86 Publications (Page 1 of 4)
2022
Abstract 13223: Calcium/Calmodulin-Dependent Protein Kinase II Decreases KCNH2-Related Current During Sustained Adrenergic Receptor Stimulation
Amarh, Enoch⋅Amarh, Enoch⋅Amarh, Enoch⋅Amarh, Enoch⋅Assiri, Abdullah A⋅Assiri, Abdullah A⋅Assiri, Abdullah A⋅Assiri, Abdullah A⋅Sahoo, Firoj K⋅Sahoo, Firoj K⋅Sahoo, Firoj K⋅Sahoo, Firoj K⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Tisdale, James E⋅Tisdale, James E⋅Tisdale, James E⋅Tisdale, James E⋅Skaar, Todd C⋅Skaar, Todd C⋅Skaar, Todd C⋅Skaar, Todd C⋅Overholser, Brian R⋅Overholser, Brian R⋅Overholser, Brian R and Overholser, Brian R
Circulation (New York, N.Y.), vol. 146, (no. Suppl_1), pp. A13223, 2022-11-08. | Journal Article
 
CaMKII Inhibition Attenuates Distinct Gain-of-Function Effects Produced by Mutant Nav1.6 Channels and Reduces Neuronal Excitability
Zybura, Agnes S.⋅Sahoo, Firoj K.⋅Hudmon, Andy and Cummins, Theodore R.
Cells (Basel, Switzerland), vol. 11, (no. 13), pp. 2108, 20220704. | Journal Article
 
Structural characterization of tyrosine kinase substrate binding and array-based functional peptide screening of Src kinase
Xie, Dan⋅Xie, Dan⋅Xie, Dan⋅Sun, Yixing⋅Sun, Yixing⋅Sun, Yixing⋅Krusemark, Casey J.⋅Krusemark, Casey J.⋅Krusemark, Casey J.⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Post, Carol B.⋅Post, Carol B. and Post, Carol B.
Biophysical journal, vol. 121, (no. 3), pp. 452a, 2022-02-11. | Journal Article
2021
Distinctive Properties and Powerful Neuromodulation of Nav1.6 Sodium Channels Regulates Neuronal Excitability
Zybura, Agnes⋅Hudmon, Andy and Cummins, Theodore R.
Cells (Basel, Switzerland), vol. 10, (no. 7), pp. 1595, 20210625. | Journal Article
 
Regulation of serotonin transport by geranylgeranyl transferase and Ca2+/calmodulin‐dependent protein kinase II
Deveau, Carmen⋅Hudmon, Andy and Yamamoto, Bryan
The FASEB journal, vol. 35, pp. n/a, May 2021. | Journal Article
2020
Calmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5
Wang, Zizun⋅Vermij, Sarah H.⋅Sottas, Valentin⋅Shestak, Anna⋅Ross-Kaschitza, Daniela⋅Zaklyazminskaya, Elena V.⋅Hudmon, Andy⋅Pitt, Geoffrey S.⋅Rougier, Jean-Sébastien and Abriel, Hugues
Channels (Austin, Tex.), vol. 14, (no. 1), pp. 286, 2020-01-01. | Journal Article
 
CaMKII enhances voltage-gated sodium channel Nav1.6 activity and neuronal excitability
Zybura, Agnes S.⋅Baucum, Anthony J.⋅Rush, Anthony M.⋅Cummins, Theodore R. and Hudmon, Andy
The Journal of biological chemistry, vol. 295, (no. 33), pp. 11865, 2020-08-14. | Journal Article
 
