34 Publications (Page 1 of 2)
2013
Structural basis for 2?-phosphate incorporation into glycogen by glycogen synthase
Chikwana, Vimbai M⋅Chikwana, Vimbai⋅Khanna, May⋅Khanna, May⋅Baskaran, Sulochanadevi⋅Baskaran, Sulochanadevi⋅Tagliabracci, Vincent S⋅Tagliabracci, Vincent⋅Contreras, Christopher J⋅Contreras, Christopher⋅DePaoli-Roach, Anna⋅Depaoli Roach, Anna A⋅DePaoli-Roach, Anna⋅Roach, Peter⋅Roach, Peter J⋅Hurley, Thomas D and Hurley, Thomas
Proceedings of the National Academy of Sciences of the United States of America, vol. 110, (no. 52), Dec 24, 2013. | Journal Article
2012
Glycogen and its metabolism: some new developments and old themes.
Roach, Peter J⋅Roach, Peter J⋅Depaoli-Roach, Anna A⋅Depaoli Roach, Anna A⋅Hurley, Thomas D⋅Hurley, Thomas D⋅Tagliabracci, Vincent S and Tagliabracci, Vincent S
The Biochemical journal, vol. 441, (no. 3), pp. 763-87, 2012/Feb/1. | Journal Article
 
Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity
DePaoli-Roach, A.A.⋅DePaoli-Roach, Anna A⋅DePaoli-Roach, Anna A⋅Depaoli Roach, Anna A⋅Segvich, Dyann M⋅Segvich, Dyann M⋅Segvich, D.M.⋅Meyer, C.M.⋅Meyer, Catalina M⋅Meyer, Catalina M⋅Rahimi, Yasmeen⋅Rahimi, Y.⋅Rahimi, Yasmeen⋅Worby, Carolyn A⋅Worby, Carolyn A⋅Worby, C.A.⋅Gentry, Matthew⋅Gentry, M.S.⋅Gentry, Matthew S⋅Roach, Peter J⋅Roach, P.J. and Roach, Peter J
Human Molecular Genetics, vol. 21, (no. 7), pp. 1604-1610, 2012. | Journal Article
2011
Multiple glycogen-binding sites in eukaryotic glycogen synthase are required for high catalytic efficiency toward glycogen.
Baskaran, Sulochanadevi⋅Chikwana, Vimbai M⋅Contreras, Christopher J⋅Davis, Keri D⋅Wilson, Wayne A⋅DePaoli-Roach, Anna A⋅Depaoli Roach, Anna A⋅Roach, Peter J and Hurley, Thomas D
The Journal of biological chemistry, vol. 286, (no. 39), pp. 33999-4006, 2011/Sep/30. | Journal Article
 
Phosphate incorporation during glycogen synthesis and Lafora disease.
Tagliabracci, Vincent S⋅Tagliabracci, V.S.⋅Heiss, C.⋅Heiss, Christian⋅Karthik, C.⋅Karthik, Chandra⋅Contreras, C.J.⋅Contreras, Christopher J⋅Glushka, John⋅Glushka, J.⋅Ishihara, M.⋅Ishihara, Mayumi⋅Azadi, P.⋅Azadi, Parastoo⋅Hurley, Thomas D⋅Hurley, T.D.⋅DePaoli-Roach, Anna A⋅Depaoli-Roach, A.A.⋅Depaoli Roach, Anna A⋅Roach, Peter J and Roach, P.J.
Cell metabolism, vol. 13, (no. 3), pp. 274-82, 2011/Mar/2. | Journal Article
 
