11 Publications
2021
Randomized, Double-Blind, Controlled Study to Evaluate Safety and Pharmacokinetics of Single Ascending Doses of ASP5354, an Investigational Imaging Product, in Healthy Adult Volunteers.
Murase, ToseiTakizawa, MasaomiGalitz, LawrenceFlach, StephenMurray, ValeneGufford, Brandon and Suwa, Akira
Clinical pharmacology in drug development, August 23, 2021. | Journal Article
2020
Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers
Collins, Kimberly SCollins, Kimberly SCollins, Kimberly SCollins, Kimberly SCollins, Kimberly S.Metzger, Ingrid F.Metzger, Ingrid FMetzger, Ingrid FMetzger, Ingrid FMetzger, Ingrid FGufford, Brandon TGufford, Brandon T.Gufford, Brandon TGufford, Brandon TGufford, Brandon TLu, Jessica BLu, Jessica BLu, Jessica BLu, Jessica BLu, JessicaMedeiros, Elizabeth BMedeiros, Elizabeth BMedeiros, Elizabeth BMedeiros, Elizabeth B.Medeiros, Elizabeth BPratt, Victoria MPratt, Victoria M.Pratt, Victoria MPratt, Victoria MPratt, Victoria MSkaar, Todd CSkaar, Todd CSkaar, Todd CSkaar, Todd CSkaar, Todd C.Desta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, Zeruesenay and Desta, Zeruesenay
Drug metabolism and disposition: the biological fate of chemicals, vol. 48, (no. 3), pp. 175, 2020-Mar. | Journal Article
 
Probenecid‐Boosted Tenofovir: A Physiologically‐Based Pharmacokinetic Model‐Informed Strategy for On‐Demand HIV Preexposure Prophylaxis
Liu, Stephanie NLiu, Stephanie NDesta, ZeruesenayDesta, ZeruesenayGufford, Brandon T and Gufford, Brandon T
CPT: Pharmacometrics & Systems Pharmacology, vol. 9, (no. 1), pp. 47, January 2020. | Journal Article
2019
Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial
Fulton, Cathy RFulton, Cathy RFulton, Cathy RFulton, Cathy RFulton, Cathy RFulton, Cathy RFulton, Cathy RZang, YongZang, YongZang, YongZang, YongZang, YongZang, YongZang, YongDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayRosenman, Marc BRosenman, Marc BRosenman, Marc BRosenman, Marc BRosenman, Marc BRosenman, Marc BRosenman, Marc BHolmes, Ann MHolmes, Ann MHolmes, Ann MHolmes, Ann MHolmes, Ann MHolmes, Ann MHolmes, Ann MDecker, Brian SDecker, Brian SDecker, Brian SDecker, Brian SDecker, Brian SDecker, Brian SDecker, Brian SZhang, YifeiZhang, YifeiZhang, YifeiZhang, YifeiZhang, YifeiZhang, YifeiZhang, YifeiT Callaghan, JohnT Callaghan, JohnT Callaghan, JohnT Callaghan, JohnT Callaghan, JohnT Callaghan, JohnT Callaghan, JohnPratt, Victoria MPratt, Victoria MPratt, Victoria MPratt, Victoria MPratt, Victoria MPratt, Victoria MPratt, Victoria MLevy, Kenneth DLevy, Kenneth DLevy, Kenneth DLevy, Kenneth DLevy, Kenneth DLevy, Kenneth DLevy, Kenneth DGufford, Brandon TGufford, Brandon TGufford, Brandon TGufford, Brandon TGufford, Brandon TGufford, Brandon TGufford, Brandon TDexter, Paul RDexter, Paul RDexter, Paul RDexter, Paul RDexter, Paul RDexter, Paul RDexter, Paul RSkaar, Todd CSkaar, Todd CSkaar, Todd CSkaar, Todd CSkaar, Todd CSkaar, Todd CSkaar, Todd CEadon, Michael TEadon, Michael TEadon, Michael TEadon, Michael TEadon, Michael TEadon, Michael T and Eadon, Michael T
Pharmacogenomics, vol. 20, (no. 6), pp. 408, 20190201. | Journal Article
2018
Developing User Personas to Aid in the Design of a User-Centered Natural Product-Drug Interaction Information Resource for Researchers
Boyce, Richard DRagueneau-Majlessi, IsabelleYu, JingjingTay-Sontheimer, JessicaKinsella, ChrisChou, EricBrochhausen, MathiasJudkins, JohnGufford, Brandon TPinkleton, Bruce ECooney, RebeccaPaine, Mary F and McCune, Jeannine S
AMIA ... Annual Symposium proceedings. AMIA Symposium, vol. 2018, pp. 287, 2018-00-00. | Journal Article
 