Neurohormonal Regulation of IKs in Heart Failure: Implications for Ventricular Arrhythmogenesis and Sudden Cardiac Death.
Shugg, Tyler⋅Shugg, Tyler⋅Hudmon, Andy⋅Hudmon, Andy⋅Overholser, Brian R and Overholser, Brian R
Journal of the American Heart Association, vol. 9, (no. 18), pp. e016900, September 15, 2020. | Journal Article
2019
Assemblies of calcium/calmodulin-dependent kinase II with actin and their dynamic regulation by calmodulin in dendritic spines.
Wang, Qian⋅Wang, Qian⋅Chen, Mingchen⋅Chen, Mingchen⋅Schafer, Nicholas P⋅Schafer, Nicholas P⋅Bueno, Carlos⋅Bueno, Carlos⋅Song, Sarah S⋅Song, Sarah S⋅Hudmon, Andy⋅Hudmon, Andy⋅Wolynes, Peter G⋅Wolynes, Peter G⋅Waxham, M Neal⋅Waxham, M Neal⋅Cheung, Margaret S and Cheung, Margaret S
Proceedings of the National Academy of Sciences of the United States of America, August 27, 2019. | Journal Article
2018
Abstract 16102: Calcium/Calmodulin-Dependent Protein Kinase II Phosphorylation of KCNQ1 S484 Disrupts the Interaction Between KCNQ1 and KCNE1 Subunits
Shugg, Tyler⋅Shugg, Tyler⋅Shugg, Tyler⋅Shugg, Tyler⋅Dunn, Kenneth⋅Dunn, Kenneth⋅Dunn, Kenneth⋅Dunn, Kenneth⋅Cummins, Theodore⋅Cummins, Theodore⋅Cummins, Theodore⋅Cummins, Theodore⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Overholser, Brian⋅Overholser, Brian⋅Overholser, Brian and Overholser, Brian
Circulation (New York, N.Y.), vol. 138, (no. Suppl_1 Suppl 1), pp. A16102, 2018-November-6. | Journal Article
 
Calcium/calmodulin-dependent protein kinase II regulation of I Ks during sustained β-adrenergic receptor stimulation
Shugg, Tyler⋅Shugg, Tyler⋅Shugg, Tyler⋅Shugg, Tyler⋅Johnson, Derrick E⋅Johnson, Derrick⋅Johnson, Derrick E⋅Johnson, Derrick E⋅Shao, Minghai⋅Shao, Minghai⋅Shao, Minghai⋅Shao, Minghai⋅Lai, Xianyin⋅Lai, Xianyin⋅Lai, Xianyin⋅Lai, Xianyin⋅Witzmann, Frank⋅Witzmann, Frank⋅Witzmann, Frank⋅Witzmann, Frank⋅Cummins, Theodore R⋅Cummins, Theodore R⋅Cummins, Theodore R⋅Cummins, Theodore⋅Rubart-Von-der Lohe, Michael⋅Rubart-Von-der Lohe, Michael⋅Rubart-Von-der Lohe, Michael⋅Rubart-Von-der Lohe, Michael⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Overholser, Brian⋅Overholser, Brian R⋅Overholser, Brian R and Overholser, Brian R
Heart rhythm, vol. 15, (no. 6), pp. 895, 2018-06-00. | Journal Article
 
Disruption of nNOS-NOS1AP protein-protein interactions suppresses neuropathic pain in mice.
Lee, Wan-Hung⋅Li, Li-Li⋅Chawla, Aarti⋅Hudmon, Andy⋅Lai, Yvonne Y⋅Courtney, Michael J and Hohmann, Andrea G
Pain, vol. 159, (no. 5), pp. 849-863, May 2018. | Journal Article
 
Disruption of nNOS–NOS1AP protein–protein interactions suppresses neuropathic pain in mice
Lee, Wan-Hung⋅Lee, Wan-Hung⋅Lee, Wan-Hung⋅Lee, Wan-Hung⋅Li, Li-Li⋅Li, Li-Li⋅Li, Li-Li⋅Li, Li-Li⋅Chawla, Aarti⋅Chawla, Aarti⋅Chawla, Aarti⋅Chawla, Aarti⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Courtney, Michael J⋅Courtney, Michael J⋅Courtney, Michael J⋅Courtney, Michael J⋅Hohmann, Andrea G⋅Hohmann, Andrea G⋅Hohmann, Andrea G and Hohmann, Andrea G
Pain (Amsterdam), vol. 159, (no. 5), pp. 863, 2018-May. | Journal Article
2017
Small molecules inhibit STAT3 activation, autophagy, and cancer cell anchorage-independent growth.
Zhou, Donghui⋅Zhou, Donghui⋅Zhou, Donghui⋅Springer, Maya Z⋅Springer, Maya Z⋅Springer, Maya Z⋅Xu, David⋅Xu, David⋅Xu, David⋅Liu, Degang⋅Liu, Degang⋅Liu, Degang⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Macleod, Kay F⋅Macleod, Kay F⋅Macleod, Kay F⋅Meroueh, Samy O⋅Meroueh, Samy O and Meroueh, Samy O
Bioorganic & medicinal chemistry, vol. 25, (no. 12), pp. 2995-3005, June 15, 2017. | Journal Article
 
