172 Publications (Page 1 of 7)
2024
Machine Learning-Based Prediction of Escitalopram and Sertraline Side Effects with Pharmacokinetic Data in Children and Adolescents.
Poweleit, Ethan AVaughn, Samuel EDesta, ZeruesenayDexheimer, Judith WStrawn, Jeffrey R and Ramsey, Laura B
Clinical pharmacology and therapeutics, January 31, 2024. | Journal Article
2023
Clinically important alterations in pharmacogene expression in histologically severe nonalcoholic fatty liver disease
Powell, Nicholas R.Liang, TiebingIpe, JosephCao, ShaSkaar, Todd C.Desta, ZeruesenayQian, Hui-RongEbert, Philip J.Chen, YuThomas, Melissa K. and Chalasani, Naga
Nature Communications, vol. 14, (no. 1), pp. 1474, 2023. | Journal Article
 
Multidisciplinary Approach to Deciphering Etoposide Infusion Reactions and Potential Role of Polyethersulfone Filter Membranes.
Miles, NicholasMasters, AndiDesta, ZeruesenayGoldman, Jennifer LSuppes, Sarah L and Tillman, Emma M
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG, vol. 28, (no. 7), pp. 643-648, 2023. | Journal Article
2022
Clinical Opportunities for Germline Pharmacogenetics and Management of Drug-Drug Interactions in Patients With Advanced Solid Cancers.
Shugg, TylerShugg, TylerShugg, TylerLy, Reynold C.Ly, Reynold CLy, Reynold CRowe, Elizabeth JRowe, Elizabeth JRowe, Elizabeth J.Philips, SantoshPhilips, SantoshPhilips, SantoshHyder, Mustafa A.Hyder, Mustafa AHyder, Mustafa ARadovich, MilanRadovich, MilanRadovich, MilanRosenman, Marc BRosenman, Marc B.Rosenman, Marc BPratt, Victoria MPratt, Victoria M.Pratt, Victoria MCallaghan, John TCallaghan, John T.Callaghan, John TDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenaySchneider, Bryan PSchneider, Bryan PSchneider, Bryan P.Skaar, Todd C.Skaar, Todd C and Skaar, Todd C
JCO precision oncology, vol. 6, pp. e2100312, February 2022. | Journal Article
 
Genome-wide association study of aromatase inhibitor discontinuation due to musculoskeletal symptoms.
Hertz, Daniel LDouglas, Julie AMiller, Robert MKidwell, Kelley MGersch, Christina LDesta, ZeruesenayStorniolo, Anna MariaStearns, VeredSkaar, Todd CHayes, Daniel FHenry, N Lynn and Rae, James M
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, July 1, 2022. | Journal Article
2021
Circulating miRNAs as Biomarkers for CYP2B6 Enzyme Activity.
Ipe, JosephIpe, JosephLi, RudongLi, RudongMetzger, Ingrid FMetzger, Ingrid FBo Li Lu, JessicaBo Li Lu, JessicaGufford, Brandon TGufford, Brandon TDesta, ZeruesenayDesta, ZeruesenayLiu, YunlongLiu, YunlongSkaar, Todd C and Skaar, Todd C
Clinical pharmacology and therapeutics, vol. 109, (no. 2), pp. 485-493, February 2021. | Journal Article
 
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing.
Lima, J.J.Lima, John JLima, John J.Lima, John JJJ, LimaThomas, C.D.Thomas, Cameron DThomas, Cameron DCD, ThomasThomas, Cameron D.Barbarino, JuliaBarbarino, J.Barbarino, JuliaJ, BarbarinoBarbarino, JuliaDesta, ZeruesenayDesta, ZeruesenayDesta, Z.Desta, ZeruesenayZ, DestaVan Driest, S.L.Van Driest, Sara LVan Driest, Sara LSL, Van DriestVan Driest, Sara L.El Rouby, NihalN, El RoubyEl Rouby, N.El Rouby, NihalEl Rouby, NihalJohnson, J.A.Johnson, Julie A.Johnson, Julie AJA, JohnsonJohnson, Julie ALH, CavallariCavallari, Larisa H.Cavallari, L.H.Cavallari, Larisa HCavallari, Larisa HShakhnovich, ValentinaV, ShakhnovichShakhnovich, V.Shakhnovich, ValentinaShakhnovich, ValentinaThacker, David LThacker, D.L.Thacker, David L.DL, ThackerThacker, David LScott, Stuart AScott, S.A.SA, Scottal.Scott, Stuart ASchwab, M.Schwab, MatthiasM, SchwabSchwab, MatthiasUppugunduri, Chakradhara Rao SUppugunduri, Chakradhara Rao ST, FurutaFormea, C.M.Formea, Christine MFormea, Christine MFranciosi, James PFranciosi, James PFranciosi, J.P.Sangkuhl, K.Sangkuhl, KatrinSangkuhl, KatrinGaedigk, A.Gaedigk, AndreaGaedigk, AndreaKlein, Teri EKlein, T.E.Klein, Teri EGammal, Roseann SGammal, Roseann SGammal, R.S.Furuta, T.Furuta, Takahisa and Furuta, Takahisa
Clinical pharmacology and therapeutics, vol. 109, (no. 6), pp. 1417-1423, June 2021. | Journal Article
 
