94 Publications (Page 1 of 4)
2019
c-FLIP, a Novel Biomarker for Cancer Prognosis, Immunosuppression, Alzheimer's Disease, Chronic Obstructive Pulmonary Disease (COPD), and a Rationale Therapeutic Target
Safa, Ahmad R⋅Safa, Ahmad R⋅Kamocki, Krzysztof⋅Kamocki, Krzysztof⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Bijangi-Vishehsaraei, Khadijeh and Bijangi Vishehsaraei, Khadijeh
Biomarkers journal, vol. 5, (no. 1), 2019-00-00. | Journal Article
2018
Abstract 4862: Protein arginine methyltransferase 5 as a tumor promoter and therapeutic target in gastrointestinal cancers
Prabhu, Lakshmi⋅Chen, Lan⋅Safa, Ahmad⋅Korc, Murray⋅Zhang, Zhong-Yin and Lu, Tao
Cancer Research, vol. 78, (no. 13 Supplement), pp. 4862, 2018-07-01. | Journal Article
 
A Dose-escalation Study of Recombinant Human Interleukin-18 in Combination With Ofatumumab After Autologous Peripheral Blood Stem Cell Transplantation for Lymphoma
Robertson, Michael J⋅Robertson, Michael J⋅Stamatkin, Christopher W⋅Stamatkin, Christopher W⋅Pelloso, David⋅Pelloso, David⋅Weisenbach, Jill⋅Weisenbach, Jill⋅Prasad, Nagendra K⋅Prasad, Nagendra K⋅Safa, Ahmad R and Safa, Ahmad R
Journal of immunotherapy (Hagerstown, Md. : 1997), vol. 41, (no. 3), pp. 157, 2018-Apr. | Journal Article
2017
Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.
Prabhu, Lakshmi⋅Prabhu, Lakshmi⋅Wei, Han⋅Wei, Han⋅Chen, Lan⋅Chen, Lan⋅Demir, Özlem⋅Demir, Özlem⋅Sandusky, George⋅Sandusky, George⋅Sun, Emily⋅Sun, Emily⋅Wang, John⋅Wang, John⋅Mo, Jessica⋅Mo, Jessica⋅Zeng, Lifan⋅Zeng, Lifan⋅Fishel, Melissa⋅Fishel, Melissa⋅Safa, Ahmad⋅Safa, Ahmad⋅Amaro, Rommie⋅Amaro, Rommie⋅Korc, Murray⋅Korc, Murray⋅Zhang, Zhong-Yin⋅Zhang, Zhong Yin⋅Lu, Tao and Lu, Tao
Oncotarget, vol. 8, (no. 25), pp. 39963-39977, June 20, 2017. | Journal Article
 
Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases
Prabhu, Lakshmi⋅Prabhu, Lakshmi⋅Chen, Lan⋅Chen, Lan⋅Wei, Han⋅Wei, Han⋅Demir, Özlem⋅Demir, Özlem⋅Safa, Ahmad⋅Safa, Ahmad⋅Zeng, Lifan⋅Zeng, Lifan⋅Amaro, Rommie E⋅Amaro, Rommie E⋅O'Neil, Bert H⋅O'Neil, Bert H⋅Zhang, Zhon-Yin⋅Zhang, Zhon-Yin⋅Lu, Tao and Lu, Tao
Molecular bioSystems, vol. 13, (no. 12), pp. 2520, 2017-Nov-21. | Journal Article
 
Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell-like spheroids, and tumor xenografts through multiple cell signaling pathways.
Bijangi-Vishehsaraei, Khadijeh⋅Bijangi Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Reza Saadatzadeh, M⋅Reza Saadatzadeh, M⋅Reza Saadatzadeh, M⋅Reza Saadatzadeh, M⋅Reza Saadatzadeh, M⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Nguyen, Angie⋅Nguyen, Angie⋅Nguyen, Angie⋅Nguyen, Angie⋅Nguyen, Angie⋅Kamocka, Malgorzata M⋅Kamocka, Malgorzata M⋅Kamocka, Malgorzata M⋅Kamocka, Malgorzata M⋅Kamocka, Malgorzata M⋅Cai, Wenjing⋅Cai, Wenjing⋅Cai, Wenjing⋅Cai, Wenjing⋅Cai, Wenjing⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen Gadol, Aaron A⋅Halum, Stacey L⋅Halum, Stacey L⋅Halum, Stacey L⋅Halum, Stacey L⋅Halum, Stacey L⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R and Safa, Ahmad R
Journal of neurosurgery, pp. 1-12, January 6, 2017. | Journal Article
2016
Microarray Analysis Gene Expression Profiles in Laryngeal Muscle After Recurrent Laryngeal Nerve Injury
Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Blum, Kevin⋅Blum, Kevin⋅Zhang, Hongji⋅Zhang, Hongji⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Halum, Stacey L and Halum, Stacey L
Annals of Otology, Rhinology & Laryngology, vol. 125, (no. 3), pp. 256, 20160300. | Journal Article
 
Resistance to Cell Death and Its Modulation in Cancer Stem Cells.
Safa, Ahmad R
Critical reviews in oncogenesis, vol. 21, (no. 3-4), pp. 203-219, 2016. | Journal Article
2015
Abstract B18: Targeting histone deacetylase 6 (HDAC6) depresses proliferation and induces caspase-associated cell death in glioblastoma multiforme (GBM) cells and GBM stem cell-like spheroids
Saadatzadeh, Mohammad Reza⋅Saadatzadeh, Mohammad Reza⋅Saadatzadeh, Mohammad Reza⋅Saadatzadeh, Mohammad Reza⋅Vishehsaraei, Khadijeh Bijangi⋅Vishehsaraei, Khadijeh Bijangi⋅Vishehsaraei, Khadijeh Bijangi⋅Vishehsaraei, Khadijeh Bijangi⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Cohen-Gadol, Aaron⋅Cohen-Gadol, Aaron⋅Cohen-Gadol, Aaron⋅Cohen Gadol, Aaron⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R and Safa, Ahmad R
Cancer Research, vol. 75, (no. 23 Supplement), pp. B18, 2015-12-01. | Journal Article
 
Emerging targets for glioblastoma stem cell therapy.
Safa, Ahmad R⋅Saadatzadeh, Mohammad Reza⋅Cohen-Gadol, Aaron A⋅Pollok, Karen E and Bijangi-Vishehsaraei, Khadijeh
Journal of biomedical research, vol. 30, September 20, 2015. | Journal Article
 
Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs.
Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Saadatzadeh, Mohammad Reza⋅Saadatzadeh, Mohammad Reza⋅Saadatzadeh, Mohammad Reza⋅Saadatzadeh, Mohammad Reza⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen Gadol, Aaron A⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh and Bijangi Vishehsaraei, Khadijeh
Genes & Diseases, vol. 2, (no. 2), pp. 152-163, June 2015. | Journal Article
 
Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model
Tonsing-Carter, E.⋅Tonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, B.J.⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Saadatzadeh, M.R.⋅Ding, Jixin⋅Ding, Jixin⋅Ding, Jixin⋅Ding, J.⋅Ding, Jixin⋅Ding, Jixin⋅Ding, Jixin⋅Ding, Jixin⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, H.⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Sinn, A.L.⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Peterman, Kacie M⋅Peterman, Kacie M⋅Peterman, Kacie M⋅Peterman, Kacie M⋅Peterman, Kacie M⋅Peterman, K.M.⋅Peterman, Kacie M⋅Peterman, Kacie M⋅Spragins, Tiaishia K⋅Spragins, Tiaishia K⋅Spragins, Tiaishia K⋅Spragins, T.K.⋅Spragins, Tiaishia K⋅Spragins, Tiaishia K⋅Spragins, Tiaishia K⋅Spragins, Tiaishia K⋅Silver, Jayne M⋅Silver, Jayne M⋅Silver, Jayne M⋅Silver, Jayne M⋅Silver, Jayne M⋅Silver, J.M.⋅Silver, Jayne M⋅Silver, Jayne M⋅Sprouse, Alyssa A⋅Sprouse, Alyssa A⋅Sprouse, Alyssa A⋅Sprouse, A.A.⋅Sprouse, Alyssa A⋅Sprouse, Alyssa A⋅Sprouse, Alyssa A⋅Sprouse, Alyssa A⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, T.M.⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Gunter, T Zachary⋅Gunter, T Zachary⋅Gunter, T Zachary⋅Gunter, T.Z.⋅Gunter, T Zachary⋅Gunter, T Zachary⋅Gunter, T Zachary⋅Gunter, T Zachary⋅Long, Eric C⋅Long, E.C.⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Minto, Robert E⋅Minto, Robert E⋅Minto, Robert E⋅Minto, R.E.⋅Minto, Robert E⋅Minto, Robert E⋅Minto, Robert E⋅Minto, Robert E⋅Marchal, Christophe C⋅Marchal, Christophe C⋅Marchal, C.C.⋅Marchal, Christophe C⋅Marchal, Christophe C⋅Marchal, Christophe C⋅Marchal, Christophe C⋅Marchal, Christophe C⋅Batuello, Christopher N⋅Batuello, Christopher N⋅Batuello, Christopher N⋅Batuello, Christopher N⋅Batuello, Christopher N⋅Batuello, Christopher N⋅Batuello, Christopher N⋅Batuello, C.N.⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, A.R.⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Hanenberg, Helmut⋅Hanenberg, H.⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Territo, P.R.⋅Territo, Paul R⋅Territo, Paul R⋅Sandusky, G.E.⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Mayo, L.D.⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Eischen, Christine M⋅Eischen, Christine M⋅Eischen, Christine M⋅Eischen, Christine M⋅Eischen, Christine M⋅Eischen, Christine M⋅Eischen, C.M.⋅Eischen, Christine M⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Shannon, H.E.⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, K.E.⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E and Pollok, Karen E
Molecular cancer therapeutics, vol. 14, (no. 12), pp. 2863, 2015-Dec. | Journal Article
2014
Abstract 2267: Sulforaphane depresses proliferation and induces cell death in glioblastoma multiforme (GBM) cells, GBM stem cell-like spheroids, and tumor xenografts through modulation of multiple cell signaling pathways
Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Saadatzadeh, Mohammad R⋅Saadatzadeh, Mohammad R⋅Saadatzadeh, Mohammad R⋅Saadatzadeh, Mohammad R⋅Saadatzadeh, Mohammad R⋅Saadatzadeh, Mohammad R⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Kamocka, Malgorzata M⋅Kamocka, Malgorzata M⋅Kamocka, Malgorzata M⋅Kamocka, Malgorzata M⋅Kamocka, Malgorzata M⋅Kamocka, Malgorzata M⋅Cai, Wenjing⋅Cai, Wenjing⋅Cai, Wenjing⋅Cai, Wenjing⋅Cai, Wenjing⋅Cai, Wenjing⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen Gadol, Aaron A⋅Halum, Stacey L⋅Halum, Stacey L⋅Halum, Stacey L⋅Halum, Stacey L⋅Halum, Stacey L⋅Halum, Stacey L⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R and Safa, Ahmad R
Cancer Research, vol. 74, (no. 19 Supplement), pp. 2267, 2014-10-01. | Journal Article
2013
Roles of c-FLIP in Apoptosis, Necroptosis, and Autophagy.
Safa, Ahmad R
Journal of carcinogenesis & mutagenesis, vol. Suppl6, 2013. | Journal Article
2012
c-FLIP, a master anti-apoptotic regulator.
Safa, Ahmad R
Experimental oncology, vol. 34, (no. 3), pp. 176-84, 2012/Oct. | Journal Article
 
