120 Publications (Page 2 of 5)
2018
S2‐02‐01: NEW IN VIVO MODELS FOR ALZHEIMER'S DISEASE: MODEL‐ADLamb, Bruce TAlzheimer's & Dementia, vol. 14, (no. 7S_Part_11), pp. P601, July 2018.
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The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer’s diseaseCheng-Hathaway, Paul J⋅Cheng-Hathaway, Paul J⋅Cheng-Hathaway, Paul J⋅Reed-Geaghan, Erin G⋅Reed-Geaghan, Erin G⋅Reed-Geaghan, Erin G⋅Jay, Taylor R⋅Jay, Taylor R⋅Jay, Taylor R⋅Casali, Brad T⋅Casali, Brad T⋅Casali, Brad T⋅Bemiller, Shane M⋅Bemiller, Shane M⋅Bemiller, Shane M⋅Puntambekar, Shweta S⋅Puntambekar, Shweta S⋅Puntambekar, Shweta S⋅von Saucken, Victoria E⋅von Saucken, Victoria E⋅von Saucken, Victoria E⋅Williams, Roxanne Y⋅Williams, Roxanne Y⋅Williams, Roxanne Y⋅Karlo, J. Colleen⋅Karlo, J Colleen⋅Karlo, J. Colleen⋅Moutinho, Miguel⋅Moutinho, Miguel⋅Moutinho, Miguel⋅Xu, Guixiang⋅Xu, Guixiang⋅Xu, Guixiang⋅Ransohoff, Richard M⋅Ransohoff, Richard M⋅Ransohoff, Richard M⋅Lamb, Bruce T⋅Lamb, Bruce T⋅Lamb, Bruce T⋅Landreth, Gary E⋅Landreth, Gary E and Landreth, Gary EMolecular Neurodegeneration, vol. 13, (no. 1), pp. 12, 2018-12-00.
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Traumatic Brain Injury in hTau Model Mice: Enhanced Acute Macrophage Response and Altered Long-Term RecoveryKokiko-Cochran, Olga N⋅Saber, Maha⋅Puntambekar, Shweta⋅Bemiller, Shane M⋅Katsumoto, Atsuko⋅Lee, Yu-Shang⋅Bhaskar, Kiran⋅Ransohoff, Richard M and Lamb, Bruce TJournal of Neurotrauma, vol. 35, (no. 1), pp. 84, 2018-01-01.
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2017
CONCUSSION, MICROVASCULAR INJURY, AND EARLY TAUOPATHY IN YOUNG ATHLETES AFTER IMPACT HEAD INJURY AND AN IMPACT CONCUSSION MOUSE MODEFisher, Andrew M⋅Tagge, Chad A⋅Minaeva, Olga⋅Gaudreau, Amanda⋅Moncaster, Juliet A⋅Zhang, Xiao-Lei⋅Wojnarowicz, Mark W⋅Casey, Noel F⋅Lu, Haiyan⋅Kokiko-Cochran, Olga⋅Saman, Sudad⋅Ericsson, Maria⋅Onos, Kristen⋅Veksler, Ronel⋅Senatorov, Vlad⋅Kondo, Asami⋅Zhou, Xiao⋅Miry, Omid⋅Vose, Linnea R⋅Gopaul, Katisha⋅Upreti, Chirag⋅Nowinski, Christopher⋅Cantu, Robert⋅Alvarez, Victor E⋅Hua, Ning⋅Tripodis, Yorghos⋅Anderson, Andrew⋅Howell, Gareth⋅Kaufer, Daniela⋅Hall, Garth F⋅Lu, Kun Ping⋅Ransohoff, Richard⋅Cleveland, Robin O⋅Kowall, Neil W⋅Huber, Bertrand R⋅Stein, Thor D⋅Lamb, Bruce T⋅Moss, William C⋅Friedman, Alon⋅Stanton, Patric K⋅McKee, Ann C and Goldstein, Lee EAlzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 13, (no. 7), pp. P984, July 2017.
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Disease progression-dependent effects of TREM2 deficiency in a mouse model of Alzheimer’s diseaseJay, T. R.⋅Hirsch, A. M.⋅Broihier, M. L.⋅Miller, C. M.⋅Neilson, L. E.⋅Ransohoff, R. M.⋅Lamb, B. T. and Landreth, G. E.Journal of Neuroscience.