Genome-wide association study of letrozole plasma concentrations identifies non-exonic variants that may affect CYP2A6 metabolic activity.
Hertz, Daniel LDouglas, Julie AKidwell, Kelley MGersch, Christina LDesta, ZeruesenayStorniolo, Ana-MariaStearns, VeredSkaar, Todd CHayes, Daniel FHenry, N Lynn and Rae, James M
Pharmacogenetics and genomics, vol. 31, (no. 5), pp. 116-123, July 1, 2021. | Journal Article
 
PharmVar GeneFocus: CYP2B6.
Desta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayEl-Boraie, AhmedEl-Boraie, AhmedEl-Boraie, AhmedGong, LiGong, LiGong, LiSomogyi, Andrew A.Somogyi, Andrew ASomogyi, Andrew A.Lauschke, Volker M.Lauschke, Volker MLauschke, Volker M.Dandara, ColletDandara, ColletDandara, ColletKlein, KathrinKlein, KathrinKlein, KathrinMiller, NeilMiller, Neil AMiller, NeilKlein, Teri E.Klein, Teri EKlein, Teri E.Tyndale, Rachel F.Tyndale, Rachel FTyndale, Rachel F.Whirl-Carrillo, Michelleal. and Gaedigk, Andrea
Clinical pharmacology and therapeutics, vol. 110, (no. 1), pp. 82-97, July 2021. | Journal Article
2020
Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor α.
Ingle, James NIngle, James NCairns, JunmeiCairns, JunmeiSuman, Vera JSuman, Vera JShepherd, Lois EShepherd, Lois EFasching, Peter AFasching, Peter AHoskin, Tanya LHoskin, Tanya LSingh, Ravinder JSingh, Ravinder JDesta, ZeruesenayDesta, ZeruesenayKalari, Krishna RKalari, Krishna REllis, Matthew JEllis, Matthew JGoss, Paul EGoss, Paul EChen, Bingshu EChen, Bingshu EVolz, BernhardVolz, BernhardBarman, PoulamiBarman, PoulamiCarlson, Erin ECarlson, Erin EHaddad, Tufia CHaddad, TufiaGoetz, Matthew PGoetz, Matthew PGoodnature, BarbaraGoodnature, BarbaraCuellar, Matthew ECuellar, Matthew EWalters, Michael AWalters, Michael ACorreia, CristinaCorreia, CristinaKaufmann, Scott HKaufmann, Scott HWeinshilboum, Richard MWeinshilboum, Richard MWang, Liewei and Wang, Liewei
Clinical cancer research : an official journal of the American Association for Cancer Research, February 25, 2020. | Journal Article
 
A randomized placebo-controlled trial of bupropion for Cancer-related fatigue: Study design and procedures
Jim, Heather S.LHoogland, Aasha IHan, Hyo SookCulakova, EvaHeckler, CharlesJanelsins, MichelleWilliams, Geoffrey CBower, JulienneCole, StephenDesta, ZeruesenayBabilonia, Margarita BobonisMorrow, Gary and Peppone, Luke
Contemporary Clinical Trials, vol. 91, pp. 105976, April 2020. | Journal Article
 
