20 Publications
2017
Phosphatase PRL2 promotes AML1-ETO-induced acute myeloid leukemia
Kobayashi, M⋅Chen, S⋅Bai, Y⋅Yao, C⋅Gao, R⋅Sun, X-j⋅Mu, C⋅Twiggs, T⋅Yu, Z-h⋅Boswell, H⋅Yoder, M⋅Kapur, R⋅Mulloy, J⋅Zhang, Z-y and Liu, Y
Leukemia, vol. 31, (no. 6), pp. 1453-1457, Jun 2017. | Journal Article
2016
Death-associated Protein Kinase-1 Expression and Autophagy in Chronic Lymphocytic Leukemia Are Dependent on Activating Transcription Factor-6 and CCAAT/Enhancer-binding Protein-β.
Gade, Padmaja⋅Kimball, Amy S⋅DiNardo, Angela C⋅Gangwal, Priyamvada⋅Ross, Douglas D⋅Boswell, H Scott⋅Keay, Susan K and Kalvakolanu, Dhananjaya V
The Journal of biological chemistry, vol. 291, (no. 42), pp. 22030-22042, October 14, 2016. | Journal Article
 
Syk kinase and Shp2 phosphatase inhibition cooperate to reduce FLT3-ITD-induced STAT5 activation and proliferation of acute myeloid leukemia.
Richine, B M⋅Virts, E L⋅Bowling, J D⋅Ramdas, B⋅Mali, R⋅Naoye, R⋅Liu, Z⋅Zhang, Z-Y⋅Boswell, H S⋅Kapur, R and Chan, R J
Leukemia, June 3, 2016. | Journal Article
2014
Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner.
Wang, Lin⋅Wang, Lin⋅Wang, Lin⋅Wang, Lin⋅Zhang, Huajia⋅Zhang, Huajia⋅Zhang, Huajia⋅Zhang, Huajia⋅Rodriguez, Sonia⋅Rodriguez, Sonia⋅Rodriguez, Sonia⋅Rodriguez, Sonia⋅Cao, Liyun⋅Cao, Liyun⋅Cao, Liyun⋅Cao, Liyun⋅Parish, Jonathan⋅Parish, Jonathan⋅Parish, Jonathan⋅Parish, Jonathan⋅Mumaw, Christen⋅Mumaw, Christen⋅Mumaw, Christen⋅Mumaw, Christen⋅Zollman, Amy⋅Zollman, Amy⋅Zollman, Amy⋅Zollman, Amy⋅Kamoka, Malgorzata M.⋅Kamoka, Malgorzata M⋅Kamoka, Malgorzata M⋅Kamoka, Malgorzata M⋅Mu, Jian⋅Mu, Jian⋅Mu, Jian⋅Mu, Jian⋅Chen, Danny Z⋅Chen, Danny Z.⋅Chen, Danny Z⋅Chen, Danny Z⋅Srour, Edward F⋅Srour, Edward F.⋅Srour, Edward F⋅Srour, Edward F⋅Chitteti, Brahmananda R⋅Chitteti, Brahmananda R⋅Chitteti, Brahmananda R.⋅Chitteti, Brahmananda R⋅HogenEsch, Harm⋅HogenEsch, Harm⋅HogenEsch, Harm⋅HogenEsch, Harm⋅Tu, Xiaolin⋅Tu, Xiaolin⋅Tu, Xiaolin⋅Tu, Xiaolin⋅Bellido, Teresita M⋅Bellido, Teresita M.⋅Bellido, Teresita M⋅Bellido, Teresita M⋅Boswell, H. Scott⋅Boswell, H Scott⋅Boswell, H. Scott⋅Boswell, H. Scott⋅Manshouri, Taghi⋅Manshouri, Taghi⋅Manshouri, Taghi⋅Manshouri, Taghi⋅Verstovsek, Srdan⋅Verstovsek, Srdan⋅Verstovsek, Srdan⋅Verstovsek, Srdan⋅Yoder, Mervin C⋅Yoder, Mervin C.⋅Yoder, Mervin C⋅Yoder, Mervin C⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Cardoso, Angelo A.⋅Cardoso, Angelo A⋅Cardoso, Angelo A⋅Cardoso, Angelo A⋅Carlesso, Nadia⋅Carlesso, Nadia⋅Carlesso, Nadia and Carlesso, Nadia
Cell stem cell, vol. 15, (no. 1), pp. 51-65, July 3, 2014. | Journal Article
 
Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis.
Chatterjee, Anindya⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Martin, Holly⋅Martin, Holly⋅Martin, Holly⋅Kobayashi, Michihiro⋅Kobayashi, Michihiro⋅Kobayashi, Michihiro⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Canela, Victor H⋅Canela, Victor H⋅Canela, Victor H⋅Waskow, Emily R⋅Waskow, Emily R⋅Waskow, Emily R⋅Visconte, Valeria⋅Visconte, Valeria⋅Visconte, Valeria⋅Tiu, Ramon V⋅Tiu, Ramon V⋅Tiu, Ramon V⋅Smith, Catherine C⋅Smith, Catherine C⋅Smith, Catherine C⋅Shah, Neil⋅Shah, Neil⋅Shah, Neil⋅Bunting, Kevin D⋅Bunting, Kevin D⋅Bunting, Kevin D⋅Boswell, H Scott⋅Boswell, H. Scott⋅Boswell, H. Scott⋅Liu, Yan⋅Liu, Yan⋅Liu, Yan⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Kapur, Reuben⋅Kapur, Reuben and Kapur, Reuben
Cell reports, vol. 9, (no. 4), pp. 1333-1348, November 20, 2014. | Journal Article
2013
The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo.
Nabinger, S C⋅Li, X J⋅Ramdas, B⋅He, Y⋅Zhang, X⋅Zeng, L⋅Richine, B⋅Bowling, J D⋅Fukuda, S⋅Goenka, S⋅Liu, Z⋅Feng, G-S⋅Yu, Menggang⋅Sandusky, G E⋅Boswell, H. S⋅Zhang, Z-Y⋅Kapur, Reuben and Chan, R J
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, vol. 27, (no. 2), pp. 398-408, 2013/Feb. | Journal Article
2012
A noncanonical Flt3ITD/NF-κB signaling pathway represses DAPK1 in acute myeloid leukemia.
Shanmugam, Rajasubramaniam⋅Gade, Padmaja⋅Wilson-Weekes, Annique⋅Sayar, Hamid⋅Suvannasankha, Attaya⋅Goswami, Chirayu⋅Li, Lang⋅Gupta, Sushil⋅Cardoso, Angelo A⋅Al Baghdadi, Tareq⋅Sargent, Katie J⋅Cripe, Larry D⋅Kalvakolanu, Dhananjaya V and Boswell, H S
Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 18, (no. 2), pp. 360-9, 2012/Jan/15. | Journal Article
 