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Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer’s DiseaseJay, Taylor R⋅Jay, Taylor R.⋅Hirsch, Anna M.⋅Hirsch, Anna M⋅Broihier, Margaret L⋅Broihier, Margaret L.⋅Miller, Crystal M.⋅Miller, Crystal M⋅Neilson, Lee E⋅Neilson, Lee E.⋅Ransohoff, Richard M⋅Ransohoff, Richard M.⋅Lamb, Bruce T.⋅Lamb, Bruce T⋅Landreth, Gary E. and Landreth, Gary EThe Journal of Neuroscience, vol. 37, pp. 637–647.
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INFLAMMATORY AND BLOOD BRAIN BARRIER BREAKDOWN PROTEIN LEVELS CORRELATE WITH NEURODEGENERATION BIOMARKERS IN THE MILD COGNITIVE IMPAIRMENT STAGE OF ALZHEIMER’S DISEASEPillai, Jagan A⋅Lamb, Bruce T⋅Bekris, Lynn M⋅Khrestian, Maria⋅Bena, James⋅Rao, Stephen and Leverenz, James BAlzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 13, (no. 7), pp. P230, July 2017.
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TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathyBemiller, Shane M⋅Bemiller, Shane M⋅McCray, Tyler J⋅McCray, Tyler J⋅Allan, Kevin⋅Allan, Kevin⋅Formica, Shane V⋅Formica, Shane V⋅Xu, Guixiang⋅Xu, Guixiang⋅Wilson, Gina⋅Wilson, Gina⋅Kokiko-Cochran, Olga N⋅Kokiko-Cochran, Olga N⋅Crish, Samuel D⋅Crish, Samuel D⋅Lasagna-Reeves, Cristian A⋅Lasagna-Reeves, Cristian A⋅Ransohoff, Richard M⋅Ransohoff, Richard M⋅Landreth, Gary E⋅Landreth, Gary E⋅Lamb, Bruce T and Lamb, Bruce TMolecular neurodegeneration, vol. 12, (no. 1), pp. 74, 2017-10-16.
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Triggering Receptor Expressed on Myeloid Cells 2 Deficiency Alters Acute Macrophage Distribution and Improves Recovery after Traumatic Brain InjurySaber, Maha⋅Saber, Maha⋅Kokiko-Cochran, Olga⋅Kokiko-Cochran, Olga⋅Puntambekar, Shweta S⋅Puntambekar, Shweta S⋅Lathia, Justin D⋅Lathia, Justin D⋅Lamb, Bruce T and Lamb, Bruce TJournal of Neurotrauma, vol. 34, (no. 2), pp. 435, 2017-01-15.
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Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau PathologyMaphis, Nicole M⋅Maphis, Nicole M⋅Jiang, Shanya⋅Jiang, Shanya⋅Binder, Jessica⋅Binder, Jessica⋅Wright, Carrie⋅Wright, Carrie⋅Gopalan, Banu⋅Gopalan, Banu⋅Lamb, Bruce T⋅Lamb, Bruce T⋅Bhaskar, Kiran and Bhaskar, KiranFrontiers in molecular neuroscience, vol. 10, pp. 69, 2017-00-00.
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2016
Altered Neuroinflammation and Behavior after Traumatic Brain Injury in a Mouse Model of Alzheimer's DiseaseKokiko-Cochran, Olga⋅Ransohoff, Lena⋅Veenstra, Mike⋅Lee, Sungho⋅Saber, Maha⋅Sikora, Matt⋅Teknipp, Ryan⋅Xu, Guixiang⋅Bemiller, Shane⋅Wilson, Gina⋅Crish, Samuel⋅Bhaskar, Kiran⋅Lee, Yu-Shang⋅Ransohoff, Richard M and Lamb, Bruce TJournal of Neurotrauma, vol. 33, (no. 7), pp. 640, 2016-04-01.
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EARLY CHRONIC TRAUMATIC ENCEPHALOPATHY IN YOUNG ATHLETES AFTER CONCUSSIVE CLOSED-HEAD IMPACT INJURY AND MOUSE MODEL OF IMPACT CONCUSSIONGoldstein, Lee⋅Tagge, Chad⋅Fisher, Andrew⋅Minaeva, Olga⋅Gaudreau, Amanda⋅Zhang, Xiao-Lei⋅Upreti, Chirag⋅Ericsson, Maria⋅Wojnarowicz, Mark⋅Casey, Noel⋅Moncaster, Juliet⋅Nowinski, Christopher⋅Cantu, Robert⋅Saman, Sudad⋅Hall, Garth⋅Alvarez, Victor⋅Kondo, Asami⋅Anderson, Andy⋅Veksler, Ronel⋅Onos, Kristen⋅Lu, Haiyan⋅Senatorov, Vlad⋅Huber, Bertrand⋅Stein, Thor⋅Tripodis, Yorghos⋅Kaufer, Daniela⋅Lu, Kun⋅Cleveland, Robin⋅Howell, Gareth⋅Friedman, Alon⋅Ransohoff, Richard⋅Lamb, Bruce⋅Moss, William⋅Stanton, Patric and McKee, AnnAlzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 12, (no. 7), pp. P629, 2016.
