94 Publications (Page 2 of 4)
2009
The Xpc gene markedly affects cell survival in mouse bone marrow.
Fischer, Joshua L⋅Fischer, Joshua L⋅Kumar, M.A. Suresh⋅Kumar, M A⋅Day, Travis W⋅Day, Travis W⋅Hardy, Tabitha M⋅Hardy, Tabitha M⋅Hamilton, Shari⋅Hamilton, Shari⋅Besch-Williford, Cynthia⋅Besch-Williford, Cynthia⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Pollok, Karen E⋅Pollok, Karen E⋅Smith, Martin L and Smith, Martin L
Mutagenesis, vol. 24, (no. 4), pp. 309-16, 2009/Jul. | Journal Article
2008
Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI
Choi, Mi Ran⋅Najafi, Farhad⋅Safa, Ahmad R and Drexler, Hannes C
Biochemical Pharmacology, vol. 75, (no. 12), pp. 2276-2288, 2008. | Journal Article
 
Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy.
Safa, Ahmad R⋅Day, Travis W and Wu, Ching-Huang
Current cancer drug targets, vol. 8, (no. 1), pp. 37-46, 2008/Feb. | Journal Article
 
c-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells
Day, Travis W⋅Huang, Su and Safa, Ahmad R
Biochemical Pharmacology, vol. 76, (no. 12), pp. 1694-1704, 2008. | Journal Article
 
TRAIL Recombinant Adenovirus Triggers Robust Apoptosis in Multidrug-Resistant HL-60/Vinc Cells Preferentially Through Death Receptor DR5
Wu, C-H⋅Wu, Ching⋅Kao, C-H⋅Kao, Chinghai⋅Safa, Ahmad R and Safa, Ahmad R
Human Gene Therapy, vol. 19, (no. 7), pp. 731-743, 2008. | Journal Article
2007
Phosphorylation of RNA Helicase A by DNA-Dependent Protein Kinase Is Indispensable for Expression of the MDR1 Gene Product P-Glycoprotein in Multidrug-Resistant Human Leukemia Cells
Zhong, Xiaoling and Safa, Ahmad R
Biochemistry, vol. 46, (no. 19), pp. 5775, 20070515. | Journal Article
2006
Cellular FLICE-like inhibitory protein (c-FLIP): a novel target for Taxol-induced apoptosis.
Day, Travis W⋅Najafi, Farhad⋅Wu, Ching-Huang and Safa, Ahmad R
Biochemical pharmacology, vol. 71, (no. 11), pp. 1551-1561, May 28, 2006. | Journal Article
 
Cellular FLICE-like inhibitory protein (c-FLIP): A novel target for Taxol- induced apoptosis
Day, Travis W⋅Najafi, Farhad⋅Wu, Ching-Huang and Safa, Ahmad R
Biochemical Pharmacology, vol. 71, (no. 11), pp. 1551-1561, 2006. | Journal Article
 
P-glycoprotein enhances TRAIL-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5.
Park, Soo-Jung⋅Wu, Ching-Huang⋅Choi, Mi Ran⋅Najafi, Farhad⋅Emami, Armaghan and Safa, Ahmad R
Biochemical pharmacology, vol. 72, (no. 3), pp. 293-307, 2006/Jul/28. | Journal Article
2004
A P-glycoprotein- and MRP1-independent doxorubicin-resistant variant of the MCF-7 breast cancer cell line with defects in caspase-6, -7, -8, -9 and -10 activation pathways.
Park, Soo-Jung⋅Wu, Ching-Haung and Safa, Ahmad R
Anticancer research, vol. 24, (no. 1), pp. 123-31, 2004 Jan-Feb. | Journal Article
 
Identification and characterization of the binding sites of P-glycoprotein for multidrug resistance-related drugs and modulators.
Safa, Ahmad R
Current medicinal chemistry. Anti-cancer agents. , vol. 4, (no. 1), pp. 1-17, 2004/Jan. | Journal Article
 
RNA helicase A in the MEF1 transcription factor complex up-regulates the MDR1 gene in multidrug-resistant cancer cells.
Zhong, Xiaoling⋅Zhong, Xiaoling⋅Safa, Ahmad R and Safa, Ahmad R
The Journal of biological chemistry, vol. 279, (no. 17), pp. 17134-41, 2004/Apr/23. | Journal Article
 
Taxol induces caspase-10-dependent apoptosis.
Park, Soo-Jung⋅Wu, Ching-Haung⋅Gordon, John D⋅Zhong, Xiaoling⋅Emami, Armaghan and Safa, Ahmad R
The Journal of biological chemistry, vol. 279, (no. 49), pp. 51057-67, 2004/Dec/3. | Journal Article
 
