103 Publications (Page 4 of 5)
2005
Ab Initio QM/MM Study of Class A β-Lactamase Acylation:  Dual Participation of Glu166 and Lys73 in a Concerted Base Promotion of Ser70
Meroueh, Samy O⋅Fisher, Jed F⋅Schlegel, H. Bernhard and Mobashery, Shahriar
Journal of the American Chemical Society, vol. 127, (no. 44), pp. 15407, 20051109. | Journal Article
 
Bacterial resistance to beta-lactam antibiotics: Compelling opportunism, compelling opportunity
Fisher, Jed F⋅Meroueh, Samy and Mobashery, Shahriar
Chemical Reviews, vol. 105, (no. 2), pp. 395-424, Feb 2005. | Journal Article
 
Bacterial Resistance to β-Lactam Antibiotics:  Compelling Opportunism, Compelling Opportunity
Fisher, Jed F⋅Meroueh, Samy O and Mobashery, Shahriar
Chemical Reviews, vol. 105, (no. 2), pp. 424, 20050209. | Journal Article
 
Bacterial Resistance to β‐Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity
Fisher, Jed F⋅Meroueh, Samy O and Mobashery, Shahriar
ChemInform, vol. 36, (no. 24), pp. no, June 14, 2005. | Journal Article
 
Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase.
Toth, Marta⋅Osenkowski, Pamela⋅Hesek, Dusan⋅Brown, Stephen⋅Meroueh, Samy⋅Sakr, Wael⋅Mobashery, Shahriar and Fridman, Rafael
The Biochemical journal, vol. 387, (no. Pt 2), pp. 497-506, 2005/Apr/15. | Journal Article
 
Computational investigation of irreversible inactivation of the zinc-dependent protease carboxypeptidase A.
Cross, Jason B⋅Vreven, Thom⋅Meroueh, Samy⋅Mobashery, Shahriar and Schlegel, H. B
The journal of physical chemistry. B, vol. 109, (no. 10), pp. 4761-9, 2005/Mar/17. | Journal Article
 
Design, synthesis, and evaluation of a mechanism-based inhibitor for gelatinase A.
Ikejiri, Masahiro⋅Bernardo, M. M⋅Meroueh, Samy⋅Brown, Stephen⋅Chang, Mayland⋅Fridman, Rafael A and Mobashery, Shahriar
The Journal of organic chemistry, vol. 70, (no. 14), pp. 5709-12, 2005/Jul/8. | Journal Article
 
Lysine carboxylation in proteins: OXA-10 beta-lactamase.
Li, Jie⋅Cross, Jason B⋅Vreven, Thom⋅Meroueh, Samy⋅Mobashery, Shahriar and Schlegel, H B
Proteins, vol. 61, (no. 2), pp. 246-57, 2005/Nov/1. | Journal Article
 
Mutational and Structural Analyses of the Hinge Region of Membrane Type 1-Matrix Metalloproteinase and Enzyme Processing.
Osenkowski, Pamela⋅Meroueh, Samy⋅Pavel, Dumitru⋅Mobashery, Shahriar and Fridman, Rafael A
Journal of biological chemistry., vol. 280, (no. 28), pp. 26160-26168, 2005. | Journal Article
 
Synthesis of chiral 2-(4-phenoxyphenylsulfonylmethyl)thiiranes as selective gelatinase inhibitors.
Lee, Mijoon⋅Bernardo, M. M⋅Meroueh, Samy⋅Brown, Stephen⋅Fridman, Rafael and Mobashery, Shahriar
Organic letters, vol. 7, (no. 20), pp. 4463-5, 2005/Sep/29. | Journal Article
2004
Fluorinated aminoglycosides and their mechanistic implication for aminoglycoside 3'-phosphotransferases from Gram-negative bacteria.
Kim, Choonkeun⋅Haddad, Jalal⋅Vakulenko, Sergei⋅Meroueh, Samy⋅Wu, Yan⋅Yan, Honggao and Mobashery, Shahriar
Biochemistry, vol. 43, (no. 9), pp. 2373-83, 2004/Mar/9. | Journal Article
 
Quest for selectivity in inhibition of matrix metalloproteinases.
Brown, Stephen⋅Meroueh, Samy⋅Fridman, Rafael A and Mobashery, Shahriar
Current topics in medicinal chemistry, vol. 4, (no. 12), pp. 1227-38, 2004. | Journal Article
 
Strategy in inhibition of cathepsin B, a target in tumor invasion and metastasis.
Lim, In T⋅Meroueh, Samy⋅Lee, Mijoon⋅Heeg, Mary J and Mobashery, Shahriar
Journal of the American Chemical Society, vol. 126, (no. 33), pp. 10271-7, 2004/Aug/25. | Journal Article
 
The importance of a critical protonation state and the fate of the catalytic steps in class A beta-lactamases and penicillin-binding proteins.
Golemi-Kotra, Dasantila⋅Meroueh, Samy O⋅Kim, Choonkeun⋅Vakulenko, Sergei B⋅Bulychev, Alexey⋅Stemmler, Ann J⋅Stemmler, Timothy L and Mobashery, Shahriar
The Journal of biological chemistry, vol. 279, (no. 33), pp. 34665-34673, August 13, 2004. | Journal Article
 
