18 Publications
2018
A dynamic map for learning, communicating, navigating and improving therapeutic development
Wagner, John⋅Wagner, John⋅Dahlem, Andrew M⋅Dahlem, Andrew M⋅Hudson, Lynn D⋅Hudson, Lynn D⋅Terry, Sharon F⋅Terry, Sharon F⋅Altman, Russ B⋅Altman, Russ B⋅Gilliland, C Taylor⋅Gilliland, C Taylor⋅DeFeo, Christopher⋅DeFeo, Christopher⋅Austin, Christopher P and Austin, Christopher P
Nature reviews. Drug discovery, vol. 17, (no. 2), pp. 150, 2018-02-00. | Journal Article
 
Application of a Dynamic Map for Learning, Communicating, Navigating, and Improving Therapeutic Development
Wagner, John A⋅Wagner, John A⋅Dahlem, Andrew M⋅Dahlem, Andrew M⋅Hudson, Lynn D⋅Hudson, Lynn D⋅Terry, Sharon F⋅Terry, Sharon F⋅Altman, Russ B⋅Altman, Russ B⋅Gilliland, C Taylor⋅Gilliland, C. Taylor⋅DeFeo, Christopher⋅DeFeo, Christopher⋅Austin, Christopher P and Austin, Christopher P
Clinical and Translational Science, vol. 11, (no. 2), pp. 174, March 2018. | Journal Article
2012
Transforming Drug Development: A Case Study
Torrey, Kathryn⋅Grace, James and Dahlem, Andrew
Pharmaceutical Executive, vol. 32, (no. 12), pp. 24, 20121201. | Journal Article
 
Transforming drug development: a case study: Eli Lilly's pioneering pact with leading CRO Covance made big news when it happened. Four years later, both parties can point to metrics that suggest the benefit is mutual
Torrey, Kathryn⋅Grace, James and Dahlem, Andrew
Pharmaceutical Executive, vol. 32, (no. 12), pp. 24, 20121201. | Journal Article
1995
Concomitant Toxicokinetics: Techniques for and Interpretation of Exposure Data Obtained During the Conduct of Toxicology Studies
Dahlem, Andrew M⋅Allerheiligen, Sandra R and Vodicnik, Mary Jo
Toxicologic Pathology, vol. 23, (no. 2), pp. 178, 19950300. | Journal Article
1993
Structural modifications imparting reduced toxicity in microcystins from Microcystis spp
Stotts, RR⋅Stotts, Richard R⋅Namikoshi, M.⋅Namikoshi, Michio⋅Haschek, WM⋅Haschek, Wanda M⋅Rinehart, KL⋅Rinehart, Kenneth L⋅Carmichael, Wayne W⋅Carmichael, Wayne W⋅Dahlem, AM⋅Dahlem, Andrew M⋅Beasley, VR and Beasley, Val R
Toxicon, vol. 31, (no. 6), pp. 789, 1993. | Journal Article
1992
Identification of 12 hepatotoxins from a Homer Lake bloom of the cyanobacteria Microcystis aeruginosa, Microcystis viridis, and Microcystis wesenbergii: nine new microcystins
Namikoshi, Michio⋅Rinehart, Kenneth L⋅Sakai, Ryuichi⋅Stotts, Richard R⋅Dahlem, Andrew M⋅Beasley, Val R⋅Carmichael, Wayne W and Evans, William R
The Journal of Organic Chemistry, vol. 57, (no. 3), pp. 872, 19920101. | Journal Article
1991
Uptake and subcellular localization of tritiated dihydro-microcystin-LR in rat liver
Hooser, S B⋅Hooser, Stephen B⋅Hooser, Stephen B.⋅Kuhlenschmidt, Mark S.⋅Kuhlenschmidt, M S⋅Kuhlenschmidt, Mark S⋅Dahlem, Andrew M.⋅Dahlem, Andrew M⋅Dahlem, A M⋅Beasley, V R⋅Beasley, Val R⋅Beasley, Val R.⋅Carmichael, Wayne W⋅Carmichael, Wayne W⋅Carmichael, Wayne W.⋅Haschek, Wanda M.⋅Haschek, W M and Haschek, Wanda M
Toxicon, vol. 29, (no. 6), pp. 601, 1991. | Journal Article
1990
Internal surface reversed-phase high-performance liquid chromatographic separation of the cyanobacterial peptide toxins microcystin-LA, -LR, -YR, -RR and nodularin
Meriluoto, J.A.O.⋅Meriluoto, J A⋅Meriluoto, Jussi A.O⋅Eriksson, J.E.⋅Eriksson, John⋅Eriksson, John E⋅Harada, K.-I.⋅Harada, Ken-Ichi⋅Harada, K⋅Dahlem, Andrew M⋅Dahlem, A M⋅Dahlem, A.M.⋅Sivonen, Kaarina⋅Sivonen, K⋅Sivonen, K.⋅Carmichael, W.W.⋅Carmichael, Wayne W and Carmichael, Wayne W
Journal of Chromatography A, vol. 509, (no. 2), pp. 395, 1990. | Journal Article
 