PTG depletion removes Lafora bodies and rescues the fatal epilepsy of Lafora disease.
Turnbull, Julie⋅Depaoli Roach, Anna A⋅Zhao, Xiaochu⋅Cortez, Miguel A⋅Pencea, Nela⋅Tiberia, Erica⋅Piliguian, Mark⋅Roach, Peter J⋅Wang, Peixiang⋅Ackerley, Cameron and Minassian, Berge
PLoS genetics, vol. 7, (no. 4), pp. e1002037, 2011/Apr. | Journal Article
2010
Basis for MAP4 dephosphorylation-related microtubule network densification in pressure overload cardiac hypertrophy.
Cheng, Guangmao⋅Takahashi, Masaru⋅Shunmugavel, Anandakumar⋅Wallenborn, J G⋅Depaoli Roach, Anna A⋅Gergs, Ulrich⋅Neumann, Joachim⋅Kuppuswamy, Dhandapani⋅Menick, Donald R and Cooper, George
The Journal of biological chemistry, vol. 285, (no. 49), pp. 38125-40, 2010/Dec/3. | Journal Article
 
Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin
Depaoli Roach, Anna A⋅DePaoli-Roach, Anna A⋅DePaoli-Roach, Anna A⋅Tagliabracci, Vincent S⋅Tagliabracci, Vincent S⋅Segvich, Dyann M⋅Segvich, Dyann M⋅Meyer, Catalina M⋅Meyer, Catalina M⋅Irimia, Jose M⋅Irimia, Jose M⋅Roach, Peter J and Roach, Peter J
Journal of Biological Chemistry, vol. 285, (no. 33), pp. 25372-25381, 2010. | Journal Article
 
Impaired Glucose Tolerance and Predisposition to the Fasted State in Liver Glycogen Synthase Knock-out Mice.
Irimia, Jose M⋅Meyer, Catalina M⋅Peper, Caron L⋅Zhai, Lanmin⋅Bock, Cheryl B⋅Previs, Stephen F⋅McGuinness, Owen P⋅Depaoli Roach, Anna A⋅DePaoli-Roach, Anna and Roach, Peter J
Journal of biological chemistry., vol. 285, (no. 17), pp. 12851-12861, 2010. | Journal Article
 
Starch Binding Domain-containing Protein 1/Genethonin 1 Is a Novel Participant in Glycogen Metabolism
Jiang, Sixin⋅Heller, Brigitte⋅Tagliabracci, Vincent S⋅Zhai, Lanmin⋅Irimia, Jose M⋅Depaoli Roach, Anna A⋅DePaoli-Roach, Anna A⋅Wells, Clark D⋅Skurat, Alexander V and Roach, Peter J
Journal of Biological Chemistry, vol. 285, (no. 45), pp. 34960-34971, 2010. | Journal Article
 
Structural basis for glucose-6-phosphate activation of glycogen synthase
Baskaran, Sulochanadevi⋅Baskaran, Sulochanadevi⋅Roach, Peter⋅Roach, Peter J⋅Depaoli Roach, Anna A⋅DePaoli-Roach, Anna⋅DePaoli-Roach, Anna A⋅Hurley, Thomas D and Hurley, Thomas
Proceedings of the National Academy of Sciences of the United States of America, vol. 107, (no. 41), Oct 12, 2010. | Journal Article
2009
Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A.
Eckerdt, Frank⋅Eckerdt, Frank⋅Pascreau, Gaetan⋅Pascreau, Gaetan⋅Phistry, Meridee⋅Phistry, Meridee⋅Lewellyn, Andrea L⋅Lewellyn, Andrea L⋅Depaoli Roach, Anna A⋅DePaoli-Roach, Anna A⋅Maller, James L and Maller, James L
Cell cycle (Georgetown, Tex.), vol. 8, (no. 15), pp. 2413-9, 2009/Aug. | Journal Article
2008
Abnormal metabolism of glycogen phosphate as a cause for Lafora disease.
Tagliabracci, Vincent⋅Tagliabracci, Vincent S⋅Girard, Jean⋅Girard, Jean M⋅Segvich, Dyann⋅Segvich, Dyann⋅Meyer, Catalina⋅Meyer, Catalina⋅Turnbull, Julie⋅Turnbull, Julie⋅Zhao, Xiaochu⋅Zhao, Xiaochu⋅Minassian, Berge⋅Minassian, Berge⋅DePaoli-Roach, Anna⋅Depaoli Roach, Anna A⋅Roach, Peter J and Roach, Peter
The Journal of biological chemistry, vol. 283, (no. 49), pp. 33816-25, 2008/Dec/5. | Journal Article
 
