32 Publications (Page 1 of 2)
2013
Epigenetic regulation of NANOG by miR-302 cluster-MBD2 completes induced pluripotent stem cell reprogramming.
Lee, Man R⋅Prasain, Nutan⋅Chae, Hee-Don⋅Kim, Young June⋅Mantel, Charlie R⋅Yoder, Mervin C and Broxmeyer, Hal E
Stem cells (Dayton, Ohio), vol. 31, (no. 4), pp. 666-81, 2013/Apr. | Journal Article
 
Spontaneously differentiated GATA6-positive human embryonic stem cells represent an important cellular step in human embryonic development; they are not just an artifact of in vitro culture.
Lee, Jun H⋅Hong, Ki S⋅Mantel, Charlie R⋅Broxmeyer, Hal E⋅Lee, Man R and Kim, Kye-Seong
Stem cells and development, vol. 22, (no. 20), pp. 2706-13, 2013/Oct/15. | Journal Article
2012
Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis
Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Hoggatt, Jonathan⋅Hoggatt, Jonathan⋅Hoggatt, Jonathan⋅O'leary, Heather A⋅O'leary, Heather A⋅O'Leary, Heather A⋅O’Leary, Heather A⋅Mantel, Charlie⋅Mantel, Charlie R⋅Mantel, Charlie⋅Chitteti, Brahmananda R⋅Chitteti, Brahmananda R⋅Chitteti, Brahmananda R⋅Cooper, Scott⋅Cooper, Scott⋅Cooper, Scott⋅Messina-Graham, Steven⋅Messina-graham, Steven⋅Messina-Graham, Steven⋅Messina-graham, Steven⋅Hangoc, Giao⋅Hangoc, Giao⋅Hangoc, Giao⋅Farag, Sherif S⋅Farag, Sherif⋅Farag, Sherif⋅Rohrabaugh, Sara L⋅Rohrabaugh, Sara L⋅Rohrabaugh, Sara L⋅Ou, Xuan⋅Ou, Xuan⋅Ou, Xuan⋅Speth, Jennifer⋅Speth, Jennifer⋅Speth, Jennifer⋅Pelus, Louis M⋅Pelus, Louis M⋅Pelus, Louis M⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Campbell, Timothy B⋅Campbell, Timothy B and Campbell, Timothy B
Nature Medicine, vol. 18, (no. 12), pp. 1786-96, Dec 2012. | Journal Article
 
Mouse hematopoietic cell-targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging-like phenotype.
Mantel, Charlie R⋅Messina-Graham, Steven⋅Moh, Akira⋅Cooper, Scott⋅Hangoc, Giao⋅Fu, Xin-Yuan and Broxmeyer, Hal E
Blood, vol. 120, (no. 13), pp. 2589-99, 2012/Sep/27. | Journal Article
2011
Superoxide flashes, reactive oxygen species, and the mitochondrial permeability transition pore: potential implications for hematopoietic stem cell function.
Mantel, Charlie⋅Mantel, Charlie R⋅Messina-Graham, Steven V⋅Messina-Graham, Steven⋅Broxmeyer, Hal E and Broxmeyer, Hal
Current opinion in hematology, vol. 18, (no. 4), pp. 208-13, 2011/Jul. | Journal Article
 