Human GM3 Synthase Attenuates Taxol-Triggered Apoptosis Associated with Downregulation of Caspase-3 in Ovarian Cancer Cells.
Huang, Su⋅Huang, Su⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Saadatzadeh, Mohammad Reza⋅Saadatzadeh, Mohammad Reza⋅Safa, Ahmad R and Safa, Ahmad R
Journal of cancer therapy, vol. 3, (no. 5), pp. 504-510, October 2012. | Journal Article
2011
Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy
Safa, Ahmad and Pollok, Karen
(pp. 1639-1671). 2011
2010
4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide (CMH) targets mRNA of the c-FLIP variants and induces apoptosis in MCF-7 human breast cancer cells
Bijangi-Vishehsaraei, Khadijeh⋅Bijangi Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Saadatzadeh, Mohammad⋅Saadatzadeh, Mohammad R⋅Saadatzadeh, Mohammad⋅Huang, Su⋅Huang, Su⋅Huang, Su⋅Murphy, Michael P⋅Murphy, Michael⋅Murphy, Michael⋅Safa, Ahmad R⋅Safa, Ahmad and Safa, Ahmad
Molecular and Cellular Biochemistry, vol. 342, (no. 1-2), pp. 133-142, 2010. | Journal Article
 
Selective TRAIL-triggered apoptosis due to overexpression of TRAIL death receptor 5 (DR5) in P-glycoprotein-bearing multidrug resistant CEM/VBL1000 human leukemia cells.
Park, Soo-Jung⋅Park, Soo-Jung⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi Vishehsaraei, Khadijeh⋅Safa, Ahmad R and Safa, Ahmad R
International journal of biochemistry and molecular biology, vol. 1, (no. 1), pp. 90-100, 2010. | Journal Article
2009
c-FLIP gene silencing eliminates tumor cells in breast cancer xenografts without affecting stromal cells.
DAY, TRAVIS⋅Day, Travis W⋅Sinn, Anthony L⋅SINN, ANTHONY⋅Huang, Su⋅HUANG, SU⋅Pollok, Karen E⋅POLLOK, KAREN⋅Sandusky, George E⋅Sandusky, George⋅SAFA, AHMAD and Safa, Ahmad R
Anticancer research, vol. 29, (no. 10), pp. 3883-6, 2009/Oct. | Journal Article
 
Dynamic assessment of mitoxantrone resistance and modulation of multidrug resistance by valspodar (PSC833) in multidrug resistance human cancer cells.
Shen, Fei⋅Bailey, Barbara J⋅Chu, Shaoyou⋅Bence, Aimee K⋅Xue, Xinjian⋅Erickson, Priscilla⋅Safa, Ahmad R⋅Beck, William T and Erickson, Leonard C
The Journal of pharmacology and experimental therapeutics, vol. 330, (no. 2), pp. 423-9, 2009/Aug. | Journal Article
 
Etoposide induces protein kinase Cdelta- and caspase-3-dependent apoptosis in neuroblastoma cancer cells.
Day, Travis W⋅Wu, Ching-Huang and Safa, Ahmad R
Molecular pharmacology, vol. 76, (no. 3), pp. 632-40, 2009/Sep. | Journal Article
 
Human beta-galactoside alpha-2,3-sialyltransferase (ST3Gal III) attenuated Taxol-induced apoptosis in ovarian cancer cells by downregulating caspase-8 activity.
Huang, Su⋅Day, Travis W⋅Choi, Mi Ran and Safa, Ahmad R
Molecular and cellular biochemistry, vol. 331, (no. 1-2), pp. 81-8, 2009/Nov. | Journal Article
 
Human β-galactoside α-2,3-sialyltransferase (ST3Gal III) attenuated Taxol-induced apoptosis in ovarian cancer cells by downregulating caspase-8 activity
Huang, Su⋅Day, Travis W⋅Choi, Mi Ran and Safa, Ahmad R
Molecular and cellular biochemistry., vol. 331, (no. 1-2), pp. 81-88, 2009. | Journal Article
 
RNA Interference in Cancer: Targeting the Anti-Apoptotic Protein c-FLIP for Drug Discovery
Day, Travis W and Safa, Ahmad R
Mini-Reviews in Medicinal Chemistry, vol. 9, (no. 6), pp. 741-748, 2009. | Journal Article