120 Publications (Page 3 of 5)
2012
The presence of A beta seeds, and not age per se, is critical to the initiation of A beta deposition in the brain
Hamaguchi, Tsuyoshi⋅Eisele, Yvonne S⋅Varvel, Nicholas H⋅Lamb, Bruce T⋅Walker, Lary C and Jucker, Mathias
Acta Neuropathologica, vol. 123, (no. 1), pp. 31-37, 2012. | Journal Article
 
The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain.
Hamaguchi, Tsuyoshi⋅Eisele, Yvonne S⋅Varvel, Nicholas H⋅Lamb, Bruce T⋅Walker, Lary and Jucker, Mathias
Acta neuropathologica, vol. 123, (no. 1), pp. 31-7, 2012/Jan. | Journal Article
 
The Psen1‐L166P‐knock‐in mutation leads to amyloid deposition in human wild‐type amyloid precursor protein YAC transgenic mice
Vidal, Ruben⋅Vidal, Ruben G⋅Sammeta, Neeraja⋅Sammeta, Neeraja⋅Garringer, Holly J⋅Garringer, Holly J⋅Sambamurti, Kumar⋅Sambamurti, Kumar⋅Miravalle, Leticia⋅Miravalle, Leticia⋅Lamb, Bruce T⋅Lamb, Bruce T⋅Ghetti, Bernardino and Ghetti, Bernardino
The FASEB Journal, vol. 26, (no. 7), pp. 2910, July 2012. | Journal Article
 
The roles of fractalkine signaling in neurodegenerative disease.
Lamb, Bruce
Molecular neurodegeneration, vol. 7 Suppl 1, pp. L21, February 7, 2012. | Journal Article
2011
Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain.
Vogt, D L⋅Thomas, D⋅Galvan, V⋅Bredesen, D E⋅Lamb, Bruce T and Pimplikar, S W
Neurobiology of aging, vol. 32, (no. 9), pp. 1725-9, 2011/Sep. | Journal Article
 
Right sizing funding for Alzheimer's disease.
Golde, Todd E⋅Lamb, Bruce T and Galasko, Douglas
Alzheimer's research & therapy, vol. 3, (no. 3), pp. 17, 2011. | Journal Article
2010
CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.
Lee, Sungho⋅Varvel, Nicholas H⋅Konerth, Megan E⋅Xu, Guixiang⋅Cardona, Astrid E⋅Ransohoff, Richard M and Lamb, Bruce T
The American journal of pathology, vol. 177, (no. 5), pp. 2549-62, 2010/Nov. | Journal Article
 
Photoreceptor degeneration, azoospermia, leukoencephalopathy, and abnormal RPE cell function in mice expressing an early stop mutation in CLCN2.
Edwards, Malia M⋅Marín de Evsikova, Caralina⋅Collin, Gayle B⋅Gifford, Elaine⋅Wu, Jiang⋅Hicks, Wanda L⋅Whiting, Carrie⋅Varvel, Nicholas H⋅Maphis, Nicole⋅Lamb, Bruce T⋅Naggert, Jurgen K⋅Nishina, Patsy and Peachey, Neal S
Investigative ophthalmology & visual science, vol. 51, (no. 6), pp. 3264-72, 2010/Jun. | Journal Article
 
Regulation of tau pathology by the microglial fractalkine receptor.
Bhaskar, Kiran⋅Konerth, Megan⋅Kokiko-Cochran, Olga N⋅Cardona, Astrid E⋅Ransohoff, Richard M and Lamb, Bruce T
Neuron, vol. 68, (no. 1), pp. 19-31, 2010/Oct/6. | Journal Article
 
S4‐03‐04: The Opposing Roles of Fractalkine Signaling in Alzheimer's Disease Pathogenesis
Lamb, Bruce T⋅Bhaskar, Kiran⋅Lee, Sungho⋅Varvel, Nicholas H⋅Konerth, Megan E⋅Kokiko-Cochran, Olga N⋅Cardona, Astrid E and Ransohoff, Richard M
Alzheimer's & Dementia, vol. 6, pp. e14, July 2010. | Journal Article
2009
Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain
Ghosal, Kaushik⋅Vogt, Daniel L⋅Liang, Man⋅Shen, Yong⋅Lamb, Bruce and Pimplikar, Sanjay W
Proceedings of the National Academy of Sciences, USA, vol. 106, (no. 43), pp. 18367-18372, 2009. | Journal Article
 
Nitric oxide as an initiator of brain lesions during the development of Alzheimer disease.
Aliev, Gjumrakch⋅Palacios, Hector H⋅Lipsitt, Amanda E⋅Fischbach, Kathryn⋅Lamb, Bruce T⋅Obrenovich, Mark E⋅Morales, Ludis⋅Gasimov, Eldar and Bragin, Valentin
Neurotoxicity research, vol. 16, (no. 3), pp. 293-305, 2009/Oct. | Journal Article
 
NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease.
Varvel, Nicholas H⋅Varvel, Nicholas H⋅Bhaskar, Kiran⋅Bhaskar, Kiran⋅Kounnas, Maria Z⋅Kounnas, Maria Z⋅Wagner, Steven L⋅Wagner, Steven L⋅Yang, Yan⋅Yang, Yan⋅Lamb, Bruce T⋅Lamb, Bruce T⋅Herrup, Karl and Herrup, Karl
The Journal of clinical investigation, vol. 119, (no. 12), pp. 3692-702, 2009/Dec. | Journal Article
 
Pathology associated memory deficits in Swedish mutant genome-based amyloid precursor protein transgenic mice.
Hock, Brian J⋅Hock, B.J.⋅Lattal, K.M.⋅Lattal, K M⋅Kulnane, L.S.⋅Kulnane, Laura S⋅Abel, T.⋅Abel, Ted⋅Lamb, B.T. and Lamb, Bruce T
Current aging science, vol. 2, (no. 3), pp. 205-13, 2009/Dec. | Journal Article
 
The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites
Muresan, Virgil⋅Muresan, Virgil⋅Varvel, Nicholas H⋅Varvel, Nicholas H⋅Lamb, Bruce T⋅Lamb, Bruce T⋅Muresan, Zoia and Muresan, Zoia
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 29, (no. 11), pp. 3578, 2009-Mar-18. | Journal Article
 
The PI3K-Akt-mTOR pathway regulates Abeta oligomer induced neuronal cell cycle events.
Bhaskar, Kiran⋅Miller, Megan⋅Chludzinski, Alexandra⋅Herrup, Karl⋅Zagorski, Michael and Lamb, Bruce T
Molecular neurodegeneration, vol. 4, pp. 14, 2009. | Journal Article
2008
Abeta oligomers induce neuronal cell cycle events in Alzheimer's disease.
Varvel, Nicholas H⋅Bhaskar, Kiran⋅Patil, Anita R⋅Pimplikar, Sanjay W⋅Herrup, Karl and Lamb, Bruce T
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 28, (no. 43), pp. 10786-93, 2008/Oct/22. | Journal Article
 
Genetic loci modulating amyloid-beta levels in a mouse model of Alzheimer's disease.
Ryman, Davis⋅Gao, Yuan and Lamb, Bruce T
Neurobiology of aging, vol. 29, (no. 8), pp. 1190-8, 2008/Aug. | Journal Article
2007
Genetic loci modulating amyloid-beta levels in a mouse model of Alzheimer's disease
Ryman, Davis⋅Gao, Yuan and Lamb, Bruce
Neurobiology of Aging, vol. 29, (no. 8), pp. 1198, 2007. | Journal Article
 
Spatial and temporal control of age-related APP processing in genomic-based beta -secretase transgenic mice
Chiocco, Matthew J and Lamb, Bruce
Neurobiology of Aging, vol. 28, (no. 1), pp. 75-84, 2007. | Journal Article
 
Spatial and temporal control of age-related APP processing in genomic-based beta-secretase transgenic mice.
Chiocco, Matthew J and Lamb, Bruce T
Neurobiology of aging, vol. 28, (no. 1), pp. 75-84, January 2007. | Journal Article
2006
Ectopic Cell Cycle Events Link Human Alzheimer's Disease and Amyloid Precursor Protein Transgenic Mouse Models
Yang, Yan⋅Varvel, Nicholas H⋅Lamb, Bruce and Herrup, Karl
Journal of Neuroscience, vol. 26, (no. 3), pp. 775-784, 2006. | Journal Article
 
Genetic and Environmental Modifiers of Alzheimer's Disease Phenotypes in the Mouse
Ryman, Davis and Lamb, Bruce
Current Alzheimer Research, vol. 3, (no. 5), pp. 465-473, 2006. | Journal Article
 
Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration
Salehi, Ahmad⋅Delcroix, Jean-Dominique⋅Belichenko, Pavel V⋅Zhan, Ke⋅Wu, Chengbiao⋅Valletta, Janice S⋅Takimoto-Kimura, Ryoko⋅Kleschevnikov, Alexander M⋅Sambamurti, Kumar⋅Chung, Peter P⋅Xia, Weiming⋅Villar, Angela⋅Campbell, William A⋅Kulnane, Laura S⋅Nixon, Ralph A⋅Lamb, Bruce⋅Epstein, Charles J⋅Stokin, Gorazd B⋅Goldstein, Lawrence and Mobley, William C
Neuron, vol. 51, (no. 1), pp. 29-42, 2006. | Journal Article
 
P1–123: Modifiers of Alzheimer's disease phenotypes in the mouse
Lamb, Bruce T⋅Ryman, Davis C⋅Schrump, Stephanie and Varvel, Nicholas
Alzheimer's & Dementia, vol. 2, pp. S132, July 2006. | Journal Article