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Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathologyNicole Maphis⋅Maphis, Nicole⋅Maphis, N.⋅Shanya Jiang⋅Jiang, Shanya⋅Jiang, S.⋅Xu, Guixiang⋅Xu, G.⋅Guixiang Xu⋅Kokiko-Cochran, O.N.⋅Olga N Kokiko-Cochran⋅Kokiko-Cochran, Olga N⋅Roy, Saktimayee M⋅Saktimayee M Roy⋅Roy, S.M.⋅Linda J Van Eldik⋅Van Eldik, L.J.⋅Van Eldik, Linda J⋅D Martin Watterson⋅Watterson, D.M.⋅Watterson, D Martin⋅Bruce T Lamb⋅Lamb, B.T.⋅Lamb, Bruce T⋅Bhaskar, Kiran⋅Bhaskar, K. and Kiran BhaskarAlzheimer's research & therapy, vol. 8, (no. 1), pp. 54, 2016-12-15.
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THE R47H TREM2 VARIANT MODIFIES ALZHEIMER'S DISEASE PATHOLOGY AND NEUROINFLAMMATION IN A NOVEL KNOCK-IN MOUSE MODELCheng-Hathaway, Paul⋅Cheng-Hathaway, Paul⋅Jay, Taylor⋅Jay, Taylor⋅Reed, Erin⋅Reed, Erin⋅Bemiller, Shane⋅Bemiller, Shane⋅Puntambekar, Shweta⋅Puntambekar, Shweta⋅Xu, Guixiang⋅Xu, Guixiang⋅Carlo, Colleen⋅Carlo, Colleen⋅Ransohoff, Richard⋅Ransohoff, Richard⋅Landreth, Gary⋅Landreth, Gary⋅Lamb, Bruce and Lamb, BruceAlzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 12, (no. 7), pp. P243, 2016.
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TREM2 CLEARANCE OF AMYLOID: PERIPHERAL VS. CNS-DERIVED CELLSLamb, BruceAlzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 12, (no. 7), pp. P214, 2016.
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2015
Human tau expression reduces adult neurogenesis in a mouse model of tauopathyKomuro, Yutaro⋅Komuro, Yutaro⋅Xu, Guixiang⋅Xu, Guixiang⋅Bhaskar, Kiran⋅Bhaskar, Kiran⋅Lamb, Bruce T and Lamb, BruceNeurobiology of Aging, vol. 36, (no. 6), pp. 2042, 2015.
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Loss of tau rescues inflammation-mediated neurodegenerationMaphis, Nicole⋅Maphis, Nicole⋅Maphis, Nicole⋅Xu, Guixiang⋅Xu, Guixiang⋅Xu, Guixiang⋅Kokiko-Cochran, Olga N⋅Kokiko-Cochran, Olga N⋅Kokiko-Cochran, Olga N⋅Cardona, Astrid E⋅Cardona, Astrid E⋅Cardona, Astrid E⋅Ransohoff, Richard M⋅Ransohoff, Richard M⋅Ransohoff, Richard M⋅Lamb, Bruce T⋅Lamb, Bruce T⋅Lamb, Bruce T⋅Bhaskar, Kiran⋅Bhaskar, Kiran and Bhaskar, KiranFrontiers in Neuroscience, vol. 9, pp. 196, 2015-06-03.
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Nuclear receptors license phagocytosis by trem2+ myeloid cells in mouse models of Alzheimer's disease.Savage, Julie C⋅Jay, Taylor⋅Goduni, Elanda⋅Quigley, Caitlin⋅Mariani, Monica M⋅Malm, Tarja⋅Ransohoff, Richard M⋅Lamb, Bruce T and Landreth, Gary EThe Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 35, (no. 16), pp. 6532-6543, April 22, 2015.
