22 Publications
2020
Classification of the Molecular Defects Associated with Pathogenic Variants of the SLC6A8 Creatine Transporter
Salazar, Martin D⋅Salazar, Martin D⋅Zelt, Nathan B⋅Zelt, Nathan B⋅Saldivar, Robert⋅Saldivar, Robert⋅Kuntz, Charles P⋅Kuntz, Charles P⋅Chen, Sheng⋅Chen, Sheng⋅Penn, Wesley D⋅Penn, Wesley D⋅Bonneau, Richard⋅Bonneau, Richard⋅Koehler Leman, Julia⋅Koehler Leman, Julia⋅Schlebach, Jonathan P and Schlebach, Jonathan P
Biochemistry, vol. 59, (no. 13), pp. 1377, 2020-Apr-07. | Journal Article
 
Cotranslational folding stimulates programmed ribosomal frameshifting in the alphavirus structural polyprotein
Harrington, Haley R⋅Harrington, Haley R⋅Zimmer, Matthew H⋅Zimmer, Matthew H⋅Chamness, Laura M⋅Chamness, Laura M⋅Nash, Veronica⋅Nash, Veronica⋅Penn, Wesley D⋅Penn, Wesley D⋅Miller, 3rd, Thomas F⋅Miller, 3rd, Thomas F⋅Mukhopadhyay, Suchetana⋅Mukhopadhyay, Suchetana⋅Schlebach, Jonathan P and Schlebach, Jonathan P
The Journal of biological chemistry, vol. 295, (no. 20), pp. 6808, 2020-May-15. | Journal Article
 
Probing biophysical sequence constraints within the transmembrane domains of rhodopsin by deep mutational scanning
Penn, Wesley D⋅Penn, Wesley D.⋅McKee, Andrew G.⋅McKee, Andrew G⋅Kuntz, Charles P⋅Kuntz, Charles P.⋅Woods, Hope⋅Woods, Hope⋅Nash, Veronica⋅Nash, Veronica⋅Gruenhagen, Timothy C⋅Gruenhagen, Timothy C.⋅Roushar, Francis J⋅Roushar, Francis J.⋅Chandak, Mahesh⋅Chandak, Mahesh⋅Hemmerich, Chris⋅Hemmerich, Chris⋅Rusch, Douglas B⋅Rusch, Douglas B.⋅Meiler, Jens⋅Meiler, Jens⋅Schlebach, Jonathan P. and Schlebach, Jonathan P
Science advances, vol. 6, (no. 10), pp. eaay7505, 2020-03-00. | Journal Article
2019
Contribution of Cotranslational Folding Defects to Membrane Protein Homeostasis
Roushar, Francis J⋅Roushar, Francis J⋅Roushar, Francis J⋅Gruenhagen, Timothy C⋅Gruenhagen, Timothy C⋅Gruenhagen, Timothy C⋅Penn, Wesley D⋅Penn, Wesley D⋅Penn, Wesley D⋅Li, Bian⋅Li, Bian⋅Li, Bian⋅Meiler, Jens⋅Meiler, Jens⋅Meiler, Jens⋅Jastrzebska, Beata⋅Jastrzebska, Beata⋅Jastrzebska, Beata⋅Schlebach, Jonathan P⋅Schlebach, Jonathan P and Schlebach, Jonathan P
Journal of the American Chemical Society, vol. 141, (no. 1), pp. 215, 2019-Jan-09. | Journal Article
 
Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis
Marinko, Justin T⋅Marinko, Justin T⋅Marinko, Justin T⋅Huang, Hui⋅Huang, Hui⋅Huang, Hui⋅Penn, Wesley D⋅Penn, Wesley D⋅Penn, Wesley D⋅Capra, John A⋅Capra, John A⋅Capra, John A⋅Schlebach, Jonathan P⋅Schlebach, Jonathan P⋅Schlebach, Jonathan P⋅Sanders, Charles R⋅Sanders, Charles R and Sanders, Charles R
Chemical reviews, vol. 119, (no. 9), pp. 5606, 2019-May-08. | Journal Article
 
Ions at the Interface: Pushing the pK of pHLIP
Schlebach, Jonathan P
Biophysical Journal, vol. 117, (no. 5), pp. 794, 2019-09-03. | Journal Article
2018
Bicelle size modulates the rate of bacteriorhodopsin folding
Gruenhagen, Timothy C⋅Gruenhagen, Timothy C⋅Ziarek, Joshua J⋅Ziarek, Joshua J⋅Schlebach, Jonathan P and Schlebach, Jonathan P
Protein Science, vol. 27, (no. 6), pp. 1112, 2018-06-00. | Journal Article
 
