94 Publications (Page 3 of 4)
1999
Photoaffinity analogs for multidrug resistance-related transporters and their use in identifying chemosensitizersSafa, Ahmad RDrug Resistance Updates, vol. 2, (no. 6), pp. 381, December 1999.
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Synergistic effect of gemcitabine and irinotecan (CPT-11) on breast and small cell lung cancer cell lines.Bahadori, H R⋅Rocha Lima, C M⋅Green, M R and Safa, Ahmad RAnticancer Research, vol. 19, (no. 6B), pp. 5423-8, 1999 Nov-Dec.
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1998
[21] Photoaffinity labels for characterizing drug interaction sites of P-glycoproteinSafa, Ahmad RMethods in Enzymology, vol. 292, pp. 307, 1998.
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Cell-Specific Modulation of Drug Resistance in Acute Myeloid Leukemic Blasts by Diphtheria Fusion Toxin, DT388-GMCSFFrankel, Arthur E⋅Frankel, Arthur E⋅Hall, Philip D⋅Hall, Philip D⋅McLain, C⋅McLain, Chris⋅Safa, Ahmad R⋅Safa, A R⋅Tagge, Edward P⋅Tagge, Edward P⋅Kreitman, Robert J and Kreitman, R JBioconjugate Chemistry, vol. 9, (no. 4), pp. 496, 19980713.
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Co‐ordinated over‐expression of the MRP and γ‐glutamylcysteine synthetase genes, but not MRD1, correlates with doxorubicin resistance in human malignant mesothelioma cell linesOgretmen, Besim⋅Bahadori, Hamid R⋅McCauley, Mary D⋅Boylan, Alice⋅Green, Mark R and Safa, Ahmad RInternational Journal of Cancer, vol. 75, (no. 5), pp. 761, 1998-03-02.
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Effects of 1,2-naphthoquinones on human tumor cell growth and lack of cross-resistance with other anticancer agentsDolan, M. E⋅Dolan, M Eileen⋅Frydman, B.⋅Frydman, Benjamin⋅Thompson, CB⋅Thompson, Craig⋅Diamond, AM⋅Diamond, Alan⋅Garbiras, BJ⋅Garbiras, Bonnie⋅Safa, AR⋅Safa, Ahmad⋅Beck, William⋅Beck, WT⋅Marton, Laurence J and Marton, LaurenceAnti-Cancer Drugs, vol. 9, (no. 5), pp. 448, 1998-June.
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Lack of correlation of MRP and γ-glutamylcysteine synthetase overexpression with doxorubicin resistance due to increased apoptosis in SV40 large T-antigen-transformed human mesothelial cellsOgretmen, Besim⋅Bahadori, Hamid⋅McCauley, Mary⋅Boylan, Alice⋅Green, Mark and Safa, Ahmad RCancer Chemotherapy and Pharmacology, vol. 42, (no. 6), pp. 446, 19981000.
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Molecular mechanisms of loss of beta2-microglobulin expression in drug-resistant breast cancer sublines and its involvement in drug resistanceOgretmen, Besim⋅McCauley, Mary and Safa, AhmadBiochemistry, vol. 37, (no. 33), pp. 11679, 19980818.
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Molecular Mechanisms of Loss of β2-Microglobulin Expression in Drug-Resistant Breast Cancer Sublines and Its Involvement in Drug ResistanceOgretmen, Besim⋅McCauley, Mary D and Safa, Ahmad RBiochemistry, vol. 37, (no. 33), pp. 11691, 19980818.
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1997
Expression of the mutated p53 tumor suppressor protein and its molecular and biochemical characterization in multidrug resistant MCF-7/Adr human breast cancer cellsOgretmen, Besim⋅Safa, AR and Safa, Ahmad ROncogene, vol. 14, (no. 4), pp. 499-506, Jan 1997.
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1996
Down‐regulation of apoptosis‐related bcl‐2 but not bcl‐xL or bax proteins in multidrug‐resistant MCF‐7/Adr human breast cancer cellsOgretmen, Besim and Safa, Ahmad RInternational Journal of Cancer, vol. 67, (no. 5), pp. 614, 4 September 1996.
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Pharmacokinetic Modulation of Irinotecan and Metabolites by Cyclosporin AGupta, E⋅Gupta, Elora⋅Safa, Ahmad⋅Safa, A R⋅Wang, X⋅Wang, Xiaolin⋅Ratain, Mark J and Ratain, MarkCancer Research, vol. 56, (no. 6), pp. 1309, 19960315.
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Reversal of multi‐drug resistance in vitro by fatty acid PEG fatty acid diestersBuckingham, Lela E⋅Balasubramanian, M⋅Safa, Ahmad R⋅Shah, Himanshu⋅Komarov, Pavel⋅Emanuele, R. Martin and Coon, John SInternational Journal of Cancer, vol. 65, (no. 1), pp. 79, 3 January 1996.