A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.
Savage, David A⋅Zhai, Lanmin⋅Ravikumar, Balasubramanian⋅Cheol, S.C.⋅Choi, Cheol S⋅Snaar, Johanna E⋅McGuire, Amanda C⋅Wou, Sung-Eun⋅Medina-Gomez, Gemma⋅Kim, Sheene⋅Bock, Cheryl B⋅Segvich, Dyann M⋅Vidal Puig, Antonio⋅Solanky, Bhavana⋅Wareham, Nicholas J⋅Deelchand, Dinesh⋅Shulman, Gerald I⋅Karpe, Fredrik⋅Taylor, Roy⋅Pederson, Bartholomew A⋅Roach, Peter J⋅O’Rahilly, S.⋅O'Rahilly, Stephen⋅Depaoli Roach, Anna A and DePaoli-Roach, A.A.
PLoS medicine, vol. 5, (no. 1), pp. e27, 2008/Jan/29. | Journal Article
 
Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality
Brüchert, Nicole⋅Mavila, Nirmala⋅Boknik, Peter⋅Baba, Hideo A⋅Fabritz, Larissa⋅Gergs, Ulrich⋅Kirchhefer, Uwe⋅Kirchhof, Paulus⋅Matus, Marek⋅Schmitz, Wilhelm⋅Depaoli Roach, Anna A and Neumann, Joachim
American Journal of Physiology, vol. 295, (no. 4), Oct 2008. | Journal Article
2007
Glycogen metabolism in tissues from a mouse model of Lafora disease.
Wang, Wei⋅Wang, Wei⋅Lohi, Hannes⋅Lohi, Hannes⋅Skurat, Alexander V⋅Skurat, Alexander V⋅DePaoli-Roach, Anna A⋅Depaoli Roach, Anna A⋅DePaoli-Roach, Anna A⋅Minassian, Berge A⋅Minassian, Berge A⋅Roach, Peter J and Roach, Peter J
Archives of biochemistry and biophysics, vol. 457, (no. 2), pp. 264-9, 2007/Jan/15. | Journal Article
 
Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo
Tagliabracci, Vincent⋅Delgado Escueta, Antonio⋅Tagliabracci, Vincent S⋅Turnbull, Julie⋅Turnbull, Julie⋅Wang, Wei⋅Wang, Wei⋅Girard, Jean-Marie⋅Girard, Jean-Marie⋅Zhao, Xiaochu⋅Zhao, Xiaochu⋅Skurat, Alexander⋅Skurat, Alexander V⋅Delgado-Escueta, Antonio⋅Delgado-Escueta, Antonio V⋅Minassian, Berge⋅Minassian, Berge⋅Depaoli Roach, Anna A⋅DePaoli-Roach, Anna⋅Roach, Peter J and Roach, Peter
Proceedings of the National Academy of Sciences of the United States of America, vol. 104, (no. 49), Dec 4, 2007. | Journal Article
 