Escitalopram in Adolescents With Generalized Anxiety Disorder: A Double-Blind, Randomized, Placebo-Controlled Study.
Strawn, Jeffrey RMills, Jeffrey ASchroeder, HeidiMossman, Sarah AVarney, Sara TRamsey, Laura BPoweleit, Ethan ADesta, ZeruesenayCecil, Kim and DelBello, Melissa P
The Journal of clinical psychiatry, vol. 81, (no. 5), August 25, 2020. | Journal Article
 
Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers
Collins, Kimberly SCollins, Kimberly SCollins, Kimberly SCollins, Kimberly SCollins, Kimberly S.Metzger, Ingrid F.Metzger, Ingrid FMetzger, Ingrid FMetzger, Ingrid FMetzger, Ingrid FGufford, Brandon TGufford, Brandon T.Gufford, Brandon TGufford, Brandon TGufford, Brandon TLu, Jessica BLu, Jessica BLu, Jessica BLu, Jessica BLu, JessicaMedeiros, Elizabeth BMedeiros, Elizabeth BMedeiros, Elizabeth BMedeiros, Elizabeth B.Medeiros, Elizabeth BPratt, Victoria MPratt, Victoria M.Pratt, Victoria MPratt, Victoria MPratt, Victoria MSkaar, Todd CSkaar, Todd CSkaar, Todd CSkaar, Todd CSkaar, Todd C.Desta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, Zeruesenay and Desta, Zeruesenay
Drug Metabolism and Disposition, vol. 48, (no. 3), Mar 1, 2020. | Journal Article
 
Inhibitory Effects of Probenecid on Pharmacokinetics of Tenofovir Disoproxil Fumarate and Emtricitabine for On-Demand HIV Preexposure Prophylaxis.
Liu, Stephanie NGufford, Brandon TLu, Jessica Bo LiBushman, Lane RAnderson, Peter LBergstrom, Richard FDesta, Zeruesenay and Gupta, Samir K
Clinical pharmacology and therapeutics, vol. 107, (no. 5), pp. 1200-1208, May 2020. | Journal Article
 
Inhibitory Effects of Probenecid on Pharmacokinetics of Tenofovir Disoproxil Fumarate and Emtricitabine for On‐Demand HIV Preexposure Prophylaxis
Liu, Stephanie NLiu, Stephanie NLiu, Stephanie NGufford, Brandon TGufford, Brandon TGufford, Brandon TLu, Jessica Bo LiLu, Jessica Bo LiLu, Jessica Bo LiBushman, Lane RBushman, Lane RBushman, Lane RAnderson, Peter LAnderson, Peter LAnderson, Peter LBergstrom, Richard FBergstrom, Richard FBergstrom, Richard FDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayGupta, Samir KGupta, Samir K and Gupta, Samir K
Clinical Pharmacology & Therapeutics, vol. 107, (no. 5), pp. 1208, May 2020. | Journal Article
 
Methadone-Associated QT Interval Prolongation in Patients Undergoing Maintenance Therapy in an Urban Opioid Treatment Program.
Titus‐Lay, Erika N.Titus‐Lay, Erika N.Titus-Lay, Erika NJaynes, Heather A.Jaynes, Heather A.Jaynes, Heather ATomaselli Muensterman, ElenaTomaselli Muensterman, ElenaTomaselli Muensterman, ElenaWalroth, Todd A.Walroth, Todd AWalroth, Todd A.Ott, Carol A.Ott, Carol AOtt, Carol A.Desta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayWilliams, GabrielaWilliams, GabrielaWilliams, GabrielaMoe, Paul RMoe, Paul R.Moe, Paul R.Wilbrandt, MichelleWilbrandt, MichelleWilbrandt, MichelleTisdale, James ETisdale, James E. and Tisdale, James E.
Pharmacotherapy, December 20, 2020. | Journal Article
 
Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation
Al Batran, RamiAl Batran, RamiGopal, KeshavGopal, KeshavCapozzi, Megan ECapozzi, Megan EChahade, Jadin JChahade, Jadin JSaleme, BrunoSaleme, BrunoTabatabaei-Dakhili, S AmirhosseinTabatabaei-Dakhili, S. AmirhosseinGreenwell, Amanda AGreenwell, Amanda ANiu, JingjingNiu, JingjingAlmutairi, MalakAlmutairi, MalakByrne, Nikole JByrne, Nikole JMasson, GrantMasson, GrantKim, RyekjangKim, RyekjangEaton, FarahEaton, FarahMulvihill, Erin EMulvihill, Erin EGarneau, LéaGarneau, LéaMasters, Andrea RMasters, Andrea RDesta, ZeruesenayDesta, ZeruesenayVelázquez-Martínez, Carlos AVelázquez-Martínez, Carlos AAguer, CélineAguer, CélineCrawford, Peter ACrawford, Peter ASutendra, GopinathSutendra, GopinathCampbell, Jonathan ECampbell, Jonathan EDyck, Jason R BDyck, Jason R.BUssher, John R and Ussher, John R
Cell Metabolism, vol. 31, (no. 5), pp. 919.e8, 2020-05-05. | Journal Article
 