Taxol Induces Caspase-10-dependent Apoptosis
Park, Soo-Jung⋅Wu, Ching-Haung⋅Gordon, John⋅Zhong, Xiaoling⋅Emami, Armaghan and Safa, Ahmad
Journal of Biological Chemistry, vol. 279, (no. 49), pp. 51067, 20041203. | Journal Article
2003
Beta2-microglobulin induces caspase-dependent apoptosis in the CCRF-HSB-2 human leukemia cell line independently of the caspase-3, -8 and -9 pathways but through increased reactive oxygen species.
Gordon, John⋅Wu, Ching-Huang⋅Rastegar, Mojgan and Safa, Ahmad R
International journal of cancer. Journal international du cancer, vol. 103, (no. 3), pp. 316-27, 2003/Jan/20. | Journal Article
 
β2‐microglobulin induces caspase‐dependent apoptosis in the CCRF‐HSB‐2 human leukemia cell line independently of the caspase‐3, ‐8 and ‐9 pathways but through increased reactive oxygen species
Gordon, John⋅Wu, Ching‐Huang⋅Rastegar, Mojgan and Safa, Ahmad R
International Journal of Cancer, vol. 103, (no. 3), pp. 327, 20 January 2003. | Journal Article
2002
Irinotecan and gemcitabine in patients with solid tumors: phase I trial
Rocha Lima, Caio Max⋅Rocha Lima, Caio Max⋅Lima, Caio M⋅Leong, Swan-Swan⋅Leong, Swan-Swan⋅Sherman, Carol A⋅Sherman, Carol A⋅Perkel, Joshua A⋅Perkel, Joshua A⋅Putman, Terri⋅Putman, Terri⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Green, Mark R and Green, Mark R
Oncology (Williston Park, N.Y.), vol. 16, (no. 5 Suppl 5), pp. 19, 2002-May. | Journal Article
 
Mechanism of beta 2-microglobulin-induced apoptosis in the K562 leukemia cell line, defective in major histocompatibility class 1.
Wu, Ching-Huang⋅Gordon, John D⋅Zhong, Xiaoling and Safa, Ahmad R
Anticancer Research, vol. 22, (no. 5), pp. 2613-21, 2002 Sep-Oct. | Journal Article
 
Proteinase-3, a serine protease which mediates doxorubicin-induced apoptosis in the HL-60 leukemia cell line, is downregulated in its doxorubicin-resistant variant
Wu, C-H⋅Gordon, J.⋅Rastegar, M.⋅Ogretmen, Besim and Safa, Ahmad R
Oncogene, vol. 21, (no. 33), pp. 5160-5174, 2002. | Journal Article
2001
[beta]2-microglobulin induces apoptosis in HL-60 human leukemia cell line and its multidrug resistant variants overexpressing MRP1 but lacking Bax or overexpressing P-glycoprotein
Wu, Ching-Huang⋅Rastegar, Mojgan⋅Gordon, John and Safa, Ahmad R
Oncogene, vol. 20, (no. 48), pp. 7006-20, Oct 25, 2001. | Journal Article
 
beta sub(2)-microglobulin induces apoptosis in HL-60 human leukemia cell line and its multidrug resistant variants overexpressing MRP1 but lacking Bax or overexpressing P-glycoprotein
Wu, Ching-Huang⋅Rastegar, M.⋅Gordon, J. and Safa, Ahmad R
Oncogene, vol. 20, (no. 48), pp. 7006-7020, 2001. | Journal Article
2000
Identification and characterization of the MDR1 promoter-enhancing factor 1 (MEF1) in the multidrug resistant HL60/VCR human acute myeloid leukemia cell line.
Ogretmen, Besim and Safa, Ahmad R
Biochemistry, vol. 39, (no. 1), pp. 194-204, 2000/Jan/11. | Journal Article
1999
Modulation of Multidrug Resistance in Cancer Cells by Inhibitors of P-Glycoprotein
Safa, Ahmad
CHIMIA International Journal for Chemistry, vol. 53, (no. 6), pp. 299, June 1999. | Journal Article
 
Negative regulation of MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross-coupled NF-B/p65 and c-Fos transcription factors and their interaction with the CAAT region
Ogretman, Besim and Safa, Ahmad
Biochemistry, vol. 38, (no. 7), pp. 2189, 19990216. | Journal Article
 
Negative Regulation of MDR1 Promoter Activity in MCF-7, but Not in Multidrug Resistant MCF-7/Adr, Cells by Cross-Coupled NF-κB/p65 and c-Fos Transcription Factors and Their Interaction with the CAAT Region
Ogretmen, Besim and Safa, Ahmad R
Biochemistry, vol. 38, (no. 7), pp. 2199, 19990216. | Journal Article