18 Publications
2013
Inhibiting glycogen synthesis prevents Lafora disease in a mouse model.
Pederson, Bartholomew A⋅Pederson, Bartholomew A⋅Turnbull, Julie⋅Turnbull, Julie⋅Epp, Jonathan R⋅Epp, Jonathan R⋅Weaver, Staci A⋅Weaver, Staci A⋅Zhao, Xiaochu⋅Zhao, Xiaochu⋅Pencea, Nela⋅Pencea, Nela⋅Roach, Peter J⋅Roach, Peter J⋅Frankland, Paul W⋅Frankland, Paul W⋅Ackerley, Cameron A⋅Ackerley, Cameron A⋅Minassian, Berge A and Minassian, Berge
Annals of neurology, vol. 74, (no. 2), pp. 297-300, 2013/Aug. | Journal Article
2011
Brain glycogen supercompensation in the mouse after recovery from insulin-induced hypoglycemia
Canada, Sarah E⋅Weaver, Staci A⋅Sharpe, Shannon N and Pederson, Bartholomew A
Journal of Neuroscience Research, vol. 89, (no. 4), pp. 585-591, 2011. | Journal Article
2008
A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.
Savage, David A⋅Zhai, Lanmin⋅Ravikumar, Balasubramanian⋅Cheol, S.C.⋅Choi, Cheol S⋅Snaar, Johanna E⋅McGuire, Amanda C⋅Wou, Sung-Eun⋅Medina-Gomez, Gemma⋅Kim, Sheene⋅Bock, Cheryl B⋅Segvich, Dyann M⋅Vidal Puig, Antonio⋅Solanky, Bhavana⋅Wareham, Nicholas J⋅Deelchand, Dinesh⋅Shulman, Gerald I⋅Karpe, Fredrik⋅Taylor, Roy⋅Pederson, Bartholomew A⋅Roach, Peter J⋅O’Rahilly, S.⋅O'Rahilly, Stephen⋅Depaoli Roach, Anna A and DePaoli-Roach, A.A.
PLoS medicine, vol. 5, (no. 1), pp. e27, 2008/Jan/29. | Journal Article
2006
Gene expression profiling of mice with genetically modified muscle glycogen content.
Parker, Gretchen E⋅Parker, Gretchen E⋅Pederson, Bartholomew A⋅Pederson, Bartholomew A⋅Obayashi, Mariko⋅Obayashi, Mariko⋅Schroeder, Jill M⋅Schroeder, Jill M⋅Harris, Robert A⋅Harris, Robert A⋅Roach, Peter J and Roach, Peter J
The Biochemical journal, vol. 395, (no. 1), pp. 137-45, 2006/Apr/1. | Journal Article
2005
Exercise Capacity of Mice Genetically Lacking Muscle Glycogen Synthase: IN MICE, MUSCLE GLYCOGEN IS NOT ESSENTIAL FOR EXERCISE.
Pederson, Bartholomew A⋅Cope, Carlie R⋅Schroeder, Jill M⋅Smith, Micah W⋅Irimia, José M⋅Thurberg, Beth L⋅Depaoli Roach, Anna A and Roach, Peter J
Journal of biological chemistry., vol. 280, (no. 17), pp. 17260-17265, 2005. | Journal Article
 
Glucose Metabolism in Mice Lacking Muscle Glycogen Synthase
Pederson, Bartholomew A⋅Schroeder, Jill M⋅Parker, Gretchen E⋅Smith, Micah W⋅Depaoli Roach, Anna A and Roach, Peter J
Diabetes, vol. 54, (no. 12), pp. 3466-3473, 2005. | Journal Article
 