TIP110/p110nrb/SART3/p110 regulation of hematopoiesis through CMYC.
Liu, Ying⋅Timani, Khalid⋅Mantel, Charlie R⋅Fan, Yan⋅Hangoc, Giao⋅Cooper, Scott⋅He, Johnny J and Broxmeyer, Hal E
Blood, vol. 117, (no. 21), pp. 5643-51, 2011/May/26. | Journal Article
2010
Upregulation of nascent mitochondrial biogenesis in mouse hematopoietic stem cells parallels upregulation of CD34 and loss of pluripotency: a potential strategy for reducing oxidative risk in stem cells.
Mantel, Charlie R⋅Messina-Graham, Steve and Broxmeyer, Hal E
Cell cycle (Georgetown, Tex.), vol. 9, (no. 10), pp. 2008-17, 2010/May/15. | Journal Article
2008
Cells enter a unique intermediate 4N stage, not 4N-G1, after aborted mitosis.
Mantel, Charlie R⋅Guo, Ying⋅Lee, Man R⋅Han, Myung K⋅Rhorabough, Sara⋅Kim, Kye S and Broxmeyer, Hal E
Cell cycle (Georgetown, Tex.), vol. 7, (no. 4), pp. 484-92, 2008/Feb/15. | Journal Article
 
Mouse hematopoietic stem cells, unlike human and mouse embryonic stem cells, exhibit checkpoint-apoptosis coupling.
Rohrabaugh, Sara⋅Mantel, Charlie R and Broxmeyer, Hal E
Stem cells and development, vol. 17, (no. 5), pp. 1017-20, 2008/Oct. | Journal Article
 
Oct-4 Is Critical for Survival/Antiapoptosis of Murine Embryonic Stem Cells Subjected to Stress: Effects Associated with Stat3/Survivin
Guo, Ying⋅Mantel, Charlie R⋅Hromas, Robert A and Broxmeyer, Hal E
Stem Cells, vol. 26, (no. 1), pp. 30-34, 2008. | Journal Article
 
Sirt1, notch and stem cell "age asymmetry".
Mantel, Charlie R⋅Wang, Rui-Hong⋅Deng, Chuxia and Broxmeyer, Hal E
Cell cycle (Georgetown, Tex.), vol. 7, (no. 18), pp. 2821-5, 2008/Sep/15. | Journal Article
 
SIRT1 Regulates Apoptosis and Nanog Expression in Mouse Embryonic Stem Cells by Controlling p53 Subcellular Localization
Han, Myung-Kwan⋅Song, Eun-Kyung⋅Guo, Ying⋅Ou, Xuan⋅Mantel, Charlie R and Broxmeyer, Hal E
Cell Stem Cell, vol. 2, (no. 3), pp. 241-251, 2008. | Journal Article
2007
Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instability.
Mantel, Charlie R⋅Guo, Ying⋅Lee, Man R⋅Kim, Min-Kyoung⋅Han, Myung-Kwan⋅Shibayama, Hirohiko⋅Fukuda, Seiji⋅Yoder, Mervin C⋅Pelus, Louis M⋅Kim, Kye-Seong and Broxmeyer, Hal E
Blood, vol. 109, (no. 10), pp. 4518-27, 2007/May/15. | Journal Article
 
Mad2 is required for optimal hematopoiesis: Mad2 associates with c-Kit in MO7e cells.
Ito, Shigeki⋅Mantel, Charlie R⋅Han, Myung-Kwan⋅Basu, Sunanda⋅Fukuda, Seiji⋅Cooper, Scott and Broxmeyer, Hal E
Blood, vol. 109, (no. 5), pp. 1923-30, 2007/Mar/1. | Journal Article
2004
Modulation of Hematopoietic Stem Cell Homing and Engraftment by CD26
Christopherson, Kent W⋅Hangoc, Giao⋅Mantel, Charlie R and Broxmeyer, Hal E
Science, vol. 305, (no. 5686), pp. 1000-3, Aug 13, 2004. | Journal Article
 
Survivin regulates hematopoietic progenitor cell proliferation through p21WAF1/Cip1-dependent and -independent pathways.
Fukuda, Seiji⋅Mantel, Charlie R and Pelus, Louis M
Blood, vol. 103, (no. 1), pp. 120-7, 2004/Jan/1. | Journal Article
2003
Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and G alpha i proteins and enhances engraftment of competitive, repopulating stem cells
Broxmeyer, Hal E⋅Kohli, L.⋅Kim, Chang H⋅Lee, Younghee⋅Mantel, Charlie R⋅Cooper, S.⋅Hangoc, G.⋅Shaheen, M.⋅Li, Xiaxin and Wade Clapp, D.
Journal of Leukocyte Biology, vol. 73, (no. 5), pp. 630-638, 2003. | Journal Article
 