Structure-Based Target-Specific Screening Leads to Small-Molecule CaMKIIInhibitors.
Xu, David⋅Xu, David⋅Xu, David⋅Li, Liwei⋅Li, Liwei⋅Li, Liwei⋅Zhou, Donghui⋅Zhou, Donghui⋅Zhou, Donghui⋅Liu, Degang⋅Liu, Degang⋅Liu, Degang⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Meroueh, Samy O⋅Meroueh, Samy and Meroueh, Samy O
ChemMedChem, March 29, 2017. | Journal Article
2016
Abstract 20459: Calcium/Calmodulin-Dependent Protein Kinase II Regulates KCNQ1 to Reduce the Slow Component of the Delayed Rectifier Potassium Current, IKs
Shugg, Tyler⋅Shugg, Tyler⋅Shugg, Tyler⋅Shao, Minghai⋅Shao, Minghai⋅Shao, Minghai⋅Chawla, Aarti⋅Chawla, Aarti⋅Chawla, Aarti⋅Rubart-von der Lohe, Michael⋅Rubart-von der Lohe, Michael⋅Rubart-von der Lohe, Michael⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Overholser, Brian⋅Overholser, Brian and Overholser, Brian
Circulation (New York, N.Y.), vol. 134, (no. Suppl_1 Suppl 1), pp. A20459, 2016-November-11. | Journal Article
 
Cardiac sodium channel palmitoylation regulates channel availability and myocyte excitability with implications for arrhythmia generation.
Pei, Zifan⋅Pei, Zifan⋅Pei, Zifan⋅Xiao, Yucheng⋅Xiao, Yucheng⋅Xiao, Yucheng⋅Meng, Jingwei⋅Meng, Jingwei⋅Meng, Jingwei⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Cummins, Theodore R⋅Cummins, Theodore R and Cummins, Theodore R
Nature communications, vol. 7, pp. 12035, June 23, 2016. | Journal Article
 
Constitutive Regulation of the Glutamate/Aspartate Transporter EAAT1 by Calcium/Calmodulin-Dependent Protein Kinase II.
Chawla, Aarti R⋅Chawla, Aarti R⋅Johnson, Derrick E⋅Johnson, Derrick E⋅Zybura, Agnes S⋅Zybura, Agnes S⋅Leeds, Benjamin P⋅Leeds, Benjamin P⋅Nelson, Ross M⋅Nelson, Ross M⋅Hudmon, Andy and Hudmon, Andy
Journal of neurochemistry, November 27, 2016. | Journal Article
 
Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A.
Malty, Ramy Habashy⋅Malty, Ramy Habashy⋅Hudmon, Andy⋅Hudmon, Andy⋅Fehrenbacher, Jill C⋅Fehrenbacher, Jill C⋅Vasko, Michael R and Vasko, Michael R
Journal of neuroinflammation, vol. 13, (no. 1), pp. 181, July 11, 2016. | Journal Article
 
Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling.
Zhou, Chaoming⋅Zhou, Chaoming⋅Zhou, Chaoming⋅Ramaswamy, Swarna S⋅Ramaswamy, Swarna S⋅Ramaswamy, Swarna S⋅Johnson, Derrick E⋅Johnson, Derrick E⋅Johnson, Derrick E⋅Vitturi, Dario A⋅Vitturi, Dario A⋅Vitturi, Dario A⋅Schopfer, Franciso J⋅Schopfer, Franciso J⋅Schopfer, Franciso J⋅Freeman, Bruce A⋅Freeman, Bruce A⋅Freeman, Bruce A⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Levitan, Edwin S⋅Levitan, Edwin S and Levitan, Edwin S
Scientific reports, vol. 6, pp. 23416, April 15, 2016. | Journal Article
2015
CaMKII Controls Whether Touch Is Painful.
Yu, Hongwei⋅Yu, Hongwei⋅Yu, Hongwei⋅Yu, Hongwei⋅Pan, Bin⋅Pan, Bin⋅Pan, Bin⋅Pan, Bin⋅Weyer, Andy⋅Weyer, Andy⋅Weyer, Andy⋅Weyer, Andy⋅Wu, Hsiang-En⋅Wu, Hsiang-En⋅Wu, Hsiang-En⋅Wu, Hsiang-En⋅Meng, Jingwei⋅Meng, Jingwei⋅Meng, Jingwei⋅Meng, Jingwei⋅Fischer, Gregory⋅Fischer, Gregory⋅Fischer, Gregory⋅Fischer, Gregory⋅Vilceanu, Daniel⋅Vilceanu, Daniel⋅Vilceanu, Daniel⋅Vilceanu, Daniel⋅Light, Alan R⋅Light, Alan R⋅Light, Alan R⋅Light, Alan R⋅Stucky, Cheryl⋅Stucky, Cheryl⋅Stucky, Cheryl⋅Stucky, Cheryl⋅Rice, Frank L⋅Rice, Frank L⋅Rice, Frank L⋅Rice, Frank L⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Hogan, Quinn⋅Hogan, Quinn⋅Hogan, Quinn and Hogan, Quinn
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 35, (no. 42), pp. 14086-14102, October 21, 2015. | Journal Article
 
Differential expression of CaMKII isoforms and overall kinase activity in rat dorsal root ganglia after injury.
Bangaru, M L Y⋅Meng, J⋅Kaiser, D J⋅Yu, H⋅Fischer, G⋅Hogan, Q H and Hudmon, A
Neuroscience, vol. 300, pp. 116-127, August 6, 2015. | Journal Article
 
Excitotoxic insult results in a long-lasting activation of CaMKIIα and mitochondrial damage in living hippocampal neurons.
Otmakhov, Nikolai⋅Otmakhov, Nikolai⋅Gorbacheva, Elena V⋅Gorbacheva, Elena V⋅Regmi, Shaurav⋅Regmi, Shaurav⋅Yasuda, Ryohei⋅Yasuda, Ryohei⋅Hudmon, Andy⋅Hudmon, Andy⋅Lisman, John and Lisman, John
PloS one, vol. 10, (no. 3), pp. e0120881, 2015. | Journal Article
 
Phosphoregulation of Cardiac Inotropy via Myosin Binding Protein-C During Increased Pacing Frequency or β1-Adrenergic Stimulation.
Tong, Carl W⋅Tong, Carl W⋅Tong, Carl W⋅Wu, Xin⋅Wu, Xin⋅Wu, Xin⋅Liu, Yang⋅Liu, Yang⋅Liu, Yang⋅Rosas, Paola C⋅Rosas, Paola C⋅Rosas, Paola C⋅Sadayappan, Sakthivel⋅Sadayappan, Sakthivel⋅Sadayappan, Sakthivel⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Muthuchamy, Mariappan⋅Muthuchamy, Mariappan⋅Muthuchamy, Mariappan⋅Powers, Patricia A⋅Powers, Patricia A⋅Powers, Patricia A⋅Valdivia, Héctor H⋅Valdivia, Héctor H⋅Valdivia, Héctor H⋅Moss, Richard L⋅Moss, Richard L and Moss, Richard L
Circulation. Heart failure, vol. 8, (no. 3), pp. 595-604, May 2015. | Journal Article
 
Phosphorylation of a Myosin Motor by TgCDPK3 Facilitates Rapid Initiation of Motility during Toxoplasma gondii egress.
Gaji, Rajshekhar Y⋅Gaji, Rajshekhar Y⋅Johnson, Derrick E⋅Johnson, Derrick E⋅Treeck, Moritz⋅Treeck, Moritz⋅Wang, Mu⋅Wang, Mu⋅Hudmon, Andy⋅Hudmon, Andy⋅Arrizabalaga, Gustavo and Arrizabalaga, Gustavo
PLoS pathogens, vol. 11, (no. 11), pp. e1005268, 2015. | Journal Article