Structural basis for regulation of protein phosphatase 1 by inhibitor-2.
Hurley, Thomas D⋅Yang, Jie⋅Zhang, Lili⋅Goodwin, Kristie D⋅Zou, Qin⋅Cortese, Marc⋅Dunker, A K and Depaoli Roach, Anna A
The Journal of biological chemistry, vol. 282, (no. 39), pp. 28874-83, 2007/Sep/28. | Journal Article
2006
Relationship between glycogen accumulation and the laforin dual specificity phosphatase.
Wang, Wei⋅Wang, Wei⋅Parker, Gretchen E⋅Parker, Gretchen E⋅Skurat, Alexander V⋅Skurat, Alexander V⋅Raben, Nina⋅Raben, Nina⋅Depaoli Roach, Anna A⋅DePaoli-Roach, Anna A⋅DePaoli-Roach, Anna A⋅Roach, Peter J and Roach, Peter J
Biochemical and biophysical research communications, vol. 350, (no. 3), pp. 588-92, 2006/Nov/24. | Journal Article
2005
Enhanced cardiac function in mice overexpressing protein phosphatase Inhibitor-2.
Kirchhefer, Uwe⋅Baba, Hideo A⋅Bokník, Peter⋅Breeden, Kristine M⋅Mavila, Nirmala⋅Brüchert, Nicole⋅Justus, Isabel⋅Matus, Marek⋅Schmitz, Wilhelm⋅Depaoli Roach, Anna A and Neumann, Joachim
Cardiovascular research, vol. 68, (no. 1), pp. 98-108, 2005/Oct/1. | Journal Article
 
Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1.
Pathak, Anand⋅Pathak, Anand⋅Del Monte, Federica⋅Del Monte, Federica⋅Zhao, Wen⋅Zhao, Wen⋅Schultz, Jo-El⋅Schultz, Jo-El⋅Lorenz, John N⋅Lorenz, John N⋅Bodi, Ilona⋅Bodi, Ilona⋅Weiser, Doug⋅Weiser, Doug⋅Hahn, Harvey⋅Hahn, Harvey⋅Carr, Andrew N⋅Carr, Andrew N⋅Syed, Faisal⋅Syed, Faisal⋅Mavila, Nirmala⋅Mavila, Nirmala⋅Jha, Leena⋅Jha, Leena⋅Qian, Jiang⋅Qian, Jiang⋅Marreez, Yehia⋅Marreez, Yehia⋅Chen, Guoli⋅Chen, Guoli⋅McGraw, Dennis W⋅Mc Graw, Dennis W⋅Heist, E Kevin⋅Heist, E K⋅Guerrero, J Luis⋅Guerrero, J L⋅DePaoli-Roach, Anna A⋅Depaoli Roach, Anna A⋅Hajjar, Roger J⋅Hajjar, Roger J⋅Kranias, Evangela G and Kranias, Evangelia G
Circulation research, vol. 96, (no. 7), pp. 756-66, 2005/Apr/15. | Journal Article
 
Exercise Capacity of Mice Genetically Lacking Muscle Glycogen Synthase: IN MICE, MUSCLE GLYCOGEN IS NOT ESSENTIAL FOR EXERCISE.
Pederson, Bartholomew A⋅Cope, Carlie R⋅Schroeder, Jill M⋅Smith, Micah W⋅Irimia, José M⋅Thurberg, Beth L⋅Depaoli Roach, Anna A and Roach, Peter J
Journal of biological chemistry., vol. 280, (no. 17), pp. 17260-17265, 2005. | Journal Article
 
Glucose Metabolism in Mice Lacking Muscle Glycogen Synthase
Pederson, Bartholomew A⋅Schroeder, Jill M⋅Parker, Gretchen E⋅Smith, Micah W⋅Depaoli Roach, Anna A and Roach, Peter J
Diabetes, vol. 54, (no. 12), pp. 3466-3473, 2005. | Journal Article
 
Mice with elevated muscle glycogen stores do not have improved exercise performance.
Pederson, Bartholomew A⋅Cope, Carlie R⋅Irimia, Jose M⋅Schroeder, Jill M⋅Thurberg, Beth L⋅Depaoli Roach, Anna A and Roach, Peter J
Biochemical and biophysical research communications, vol. 331, (no. 2), pp. 491-6, 2005/Jun/3. | Journal Article
2004
Abnormal cardiac development in the absence of heart glycogen.
Pederson, Bartholomew A⋅Chen, Hanying⋅Schroeder, Jill M⋅Shou, Weinian⋅DePaoli-Roach, Anna A⋅Depaoli Roach, Anna A and Roach, Peter J
Molecular and cellular biology, vol. 24, (no. 16), pp. 7179-87, 2004/Aug. | Journal Article