Isolation and characterization of the minor components associated with microcystins LR and RR in the cyanobacterium (blue-green algae)
Harada, K-I⋅Harada, Ken-ichi⋅Matsuura, K.⋅Matsuura, Kenji⋅Suzuki, M.⋅Suzuki, Makoto⋅Watanabe, MF⋅Watanabe, Mariyo F⋅Oishi, Shinshi⋅Oishi, S.⋅Dahlem, Andrew M⋅Dahlem, AM⋅Beasley, VR⋅Beasley, Val R⋅Carmichael, Wayne W and Carmichael, Wayne W
Toxicon, vol. 28, (no. 1), pp. 64, 1990. | Journal Article
 
Synthesis, organotropism and hepatocellular uptake of two tritium-labeled epimers of dihydromicrocystin-LR, a cyanobacterial peptide toxin analog
Meriluoto, J.A.O.⋅Meriluoto, JAO⋅Meriluoto, Jussi A.O⋅Nyg?rd, S.E.⋅Nygaard, SE⋅Nygård, Siv E⋅Dahlem, Andrew M⋅Dahlem, AM⋅Dahlem, A.M.⋅Eriksson, John⋅Eriksson, J.E. and Eriksson, John E
Toxicon, vol. 28, (no. 12), pp. 1446, 1990. | Journal Article
1989
Algae Intoxication in Livestock and Waterfowl
Beasley, Val Richard⋅Beasley, Val Richard⋅Cook, William O.⋅Cook, William O⋅Dahlem, Andrew M⋅Dahlem, Andrew M.⋅Hooser, Stephen B.⋅Hooser, Stephen B⋅Lovell, Randall A.⋅Lovell, Randall A⋅Valentine, William M. and Valentine, William M
Veterinary Clinics of North America: Food Animal Practice, vol. 5, (no. 2), pp. 361, July 1989. | Journal Article
 
A Model System for Studying the Bioavailability of Intestinally Administered Microcystin-LR, A Hepatotoxic Peptide from the CyanobacteriumMicrocystis aeruginosa
Dahlem, Andrew M⋅Hassan, Aslam S⋅Swanson, Steven P⋅Carmichael, Wayne W and Beasley, Val R
Pharmacology & Toxicology, vol. 64, (no. 2), pp. 181, 1989-02-00. | Journal Article
 
A new procedure for the analysis and purification of naturally occurring anatoxin-a from the blue-green alga Anabaena flos-aquae
Harada, K⋅Harada, Ken-Ichi⋅Kimura, Yukio⋅Kimura, Y⋅Ogawa, Kiyoshi⋅Ogawa, K⋅Suzuki, Makoto⋅Suzuki, M⋅Dahlem, Andrew M⋅Dahlem, A M⋅Beasley, Val R⋅Beasley, V R⋅Carmichael, Wayne W and Carmichael, Wayne W
Toxicon, vol. 27, (no. 12), pp. 1296, 1989. | Journal Article
 
Regional brain cholinesterase activity in rats injected intraperitoneally with anatoxin-a(s) or paraoxon
Cook, William O⋅Dellinger, John A⋅Singh, Sherene S⋅Dahlem, Andrew M⋅Carmichael, Wayne W and Beasley, Val R
Toxicology Letters, vol. 49, (no. 1), pp. 34, 1989. | Journal Article
 
Total synthesis of Adda, the unique C20 amino acid of cyanobacterial hepatotoxins
Namikoshi, Michio⋅Rinehart, Kenneth L⋅Dahlem, Andrew M⋅Beasley, Val R and Carmichael, Wayne W
Tetrahedron Letters, vol. 30, (no. 33), pp. 4352, 1989-01-00. | Journal Article
1988
Analysis and purification of toxic peptides from cyanobacteria by reversed-phase high-performance liquid chromatography
Harada, Ken-Ichi⋅Matsuura, Kenji⋅Suzuki, Makoto⋅Oka, Hisao⋅Watanabe, Mariyo F⋅Oishi, Shinshi⋅Dahlem, Andrew M⋅Beasley, Val R and Carmichael, Wayne W
Journal of Chromatography A, vol. 448, pp. 283, 1988. | Journal Article
 
Improved method for purification of toxic peptides produced by cyanobacteria
Harada, Ken-ichi⋅Suzuki, Makoto⋅Dahlem, Andrew M⋅Beasley, Val R⋅Carmichael, Wayne W and Rinehart, Kenneth L
Toxicon, vol. 26, (no. 5), pp. 439, 1988. | Journal Article