39 Publications (Page 1 of 2)
2019
Constructing Kinetically Controlled Denaturation Isotherms of Folded Proteins Using Denaturant-Pulse Chaperonin Binding
O'Neil, Pierce T⋅O'Neil, Pierce T⋅Machen, Alexandra J⋅Machen, Alexandra J⋅Thompson, Jackie A⋅Thompson, Jackie A⋅Wang, Wei⋅Wang, Wei⋅Hoang, Quyen Q⋅Hoang, Quyen Q⋅Baldwin, Michael R⋅Baldwin, Michael R⋅Khar, Karen R⋅Khar, Karen R⋅Karanicolas, John⋅Karanicolas, John⋅Fisher, Mark T and Fisher, Mark T
Methods in molecular biology (Clifton, N.J.), vol. 1873, pp. 304, 2019-00-00. | Journal Article
 
Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections
Washburn, Alex⋅Washburn, Alex⋅Washburn, Alex⋅Abdeen, Sanofar⋅Abdeen, Sanofar⋅Abdeen, Sanofar⋅Ovechkina, Yulia⋅Ovechkina, Yulia⋅Ovechkina, Yulia⋅Ray, Anne-Marie⋅Ray, Anne-Marie⋅Ray, Anne-Marie⋅Stevens, Mckayla⋅Stevens, Mckayla⋅Stevens, Mckayla⋅Chitre, Siddhi⋅Chitre, Siddhi⋅Chitre, Siddhi⋅Sivinski, Jared⋅Sivinski, Jared⋅Sivinski, Jared⋅Park, Yangshin⋅Park, Yangshin⋅Park, Yangshin⋅Johnson, James⋅Johnson, James⋅Johnson, Steven M⋅Johnson, James⋅Hoang, Quyen Q⋅Hoang, Quyen Q⋅Hoang, Quyen Q⋅Chapman, Eli⋅Chapman, Eli⋅Chapman, Eli⋅Parish, Tanya⋅Parish, Tanya⋅Parish, Tanya⋅Johnson, Steven M and Johnson, Steven M
Bioorganic & Medicinal Chemistry Letters, vol. 29, (no. 13), pp. 1672, 2019-07-01. | Journal Article
 
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules
Stevens, Mckayla⋅Stevens, Mckayla⋅Abdeen, Sanofar⋅Abdeen, Sanofar⋅Salim, Nilshad⋅Salim, Nilshad⋅Ray, Anne-Marie⋅Ray, Anne-Marie⋅Washburn, Alex⋅Washburn, Alex⋅Chitre, Siddhi⋅Chitre, Siddhi⋅Sivinski, Jared⋅Sivinski, Jared⋅Park, Yangshin⋅Park, Yangshin⋅Hoang, Quyen Q⋅Hoang, Quyen Q⋅Chapman, Eli⋅Chapman, Eli⋅Johnson, Steven M and Johnson, Steven M
Bioorganic & Medicinal Chemistry Letters, vol. 29, (no. 9), pp. 1112, 2019-05-01. | Journal Article
 
Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics
Wu, Chun-Xiang⋅Wu, Chun-Xiang⋅Liao, Jingling⋅Liao, Jingling⋅Park, Yangshin⋅Park, Yangshin⋅Reed, Xylena⋅Reed, Xylena⋅Engel, Victoria A⋅Engel, Victoria A⋅Hoang, Neo C⋅Hoang, Neo C⋅Takagi, Yuichiro⋅Takagi, Yuichiro⋅Johnson, Steven M⋅Johnson, Steven M⋅Wang, Mu⋅Wang, Mu⋅Federici, Mark⋅Federici, Mark⋅Nichols, R Jeremy⋅Nichols, R Jeremy⋅Sanishvili, Ruslan⋅Sanishvili, Ruslan⋅Cookson, Mark R⋅Cookson, Mark R⋅Hoang, Quyen Q and Hoang, Quyen Q
The Journal of biological chemistry, vol. 294, (no. 15), pp. 5913, 2019-04-12. | Journal Article
 
Point-of-use robotic sensors for simultaneous pressure detection and chemical analysis
Amit, Moran⋅Moran, Amit⋅Mishra, Rupesh K⋅Mishra, Rupesh K⋅Hoang, Quyen⋅Hoang, Quyen⋅Galan, Aida Martin⋅Wang, Joseph⋅Wang, Joseph and Ng, Tse Nga
Materials Horizons, vol. 6, (no. 3), pp. 611, 2019-03-18. | Journal Article
 
Point-of-use robotic sensors for simultaneous pressure detection and chemical analysisElectronic supplementary information (ESI) available. See DOI: 10.1039/c8mh01412d
Amit, Moran⋅Mishra, Rupesh K⋅Hoang, Quyen⋅Galan, Aida Martin⋅Wang, Joseph and Ng, Tse Nga
(no. 3), pp. 611, 20190318. | Journal Article
 