Variants in the CYP2B6 3′UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs
Burgess, Kimberly SBurgess, Kimberly SBurgess, Kimberly S.Burgess, Kimberly SBurgess, Kimberly SIpe, JosephIpe, JosephIpe, JosephIpe, JosephIpe, JosephSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeMetzger, Ingrid FMetzger, Ingrid FMetzger, Ingrid FMetzger, Ingrid FMetzger, Ingrid F.Lu, JessicaLu, JessicaLu, JessicaLu, JessicaLu, JessicaGufford, Brandon TGufford, Brandon TGufford, Brandon TGufford, Brandon T.Gufford, Brandon TThong, NancyThong, NancyThong, NancyThong, NancyThong, NancyDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayGaedigk, RogerGaedigk, RogerGaedigk, RogerGaedigk, RogerGaedigk, RogerPearce, Robin EPearce, Robin E.Pearce, Robin EPearce, Robin EPearce, Robin EGaedigk, AndreaGaedigk, AndreaGaedigk, AndreaGaedigk, AndreaGaedigk, AndreaLiu, YunlongLiu, YunlongLiu, YunlongLiu, YunlongLiu, YunlongSkaar, Todd CSkaar, Todd CSkaar, Todd CSkaar, Todd C and Skaar, Todd C.
Clinical Pharmacology & Therapeutics, vol. 104, (no. 1), pp. 138, July 2018. | Journal Article
2017
Clinical and educational impact of pharmacogenomics testing: a case series from the INGENIOUS trial
Pierson, Rebecca CPierson, Rebecca CPierson, Rebecca CPierson, Rebecca CGufford, Brandon TGufford, Brandon TGufford, Brandon TGufford, Brandon TDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayEadon, Michael TEadon, Michael TEadon, Michael T and Eadon, Michael T
Pharmacogenomics, vol. 18, (no. 9), pp. 841, 2017-May-01. | Journal Article
2016
Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers
Masters, Andrea RMasters, Andrea RGufford, Brandon TGufford, Brandon TLu, Jessica Bo LiLu, Jessica Bo LiMetzger, Ingrid FMetzger, Ingrid FJones, David RJones, David RDesta, Zeruesenay and Desta, Zeruesenay
The Journal of pharmacology and experimental therapeutics, vol. 358, (no. 2), pp. 238, 2016-08-00. | Journal Article
 
Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo
Gufford, Brandon TGufford, Brandon TLu, Jessica Bo LiLu, Jessica Bo LiMetzger, Ingrid FMetzger, Ingrid FJones, David RJones, David RDesta, Zeruesenay and Desta, Zeruesenay
Drug metabolism and disposition: the biological fate of chemicals, vol. 44, (no. 4), pp. 553, 2016-Apr. | Journal Article
2015
Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product-Drug Interaction
Gufford, Brandon TGufford, Brandon TChen, GangChen, GangVergara, Ana GVergara, Ana GLazarus, PhilipLazarus, PhilipOberlies, Nicholas HOberlies, Nicholas HPaine, Mary F and Paine, Mary F
Drug metabolism and disposition: the biological fate of chemicals, vol. 43, (no. 9), pp. 1359, 2015-Sep. | Journal Article
2013
Semisynthesis, cytotoxicity, antiviral activity, and drug interaction liability of 7-O-methylated analogues of flavonolignans from milk thistle
Althagafy, Hanan SAlthagafy, Hanan SGraf, Tyler NGraf, Tyler NSy-Cordero, Arlene ASy-Cordero, Arlene AGufford, Brandon TGufford, Brandon TPaine, Mary FPaine, Mary FWagoner, JessicaWagoner, JessicaPolyak, Stephen JPolyak, Stephen JCroatt, MitchellCroatt, Mitchell POberlies, Nicholas H and Oberlies, Nicholas H
Bioorganic & Medicinal Chemistry, vol. 21, (no. 13), pp. 3926, 2013-07-01. | Journal Article