94 Publications (Page 1 of 4)
2019
c-FLIP, a Novel Biomarker for Cancer Prognosis, Immunosuppression, Alzheimer's Disease, Chronic Obstructive Pulmonary Disease (COPD), and a Rationale Therapeutic Target
Safa, Ahmad RSafa, Ahmad RKamocki, KrzysztofKamocki, KrzysztofSaadatzadeh, M RezaSaadatzadeh, M RezaBijangi Vishehsaraei, Khadijeh and Bijangi-Vishehsaraei, Khadijeh
Biomarkers journal, vol. 5, (no. 1), 2019-00-00. | Journal Article
2018
Abstract 4862: Protein arginine methyltransferase 5 as a tumor promoter and therapeutic target in gastrointestinal cancers
Prabhu, LakshmiChen, LanSafa, AhmadKorc, MurrayZhang, Zhong-Yin and Lu, Tao
Cancer Research, vol. 78, (no. 13 Supplement), pp. 4862, 2018-07-01. | Journal Article
 
A Dose-escalation Study of Recombinant Human Interleukin-18 in Combination With Ofatumumab After Autologous Peripheral Blood Stem Cell Transplantation for Lymphoma
Robertson, Michael JRobertson, Michael JStamatkin, Christopher WStamatkin, Christopher WPelloso, DavidPelloso, DavidWeisenbach, JillWeisenbach, JillPrasad, Nagendra KPrasad, Nagendra KSafa, Ahmad R and Safa, Ahmad R
Journal of immunotherapy (Hagerstown, Md. : 1997), vol. 41, (no. 3), pp. 157, 2018-Apr. | Journal Article
2017
Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.
Prabhu, LakshmiPrabhu, LakshmiWei, HanWei, HanChen, LanChen, LanDemir, ÖzlemDemir, ÖzlemSandusky, GeorgeSandusky, GeorgeSun, EmilySun, EmilyWang, JohnWang, JohnMo, JessicaMo, JessicaZeng, LifanZeng, LifanFishel, MelissaFishel, MelissaSafa, AhmadSafa, AhmadAmaro, RommieAmaro, RommieKorc, MurrayKorc, MurrayZhang, Zhong YinZhang, Zhong-YinLu, Tao and Lu, Tao
Oncotarget, vol. 8, (no. 25), pp. 39963-39977, June 20, 2017. | Journal Article
 
Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases
Prabhu, LakshmiPrabhu, LakshmiChen, LanChen, LanWei, HanWei, HanDemir, ÖzlemDemir, ÖzlemSafa, AhmadSafa, AhmadZeng, LifanZeng, LifanAmaro, Rommie EAmaro, Rommie EO'Neil, Bert HO'Neil, Bert HZhang, Zhon-YinZhang, Zhon-YinLu, Tao and Lu, Tao
Molecular bioSystems, vol. 13, (no. 12), pp. 2520, 2017-Nov-21. | Journal Article
 
Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell-like spheroids, and tumor xenografts through multiple cell signaling pathways.
Bijangi-Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehBijangi Vishehsaraei, KhadijehReza Saadatzadeh, MReza Saadatzadeh, MReza Saadatzadeh, MReza Saadatzadeh, MReza Saadatzadeh, MWang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanNguyen, AngieNguyen, AngieNguyen, AngieNguyen, AngieNguyen, AngieKamocka, Malgorzata MKamocka, Malgorzata MKamocka, Malgorzata MKamocka, Malgorzata MKamocka, Malgorzata MCai, WenjingCai, WenjingCai, WenjingCai, WenjingCai, WenjingCohen-Gadol, Aaron ACohen-Gadol, Aaron ACohen-Gadol, Aaron ACohen Gadol, Aaron ACohen-Gadol, Aaron AHalum, Stacey LHalum, Stacey LHalum, Stacey LHalum, Stacey LHalum, Stacey LSarkaria, Jann NSarkaria, Jann NSarkaria, Jann NSarkaria, Jann NSarkaria, Jann NPollok, Karen EPollok, Karen EPollok, Karen EPollok, Karen EPollok, Karen ESafa, Ahmad RSafa, Ahmad RSafa, Ahmad RSafa, Ahmad R and Safa, Ahmad R
Journal of neurosurgery, pp. 1-12, January 6, 2017. | Journal Article
2016
Microarray Analysis Gene Expression Profiles in Laryngeal Muscle After Recurrent Laryngeal Nerve Injury
Bijangi-Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehBlum, KevinBlum, KevinZhang, HongjiZhang, HongjiSafa, Ahmad RSafa, Ahmad RHalum, Stacey L and Halum, Stacey L
Annals of Otology, Rhinology & Laryngology, vol. 125, (no. 3), pp. 256, 20160300. | Journal Article
 
