXC Chemokine Ligand 12 Enhances Myeloid Progenitor Cell Survival/Antiapoptosis In Vitro in Response to Growth Factor Withdrawal and Enhances Myelopoiesis In Vivo
Broxmeyer, Hal E⋅Broxmeyer, Hal⋅Cooper, S.⋅Cooper, Scott⋅Kohli, L.⋅Kohli, Lisa⋅Hangoc, G.⋅Hangoc, Giao⋅Lee, Younghee⋅Lee, Y.⋅Mantel, Charlie⋅Mantel, Charlie R⋅Clapp, David W⋅Clapp, D.⋅Kim, Chang and Kim, Chang H
The Journal of immunology (1950), vol. 170, (no. 1), pp. 429, 20030101. | Journal Article
2002
Lymphoproliferative defects in mice lacking the expression of neurofibromin: functional and biochemical consequences of Nf1 deficiency in T-cell development and function
Ingram, David A⋅INGRAM, David A⋅Ingram, David A⋅Ingram, David A⋅Zhang, Lei⋅ZHANG, LEI⋅Zhang, Lei⋅Zhang, Lei⋅McCarthy, Jennifer⋅McCarthy, Jennifer⋅McCarthy, Jennifer⋅MCCARTHY, Jennifer⋅WENNING, Mary Jo⋅Wenning, Mary Jo⋅Wenning, Mary J⋅Wenning, Mary Jo⋅Fisher, Lucy⋅Fisher, Lucy⋅Fisher, Lucy⋅FISHER, Lucy⋅Yang, Feng Chun⋅YANG, Feng-Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Clapp, D Wade⋅Clapp, D W⋅Clapp, D. Wade⋅Clapp, D Wade⋅KAPUR, Reuben⋅Kapur, Reuben⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 100, (no. 10), pp. 3662, 2002-11-15. | Journal Article