55 Publications (Page 2 of 3)
2013
A GPR18‐based signalling system regulates IOP in murine eye
Caldwell, Meggie D⋅Caldwell, Meggie D⋅Hu, Sherry Shu‐Jung⋅Hu, Sherry Shu-Jung⋅Viswanathan, Suresh⋅Viswanathan, Suresh⋅Bradshaw, Heather⋅Bradshaw, Heather⋅Kelly, Melanie E M⋅Kelly, Melanie EM⋅Straiker, Alex and Straiker, Alex
British Journal of Pharmacology, vol. 169, (no. 4), pp. 843, June 2013. | Journal Article
 
Diacylglycerol lipaseα (DAGLα) and DAGLβ cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons
Jain, Tarun⋅Jain, Tarun⋅Wager-Miller, Jim⋅Wager Miller, Jim⋅Mackie, Ken⋅Mackie, Ken⋅Straiker, Alex and Straiker, Alex
Molecular pharmacology, vol. 84, (no. 2), pp. 302, 2013-Aug. | Journal Article
 
Fmr1 deletion enhances and ultimately desensitizes CB(1) signaling in autaptic hippocampal neurons.
Straiker, Alex⋅Min, Kyung-Tai and Mackie, Kenneth P
Neurobiology of disease, vol. 56, pp. 1-5, 2013/Aug. | Journal Article
 
GPR55, a G-Protein Coupled Receptor for Lysophosphatidylinositol, Plays a Role in Motor Coordination
Wu, Chia-Shan⋅Wu, Chia-Shan⋅Chen, Hongmei⋅Chen, Hongmei⋅Sun, Hao⋅Sun, Hao⋅Zhu, Jie⋅Zhu, Jie⋅Jew, Chris P⋅Jew, Chris P⋅Wager-Miller, James⋅Wager-Miller, James⋅Straiker, Alex⋅Straiker, Alex⋅Spencer, Corinne⋅Spencer, Corinne⋅Bradshaw, Heather B⋅Bradshaw, Heather⋅Mackie, Ken⋅Mackie, Ken⋅Lu, Hui-Chen and Lu, Hui Chen
PloS one, vol. 8, (no. 4), pp. e60314, 2013-00-00. | Journal Article
2012
CB₂ cannabinoid receptors inhibit synaptic transmission when expressed in cultured autaptic neurons.
Atwood, Brady K⋅Straiker, Alex and Mackie, Kenneth P
Neuropharmacology, vol. 63, (no. 4), pp. 514-23, 2012/Sep. | Journal Article
 
Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones.
Straiker, Alex⋅Straiker, Alex⋅Wager-Miller, Jim⋅Wager Miller, Jim⋅Hutchens, Jacqueline⋅Hutchens, Jacqueline⋅Mackie, Ken and Mackie, Kenneth P
British journal of pharmacology, vol. 165, (no. 8), pp. 2660-71, 2012/Apr. | Journal Article
 
Functional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands.
Atwood, Brady K⋅Wager-Miller, James⋅Haskins, Christopher⋅Straiker, Alex and Mackie, Kenneth P
Molecular pharmacology, vol. 81, (no. 2), pp. 250-63, 2012/Feb. | Journal Article
 
The CB1 cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones.
Straiker, Alex⋅Straiker, Alex⋅Wager Miller, Jim⋅Wager-Miller, Jim⋅Mackie, Ken and Mackie, Kenneth P
British journal of pharmacology, vol. 165, (no. 8), pp. 2652-9, 2012/Apr. | Journal Article
 
The endocannabinoid N-arachidonoyldopamine (NADA) exerts neuroprotective effects after excitotoxic neuronal damage via cannabinoid receptor 1 (CB1)
Grabiec, Urszula⋅Koch, Marco⋅Kallendrusch, Sonja⋅Kraft, Robert⋅Hill, Kerstin⋅Merkwitz, Claudia⋅Ghadban, Chalid⋅Lutz, Beat⋅Straiker, Alex and Dehghani, Faramarz
Neuropharmacology, vol. 62, (no. 4), pp. 1807, March 2012. | Journal Article
2011
COX-2 and fatty acid amide hydrolase can regulate the time course of depolarization-induced suppression of excitation.
Straiker, Alex⋅Wager-Miller, J⋅Hu, S S⋅Blankman, J L⋅Cravatt, B F and Mackie, Kenneth P
British journal of pharmacology, vol. 164, (no. 6), pp. 1672-83, 2011/Nov. | Journal Article
 
CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists.
Atwood, Brady K⋅Lee, Donghoon⋅Straiker, Alex⋅Widlanski, Theodore S and Mackie, Kenneth P
European journal of pharmacology, vol. 659, (no. 2-3), pp. 139-45, 2011/Jun/1. | Journal Article
 
Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis.
Atwood, Brady K⋅Lopez, Jacqueline⋅Wager-Miller, James⋅Mackie, Kenneth P and Straiker, Alex
BMC genomics, vol. 12, pp. 14, 2011. | Journal Article
 