The Parkinson's disease–associated mutation N1437H impairs conformational dynamics in the G domain of LRRK2
Huang, Xiaorong⋅Wu, Chunxiang⋅Park, Yangshin⋅Long, Xuwei⋅Hoang, Quyen Q and Liao, Jingling
The FASEB Journal, vol. 33, (no. 4), pp. 4823, April 2019. | Journal Article
2018
Discovery and Optimization of Inhibitors of the Parkinson’s Disease Associated Protein DJ‑1
Tashiro, Shinya⋅Caaveiro, Jose M. M⋅Nakakido, Makoto⋅Tanabe, Aki⋅Nagatoishi, Satoru⋅Tamura, Yasushi⋅Matsuda, Noriyuki⋅Liu, Dali⋅Hoang, Quyen Q and Tsumoto, Kouhei
ACS Chemical Biology, vol. 13, (no. 9), pp. 2793, 20180921. | Journal Article
 
Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus
Kunkle, Trent⋅Kunkle, Trent⋅Abdeen, Sanofar⋅Abdeen, Sanofar⋅Salim, Nilshad⋅Salim, Nilshad⋅Ray, Anne-Marie⋅Ray, Anne-Marie⋅Stevens, Mckayla⋅Stevens, Mckayla⋅Ambrose, Andrew J⋅Ambrose, Andrew J⋅Victorino, José⋅Victorino, José⋅Park, Yangshin⋅Park, Yangshin⋅Hoang, Quyen Q⋅Hoang, Quyen Q⋅Chapman, Eli⋅Chapman, Eli⋅Johnson, Steven M and Johnson, Steven M
Journal of Medicinal Chemistry, vol. 61, (no. 23), pp. 10664, 20181213. | Journal Article
 
Roco Proteins and the Parkinson’s Disease-Associated LRRK2
Liao, Jingling and Hoang, Quyen
International Journal of Molecular Sciences, vol. 19, (no. 12), pp. 4074, 2018-12-17. | Journal Article
 
Root-specific expression of defensin in transgenic tobacco results in enhanced resistance against Phytophthora parasitica var. nicotianae
Lee, Hyun-Hwa⋅Kim, Jin-Sol⋅Hoang, Quyen⋅Kim, Jeong-Il and Kim, Young
European Journal of Plant Pathology, vol. 151, (no. 3), pp. 823, 20180700. | Journal Article
 
Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA)
Abdeen, Sanofar⋅Abdeen, Sanofar⋅Abdeen, Sanofar⋅Kunkle, Trent⋅Kunkle, Trent⋅Kunkle, Trent⋅Salim, Nilshad⋅Salim, Nilshad⋅Salim, Nilshad⋅Ray, Anne-Marie⋅Ray, Anne-Marie⋅Ray, Anne-Marie⋅Mammadova, Najiba⋅Mammadova, Najiba⋅Mammadova, Najiba⋅Summers, Corey⋅Summers, Corey⋅Summers, Corey⋅Stevens, Mckayla⋅Stevens, Mckayla⋅Stevens, Mckayla⋅Ambrose, Andrew J⋅Ambrose, Andrew J⋅Ambrose, Andrew⋅Park, Yangshin⋅Park, Yangshin⋅Park, Yangshin⋅Schultz, Peter G⋅Schultz, Peter G⋅Schultz, Peter G⋅Horwich, Arthur L⋅Horwich, Arthur L⋅Horwich, Arthur L⋅Hoang, Quyen Q⋅Hoang, Quyen⋅Hoang, Quyen Q⋅Chapman, Eli⋅Chapman, Eli⋅Chapman, Eli⋅Johnson, Steven M⋅Johnson, Steven M and Johnson, Steven M
Journal of Medicinal Chemistry, vol. 61, (no. 16), pp. 7357, 20180823. | Journal Article
2017
Combating Parkinson's disease-associated toxicity by modulating proteostasis.
Park, Yangshin and Hoang, Quyen Q
Proceedings of the National Academy of Sciences of the United States of America, vol. 114, (no. 5), pp. 803-804, January 31, 2017. | Journal Article
 
The reduced reversible phase transition field of lead–free Bi–based ceramic composites by adding nonergodic relaxor
Dinh, Thi Hinh⋅Tran, Vu Diem Ngoc⋅Nguyen, Thi Thao⋅Hoang, Quyen Thi Ngoc⋅Han, Hyoung–Su and Lee, Jae–Shin
Ceramics International, vol. 43, (no. 18), pp. 17166, 2017-12-15. | Journal Article
2016
Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein a-synuclein
Wang, Wei⋅Nguyen, Linh⋅Burlak, Christopher⋅Chegini, Fariba⋅Guo, Feng⋅Chataway, Tim⋅Ju, Shulin⋅Fisher, Oriana⋅Miller, David⋅Datta, Debajyoti⋅Wu, Fang⋅Wu, Chun-Xiang⋅Landeru, Anuradha⋅Wells, James⋅Cookson, Mark⋅Boxer, Matthew⋅Thomas, Craig⋅Gai, Wei⋅Ringe, Dagmar⋅Petsko, Gregory and Hoang, Quyen
Proceedings of the National Academy of Sciences of the United States of America, vol. 113, (no. 34), pp. 9587, 20160823. | Journal Article
 
Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein.
Wang, Wei⋅Nguyen, Linh T T⋅Burlak, Christopher⋅Chegini, Fariba⋅Guo, Feng⋅Chataway, Tim⋅Ju, Shulin⋅Fisher, Oriana S⋅Miller, David W⋅Datta, Debajyoti⋅Wu, Fang⋅Wu, Chun-Xiang⋅Landeru, Anuradha⋅Wells, James A⋅Cookson, Mark R⋅Boxer, Matthew B⋅Thomas, Craig J⋅Gai, Wei Ping⋅Ringe, Dagmar⋅Petsko, Gregory A and Hoang, Quyen Q
Proceedings of the National Academy of Sciences of the United States of America, vol. 113, (no. 34), pp. 9587-9592, August 23, 2016. | Journal Article
 
Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites.
Liu, Ce Feng⋅Brandt, Gabriel S⋅Hoang, Quyen Q⋅Naumova, Natalia⋅Lazarevic, Vanja⋅Hwang, Eun Sook⋅Dekker, Job⋅Glimcher, Laurie H⋅Ringe, Dagmar and Petsko, Gregory A
Proceedings of the National Academy of Sciences of the United States of America, vol. 113, (no. 43), pp. E6572-E6581, October 25, 2016. | Journal Article
 
Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy.
Bassil, Fares⋅Fernagut, Pierre-Olivier⋅Bezard, Erwan⋅Pruvost, Alain⋅Leste-Lasserre, Thierry⋅Hoang, Quyen Q⋅Ringe, Dagmar⋅Petsko, Gregory A and Meissner, Wassilios G
Proceedings of the National Academy of Sciences of the United States of America, vol. 113, (no. 34), pp. 9593-9598, August 23, 2016. | Journal Article
2015
Structural and Biochemical Characterization of AidC, a Quorum-Quenching Lactonase with Atypical Selectivity.
Mascarenhas, Romila⋅Thomas, Pei W⋅Wu, Chun-Xiang⋅Nocek, Boguslaw P⋅Hoang, Quyen Q⋅Liu, Dali and Fast, Walter
Biochemistry, vol. 54, (no. 28), pp. 4342-4353, July 21, 2015. | Journal Article
2014
Parkinson disease-associated mutation R1441H in LRRK2 prolongs the "active state" of its GTPase domain
Liao, Jingling⋅Wu, Chun-Xiang⋅Burlak, Christopher⋅Zhang, Sheng⋅Sahm, Heather⋅Wang, Mu⋅Zhang, Zhong Yin⋅Vogel, Kurt W⋅Federici, Mark⋅Riddle, Steve M⋅Nichols, R. J⋅Liu, Dali⋅Cookson, Mark R⋅Stone, Todd A and Hoang, Quyen
Proceedings of the National Academy of Sciences of the United States of America, vol. 111, (no. 11), Mar 18, 2014. | Journal Article
 
Pathway for Parkinson disease.
Hoang, Quyen Q
Proceedings of the National Academy of Sciences of the United States of America, vol. 111, (no. 7), pp. 2402-2403, February 18, 2014. | Journal Article
 
Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated [alpha]-synuclein
Oh, Misook⋅Lee, Ji⋅Wang, Wei⋅Lee, Hui⋅Lee, Woo⋅Burlak, Christopher⋅Im, Wonpil⋅Hoang, Quyen and Lim, Hyun-Suk
Proceedings of the National Academy of Sciences of the United States of America, vol. 111, (no. 30), pp. 11007, 20140729. | Journal Article
 
Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated α-synuclein.
Oh, Misook⋅Lee, Ji H⋅Wang, Wei⋅Lee, Hui S⋅Lee, Woo S⋅Burlak, Christopher⋅Im, Wonpil⋅Hoang, Quyen Q and Lim, Hyun Suk
Proceedings of the National Academy of Sciences of the United States of America, vol. 111, (no. 30), pp. 11007-12, 2014/Jul/29. | Journal Article
 
Thermodynamic and structural characterization of the specific binding of Zn(II) to human protein DJ-1.
Tashiro, Shinya⋅Caaveiro, Jose M M⋅Wu, Chun-Xiang⋅Hoang, Quyen Q and Tsumoto, Kouhei
Biochemistry, vol. 53, (no. 14), pp. 2218-2220, April 15, 2014. | Journal Article
 
Xenotransplantation literature update, May-June 2014.
Burlak, Christopher and Hoang, Quyen Q
Xenotransplantation, vol. 21, (no. 4), pp. 392-395. | Journal Article