Probenecid-Boosted Tenofovir: A Physiologically-Based Pharmacokinetic Model-Informed Strategy for On-Demand HIV Preexposure Prophylaxis.
Liu, Stephanie NDesta, Zeruesenay and Gufford, Brandon T
CPT: pharmacometrics & systems pharmacology, vol. 9, (no. 1), pp. 40-47, January 2020. | Journal Article
 
Probenecid‐Boosted Tenofovir: A Physiologically‐Based Pharmacokinetic Model‐Informed Strategy for On‐Demand HIV Preexposure Prophylaxis
Liu, Stephanie NLiu, Stephanie NDesta, ZeruesenayDesta, ZeruesenayGufford, Brandon T and Gufford, Brandon T
CPT: Pharmacometrics & Systems Pharmacology, vol. 9, (no. 1), pp. 47, January 2020. | Journal Article
2019
Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2.
Dudenkov, Tanda M.Dudenkov, Tanda MDudenkov, Tanda M.Liu, DuanLiu, DuanLiu, DuanCairns, JunmeiCairns, JunmeiCairns, JunmeiDevarajan, SandhyaDevarajan, SandhyaDevarajan, SandhyaZhuang, YongxianZhuang, YongxianZhuang, YongxianIngle, James NIngle, James N.Ingle, James N.Buzdar, Aman U.Buzdar, Aman U.Buzdar, Aman URobson, Mark ERobson, Mark E.Robson, Mark E.Kubo, MichiakiKubo, MichiakiKubo, MichiakiBatzler, AnthonyBatzler, AnthonyBatzler, AnthonyBarman, PoulamiBarman, PoulamiBarman, PoulamiJenkins, Gregory DJenkins, Gregory D.Jenkins, Gregory D.Carlson, Erin E.Carlson, Erin ECarlson, Erin E.Goetz, Matthew PGoetz, Matthew P.Goetz, Matthew P.Northfelt, Donald W.Northfelt, Donald W.Northfelt, Donald WMoreno‐Aspitia, AlvaroMoreno-Aspitia, AlvaroMoreno‐Aspitia, AlvaroDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayReid, Joel M.Reid, Joel MReid, Joel M.Kalari, Krishna RKalari, Krishna R.Kalari, Krishna R.Wang, LieweiWang, LieweiWang, LieweiWeinshilboum, Richard M.Weinshilboum, Richard M and Weinshilboum, Richard M.
Clinical pharmacology and therapeutics, vol. 106, (no. 1), pp. 219-227, July 2019. | Journal Article
 
Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome‐Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2
Dudenkov, Tanda MDudenkov, Tanda MLiu, DuanLiu, DuanCairns, JunmeiCairns, JunmeiDevarajan, SandhyaDevarajan, SandhyaZhuang, YongxianZhuang, YongxianIngle, James NIngle, James NBuzdar, Aman UBuzdar, Aman URobson, Mark ERobson, Mark EKubo, MichiakiKubo, MichiakiBatzler, AnthonyBatzler, AnthonyBarman, PoulamiBarman, PoulamiJenkins, Gregory DJenkins, Gregory DCarlson, Erin ECarlson, Erin EGoetz, Matthew PGoetz, Matthew PNorthfelt, Donald WNorthfelt, Donald WMoreno‐Aspitia, AlvaroMoreno‐Aspitia, AlvaroDesta, ZeruesenayDesta, ZeruesenayReid, Joel MReid, Joel MKalari, Krishna RKalari, Krishna RWang, LieweiWang, LieweiWeinshilboum, Richard M and Weinshilboum, Richard M
Clinical Pharmacology & Therapeutics, vol. 106, (no. 1), pp. 227, July 2019. | Journal Article
 
