9 Publications
2005
Synthesis and preliminary biological evaluation of O6-[4-(2-[18F]fluoroethoxymethyl)benzyl]guanine as a novel potential PET probe for the DNA repair protein O6-alkylguanine-DNA alkyltransferase in cancer chemotherapy.
Wang, Ji-Quan⋅Kreklau, Emiko L⋅Bailey, Barbara J⋅Erickson, Leonard C and Zheng, Qi-Huang
Bioorganic & medicinal chemistry, vol. 13, (no. 20), pp. 5779-86, 2005/Oct/15. | Journal Article
 
Synthesis and preliminary biological evaluation of O super(6)-[4-(2- [ super(18)F]fluoroethoxymethyl)benzyl]guanine as a novel potential PET probe for the DNA repair protein O super(6)-alkylguanine-DNA alkyltransferase in cancer chemotherapy
Wang, Ji-Quan⋅Wang, Ji-Quan⋅Kreklau, Emiko L⋅Kreklau, Emiko⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Erickson, Leonard C⋅Erickson, Leonard C⋅Zheng, Qi-Huang and Zheng, Qi Huang
Bioorganic and Medicinal Chemistry, vol. 13, (no. 20), pp. 5779-5786, 2005. | Journal Article
2003
Delayed repletion of O6-methylguanine-DNA methyltransferase resulting in failure to protect the human glioblastoma cell line SF767 from temozolomide-induced cytotoxicity.
Hirose, Yuichi⋅Kreklau, Emiko L⋅Erickson, Leonard C⋅Berger, Mitchel S and Pieper, Russell O
Journal of neurosurgery, vol. 98, (no. 3), pp. 591-8, 2003/Mar. | Journal Article
 
Hematopoietic expression of O(6)-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O(6)-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea.
Kreklau, Emiko L⋅Pollok, Karen E⋅Bailey, Barbara J⋅Liu, Naili⋅Hartwell, Jennifer R⋅Williams, David A and Erickson, Leonard C
Molecular Cancer Therapeutics, vol. 2, (no. 12), pp. 1321-9, 2003/Dec. | Journal Article
 
In Vivo Selection of Human Hematopoietic Cells in a Xenograft Model Using Combined Pharmacologic and Genetic Manipulations
Pollok, Karen E⋅Hartwell, J. R⋅Braber, A.⋅Cooper, RJ⋅Jansen, M.⋅Ragg, Susanne⋅Bailey, BJ⋅Erickson, Leonard C⋅Kreklau, Emiko and Williams, David A
Human Gene Therapy, vol. 14, (no. 18), pp. 1703-1714, 2003. | Journal Article
 
O6-methylguanine-DNA-methyltransferase expression and gene polymorphisms in relation to chemotherapeutic response in metastatic melanoma.
Ma, S⋅Egyházi, S⋅Ueno, T⋅Lindholm, C⋅Kreklau, Emiko L⋅Stierner, Ulrika⋅Ringborg, U and Hansson, J
British Journal of Cancer, vol. 89, (no. 8), pp. 1517-23, 2003/Oct/20. | Journal Article
2001
A novel fluorometric oligonucleotide assay to measure O6-methylguanine DNA methyltransferase, methylpurine DNA glycosylase, 8-oxoguanine DNA glycosylase and abasic endonuclease activities: DNA repair status in human breast carcinoma cells overexpressing methylpurine DNA glycosylase
Kreklau, Emiko⋅Kreklau, Emiko⋅Limp-Foster, Melissa⋅Limp-Foster, Melissa⋅Liu, Naili⋅Liu, Naili⋅Xu, Yi⋅Xu, Yi⋅Kelley, Mark⋅Kelley, Mark R⋅Erickson, Leonard and Erickson, Leonard C
Nucleic Acids Research, vol. 29, (no. 12), pp. 2558, Jun 15, 2001. | Journal Article
 
A novel fluorometric oligonucleotide assay to measure O super(6)-methylguanine DNA methyltransferase, methylpurine DNA glycosylase, 8-oxoguanine DNA glycosylase and abasic endonuclease activities: DNA repair status in human breast carcinoma cells overexpressing methylpurine DNA glycosylase
Kreklau, Emiko⋅Kreklau, Emiko L⋅Limp-Foster, M.⋅Limp-Foster, Melissa⋅Liu, N.⋅Liu, Naili⋅Xu, Yi⋅Xu, Y.⋅Kelley, MR⋅Kelley, Mark R⋅Erickson, Leonard C and Erickson, Leonard C
Nucleic Acids Research, vol. 29, (no. 12), pp. 2558-2566, 2001. | Journal Article
1999
Nitric oxide inhibits human aldosteronogenesis without guanylyl cyclase stimulation.
Kreklau, Emiko L⋅Carlson, E J and Drewett, J G
Molecular and cellular endocrinology, vol. 153, (no. 1-2), pp. 103-11, 1999/Jul/20. | Journal Article