30 Publications (Page 1 of 2)
2023
Real Time In vivo Analysis of Pancreatic Beta-cell Autophagic Flux Reveals Impairment Before Onset of Autoimmune Diabetes
2022
Stabilization protects islet integrity during respirometry in the Oroboros Oxygraph-2K analyzer
Crowder, Justin J.⋅Crowder, Justin J.⋅Zeng, Ziqian⋅Zeng, Ziqian⋅Novak, Alissa N.⋅Novak, Alissa N.⋅Alves, Nathan J.⋅Alves, Nathan J.⋅Linnemann, Amelia K. and Linnemann, Amelia K.
Islets, vol. 14, pp. 128–138. | Journal Article
2021
Beta Cell Autophagy in the Pathogenesis of Type 1 Diabetes
Muralidharan, Charanya and Linnemann, Amelia K
American Journal of Physiology-Endocrinology and Metabolism. | Journal Article
 
Fluorescently Conjugated Annular Fibrin Clot for Multiplexed Real-time Digestion Analysis
Zeng, Ziqian⋅Zeng, Ziqian⋅Chakravarthula, Tanmaye Nallan⋅Chakravarthula, Tanmaye Nallan⋅Muralidharan, Charanya⋅Muralidharan, Charanya⋅Hall, Abigail⋅Hall, Abigail⋅Linnemann, Amelia K⋅Linnemann, Amelia K⋅Alves, Nathan and Alves, Nathan
Journal of Materials Chemistry B. | Journal Article
 
Pancreatic beta cell autophagy is impaired in type 1 diabetes
Diabetologia. | Journal Article
2020
Intra-islet GLP-1, but not CCK, is necessary for β-cell function in mouse and human islets
de Souza, Arnaldo Henrique⋅Tang, Jiayin⋅Yadev, Amanjot Kaur⋅Saghafi, Samuel T⋅Kibbe, Carly R⋅Linnemann, Amelia K⋅Merrins, Matthew J and Davis, Dawn Belt
Scientific reports, vol. 10, (no. 1), pp. 2823, 2020-Feb-18. | Journal Article
 
Pancreatic Beta Cell Autophagy is Impaired in Type 1 Diabetes
 
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
Ast, Julia⋅Arvaniti, Anastasia⋅Fine, Nicholas H F⋅Nasteska, Daniela⋅Ashford, Fiona B⋅Stamataki, Zania⋅Koszegi, Zsombor⋅Bacon, Andrea⋅Jones, Ben J⋅Lucey, Maria A⋅Sasaki, Shugo⋅Brierley, Daniel I⋅Hastoy, Benoit⋅Tomas, Alejandra⋅D'Agostino, Giuseppe⋅Reimann, Frank⋅Lynn, Francis C⋅Reissaus, Christopher A⋅Linnemann, Amelia K⋅D'Este, Elisa⋅Calebiro, Davide⋅Trapp, Stefan⋅Johnsson, Kai⋅Podewin, Tom⋅Broichhagen, Johannes and Hodson, David J
Nature communications, vol. 11, (no. 1), pp. 467, 2020-01-24. | Journal Article
2019
194-OR: A Versatile Platform for Intravital Imaging of Biosensor-Labelled Beta Cells In Situ
REISSAUS, CHRISTOPHER A⋅TERSEY, SARAH A⋅DUNN, KEN W⋅Linnemann, Amelia K and MIRMIRA, RAGHAVENDRA
Diabetes, vol. 68, (no. Supplement 1), pp. 194, 2019-06-00. | Journal Article
 
197-OR: IL-6 Protects Pancreatic ß Cells from Oxidative Stress via NRF2 Mitochondrial Translocation and Mitophagy
MARASCO, MICHELLE⋅CONTEH, ABASS M⋅MURALIDHARAN, CHARANYA⋅PFEIFER, ELIZABETH and Linnemann, Amelia K
Diabetes, vol. 68, (no. Supplement 1), pp. 197, 2019-06-00. | Journal Article
 