Mice with elevated muscle glycogen stores do not have improved exercise performance.
Pederson, Bartholomew A⋅Cope, Carlie R⋅Irimia, Jose M⋅Schroeder, Jill M⋅Thurberg, Beth L⋅Depaoli Roach, Anna A and Roach, Peter J
Biochemical and biophysical research communications, vol. 331, (no. 2), pp. 491-6, 2005/Jun/3. | Journal Article
2004
Abnormal cardiac development in the absence of heart glycogen.
Pederson, Bartholomew A⋅Chen, Hanying⋅Schroeder, Jill M⋅Shou, Weinian⋅DePaoli-Roach, Anna A⋅Depaoli Roach, Anna A and Roach, Peter J
Molecular and cellular biology, vol. 24, (no. 16), pp. 7179-87, 2004/Aug. | Journal Article
 
Abnormal Cardiac Development in the Absence of Heart Glycogen
Pederson, Bartholomew⋅Pederson, Bartholomew A⋅Chen, Hanying⋅Chen, Hanying⋅Schroeder, Jill⋅Schroeder, Jill M⋅Shou, Weinian⋅Shou, Weinian⋅DePaoli-Roach, Anna⋅Depaoli Roach, Anna A⋅Roach, Peter J and Roach, Peter
Molecular and Cellular Biology, vol. 24, (no. 15), pp. 7179-7187, 2004. | Journal Article
 
Glycogen synthase sensitivity to glucose-6-P is important for controlling glycogen accumulation in Saccharomyces cerevisiae.
Pederson, Bartholomew A⋅Wilson, Wayne A and Roach, Peter J
The Journal of biological chemistry, vol. 279, (no. 14), pp. 13764-8, 2004/Apr/2. | Journal Article
2003
Overexpression of glycogen synthase in mouse muscle results in less branched glycogen.
Pederson, Bartholomew A⋅Csitkovits, Anna G⋅Simon, Renee⋅Schroeder, Jill M⋅Wang, Wei⋅Skurat, Alexander V and Roach, Peter J
Biochemical and biophysical research communications, vol. 305, (no. 4), pp. 826-30, 2003/Jun/13. | Journal Article
2000
Regulation of glycogen synthase. Identification of residues involved in regulation by the allosteric ligand glucose-6-P and by phosphorylation.
Pederson, Bartholomew A⋅Cheng, C⋅Wilson, Wayne A and Roach, Peter J
The Journal of biological chemistry, vol. 275, (no. 36), pp. 27753-61, 2000/Sep/8. | Journal Article
1998
Effects of ionic strength and chloride ion on activities of the glucose-6-phosphatase system: regulation of the biosynthetic activity of glucose-6-phosphatase by chloride ion inhibition/deinhibition.
Pederson, Bartholomew A⋅Nordlie, M A⋅Foster, James D and Nordlie, R C
Archives of biochemistry and biophysics, vol. 353, (no. 1), pp. 141-51, 1998/May/1. | Journal Article
 
Histone II-A activates the glucose-6-phosphatase system without microsomal membrane permeabilization.
Pederson, Bartholomew A⋅Foster, James D and Nordlie, R C
Archives of biochemistry and biophysics, vol. 357, (no. 1), pp. 173-7, 1998/Sep/1. | Journal Article
 
Low-Km mannose-6-phosphatase as a criterion for microsomal integrity.
Pederson, Bartholomew A⋅Foster, J D and Nordlie, R C
Biochemistry and cell biology = Biochimie et biologie cellulaire, vol. 76, (no. 1), pp. 115-24, 1998. | Journal Article
 
The glucose-6-phosphatase system: Structural integrity and physiologic function (Dissertation)
Pederson, Bartholomew A (1998).
1997
Glucose-6-phosphatase structure, regulation, and function: an update.
Foster, James D⋅Pederson, Bartholomew A and Nordlie, R C
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), vol. 215, (no. 4), pp. 314-32, 1997/Sep. | Journal Article
1996
Inhibition of the glucose-6-phosphatase system by N-bromoacetylethanolamine phosphate, a potential affinity label for auxiliary proteins.
Foster, James D⋅Pederson, Bartholomew A and Nordlie, R C
Biochimica et biophysica acta, vol. 1297, (no. 2), pp. 244-54, 1996/Oct/17. | Journal Article