17 Publications
2013
Regulation of Bone Marrow Angiogenesis by Osteoblasts during Bone Development and Homeostasis.
Schipani, ErnestinaWu, CollenRankin, Erinn and Giaccia, Amato J
Frontiers in endocrinology, vol. 4, pp. 85, 2013. | Journal Article
2012
VEGF-Independent Cell-Autonomous Functions of HIF-1 alpha Regulating Oxygen Consumption in Fetal Cartilage Are Critical for Chondrocyte Survival
Maes, C.Araldi, E.Haigh, K.Khatri, R.Van Looveren, R.Giaccia, AJHaigh, JJCarmeliet, G. and Schipani, Ernestina
Journal of Bone and Mineral Research, vol. 27, (no. 3), pp. 596-609, 2012. | Journal Article
 
VEGF-independent cell-autonomous functions of HIF-1α regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival.
Maes, ChristaAraldi, ElisaHaigh, KatharinaKhatri, RichaVan Looveren, RietGiaccia, Amato JHaigh, Jody JCarmeliet, Geert and Schipani, Ernestina
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol. 27, (no. 3), pp. 596-609, 2012/Mar. | Journal Article
2010
Hypoxia, HIFs and bone development.
Araldi, Elisa and Schipani, Ernestina
Bone, vol. 47, (no. 2), pp. 190-196, August 2010. | Journal Article
 
Role of HIF-1alpha in skeletal development.
Wan, ChaoShao, JinGilbert, Shawn RRiddle, Ryan CLong, FanxinJohnson, Randall SSchipani, Ernestina and Clemens, Thomas L
Annals of the New York Academy of Sciences, vol. 1192, (no. 1), pp. 322-6, 2010/Mar. | Journal Article
 
Targeted deletion of Capn4 in cells of the chondrocyte lineage impairs chondrocyte proliferation and differentiation.
Kashiwagi, AkiSchipani, ErnestinaFein, Mikaela JGreer, Peter A and Shimada, Masako
Molecular and cellular biology, vol. 30, (no. 11), pp. 2799-2810, June 2010. | Journal Article
2009
Regulation of osteogenesis-angiogenesis coupling by HIFs and VEGF.
Schipani, ErnestinaMaes, ChristaCarmeliet, Geert and Semenza, Gregg L
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol. 24, (no. 8), pp. 1347-53, 2009/Aug. | Journal Article
 
Role of hypoxia-inducible factor-1 alpha in angiogenic-osteogenic coupling
Riddle, Ryan CKhatri, RichaSchipani, Ernestina and Clemens, Thomas L
Journal of Molecular Medicine (Berlin, Germany), vol. 87, (no. 6), pp. 583-590, 2009. | Journal Article
 
Role of hypoxia-inducible factor-1alpha in angiogenic-osteogenic coupling.
Riddle, Ryan CKhatri, RichaSchipani, Ernestina and Clemens, Thomas L
Journal of molecular medicine (Berlin, Germany), vol. 87, (no. 6), pp. 583-90, 2009/Jun. | Journal Article
2008
Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes
O'Brien, Charles AO'brien, Charles APlotkin, Lilian IPlotkin, Lilian IGalli, CarloGalli, CarloGoellner, Joseph JGoellner, Joseph JGortazar, Arancha RGortazar, Arancha RAllen, Matthew RAllen, Matthew RRobling, AlexanderRobling, Alexander GBouxsein, MaryBouxsein, Mary LSchipani, ErnestinaSchipani, ErnestinaTurner, Charles HTurner, Charles HJilka, Robert LJilka, Robert LWeinstein, Robert SWeinstein, Robert SManolagas, Stavros CManolagas, Stavros CBellido, TeresitaBellido, Teresita and Jin, Dong-Yan
PloS ONE, vol. 3, (no. 8), pp. e2942, 2008. | Journal Article
 
In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation.
Shimada, MasakoGreer, Peter AMc Mahon, Andrew PBouxsein, Mary L and Schipani, Ernestina
The Journal of biological chemistry, vol. 283, (no. 30), pp. 21002-10, 2008/Jul/25. | Journal Article
2007
The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.
Wang, YingWan, ChaoDeng, LianfuLiu, XimengCao, XuemeiGilbert, Shawn RBouxsein, Mary LMonier Faugere, Marie Claude MGuldberg, Robert EGerstenfeld, Louis CHaase, Volker HJohnson, Randall SSchipani, Ernestina and Clemens, Thomas L
The Journal of clinical investigation, vol. 117, (no. 6), pp. 1616-26, 2007/Jun. | Journal Article
2004
Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development
Pfander, D.Kobayashi, T.Knight, MCZelzer, ElazarChan, Denise AOlsen, Bjorn RGiaccia, AmatoJohnson, Randall SHaase, Volker H and Schipani, Ernestina
Development, vol. 131, (no. 10), pp. 2497-2508, 2004. | Journal Article
 
VEGFA is necessary for chondrocyte survival during bone development.
Zelzer, ElazarMamluk, RoniFerrara, NapoleoneJohnson, Randall SSchipani, Ernestina and Olsen, Bjorn R
Development (Cambridge, England), vol. 131, (no. 9), pp. 2161-71, 2004/May. | Journal Article
2001
Hypoxia in cartilage: HIF-1 alpha is essential for chondrocyte growth arrest and survival
Schipani, ErnestinaRyan, HEDidrickson, S.Kobayashi, TatsuyaKnight, M. and Johnson, Randall S
Genes & Development, vol. 15, (no. 21), pp. 2865-2876, 2001. | Journal Article
 
Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival.
Schipani, ErnestinaRyan, H EDidrickson, SKobayashi, TKnight, M and Johnson, Randall S
Genes & development, vol. 15, (no. 21), pp. 2865-76, 2001/Nov/1. | Journal Article
1998
The gene responsible for pseudohypoparathyroidism type Ib is paternally imprinted and maps in four unrelated kindreds to chromosome 20q13.3.
Jüppner, HSchipani, ErnestinaBastepe, MCole, D ELawson, Margaret LMannstadt, MHendy, G NPlotkin, HKoshiyama, HKoh, TCrawford, J DOlsen, Bjorn R and Vikkula, Miikka
Proceedings of the National Academy of Sciences of the United States of America, vol. 95, (no. 20), pp. 11798-803, 1998/Sep/29. | Journal Article