The Retinitis Pigmentosa-Linked Mutations in Transmembrane Helix 5 of Rhodopsin Disrupt Cellular Trafficking Regardless of Oligomerization State
Mallory, D Paul⋅Gutierrez, Elizabeth⋅Pinkevitch, Margaret⋅Klinginsmith, Christie⋅Comar, William D⋅Roushar, Francis J⋅Schlebach, Jonathan P⋅Smith, Adam W and Jastrzebska, Beata
Biochemistry, vol. 57, (no. 35), pp. 5201, 2018-09-04. | Journal Article
2017
Peripheral myelin protein 22 alters membrane architecture
Mittendorf, Kathleen F⋅Marinko, Justin T⋅Hampton, Cheri M⋅Ke, Zunlong⋅Hadziselimovic, Arina⋅Schlebach, Jonathan P⋅Law, Cheryl L⋅Li, Jun⋅Wright, Elizabeth R⋅Sanders, Charles R and Ohi, Melanie D
Science advances, vol. 3, (no. 7), pp. e1700220, 2017-07-00. | Journal Article
2016
A pH-Mediated Topological Switch within the N-Terminal Domain of Human Caveolin-3.
Kim, Ji-Hun⋅Schlebach, Jonathan P⋅Lu, Zhenwei⋅Peng, Dungeng⋅Reasoner, Kaitlyn C and Sanders, Charles R
Biophysical journal, vol. 110, (no. 11), pp. 2475-2485, June 7, 2016. | Journal Article
 
Topologically Diverse Human Membrane Proteins Partition to Liquid-Disordered Domains in Phase-Separated Lipid Vesicles.
Schlebach, Jonathan P⋅Schlebach, Jonathan P.⋅Barrett, Paul J⋅Barrett, Paul J.⋅Day, Charles A.⋅Day, Charles A⋅Kim, Ji Hun⋅Kim, Ji Hun⋅Kenworthy, Anne K⋅Kenworthy, Anne K.⋅Sanders, Charles R. and Sanders, Charles R
Biochemistry, vol. 55, (no. 7), pp. 985-988, February 23, 2016. | Journal Article
2015
Conformational Stability and Pathogenic Misfolding of the Integral Membrane Protein PMP22.
Schlebach, Jonathan P⋅Narayan, Malathi⋅Alford, Catherine⋅Mittendorf, Kathleen F⋅Carter, Bruce D⋅Li, Jun and Sanders, Charles R
Journal of the American Chemical Society, vol. 137, (no. 27), pp. 8758-8768, July 15, 2015. | Journal Article
 
Influence of Pathogenic Mutations on the Energetics of Translocon-Mediated Bilayer Integration of Transmembrane Helices
Schlebach, Jonathan and Sanders, Charles
Journal of Membrane Biology, vol. 248, (no. 3), pp. 371-381, Jun 2015. | Journal Article
 
The safety dance: biophysics of membrane protein folding and misfolding in a cellular context.
Schlebach, Jonathan P and Sanders, Charles R
Quarterly reviews of biophysics, vol. 48, (no. 1), pp. 1-34, February 2015. | Journal Article
2014
Bacteriorhodopsin Folds through a Poorly Organized Transition State
Schlebach, Jonathan P⋅Schlebach, Jonathan P⋅Woodall, Nicholas B⋅Woodall, Nicholas B⋅Bowie, James U⋅Bowie, James U⋅Park, Chiwook and Park, Chiwook
Journal of the American Chemical Society, vol. 136, (no. 47), pp. 16581, 2014-Nov-26. | Journal Article
 
Cholesterol Binding Drives Partitioning of the Amyloid Precursor C99 Protein Into Liquid Ordered Membrane Domains
Barrett, Paul J⋅Day, Charles A⋅Song, Yuanli⋅Schlebach, Jonathan P⋅Kenworthy, Anne K and Sanders, Charles R
Biophysical Journal, vol. 106, (no. 2), pp. 301a, 2014-01-28. | Journal Article
 
Modest effects of lipid modifications on the structure of caveolin-3.
Kim, Ji-Hun⋅Peng, Dungeng⋅Schlebach, Jonathan P⋅Hadziselimovic, Arina and Sanders, Charles R
Biochemistry, vol. 53, (no. 27), pp. 4320-2, 2014/Jul/15. | Journal Article
2013
Reversible folding of human peripheral myelin protein 22, a tetraspan membrane protein.
Schlebach, Jonathan P⋅Peng, Dungeng⋅Kroncke, Brett M⋅Mittendorf, Kathleen F⋅Narayan, Malathi⋅Carter, Bruce D and Sanders, Charles R
Biochemistry, vol. 52, (no. 19), pp. 3229-41, 2013/May/14. | Journal Article
2012
Revisiting the folding kinetics of bacteriorhodopsin.
Schlebach, Jonathan P⋅Cao, Zheng⋅Bowie, James U and Park, Chiwook
Protein science : a publication of the Protein Society, vol. 21, (no. 1), pp. 97-106, 2012/Jan. | Journal Article
 
Simplified proteomics approach to discover protein-ligand interactions.
Chang, Youngil⋅Schlebach, Jonathan P⋅Verheul, Ross A⋅VerHeul, Ross A and Park, Chiwook
Protein science : a publication of the Protein Society, vol. 21, (no. 9), pp. 1280-7, 2012/Sep. | Journal Article
 
Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state.
Cao, Zheng⋅Schlebach, Jonathan P⋅Park, Chiwook and Bowie, James U
Biochimica et biophysica acta, vol. 1818, (no. 4), pp. 1049-54, 2012/Apr. | Journal Article
2011
Probing membrane protein unfolding with pulse proteolysis.
Schlebach, Jonathan P⋅Kim, Moon Soo⋅Joh, Nathan H⋅Bowie, James U and Park, Chiwook
Journal of molecular biology, vol. 406, (no. 4), pp. 545-51, 2011/Mar/4. | Journal Article