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2B6 and Efavirenz-Containing Antiretroviral Therapy.
Desta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayDesta, ZeruesenayGammal, Roseann S.Gammal, Roseann S.Gammal, Roseann S.Gammal, Roseann SGammal, Roseann S.Gammal, Roseann S.Gammal, Roseann S.Gammal, Roseann SGammal, Roseann S.Gammal, Roseann S.Gammal, Roseann S.Gammal, Roseann S.Gammal, Roseann S.Gammal, Roseann S.Gammal, Roseann S.Gammal, Roseann S.Gong, LiGong, LiGong, LiGong, LiGong, LiGong, LiGong, LiGong, LiGong, LiGong, LiGong, LiGong, LiGong, LiGong, LiGong, LiGong, LiWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleWhirl Carrillo, MichelleWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleWhirl-Carrillo, MichelleGaur, Aditya H.Gaur, Aditya H.Gaur, Aditya HGaur, Aditya HGaur, Aditya H.Gaur, Aditya H.Gaur, Aditya H.Gaur, Aditya H.Gaur, Aditya H.Gaur, Aditya H.Gaur, Aditya H.Gaur, Aditya H.Gaur, Aditya H.Gaur, Aditya H.Gaur, Aditya H.Gaur, Aditya H.Sukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatSukasem, ChonlaphatHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferHockings, JenniferMyers, AlanMyers, AlanMyers, AlanMyers, AlanMyers, AlanMyers, AlanMyers, AlanMyers, AlanMyers, AlanMyers, AlanMyers, AlanMyers, AlanMyers, AlanMyers, AlanMyers, AlanMyers, AlanSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeSwart, MarelizeTyndale, RachelTyndale, Rachel F.Tyndale, Rachel FTyndale, Rachel F.Tyndale, RachelTyndale, Rachel F.Tyndale, RachelTyndale, RachelTyndale, RachelTyndale, Rachel F.Tyndale, RachelTyndale, RachelTyndale, Rachel F.Tyndale, Rachel F.Tyndale, Rachel FTyndale, RachelMasimirembwa, Collenal.Masimirembwa, CollenIwuchukwu, Otito FIwuchukwu, Otito FChirwa, SanikaChirwa, SanikaLennox, JeffreyLennox, JeffreyGaedigk, AndreaGaedigk, AndreaKlein, Teri EKlein, Teri EHaas, David W and Haas, David W
Clinical pharmacology and therapeutics, vol. 106, (no. 4), pp. 726-733, October 2019. | Journal Article
 
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2B6 and Efavirenz‐Containing Antiretroviral Therapy
Desta, ZeruesenayDesta, ZeruesenayGammal, Roseann SGammal, Roseann SGong, LiGong, LiWhirl‐Carrillo, MichelleWhirl‐Carrillo, MichelleGaur, Aditya HGaur, Aditya HSukasem, ChonlaphatSukasem, ChonlaphatHockings, JenniferHockings, JenniferMyers, AlanMyers, AlanSwart, MarelizeSwart, MarelizeTyndale, Rachel FTyndale, Rachel FMasimirembwa, CollenMasimirembwa, CollenIwuchukwu, Otito FIwuchukwu, Otito FChirwa, SanikaChirwa, SanikaLennox, JeffreyLennox, JeffreyGaedigk, AndreaGaedigk, AndreaKlein, Teri EKlein, Teri EHaas, David W and Haas, David W
Clinical Pharmacology & Therapeutics, vol. 106, (no. 4), pp. 733, October 2019. | Journal Article
 
CYP2B6 Genotype-Dependent Inhibition of CYP1A2 and Induction of CYP2A6 by the Antiretroviral Drug Efavirenz in Healthy Volunteers.
Metzger, Ingrid FDave, NimitaKreutz, YvonneLu, Jessica B LGalinsky, Raymond E and Desta, Zeruesenay
Clinical and translational science, vol. 12, (no. 6), pp. 657-666, November 2019. | Journal Article
 
CYP2B6 Genotype‐Dependent Inhibition of CYP1A2 and Induction of CYP2A6 by the Antiretroviral Drug Efavirenz in Healthy Volunteers
Metzger, Ingrid FDave, NimitaKreutz, YvonneLu, Jessica B.LGalinsky, Raymond E and Desta, Zeruesenay
Clinical and Translational Science, vol. 12, (no. 6), pp. 666, November 2019. | Journal Article