A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo
Reissaus, Christopher A⋅Reissaus, Christopher A⋅Reissaus, Christopher A⋅Piñeros, Annie R⋅Piñeros, Annie R⋅Piñeros, Annie R⋅Twigg, Ashley N⋅Twigg, Ashley N⋅Twigg, Ashley N⋅Orr, Kara S⋅Orr, Kara S⋅Orr, Kara S⋅Conteh, Abass M⋅Conteh, Abass M⋅Conteh, Abass M⋅Martinez, Michelle M⋅Martinez, Michelle M⋅Martinez, Michelle M⋅Kamocka, Malgorzata M⋅Kamocka, Malgorzata M⋅Kamocka, Malgorzata M⋅Day, Richard N⋅Day, Richard N⋅Day, Richard N⋅Tersey, Sarah A⋅Tersey, Sarah A⋅Tersey, Sarah A⋅Mirmira, Raghavendra G⋅Mirmira, Raghavendra G⋅Mirmira, Raghavendra G⋅Dunn, Kenneth W⋅Dunn, Kenneth W⋅Dunn, Kenneth W⋅Linnemann, Amelia K⋅Linnemann, Amelia K and Linnemann, Amelia K
Scientific reports, vol. 9, (no. 1), pp. 11, 2019-06-11. | Journal Article
 
Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet β cells
Conteh, Abass M⋅Reissaus, Christopher A⋅Hernandez-Perez, Marimar⋅Nakshatri, Swetha⋅Anderson, Ryan M⋅Mirmira, Raghavendra G⋅Tersey, Sarah A and Linnemann, Amelia K
The Journal of biological chemistry, vol. 294, (no. 16), pp. 6620, 2019-04-19. | Journal Article
2018
An In Vivo Zebrafish Model for Interrogating ROS-Mediated Pancreatic β-Cell Injury, Response, and Prevention
Kulkarni, Abhishek A⋅Conteh, Abass M⋅Sorrell, Cody A⋅Mirmira, Anjali⋅Tersey, Sarah A⋅Mirmira, Raghavendra G⋅Linnemann, Amelia K and Anderson, Ryan M
Oxidative Medicine and Cellular Longevity, vol. 2018, pp. 8, 20180328. | Journal Article
 
Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response
Marasco, Michelle R⋅Conteh, Abass M⋅Reissaus, Christopher A⋅Cupit, 5th, John E⋅Appleman, Evan M⋅Mirmira, Raghavendra G and Linnemann, Amelia K
Diabetes, vol. 67, (no. 8), pp. 1588, 2018-08-00. | Journal Article
 
β-Cell Autophagy in Diabetes Pathogenesis
Marasco, Michelle R and Linnemann, Amelia K
Endocrinology, vol. 159, (no. 5), pp. 2141, 2018-05-01. | Journal Article
2017
Inhibition of 12/15-Lipoxygenase Protects Against β-Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes
Hernandez-Perez, Marimar⋅Hernandez-Perez, Marimar⋅Chopra, Gaurav⋅Chopra, Gaurav⋅Fine, Jonathan⋅Fine, Jonathan⋅Conteh, Abass M⋅Conteh, Abass M⋅Anderson, Ryan M⋅Anderson, Ryan M⋅Linnemann, Amelia K⋅Linnemann, Amelia K⋅Benjamin, Chanelle⋅Benjamin, Chanelle⋅Nelson, Jennifer B⋅Nelson, Jennifer B⋅Benninger, Kara S⋅Benninger, Kara S⋅Nadler, Jerry L⋅Nadler, Jerry L⋅Maloney, David J⋅Maloney, David J⋅Tersey, Sarah A⋅Tersey, Sarah A⋅Mirmira, Raghavendra G and Mirmira, Raghavendra G
Diabetes, vol. 66, (no. 11), pp. 2887, 2017-Nov. | Journal Article
 