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Site-Directed Mutagenesis by Unique Site Elimination Using Filamentous Phage-Derived ssDNA Templates for Plasmids That Are Resistant to DenaturationOgretmen, Besim⋅Ogretmen, Besim⋅Carpo, C⋅Carpo, Cynthia⋅Safa, A R and Safa, Ahmad RBioTechniques, vol. 21, (no. 2), pp. 213, 1996-August-01.
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1995
Partial Inhibition of Multidrug Resistance by Safingol Is Independent of Modulation of P-glycoprotein Substrate Activities and Correlated with Inhibition of Protein Kinase CSachs, Clifford⋅Safa, Ahmad⋅Harrison, Steadman and Fine, RobertJournal of Biological Chemistry, vol. 270, (no. 44), pp. 26648, 19951103.
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1994
Modulation of P-Glycoprotein by Protein Kinase C.alpha. in a Baculovirus Expression SystemAhmad, Shakeel⋅Safa, Ahmad R and Glazer, Robert IBiochemistry, vol. 33, (no. 34), pp. 10318, 19940801.
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N-(p-azido-3-[125I]iodophenethyl)spiperone binds to specific regions of P-glycoprotein and another multidrug binding protein, spiperophilin, in human neuroblastoma cellsSafa, Ahmad R⋅Agresti, Michael⋅Bryk, David and Tamai, IkumiBiochemistry, vol. 33, (no. 1), pp. 265, 19940101.
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Relationship of P‐glycoprotein and carcinoembryonic antigen expression in human colon carcinoma to local invasion, dna ploidy, and disease relapseSinicrope, Frank A⋅Sinicrope, Frank A⋅Hart, J⋅Hart, John⋅Brasitus, Thomas A⋅Brasitus, Thomas A⋅Michelassi, F⋅Michelassi, Fabrizio⋅Lee, J J⋅Lee, J. Jack⋅Safa, A R and Safa, Ahmad RCancer, vol. 74, (no. 11), pp. 2917, 1 December 1994.
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1993
Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding siteKajiji, Shama⋅Talbot, France⋅Grizzuti, Kart⋅Van Dyke-Phillips, Valerie⋅Agresti, Michael⋅Safa, Ahmad R and Gros, PhilippeBiochemistry, vol. 32, (no. 16), pp. 4194, 19930401.
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Modulation of vinblastine resistance with cyclosporine: A phase I studySamuels, B L⋅Samuels, Brian L⋅Mick, Rosemarie⋅Mick, R⋅Vogelzang, Nicholas J⋅Vogelzang, Nicholas J⋅Williams, Stephanie F⋅Williams, S F⋅Schilsky, Richard L⋅Schilsky, Richard L⋅Safa, Ahmad R⋅Safa, A R⋅O'Brien, S M⋅O'brien, Sheila M⋅Ratain, Mark J and Ratain, Mark JClinical Pharmacology and Therapeutics, vol. 54, (no. 4), pp. 429, 1993-10-00.
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Photoaffinity Labeling of P-Glycoprotein in Multidrug-Resistant CellsSafa, Ahmad RCancer Investigation, vol. 11, (no. 1), pp. 56, 19930000.
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1992
Photoaffinity Labeling of P-Glycoprotein in Multidrug-Resistant CellsSafa, Ahmad RCancer Investigation, vol. 10, (no. 4), pp. 305, 19920000.
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1991
Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug resistant cells.Tamai, I and Safa, A RThe Journal of biological chemistry, vol. 266, (no. 25), pp. 16796-16800, September 5, 1991.
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Increased Glutathione Peroxidase Activity in a Human Sarcoma Cell Line with Inherent Doxorubicin ResistanceSamuels, B L⋅Samuels, Brian⋅Murray, J L⋅Murray, Judith⋅Cohen, M B⋅Cohen, Marvin⋅Safa, A R⋅Safa, Ahmad⋅Sinha, B K⋅Sinha, Birandra⋅Townsend, Alan⋅Townsend, A J⋅Beckett, M A⋅Beckett, Michael⋅Weichselbaum, Ralph and Weichselbaum, Ralph RCancer Research, vol. 51, (no. 2), pp. 521, 19910115.
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1990
Molecular Basis of Preferential Resistance to Colchicine in Multidrug- Resistant Human Cells Conferred by Gly-185 → Val-185 Substitution in P-GlycoproteinSafa, Ahmad⋅Stern, Randi⋅Choi, Kyunghee⋅Agresti, Michael⋅Tamai, Ikumi⋅Mehta, Nitin and Roninson, IgorProceedings of the National Academy of Sciences of the United States of America, vol. 87, (no. 18), pp. 7229, 19900901.
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