Novel combination treatments targeting chronic myeloid leukemia stem cells.
Al Baghdadi, Tareq⋅Abonour, Rafat and Boswell, H. S
Clinical lymphoma, myeloma & leukemia, vol. 12, (no. 2), pp. 94-105, 2012/Apr. | Journal Article
2011
Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL.
Mali, Raghuveer S⋅Mali, Raghuveer Singh⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ma, Peilin⋅Ma, Peilin⋅Shi, Jianjian⋅Shi, Jianjian⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Sims, Emily⋅Sims, Emily⋅Wei, Lei⋅Wei, Lei⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Nabinger, Sarah C⋅Nabinger, Sarah C⋅Goodwin, Charles B⋅Goodwin, Charles B⋅Chan, Rebecca⋅Chan, Rebecca J⋅Traina, Fabiola⋅Traina, Fabiola⋅Visconte, Valeria⋅Visconte, Valeria⋅Tiu, Ramon V⋅Tiu, Ramon V⋅Lewis, Timothy A⋅Lewis, Timothy A⋅Stern, Andrew M⋅Stern, Andrew M⋅Wen, Qiang J⋅Wen, Qiang⋅Crispino, John D⋅Crispino, John⋅Boswell, H. Scott⋅Boswell, H. S⋅Kapur, Reuben and Kapur, Reuben
Cancer cell, vol. 20, (no. 3), pp. 357-69, 2011/Sep/13. | Journal Article
2009
Survivin mediates aberrant hematopoietic progenitor cell proliferation and acute leukemia in mice induced by internal tandem duplication of Flt3.
Fukuda, Seiji⋅Singh, Pratibha⋅Moh, Akira⋅Abe, Mariko⋅Conway, Edward M⋅Boswell, H S⋅Yamaguchi, Seiji⋅Fu, Xin Y and Pelus, Louis M
Blood, vol. 114, (no. 2), pp. 394-403, 2009/Jul/9. | Journal Article
2007
MOZ and MOZ-CBP Cooperate with NFκB To Induce Expression of NFκB-Dependent Genes
Chan, Edward M⋅Chan, Edward M⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Comer, Elisha M⋅Comer, Elisha M⋅Goulet, Robert J⋅Goulet, Robert J⋅Crean, Colin D⋅Crean, Colin D⋅Brown, Zachary D⋅Brown, Zachary D⋅Fruehwald, Amy M⋅Fruehwald, Amy M⋅Yang, Zhenyun⋅Yang, Zhenyun⋅Boswell, Howard S⋅Boswell, Howard S⋅Nakshatri, Harikrishna⋅Nakshatri, Harikrishna⋅Gabig, Theodore G and Gabig, Theodore G
Blood, vol. 110, (no. 11), pp. 887, 2007-11-16. | Journal Article
2006
Constitutive c-jun N-terminal kinase activity in acute myeloid leukemia derives from Flt3 and affects survival and proliferation.
Hartman, Amy D⋅Wilson-Weekes, Annique⋅Suvannasankha, Attaya⋅Burgess, Gem S⋅Phillips, Carissa A⋅Hincher, Katie J⋅Cripe, Larry D and Boswell, H Scott
Experimental hematology, vol. 34, (no. 10), pp. 1360-1376, October 2006. | Journal Article
2002
P21waf-1-Chk1 pathway monitors G1 phase microtubule integrity and is crucial for restriction point transition.
Mantel, Charlie R⋅Gelfano, Vasily M⋅Kim, Young-June⋅McDaniel, Andrew⋅Lee, Younghee⋅Boswell, H S and Broxmeyer, Hal E
Cell cycle (Georgetown, Tex.) , vol. 1, (no. 5), pp. 327-36, 2002 Sep-Oct. | Journal Article
1994
Coupling between p210bcr-abl and Shc and Grb2 adaptor proteins in hematopoietic cells permits growth factor receptor-independent link to ras activation pathway.
Tauchi, T⋅Boswell, H S⋅Leibowitz, D and Broxmeyer, H E
The Journal of experimental medicine, vol. 179, (no. 1), pp. 167-175, January 1, 1994. | Journal Article
1991
Expression of val-12 mutant ras p21 in an IL-3-dependent murine myeloid cell line is associated with loss of serum-dependence and increases in membrane PIP2-specific phospholipase C activity.
Rizzo, M T⋅Boswell, H S⋅English, D and Gabig, T G
Cellular signalling, vol. 3, (no. 4), pp. 311-319, 1991. | Journal Article
1990
A novel mast cell growth factor (MCGF-3) produced by marrow-adherent cells that synergizes with interleukin 3 and interleukin 4.
Boswell, H. S⋅Mochizuki, D Y⋅Burgess, G S⋅Gillis, S⋅Walker, E B⋅Anderson, D and Williams, D E
Experimental Hematology, vol. 18, (no. 7), pp. 794-800, 1990/Aug. | Journal Article
 
A RAS oncogene imparts growth factor independence to myeloid cells that abnormally regulate protein kinase C: a nonautocrine transformation pathway.
Boswell, H. S⋅Nahreini, T S⋅Burgess, G S⋅Srivastava, A⋅Gabig, T G⋅Inhorn, L⋅Srour, E F and Harrington, M A
Experimental Hematology, vol. 18, (no. 5), pp. 452-60, 1990/Jun. | Journal Article
1989
A mutant RAS gene acts through protein kinase C to augment interleukin-3 dependent proliferation in a fastidious immortal myeloid cell line.
Boswell, H. S⋅Harrington, M A⋅Burgess, G S⋅Nahreini, T L⋅Derigs, H G⋅Hodges, T D⋅English, D⋅Crean, C D and Gabig, T G
Leukemia, vol. 3, (no. 9), pp. 662-8, 1989/Sep. | Journal Article
1987
A variant t(X;15)(p11;q22) translocation in acute promyelocytic leukemia.
Srivastava, Arun⋅Heerema, N⋅Lauer, R C⋅Nahreini, P⋅Boswell, H S⋅Hoffman, R and Antony, A C
Cancer Genetics and Cytogenetics, vol. 29, (no. 1), pp. 65-74, 1987/Nov. | Journal Article
 
Cellular control of in vitro progression of murine myeloid leukemia: progression accompanies acquisition of independence from growth factor and stromal cells.
Boswell, H. S⋅Srivastava, A⋅Burgess, J S⋅Nahreini, P⋅Heerema, N⋅Inhorn, L⋅Padgett, F⋅Walker, E B and Geib, R W
Leukemia, vol. 1, (no. 11), pp. 765-71, 1987/Nov. | Journal Article