31 Publications (Page 1 of 2)
2013
Epigenetic targeting therapies to overcome chemotherapy resistance.Balch, Curtis and Nephew, KenAdvances in experimental medicine and biology, vol. 754, pp. 285-311, 2013.
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2012
A unique histone deacetylase inhibitor alters microRNA expression and signal transduction in chemoresistant ovarian cancer cells.Balch, Curtis⋅Naegeli, Kaleb⋅Nam, Seungyoon⋅Ballard, Brett⋅Hyslop, Alan⋅Melki, Christina⋅Reilly, Elizabeth⋅Hur, Man-Wook and Nephew, KenCancer biology & therapy, vol. 13, (no. 8), pp. 681-93, 2012/Jun.
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Growth inhibition of ovarian tumor-initiating cells by niclosamide.Yo, Yi-Te⋅Lin, Ya-Wen⋅Wang, Yu-Chi⋅Balch, Curtis⋅Huang, Rui-Lan⋅Chan, Michael W⋅Sytwu, Huey-Kang⋅Chen, Chi-Kuan⋅Chang, Cheng-Chang⋅Nephew, Ken⋅Huang, Tim⋅Yu, Mu-Hsien and Lai, Hung-ChengMolecular cancer therapeutics, vol. 11, (no. 8), pp. 1703-12, 2012/Aug.
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Subcutaneous 5-Azacitidine Treatment of Naturally Occurring Canine Urothelial Carcinoma: A Novel Epigenetic Approach to Human Urothelial Carcinoma Drug DevelopmentHahn, Noah M⋅Hahn, Noah⋅Bonney, Patty L⋅Bonney, Patty⋅Dhawan, Deepika⋅Dhawan, Deepika⋅Jones, David R⋅Jones, David⋅Balch, Curtis⋅Balch, Curtis⋅Guo, Zhongmin⋅Guo, Zhongmin⋅Hartman-Frey, Corie⋅Hartman-Frey, Corie⋅Fang, Fang⋅Fang, Fang⋅Parker, Heidi G⋅Parker, Heidi⋅Kwon, Erika M⋅Kwon, Erika⋅Ostrander, Elaine A⋅Ostrander, Elaine⋅Nephew, Ken⋅Nephew, Kenneth⋅Knapp, Deborah and Knapp, Deborah WJournal of Urology, vol. 187, (no. 1), pp. 302-309, 2012.
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The influence of cis-regulatory elements on DNA methylation fidelity.Teng, Mingxiang⋅Teng, Mingxiang⋅Balch, Curtis⋅Balch, Curt⋅Liu, Yunlong⋅Liu, Yunlong⋅Li, Meng⋅Li, Meng⋅Huang, Tim H⋅Huang, Tim H M⋅Wang, Yadong⋅Wang, Yadong⋅Nephew, Ken⋅Nephew, Kenneth P⋅Li, Lang and Li, LangPloS one, vol. 7, (no. 3), pp. e32928, 2012.
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2010
A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer.Fang, Fang⋅Fang, Fang⋅Balch, Curtis⋅Balch, Curt⋅Schilder, Jeanne⋅Schilder, Jeanne M⋅Breen, Timothy⋅Breen, Timothy⋅Zhang, Shu⋅Zhang, Shu⋅Shen, Changyu⋅Shen, Changyu⋅Li, Lang⋅Li, Lang⋅Kulesavage, Carol⋅Kulesavage, Carol⋅Snyder, Anthony J⋅Snyder, Anthony J⋅Nephew, Kenneth P⋅Nephew, Ken⋅Matei, Daniela E and Matei, Daniela ECancer, vol. 116, (no. 17), pp. 4043-53, 2010/Sep/1.
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Derepression of CLDN3 and CLDN4 during ovarian tumorigenesis is associated with loss of repressive histone modificationsKwon, Mi J⋅Kim, Sung-Su⋅Choi, Yoon-La⋅Jung, Hun S⋅Balch, Curtis⋅Kim, Su-Hyeong⋅Song, Yong-Sang⋅Marquez, Victor E⋅Nephew, Kenneth P and Shin, Young KCarcinogenesis, vol. 31, (no. 6), pp. 974-983, 2010.
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Epigenetics and Ovarian CancerNephew, Ken⋅Balch, Curtis⋅Zhang, S. and Huang, TH-MCancer Treatment and Research, vol. 149, pp. 131-146, 2010.
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Multivalent epigenetic marks confer microenvironment-responsive epigenetic plasticity to ovarian cancer cells.Bapat, Sharmila A⋅Jin, Victor⋅Berry, Nicholas⋅Balch, Curtis⋅Sharma, Neeti⋅Kurrey, Nawneet⋅Zhang, Shu⋅Fang, Fang⋅Lan, Xun⋅Li, Meng⋅Kennedy, Brian⋅Bigsby, Robert M⋅Huang, Tim H and Nephew, KenEpigenetics : official journal of the DNA Methylation Society, vol. 5, (no. 8), pp. 716-29, 2010 Nov-Dec.
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The role of chromatin, microRNAs, and tumor stem cells in ovarian cancer.Balch, Curtis and Nephew, KenCancer biomarkers : section A of Disease markers, vol. 8, (no. 4-5), pp. 203-21, 2010-2011.
