Expertise

Specialization:

  • Drug targeting, Cancer therapeutics, Imaging and therapy of autoimmune diseases, Infectious disease therapeutics

Research:

  • Ligand-targeted drug discovery and delivery, immunotherapies, and targeted disease imaging agents

Research Areas

  • Phase 3 human clinical trials of Malaria
  • Acceleration of bone fracture repair
  • Development of new therapies for malaria
  • Design of ligand-targeted drugs
  • Tumor-targeted dyes for fluorescence-guided surgery of cancer
  • Development of novel immunotherapies for cancer
  • Novel imaging and therapeutic agents for automimune diseases
  • Design of new therapies for sickle cell disease
  • Design of targeted anti-viral therapies
  • Targeted control of cell-based therapeutics
  • Drug targeting to the tumor microenvironment
  • Structural characterization of the human red blood cell membrane
  • Pharmacologic control of neurotransmitter transporters

Research:

  • Reprogramming of the Immune System
  • Cancer Therapeutics
  • Bone and Soft Tissue Regeneration
  • Therapies for infectious Diseases
  • Fluorescence Guided Surgery of Cancer
  • Treatment of Erythrocyte Diseases

Expertise:

  • Chemistry
Affiliations

Ralph C. Corley Distinguished Professor, Department of Chemistry, College of Science, Purdue University

Presidential Scholar, Department of Chemistry, College of Science, Purdue University

Ralph C. Corley Distinguished Professor, Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University

Bindley Bioscience Center, Discovery Park District, Office of Research, Purdue University

Indiana Center for Musculoskeletal Health, Centers and Institutes, Indiana University School of Medicine

Purdue Center for Cancer Research, Office of Research, Purdue University

Past Affiliations

Professor, Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University (past)

Ralph C. Corley Distinguished Professor, Department of Chemistry, College of Science, Purdue University Fort Wayne (past)

Professor, Department of Chemistry, College of Science, Purdue University Fort Wayne (past)

Ralph C. Corley Distinguished Professor, Purdue University Center for Cancer Research, Office of Research, Purdue University (past)

Director, Purdue University Center for Cancer Research, Office of Research, Purdue University (past)

Professor, Purdue University Center for Cancer Research, Office of Research, Purdue University (past)

J. F. Foster Distinguished Professor, Biochemistry

Assistant Professor, Purdue University

Associate Professor, Purdue University

Communities
Oncology, Pharmacology, Chemistry
Degrees
PhD, University of California, San Diego, Biochemistry, 1975
BS, Brigham Young University, Chemistry, 1971
Keywords
biotechnology cancer or carcinogenesis thrombosis drug design hematology membrane structure or function cell & developmental biology plant diseases or pathology biochemistry, proteins
Languages
German
Associations
American Society for Biochemistry and Molecular Biology
American Society of Hematology
American Society of Plant Biologists
Controlled Release Society
Red Cell Club