Resistance to Cell Death and Its Modulation in Cancer Stem Cells.
Safa, Ahmad R
Critical reviews in oncogenesis, vol. 21, (no. 3-4), pp. 203-219, 2016. | Journal Article
2015
Abstract B18: Targeting histone deacetylase 6 (HDAC6) depresses proliferation and induces caspase-associated cell death in glioblastoma multiforme (GBM) cells and GBM stem cell-like spheroids
Saadatzadeh, Mohammad RezaSaadatzadeh, Mohammad RezaSaadatzadeh, Mohammad RezaSaadatzadeh, Mohammad RezaVishehsaraei, Khadijeh BijangiVishehsaraei, Khadijeh BijangiVishehsaraei, Khadijeh BijangiVishehsaraei, Khadijeh BijangiWang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanCohen Gadol, AaronCohen-Gadol, AaronCohen-Gadol, AaronCohen-Gadol, AaronPollok, Karen EPollok, Karen EPollok, Karen EPollok, Karen ESafa, Ahmad RSafa, Ahmad RSafa, Ahmad R and Safa, Ahmad R
Cancer Research, vol. 75, (no. 23 Supplement), pp. B18, 2015-12-01. | Journal Article
 
Emerging targets for glioblastoma stem cell therapy.
Safa, Ahmad RSaadatzadeh, Mohammad RezaCohen-Gadol, Aaron APollok, Karen E and Bijangi-Vishehsaraei, Khadijeh
Journal of biomedical research, vol. 30, September 20, 2015. | Journal Article
 
Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs.
Safa, Ahmad RSafa, Ahmad RSafa, Ahmad RSafa, Ahmad RSaadatzadeh, Mohammad RezaSaadatzadeh, Mohammad RezaSaadatzadeh, Mohammad RezaSaadatzadeh, Mohammad RezaCohen-Gadol, Aaron ACohen-Gadol, Aaron ACohen-Gadol, Aaron ACohen Gadol, Aaron APollok, Karen EPollok, Karen EPollok, Karen EPollok, Karen EBijangi-Vishehsaraei, KhadijehBijangi Vishehsaraei, KhadijehBijangi-Vishehsaraei, Khadijeh and Bijangi-Vishehsaraei, Khadijeh
Genes & Diseases, vol. 2, (no. 2), pp. 152-163, June 2015. | Journal Article
 
Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model
Tonsing-Carter, EvaTonsing-Carter, EvaTonsing-Carter, E.Tonsing-Carter, EvaTonsing-Carter, EvaTonsing-Carter, EvaTonsing-Carter, EvaTonsing-Carter, EvaBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, B.J.Saadatzadeh, M RezaSaadatzadeh, M RezaSaadatzadeh, M RezaSaadatzadeh, M RezaSaadatzadeh, M RezaSaadatzadeh, M RezaSaadatzadeh, M RezaSaadatzadeh, M.R.Ding, JixinDing, J.Ding, JixinDing, JixinDing, JixinDing, JixinDing, JixinDing, JixinWang, HaiyanWang, HaiyanWang, H.Wang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanSinn, Anthony LSinn, Anthony LSinn, A.L.Sinn, Anthony LSinn, Anthony LSinn, Anthony LSinn, Anthony LSinn, Anthony LPeterman, Kacie MPeterman, Kacie MPeterman, Kacie MPeterman, Kacie MPeterman, Kacie MPeterman, Kacie MPeterman, K.M.Peterman, Kacie MSpragins, T.K.Spragins, Tiaishia KSpragins, Tiaishia KSpragins, Tiaishia KSpragins, Tiaishia KSpragins, Tiaishia KSpragins, Tiaishia KSpragins, Tiaishia KSilver, J.M.Silver, Jayne MSilver, Jayne MSilver, Jayne MSilver, Jayne MSilver, Jayne MSilver, Jayne MSilver, Jayne MSprouse, Alyssa ASprouse, Alyssa ASprouse, Alyssa ASprouse, Alyssa ASprouse, Alyssa ASprouse, Alyssa ASprouse, A.A.Sprouse, Alyssa AGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, T.M.Gunter, T ZacharyGunter, T.Z.Gunter, T ZacharyGunter, T ZacharyGunter, T ZacharyGunter, T ZacharyGunter, T ZacharyGunter, T ZacharyLong, Eric CLong, Eric CLong, Eric CLong, Eric CLong, Eric CLong, Eric CLong, E.C.Long, Eric CMinto, R.E.Minto, Robert EMinto, Robert EMinto, Robert EMinto, Robert EMinto, Robert EMinto, Robert EMinto, Robert EMarchal, Christophe CMarchal, Christophe CMarchal, Christophe CMarchal, Christophe CMarchal, Christophe CMarchal, Christophe CMarchal, C.C.Marchal, Christophe CBatuello, Christopher NBatuello, Christopher NBatuello, Christopher NBatuello, Christopher NBatuello, Christopher NBatuello, Christopher NBatuello, Christopher NBatuello, C.N.Safa, Ahmad RSafa, Ahmad RSafa, Ahmad RSafa, Ahmad RSafa, A.R.Safa, Ahmad RSafa, Ahmad RSafa, Ahmad RHanenberg, HelmutHanenberg, HelmutHanenberg, H.Hanenberg, HelmutHanenberg, HelmutHanenberg, HelmutHanenberg, HelmutHanenberg, HelmutTerrito, Paul RTerrito, Paul RTerrito, Paul RTerrito, Paul RTerrito, Paul RTerrito, Paul RTerrito, P.R.Territo, Paul RSandusky, George ESandusky, George ESandusky, George ESandusky, George ESandusky, G.E.Sandusky, George ESandusky, George ESandusky, George EMayo, L.D.Mayo, Lindsey DMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DEischen, Christine MEischen, Christine MEischen, Christine MEischen, C.M.Eischen, Christine MEischen, Christine MEischen, Christine MEischen, Christine MShannon, Harlan EShannon, Harlan EShannon, Harlan EShannon, Harlan EShannon, H.E.Shannon, Harlan EShannon, Harlan EShannon, Harlan EPollok, Karen EPollok, Karen EPollok, Karen EPollok, Karen EPollok, K.E.Pollok, Karen EPollok, Karen E and Pollok, Karen E
Molecular cancer therapeutics, vol. 14, (no. 12), pp. 2863, 2015-Dec. | Journal Article
2014
Abstract 2267: Sulforaphane depresses proliferation and induces cell death in glioblastoma multiforme (GBM) cells, GBM stem cell-like spheroids, and tumor xenografts through modulation of multiple cell signaling pathways
Bijangi-Vishehsaraei, KhadijehBijangi Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehSaadatzadeh, Mohammad RSaadatzadeh, Mohammad RSaadatzadeh, Mohammad RSaadatzadeh, Mohammad RSaadatzadeh, Mohammad RSaadatzadeh, Mohammad RWang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanKamocka, Malgorzata MKamocka, Malgorzata MKamocka, Malgorzata MKamocka, Malgorzata MKamocka, Malgorzata MKamocka, Malgorzata MCai, WenjingCai, WenjingCai, WenjingCai, WenjingCai, WenjingCai, WenjingCohen-Gadol, Aaron ACohen-Gadol, Aaron ACohen-Gadol, Aaron ACohen Gadol, Aaron ACohen-Gadol, Aaron ACohen-Gadol, Aaron AHalum, Stacey LHalum, Stacey LHalum, Stacey LHalum, Stacey LHalum, Stacey LHalum, Stacey LPollok, Karen EPollok, Karen EPollok, Karen EPollok, Karen EPollok, Karen EPollok, Karen ESarkaria, Jann NSarkaria, Jann NSarkaria, Jann NSarkaria, Jann NSarkaria, Jann NSarkaria, Jann NSafa, Ahmad RSafa, Ahmad RSafa, Ahmad RSafa, Ahmad RSafa, Ahmad R and Safa, Ahmad R
Cancer Research, vol. 74, (no. 19 Supplement), pp. 2267, 2014-10-01. | Journal Article
2013
Roles of c-FLIP in Apoptosis, Necroptosis, and Autophagy.
Safa, Ahmad R
Journal of carcinogenesis & mutagenesis, vol. Suppl6, 2013. | Journal Article
2012
c-FLIP, a master anti-apoptotic regulator.
Safa, Ahmad R
Experimental oncology, vol. 34, (no. 3), pp. 176-84, 2012/Oct. | Journal Article
 