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2009
An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules.Qin, Huaxia⋅Chan, Michael W⋅Liyanarachchi, Sandya⋅Balch, Curtis⋅Potter, Dustin⋅Souriraj, Irene J⋅Cheng, Alfred S⋅Agosto-Perez, Francisco J⋅Nikonova, Elena V⋅Yan, Pearlly S⋅Lin, Huey Jen⋅Nephew, Ken⋅Saltz, Joel H⋅Showe, Louise C⋅Huang, Tim H and Davuluri, Ramana VBMC systems biology, vol. 3, pp. 73, 2009.
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A rationally designed histone deacetylase inhibitor with distinct antitumor activity against ovarian cancer.Yang, Ya-Ting⋅Balch, Curtis⋅Kulp, Samuel K⋅Mand, Michael R⋅Nephew, Ken and Chen, Ching ShihNeoplasia (New York, N.Y.), vol. 11, (no. 6), pp. 552-63, 3 p following 563, 2009/Jun.
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Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistanceXin, Fuxiao⋅Li, Meng⋅Balch, Curtis⋅Thomson, Michael⋅Fan, Meiyun⋅Liu, Yunlong⋅Hammond, Scott M⋅Kim, Sun and Nephew, KenBioinformatics, vol. 25, (no. 4), pp. 430-434, 2009.
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Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer.Li, Meng⋅Balch, Curtis⋅Montgomery, John S⋅Jeong, Mikyoung⋅Chung, Jae H⋅Yan, Pearlly S⋅Huang, Tim H⋅Kim, Sun and Nephew, KenBMC medical genomics, vol. 2, pp. 34, 2009.
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MicroRNA and mRNA integrated analysis (MMIA): a web tool for examining biological functions of microRNA expressionNam, Seungyoon⋅Li, Meng⋅Choi, Kwangmin⋅Balch, Curtis⋅Kim, Sun and Nephew, KenNucleic Acids Research, vol. 37, (no. suppl_2), pp. W356-W362, 2009.
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MicroRNA and mRNA integrated analysis (MMIA): a web tool for examining biological functions of microRNA expression.Nam, Seungyoon⋅Li, Meng⋅Choi, Kwangmin⋅Balch, Curtis⋅Kim, Sun and Nephew, KenNucleic acids research., vol. 37, pp. W356-W362, 2009.
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MicroRNA and mRNA integrated analysis (MMIA): a web tool for examining biological functions of microRNA expression.Nam, Seungyoon⋅Li, Meng⋅Choi, Kwangmin⋅Balch, Curtis⋅Kim, Sun and Nephew, KenNucleic acids research, vol. 37, (no. Web Server issue), pp. W356-62, 2009/Jul.
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Minireview: epigenetic changes in ovarian cancer.Balch, Curtis⋅Balch, Curt⋅Fang, Fang⋅Fang, Fang⋅Matei, Daniela E⋅Matei, Daniela E⋅Huang, Tim H-M⋅Huang, Tim H⋅Nephew, Kenneth P and Nephew, KenEndocrinology, vol. 150, (no. 9), pp. 4003-11, 2009/Sep.
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2008
Enriched transcription factor binding sites in hypermethylated gene promoters in drug resistant cancer cellsLi, Meng⋅Paik, Hyun-il H⋅Balch, Curtis⋅Kim, Yoosung⋅Li, Lang⋅Huang, Tim H⋅Nephew, Ken and Kim, SunBioinformatics, vol. 24, (no. 16), pp. 1745-8, Aug 15, 2008.
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Identification and Characterization of Ovarian Cancer-Initiating Cells from Primary Human TumorsZhang, Shu⋅Zhang, Shu⋅Balch, Curt⋅Balch, Curtis⋅Chan, Michael⋅Chan, Michael W⋅Lai, Hung-Cheng⋅Lai, Hung-Cheng⋅Matei, Daniela E⋅Matei, Daniela⋅Schilder, Jeanne⋅Schilder, Jeanne M⋅Yan, Pearlly⋅Yan, Pearlly S⋅Huang, Tim H⋅Huang, Tim⋅Nephew, Kenneth and Nephew, KenCancer Research, vol. 68, (no. 11), pp. 4311-4320, 2008.
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2007
Epigenetic "bivalently marked" process of cancer stem cell-driven tumorigenesisBalch, Curtis⋅Nephew, Ken⋅Huang, Tim H and Bapat, Sharmila ABioEssays., vol. 29, (no. 9), pp. 842-845, 2007.
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2006
A mixture model-based discriminate analysis for identifying ordered transcription factor binding site pairs in gene promoters directly regulated by estrogen receptor-[alpha]Li, Lang⋅Cheng, Alfred S⋅Jin, Victor⋅Paik, Henry H⋅Fan, Meiyun⋅Li, Xiaoman⋅Zhang, Wei⋅Robarge, Jason⋅Balch, Curtis⋅Davuluri, Ramana V⋅Kim, Sun⋅Huang, Tim H and Nephew, KenBioinformatics, vol. 22, (no. 18), pp. 2210, Sep 15, 2006.
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Dominant-Negative Histone H3 Lysine 27 Mutant Derepresses Silenced Tumor Suppressor Genes and Reverses the Drug-Resistant Phenotype in Cancer CellsAbbosh, Phillip H⋅Montgomery, John S⋅Starkey, Jason A⋅Novotny, Milos⋅Zuhowski, Eleanor G⋅Egorin, Merrill J⋅Moseman, Annie P⋅Golas, Adam⋅Brannon, Kate M⋅Balch, Curtis⋅Huang, Tim H and Nephew, KenCancer Research, vol. 66, (no. 11), pp. 5582-5591, 2006.
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