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TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.Jay, Taylor R⋅Miller, Crystal M⋅Cheng, Paul J⋅Graham, Leah C⋅Bemiller, Shane⋅Broihier, Margaret L⋅Xu, Guixiang⋅Margevicius, Daniel⋅Karlo, J Colleen⋅Sousa, Gregory L⋅Cotleur, Anne C⋅Butovsky, Oleg⋅Bekris, Lynn⋅Staugaitis, Susan M⋅Leverenz, James B⋅Pimplikar, Sanjay W⋅Landreth, Gary E⋅Howell, Gareth R⋅Ransohoff, Richard M and Lamb, Bruce TThe Journal of experimental medicine, vol. 212, (no. 3), pp. 287-295, March 9, 2015.
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Vascular contributions to cognitive impairment and dementia including Alzheimer's diseaseSnyder, Heather M⋅Snyder, Heather⋅Corriveau, Roderick⋅Corriveau, Roderick A⋅Craft, Suzanne⋅Craft, Suzanne⋅Faber, James⋅Faber, James E⋅Greenberg, Steven M⋅Greenberg, Steven⋅Knopman, David⋅Knopman, David⋅Lamb, Bruce⋅Lamb, Bruce T⋅Montine, Thomas J⋅Montine, Thomas⋅Nedergaard, Maiken⋅Nedergaard, Maiken⋅Schaffer, Chris⋅Schaffer, Chris B⋅Schneider, Julie A⋅Schneider, Julie⋅Wellington, Cheryl⋅Wellington, Cheryl⋅Wilcock, Donna M⋅Wilcock, Donna⋅Zipfel, Gregory J⋅Zipfel, Gregory⋅Zlokovic, Berislav⋅Zlokovic, Berislav⋅Bain, Lisa J⋅Bain, Lisa⋅Bosetti, Francesca⋅Bosetti, Francesca⋅Galis, Zorina S⋅Galis, Zorina⋅Koroshetz, Walter⋅Koroshetz, Walter⋅Carrillo, Maria C and Carrillo, MariaAlzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 11, (no. 6), pp. 717, 2015.
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2014
10Bhaskar, Kiran⋅Maphis, Nicole⋅Kang, Zhizen⋅Li, Xiaoxia and Lamb, BruceCytokine, vol. 70, (no. 1), pp. 30, 20141101.
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Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events.Bhaskar, Kiran⋅Maphis, Nicole⋅Xu, Guixiang⋅Varvel, Nicholas H⋅Kokiko-Cochran, Olga N⋅Weick, Jason⋅Staugaitis, Susan M⋅Cardona, Astrid E⋅Ransohoff, Richard M⋅Herrup, Karl and Lamb, Bruce TNeurobiology of disease, vol. 62, pp. 273-85, 2014/Feb.
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Opposing effects of membrane-anchored CX3CL1 on amyloid and tau pathologies via the p38 MAPK pathway.Lee, Sungho⋅Lee, Sungho⋅Xu, Guixiang⋅Xu, Guixiang⋅Jay, Taylor R⋅Jay, Taylor R⋅Bhatta, Sabina⋅Bhatta, Sabina⋅Kim, Ki-Wook⋅Kim, Ki-Wook⋅Jung, Steffen⋅Jung, Steffen⋅Landreth, Gary E⋅Landreth, Gary E⋅Ransohoff, Richard M⋅Ransohoff, Richard M⋅Lamb, Bruce T and Lamb, Bruce TThe Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 34, (no. 37), pp. 12538-12546, September 10, 2014.
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2012
Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's diseaseWilkinson, Brandy L⋅Wilkinson, Brandy⋅Cramer, Paige⋅Cramer, Paige E⋅Varvel, Nicholas⋅Varvel, Nicholas H⋅Reed-Geaghan, Erin⋅Reed-Geaghan, Erin⋅Jiang, Qingguang⋅Jiang, Qingguang⋅Szabo, Alison⋅Szabo, Alison⋅Herrup, Karl⋅Herrup, Karl⋅Lamb, Bruce⋅Lamb, Bruce⋅Landreth, Gary E and Landreth, GaryNeurobiology of Aging, vol. 33, (no. 1), pp. 197.e21-197.e32, 2012.
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Loss of interleukin receptor-associated kinase 4 signaling suppresses amyloid pathology and alters microglial phenotype in a mouse model of Alzheimer's disease.Cameron, Brent⋅Cameron, Brent⋅Tse, Wayne⋅Tse, Wayne⋅Lamb, Raza⋅Lamb, Raza⋅Li, Xiaoxia⋅Li, Xiaoxia⋅Lamb, Bruce T⋅Lamb, Bruce T⋅Landreth, Gary E and Landreth, Gary EThe Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 32, (no. 43), pp. 15112-23, 2012/Oct/24.
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