23 Publications
2016
CD40 promotes MHC class II expression on adipose tissue macrophages and regulates adipose tissue CD4+ T cells with obesity.
Morris, David L⋅Oatmen, Kelsie E⋅Mergian, Taleen A⋅Cho, Kae Won⋅DelProposto, Jennifer L⋅Singer, Kanakadurga⋅Evans-Molina, Carmella⋅O'Rourke, Robert W and Lumeng, Carey N
Journal of leukocyte biology, vol. 99, (no. 6), pp. 1107-1119, June 2016. | Journal Article
 
Metabolic dysfunction and adipose tissue macrophages: is there more to glean from studying the lean?: Comment on "Adipose tissue infiltration in normal-weight subjects and its impact on metabolic function" by Moreno-Indias et al
Morris, David⋅Morris, D. L.⋅Evans-Molina, C. and Evans Molina, Carmella
Transl Res, vol. 172, pp. 1-5. | Journal Article
2015
Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes.
Filgueiras, Luciano Ribeiro⋅Filgueiras, Luciano Ribeiro⋅Brandt, Stephanie L⋅Brandt, Stephanie L⋅Wang, Soujuan⋅Wang, Soujuan⋅Wang, Zhuo⋅Wang, Zhuo⋅Morris, David L⋅Morris, David L⋅Evans Molina, Carmella⋅Evans-Molina, Carmella⋅Mirmira, Raghavendra G⋅Mirmira, Raghavendra G⋅Jancar, Sonia⋅Jancar, Sonia⋅Serezani, C Henrique and Serezani, C Henrique
Science signaling, vol. 8, (no. 361), pp. ra10, January 27, 2015. | Journal Article
 
Minireview: Emerging Concepts in Islet Macrophage Biology in Type 2 Diabetes.
Morris, David L
Molecular endocrinology (Baltimore, Md.), vol. 29, (no. 7), pp. 946-962, July 2015. | Journal Article
 
SET7/9 Enzyme Regulates Cytokine-induced Expression of Inducible Nitric-oxide Synthase through Methylation of Lysine 4 at Histone 3 in the Islet β Cell.
Fujimaki, Kyoko⋅Fujimaki, Kyoko⋅Ogihara, Takeshi⋅Ogihara, Takeshi⋅Morris, David L⋅Morris, David L⋅Oda, Hisanobu⋅Oda, Hisanobu⋅Iida, Hitoshi⋅Iida, Hitoshi⋅Fujitani, Yoshio⋅Fujitani, Yoshio⋅Mirmira, Raghavendra G⋅Mirmira, Raghavendra G⋅Evans-Molina, Carmella⋅Evans Molina, Carmella⋅Watada, Hirotaka and Watada, Hirotaka
The Journal of biological chemistry, vol. 290, (no. 27), pp. 16607-16618, July 3, 2015. | Journal Article
2014
An MHC II-dependent activation loop between adipose tissue macrophages and CD4+ T cells controls obesity-induced inflammation.
Cho, Kae Won⋅Morris, David L⋅DelProposto, Jennifer L⋅Geletka, Lynn⋅Zamarron, Brian⋅Martinez-Santibanez, Gabriel⋅Meyer, Kevin A⋅Singer, Kanakadurga⋅O’Rourke, R. W.⋅O'Rourke, Robert W and Lumeng, Carey N
Cell reports, vol. 9, (no. 2), pp. 605-617, October 23, 2014. | Journal Article
 
Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells.
Singer, Kanakadurga⋅DelProposto, Jennifer⋅Morris, David L⋅Zamarron, Brian F⋅Mergian, Taleen⋅Maley, Nidhi⋅Cho, Kae W⋅Geletka, Lynn⋅Subbaiah, Perla⋅Muir, Lindsey⋅Martinez-Santibanez, Gabriel⋅Nien-Kai Lumeng, Carey and Lumeng, Carey Nien Kai
Molecular metabolism, vol. 3, (no. 6), pp. 664-75, 2014/Sep. | Journal Article
 
Flow cytometry analyses of adipose tissue macrophages.
Cho, Kae W⋅Morris, David L and Lumeng, Carey N
Methods in enzymology, vol. 537, pp. 297-314, 2014. | Journal Article
 
SH2B1 in β-cells promotes insulin expression and glucose metabolism in mice.
Chen, Zheng⋅Morris, David L⋅Jiang, Lin⋅Liu, Yong and Rui, Liangyou
Molecular endocrinology (Baltimore, Md.), vol. 28, (no. 5), pp. 696-705, May 2014. | Journal Article
 
SH2B1 in β-cells regulates glucose metabolism by promoting β-cell survival and islet expansion.
Chen, Zheng⋅Morris, David L⋅Jiang, Lin⋅Liu, Yong and Rui, Liangyou
Diabetes, vol. 63, (no. 2), pp. 585-95, 2014/Feb. | Journal Article
2013
Adipose tissue macrophages function as antigen-presenting cells and regulate adipose tissue CD4+ T cells in mice.
Morris, David L⋅Cho, Kae W⋅Delproposto, Jennifer L⋅Oatmen, Kelsie E⋅Geletka, Lynn M⋅Martinez-Santibanez, Gabriel⋅Singer, Kanakadurga and Lumeng, Carey N
Diabetes, vol. 62, (no. 8), pp. 2762-72, 2013/Aug. | Journal Article
 
Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetes.
Colvin, Stephanie C⋅Maier, Bernhard⋅Morris, David L⋅Tersey, Sarah A and Mirmira, Raghavendra G
The Journal of biological chemistry, vol. 288, (no. 51), pp. 36226-35, 2013/Dec/20. | Journal Article
 
Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains.
Sims, Emily⋅Sims, Emily K⋅Hatanaka, Masayuki⋅Hatanaka, Masayuki⋅Morris, David⋅Morris, David L⋅Tersey, Sarah⋅Tersey, Sarah A⋅Kono, Tatsuyoshi⋅Kono, Tatsuyoshi⋅Chaudry, Zunaira⋅Chaudry, Zunaira Z⋅Day, Kathleen H⋅Day, Kathleen⋅Moss, Dan R⋅Moss, Dan⋅Stull, Natalie D⋅Stull, Natalie⋅Mirmira, Raghavendra⋅Mirmira, Raghavendra G⋅Evans Molina, Carmella and Evans-Molina, Carmella
American journal of physiology. Endocrinology and metabolism, vol. 305, (no. 12), pp. E1495-511, 2013/Dec. | Journal Article
 
Neuropeptide Y Is Produced by Adipose Tissue Macrophages and Regulates Obesity-Induced Inflammation. e57929
Singer, Kanakadurga⋅Morris, David L⋅Oatmen, Kelsie E⋅Wang, Tianyi⋅DelProposto, Jennifer⋅Mergian, Taleen⋅Cho, Kae W and Lumeng, Carey
PLoS ONE, vol. 8, (no. 3), 2013. | Journal Article
 
Phosphorylation of the adaptor protein SH2B1β regulates its ability to enhance growth hormone-dependent macrophage motility.
Su, Hsiao-Wen⋅Lanning, Nathan J⋅Morris, David L⋅Argetsinger, Larry⋅Lumeng, Carey N and Carter Su, Christin
Journal of cell science, vol. 126, (no. Pt 8), pp. 1733-43, 2013/Apr/15. | Journal Article
 
Streptozotocin is equally diabetogenic whether administered to fed or fasted mice.
Chaudhry, Zunaira Z⋅Chaudhry, Zunaira Z⋅Morris, David L⋅Morris, David L⋅Moss, Dan R⋅Moss, Dan R⋅Sims, Emily K⋅Sims, Emily K⋅Chiong, Yien⋅Chiong, Yien⋅Kono, Tatsuyoshi⋅Kono, Tatsuyoshi⋅Evans Molina, Carmella and Evans-Molina, Carmella
Laboratory animals, vol. 47, (no. 4), pp. 257-65, 2013/Oct. | Journal Article
2012
CX3CR1 deficiency does not influence trafficking of adipose tissue macrophages in mice with diet-induced obesity.
Morris, David L⋅Oatmen, Kelsie E⋅Wang, Tianyi⋅DelProposto, Jennifer L and Lumeng, Carey N
Obesity (Silver Spring, Md.), vol. 20, (no. 6), pp. 1189-99, 2012/Jun. | Journal Article
2011
Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states.
Morris, David L⋅Singer, Kanakadurga and Lumeng, Carey N
Current opinion in clinical nutrition and metabolic care, vol. 14, (no. 4), pp. 341-6, 2011/Jul. | Journal Article
2010
Critical role of the Src homology 2 (SH2) domain of neuronal SH2B1 in the regulation of body weight and glucose homeostasis in mice.
Morris, David L⋅Cho, Kae W and Rui, Liangyou
Endocrinology, vol. 151, (no. 8), pp. 3643-51, 2010/Aug. | Journal Article
2009
Recent advances in understanding leptin signaling and leptin resistance.
Morris, David L and Rui, Liangyou
American journal of physiology. Endocrinology and metabolism, vol. 297, (no. 6), pp. E1247-59, 2009/Dec. | Journal Article
 
SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins.
Morris, David L⋅Cho, Kae W⋅Zhou, Yingjiang and Rui, Liangyou
Diabetes, vol. 58, (no. 9), pp. 2039-47, 2009/Sep. | Journal Article
2007
Identification of SH2B2beta as an inhibitor for SH2B1- and SH2B2alpha-promoted Janus kinase-2 activation and insulin signaling.
Li, Minghua⋅Li, Zhiqin⋅Morris, David L and Rui, Liangyou
Endocrinology, vol. 148, (no. 4), pp. 1615-21, 2007/Apr. | Journal Article
 
Neuronal SH2B1 is essential for controlling energy and glucose homeostasis
Ren, Decheng⋅Zhou, Yingjiang⋅Morris, David⋅Li, Minghua⋅Li, Zhiqin and Rui, Liangyou
Journal of Clinical Investigation, vol. 117, (no. 2), pp. 397-406, 2007. | Journal Article