Transgenic Expression of Stromal Cell-Derived Factor-1/CXC Chemokine Ligand 12 Enhances Myeloid Progenitor Cell Survival/Antiapoptosis In Vitro in Response to Growth Factor Withdrawal and Enhances Myelopoiesis In Vivo
Broxmeyer, Hal E⋅Broxmeyer, Hal⋅Cooper, S.⋅Cooper, Scott⋅Kohli, L.⋅Kohli, Lisa⋅Hangoc, G.⋅Hangoc, Giao⋅Lee, Younghee⋅Lee, Y.⋅Mantel, Charlie⋅Mantel, Charlie R⋅Clapp, David W⋅Clapp, D.⋅Kim, Chang and Kim, Chang H
Journal of Immunology, vol. 170, (no. 1), pp. 421-429, 2003. | Journal Article
2002
C-kit associated with the transmembrane 4 superfamily proteins constitutes a functionally distinct subunit in human hematopoietic progenitors.
Anzai, Naoyuki⋅Lee, Younghee⋅Youn, Byung-S⋅Fukuda, Seiji⋅Kim, Young June⋅Mantel, Charlie R⋅Akashi, Makoto and Broxmeyer, Hal E
Blood, vol. 99, (no. 12), pp. 4413-21, 2002/Jun/15. | Journal Article
 
Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines.
Lee, Younghee⋅Gotoh, Akihiko⋅Kwon, Hyung-Joo⋅You, Minute⋅Kohli, Lisa⋅Mantel, Charlie R⋅Cooper, Scott⋅Hangoc, Giao⋅Miyazawa, Keisuke⋅Ohyashiki, Kazuma and Broxmeyer, Hal E
Blood, vol. 99, (no. 12), pp. 4307-17, 2002/Jun/15. | Journal Article
 
P21waf-1-Chk1 pathway monitors G1 phase microtubule integrity and is crucial for restriction point transition.
Mantel, Charlie R⋅Gelfano, Vasily M⋅Kim, Young-June⋅McDaniel, Andrew⋅Lee, Younghee⋅Boswell, H S and Broxmeyer, Hal E
Cell cycle (Georgetown, Tex.) , vol. 1, (no. 5), pp. 327-36, 2002 Sep-Oct. | Journal Article
2001
Steel factor regulates cell cycle asymmetry.
Mantel, Charlie R⋅Mantel, Charlie⋅Hendrie, P⋅Hendrie, Paul⋅Broxmeyer, H E and Broxmeyer, Hal E
Stem cells (Dayton, Ohio) , vol. 19, (no. 6), pp. 483-91, 2001. | Journal Article
 
The interphase microtubule damage checkpoint defines an S-phase commitment point and does not require p21(waf-1).
Mantel, Charlie R⋅Braun, S E⋅Lee, Y⋅Kim, Y J and Broxmeyer, H E
Blood. , vol. 97, (no. 5), pp. 1505-7, 2001/Mar/1. | Journal Article
 
Transcriptional and ERK1/2-Dependent Synergistic Upregulation of p21 Associated with Steel Factor Synergy in MO7e
Lee, Y.⋅Mantel, Charlie R⋅Anzai, N.⋅Braun, SE and Broxmeyer, Hal E
Biochemical and Biophysical Research Communications, vol. 280, (no. 3), pp. 675-683, 2001. | Journal Article
2000
Chemokines, chemokine receptors and hematopoiesis
Youn, B-S⋅Mantel, Charlie R and Broxmeyer, Hal E
Immunological Reviews, vol. 177, pp. 150-174, 2000. | Journal Article