Human GM3 Synthase Attenuates Taxol-Triggered Apoptosis Associated with Downregulation of Caspase-3 in Ovarian Cancer Cells.
Huang, SuHuang, SuBijangi-Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehSaadatzadeh, Mohammad RezaSaadatzadeh, Mohammad RezaSafa, Ahmad R and Safa, Ahmad R
Journal of cancer therapy, vol. 3, (no. 5), pp. 504-510, October 2012. | Journal Article
2011
Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy
Safa, Ahmad and Pollok, Karen
(pp. 1639-1671). 2011
2010
4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide (CMH) targets mRNA of the c-FLIP variants and induces apoptosis in MCF-7 human breast cancer cells
Bijangi-Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehBijangi Vishehsaraei, KhadijehSaadatzadeh, MohammadSaadatzadeh, Mohammad RSaadatzadeh, MohammadHuang, SuHuang, SuHuang, SuMurphy, Michael PMurphy, MichaelMurphy, MichaelSafa, AhmadSafa, Ahmad R and Safa, Ahmad
Molecular and Cellular Biochemistry, vol. 342, (no. 1-2), pp. 133-142, 2010. | Journal Article
 
Selective TRAIL-triggered apoptosis due to overexpression of TRAIL death receptor 5 (DR5) in P-glycoprotein-bearing multidrug resistant CEM/VBL1000 human leukemia cells.
Park, Soo-JungPark, Soo-JungBijangi-Vishehsaraei, KhadijehBijangi Vishehsaraei, KhadijehSafa, Ahmad R and Safa, Ahmad R
International journal of biochemistry and molecular biology, vol. 1, (no. 1), pp. 90-100, 2010. | Journal Article
2009
c-FLIP gene silencing eliminates tumor cells in breast cancer xenografts without affecting stromal cells.
Day, Travis WDAY, TRAVISSinn, Anthony LSINN, ANTHONYHuang, SuHUANG, SUPollok, Karen EPOLLOK, KARENSandusky, George ESandusky, GeorgeSafa, Ahmad R and SAFA, AHMAD
Anticancer research, vol. 29, (no. 10), pp. 3883-6, 2009/Oct. | Journal Article
 
Dynamic assessment of mitoxantrone resistance and modulation of multidrug resistance by valspodar (PSC833) in multidrug resistance human cancer cells.
Shen, FeiBailey, Barbara JChu, ShaoyouBence, Aimee KXue, XinjianErickson, PriscillaSafa, Ahmad RBeck, William T and Erickson, Leonard C
The Journal of pharmacology and experimental therapeutics, vol. 330, (no. 2), pp. 423-9, 2009/Aug. | Journal Article
 
Etoposide induces protein kinase Cdelta- and caspase-3-dependent apoptosis in neuroblastoma cancer cells.
Day, Travis WWu, Ching-Huang and Safa, Ahmad R
Molecular pharmacology, vol. 76, (no. 3), pp. 632-40, 2009/Sep. | Journal Article
 
Human beta-galactoside alpha-2,3-sialyltransferase (ST3Gal III) attenuated Taxol-induced apoptosis in ovarian cancer cells by downregulating caspase-8 activity.
Huang, SuDay, Travis WChoi, Mi Ran and Safa, Ahmad R
Molecular and cellular biochemistry, vol. 331, (no. 1-2), pp. 81-8, 2009/Nov. | Journal Article
 
Human β-galactoside α-2,3-sialyltransferase (ST3Gal III) attenuated Taxol-induced apoptosis in ovarian cancer cells by downregulating caspase-8 activity
Huang, SuDay, Travis WChoi, Mi Ran and Safa, Ahmad R
Molecular and cellular biochemistry., vol. 331, (no. 1-2), pp. 81-88, 2009. | Journal Article
 
RNA Interference in Cancer: Targeting the Anti-Apoptotic Protein c-FLIP for Drug Discovery
Day, Travis W and Safa, Ahmad R
Mini-Reviews in Medicinal Chemistry, vol. 9, (no. 6), pp. 741-748, 2009. | Journal Article