The Importance of a Critical Protonation State and the Fate of the Catalytic Steps in Class A beta -Lactamases and Penicillin-binding Proteins
Golemi Kotra, Dasantila⋅Meroueh, Samy⋅Kim, Choonkeun⋅Vakulenko, Sergei⋅Bulychev, Alexey⋅Stemmler, Ann J⋅Stemmler, Timothy L and Mobashery, Shahriar
Journal of Biological Chemistry, vol. 279, (no. 33), pp. 34665-34673, 2004. | Journal Article
 
The Importance of a Critical Protonation State and the Fate of the Catalytic Steps in Class A β-Lactamases and Penicillin-binding Proteins
Golemi-Kotra, Dasantila⋅Meroueh, Samy O⋅Kim, Choonkeun⋅Vakulenko, Sergei B⋅Bulychev, Alexey⋅Stemmler, Ann J⋅Stemmler, Timothy L and Mobashery, Shahriar
The Journal of biological chemistry, vol. 279, (no. 33), pp. 34673, 2004-Aug-13. | Journal Article
 
X-ray crystal structure of the acylated beta-lactam sensor domain of BlaR1 from Staphylococcus aureus and the mechanism of receptor activation for signal transduction.
Birck, Catherine⋅Cha, Joo Y⋅Cross, Jason⋅Schulze-Briese, Clemens⋅Meroueh, Samy⋅Schlegel, H B⋅Mobashery, Shahriar and Samama, Jean-Pierre
Journal of the American Chemical Society, vol. 126, (no. 43), pp. 13945-7, 2004/Nov/3. | Journal Article
 
X-ray crystal structure of the acylated beta-lactem sensor domain of BlaR1 from staphylococcus aureus and the mechanism of receptor activation for signal transduction
Birck, Catherine⋅Cha, Joo⋅Cross, Jason⋅Schulze-Briese, Clemens⋅Meroueh, Samy⋅Schlegel, Bernhard⋅Mobashery, Shahriar and Samama, Jean-Pierre
Journal of the American Chemical Society, vol. 126, (no. 43), pp. 13945, 20041103. | Journal Article
 
X-ray Crystal Structure of the Acylated β-Lactam Sensor Domain of BlaR1 from Staphylococcus aureus and the Mechanism of Receptor Activation for Signal Transduction
Birck, Catherine⋅Cha, Joo Young⋅Cross, Jason⋅Schulze-Briese, Clemens⋅Meroueh, Samy O⋅Schlegel, H. Bernhard⋅Mobashery, Shahriar and Samama, Jean-Pierre
Journal of the American Chemical Society, vol. 126, (no. 43), pp. 13947, 20041103. | Journal Article
2003
A Dynamic Structure for the Acyl-Enzyme Species of the Antibiotic Aztreonam with the Citrobacter freundii beta -Lactamase Revealed by Infrared Spectroscopy and Molecular Dynamics Simulations
Wilkinson, A-S⋅Bryant, PK⋅Meroueh, Samy⋅Page, MGP⋅Mobashery, Shahriar and Wharton, C. W
Biochemistry (Washington), vol. 42, (no. 7), pp. 1950-1957, 2003. | Journal Article
 
Cell surface association of matrix metalloproteinase-9 (gelatinase B)
Fridman, Rafael A⋅Toth, Marta⋅Chvyrkova, Irina⋅Meroueh, Samy and Mobashery, Shahriar
Cancer and Metastasis Reviews, vol. 22, (no. 2/3), pp. 153, Jun-Sep 2003. | Journal Article
 
Cell surface association of matrix metalloproteinase-9 (gelatinase B).
Fridman, Rafael A⋅Toth, Marta⋅Chvyrkova, Irina⋅Meroueh, Samy and Mobashery, Shahriar
Cancer metastasis reviews. , vol. 22, (no. 2-3), pp. 153-66, 2003 Jun-Sep. | Journal Article
 
Resistance to beta -Lactam Antibiotics and Its Mediation by the Sensor Domain of the Transmembrane BlaR Signaling Pathway in Staphylococcus aureus
Golemi Kotra, Dasantila⋅Cha, JY⋅Meroueh, Samy⋅Vakulenko, Sergei and Mobashery, Shahriar
Journal of Biological Chemistry, vol. 278, (no. 20), pp. [na], 2003. | Journal Article
 
Structural aspects for evolution of beta-lactamases from penicillin-binding proteins.
Meroueh, Samy⋅Minasov, George⋅Lee, Wenlin⋅Shoichet, Brian K and Mobashery, Shahriar
Journal of the American Chemical Society, vol. 125, (no. 32), pp. 9612-8, 2003/Aug/13. | Journal Article
 
Structural Aspects for Evolution of β-Lactamases from Penicillin-Binding Proteins
Meroueh, Samy O⋅Minasov, George⋅Lee, Wenlin⋅Shoichet, Brian K and Mobashery, Shahriar
Journal of the American Chemical Society, vol. 125, (no. 32), pp. 9618, 20030813. | Journal Article