Indirect sympatholytic actions at β-adrenoceptors account for the ocular hypotensive actions of cannabinoid receptor agonists
Hudson, Brian D⋅Hudson, Brian D⋅Beazley, Meggie⋅Beazley, Meggie⋅Szczesniak, Anna-Maria⋅Szczesniak, Anna-Maria⋅Straiker, Alex⋅Straiker, Alex⋅Kelly, Melanie E M and Kelly, Melanie E
The Journal of pharmacology and experimental therapeutics, vol. 339, (no. 3), pp. 767, 2011-Dec. | Journal Article
2010
Architecture of cannabinoid signaling in mouse retina.
Hu, Sherry S⋅Arnold, Andy⋅Hutchens, Jacqueline M⋅Radicke, Josh⋅Cravatt, Benjamin F⋅Wager-Miller, Jim⋅Mackie, Kenneth P and Straiker, Alex
The Journal of comparative neurology, vol. 518, (no. 18), pp. 3848-66, 2010/Sep/15. | Journal Article
 
JWH018, a common constituent of Spice herbal blends, is a potent and efficacious cannabinoid CB1 receptor agonist
Atwood, Brady K⋅Atwood, Brady⋅Huffman, John⋅Huffman, John W⋅Straiker, Alex⋅Straiker, Alex⋅Mackie, Kenneth and Mackie, Ken
British Journal of Pharmacology, vol. 160, (no. 3), pp. 593, June 2010. | Journal Article
 
JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist
Atwood, Brady K⋅Atwood, Brady K⋅Huffman, John W⋅Huffman, John⋅Straiker, Alex⋅Straiker, Alex⋅Mackie, Ken and Mackie, Kenneth P
British journal of pharmacology, vol. 160, (no. 3), pp. 585, 2010-Jun. | Journal Article
2009
Cannabinoid CB1 receptor-dependent long-term depression in autaptic excitatory neurons.
Kellogg, Ryan⋅Mackie, Kenneth P and Straiker, Alex
Journal of neurophysiology, vol. 102, (no. 2), pp. 1160-71, 2009/Aug. | Journal Article
 
Cannabinoid signaling in inhibitory autaptic hippocampal neurons.
Straiker, Alex and Mackie, Kenneth P
Neuroscience, vol. 163, (no. 1), pp. 190-201, 2009/Sep/29. | Journal Article
 
Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons.
Straiker, Alex⋅Straiker, Alex⋅Straiker, Alex⋅Hu, Sherry S⋅Hu, Sherry⋅Hu, Sherry Shu-Jung⋅Long, Jonathan Z.⋅Long, Jonathan⋅Long, Jonathan Z⋅Arnold, Andy⋅Arnold, Andy⋅Arnold, Andy⋅Wager-Miller, Jim⋅Wager Miller, Jim⋅Wager-Miller, Jim⋅Cravatt, Benjamin⋅Cravatt, Benjamin F.⋅Cravatt, Benjamin F⋅Mackie, Ken⋅Mackie, Kenneth P and Mackie, Ken
Molecular pharmacology, vol. 76, (no. 6), pp. 1220-7, 2009/Dec. | Journal Article
2008
Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain.
Moussaieff, Arieh⋅Rimmerman, Neta⋅Bregman, Tatiana⋅Straiker, Alex⋅Felder, Christian C⋅Shoham, Shai⋅Kashman, Yoel⋅Huang, Susan M⋅Lee, Hyosang⋅Shohami, Esther⋅Mackie, Kenneth⋅Caterina, Michael J⋅Walker, J. M⋅Fride, Ester and Mechoulam, Raphael
FASEB journal., vol. 22, (no. 8), pp. 3024-3034, 2008. | Journal Article
2007
Metabotropic suppression of excitation in murine autaptic hippocampal neurons.
Straiker, Alex and Mackie, Ken
The Journal of physiology, vol. 578, pp. 773-785, February 1, 2007. | Journal Article
2006
Cannabinoids, electrophysiology, and retrograde messengers: challenges for the next 5 years.
Straiker, Alex and Mackie, Ken
The AAPS journal, vol. 8, (no. 2), pp. E272-6, 2006. | Journal Article
 
Experimental autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection
Witting, Anke⋅Chen, Lanfen⋅Cudaback, Eiron⋅Straiker, Alex⋅Walter, Lisa⋅Rickman, Barry⋅Moeller, Thomas⋅Brosnan, Celia and Stella, Nephi
Proceedings of the National Academy of Sciences, USA, vol. 103, (no. 16), pp. 6362-6367, 2006. | Journal Article
2005
Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones.
Straiker, Alex and Mackie, Ken
The Journal of physiology, vol. 569, pp. 501-517, December 1, 2005. | Journal Article
2003
Cannabinoid Receptor Activation Differentially Modulates Ion Channels in Photoreceptors of the Tiger Salamander
Straiker, Alex and Sullivan, JM
Journal of Neurophysiology, vol. 89, (no. 5), pp. 2647-2654, 2003. | Journal Article