Interleukin 6 protects pancreatic β cells from apoptosis by stimulation of autophagy
Linnemann, Amelia K⋅Blumer, Joseph⋅Marasco, Michelle R⋅Battiola, Therese J⋅Umhoefer, Heidi M⋅Han, Jee Young⋅Lamming, Dudley W and Davis, Dawn Belt
The FASEB Journal, vol. 31, (no. 9), pp. 4152, September 2017. | Journal Article
2016
Glucagon‐like peptide‐1 and cholecystokinin production and signaling in the pancreatic islet as an adaptive response to obesity
Linnemann, Amelia K⋅Linnemann, Amelia K⋅Davis, Dawn Belt and Davis, Dawn Belt
Journal of Diabetes Investigation, vol. 7, (no. S1), pp. 49, April 2016. | Journal Article
2015
Glucagon-Like Peptide-1 Regulates Cholecystokinin Production in β-Cells to Protect From Apoptosis
Linnemann, Amelia K⋅Linnemann, Amelia K⋅Neuman, Joshua C⋅Neuman, Joshua C⋅Battiola, Therese J⋅Battiola, Therese J⋅Wisinski, Jaclyn A⋅Wisinski, Jaclyn A⋅Kimple, Michelle E⋅Kimple, Michelle E⋅Davis, Dawn Belt and Davis, Dawn Belt
Molecular Endocrinology, vol. 29, (no. 7), pp. 987, 2015-7. | Journal Article
2014
Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes
Kimple, Michelle E⋅Kimple, Michelle E⋅Neuman, Joshua C⋅Neuman, Joshua C⋅Linnemann, Amelia K⋅Linnemann, Amelia K⋅Casey, Patrick J and Casey, Patrick J
Experimental & molecular medicine, vol. 46, (no. 6), pp. e102, 2014-Jun-20. | Journal Article
 
Pancreatic β-Cell Proliferation in Obesity
Linnemann, Amelia K⋅Linnemann, Amelia K⋅Baan, Mieke⋅Baan, Mieke⋅Davis, Dawn Belt and Davis, Dawn Belt
Advances in nutrition (Bethesda, Md.), vol. 5, (no. 3), pp. 288, 2014-May. | Journal Article
2013
Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line
Krautkramer, Kimberly A⋅Krautkramer, Kimberly⋅Linnemann, Amelia⋅Linnemann, Amelia K⋅Fontaine, Danielle A⋅Fontaine, Danielle⋅Whillock, Amy L⋅Whillock, Amy⋅Harris, Ted⋅Harris, Ted W⋅Schleis, Gregory J⋅Schleis, Gregory⋅Truchan, Nathan⋅Truchan, Nathan A⋅Marty-Santos, Leilani⋅Marty-Santos, Leilani⋅Lavine, Jeremy A⋅Lavine, Jeremy⋅Cleaver, Ondine⋅Cleaver, Ondine⋅Kimple, Michelle⋅Kimple, Michelle E⋅Davis, Dawn and Davis, Dawn B
American Journal of Physiology - Endocrinology and Metabolism, vol. 305, (no. 5), pp. 610, 2013-09-01. | Journal Article
2012
Autophagy Driven by a Master Regulator of Hematopoiesis
Kang, Yoon-A⋅Kang, Yoon-A⋅Sanalkumar, Rajendran⋅Sanalkumar, Rajendran⋅O'Geen, Henriette⋅O'Geen, Henriette⋅Linnemann, Amelia K⋅Linnemann, Amelia⋅Chang, Chan-Jung⋅Chang, Chan-Jung⋅Bouhassira, Eric E⋅Bouhassira, Eric⋅Farnham, Peggy J⋅Farnham, Peggy⋅Keles, Sunduz⋅Keles, Sunduz⋅Bresnick, Emery H and Bresnick, Emery
Molecular and Cellular Biology, vol. 32, (no. 1), pp. 239, 20120101. | Journal Article
2011
Genetic framework for GATA factor function in vascular biology
Linnemann, Amelia K⋅Linnemann, Amelia⋅O'Geen, Henriette⋅O'Geen, Henriette⋅Keles, Sunduz⋅Keles, Sunduz⋅Farnham, Peggy J⋅Farnham, Peggy⋅Bresnick, Emery H and Bresnick, Emery
Proceedings of the National Academy of Sciences of the United States of America, vol. 108, (no. 33), pp. 13646, 20110816. | Journal Article
 
The sperm nucleus: chromatin, RNA, and the nuclear matrix
Johnson, Graham⋅Johnson, Graham⋅Lalancette, Claudia⋅Lalancette, Claudia⋅Linnemann, Amelia⋅Linnemann, Amelia K⋅Leduc, Frédéric⋅Leduc, Frédéric⋅Boissonneault, Guylain⋅Boissonneault, Guylain⋅Krawetz, Stephen and Krawetz, Stephen A
Reproduction, vol. 141, (no. 1), pp. 36, 20110101. | Journal Article