119 Publications (Page 1 of 5)
2020
Phenotype transitions induced by mechanical stimuli in airway smooth muscle are regulated by differential interactions of parvin isoforms with paxillin and Akt
Huang, Youliang and Gunst, Susan J
American journal of physiology. Lung cellular and molecular physiology, vol. 318, (no. 5), pp. L1055, 2020-May-01. | Journal Article
2019
Molecular Mechanisms for the Mechanical Modulation of Airway Responsiveness
Zhang, Wenwu and Gunst, Susan J
Journal of engineering and science in medical diagnostics and therapy, vol. 2, (no. 1), 2019-Feb. | Journal Article
2018
Effect of CPAP on airway reactivity and airway inflammation in children with moderate-severe asthma.
Praca, Eduardo⋅Praca, Eduardo⋅Praca, Eduardo⋅Praca, Eduardo⋅Jalou, Hasnaa⋅Jalou, Hasnaa⋅Jalou, Hasnaa⋅Jalou, Hasnaa⋅Krupp, Nadia⋅Krupp, Nadia⋅Krupp, Nadia⋅Krupp, Nadia⋅Delecaris, Angela⋅Delecaris, Angela⋅Delecaris, Angela⋅Delecaris, Angela⋅Hatch, Joseph⋅Hatch, Joseph⋅Hatch, Joseph⋅Hatch, Joseph⋅Slaven, James⋅Slaven, James⋅Slaven, James⋅Slaven, James⋅Gunst, Susan J⋅Gunst, Susan J⋅Gunst, Susan J⋅Gunst, Susan J⋅Tepper, Robert S⋅Tepper, Robert S⋅Tepper, Robert S and Tepper, Robert S
Respirology (Carlton, Vic.), November 16, 2018. | Journal Article
 
Elastase alters contractility and promotes an inflammatory synthetic phenotype in airway smooth muscle tissues
Lockett, Angelia D⋅Lockett, Angelia D⋅Wu, Yidi⋅Wu, Yidi⋅Gunst, Susan J and Gunst, Susan J
American journal of physiology. Lung cellular and molecular physiology, vol. 314, (no. 4), pp. L634, 2018-04-01. | Journal Article
 
Rho kinase collaborates with p21‐activated kinase to regulate actin polymerization and contraction in airway smooth muscle
Zhang, Wenwu⋅Zhang, Wenwu⋅Bhetwal, Bhupal P⋅Bhetwal, Bhupal P⋅Gunst, Susan J and Gunst, Susan J
The Journal of Physiology, vol. 596, (no. 16), pp. 3635, 15 August 2018. | Journal Article
2017
Non‐muscle (NM) myosin heavy chain phosphorylation regulates the formation of NM myosin filaments, adhesome assembly and smooth muscle contraction
Zhang, Wenwu⋅Zhang, Wenwu⋅Gunst, Susan J and Gunst, Susan J
The Journal of Physiology, vol. 595, (no. 13), pp. 4300, 1 July 2017. | Journal Article
2016
Focal adhesion kinase (FAK) and mechanical stimulation negatively regulate the transition of airway smooth muscle tissues to a synthetic phenotype.
Wu, Yidi⋅Huang, Youliang and Gunst, Susan J
American journal of physiology. Lung cellular and molecular physiology, vol. 311, (no. 5), pp. L893-L902, November 1, 2016. | Journal Article
 
p21-Activated kinase (Pak) regulates airway smooth muscle contraction by regulating paxillin complexes that mediate actin polymerization.
Zhang, Wenwu⋅Huang, Youliang and Gunst, Susan J
The Journal of physiology, vol. 594, (no. 17), pp. 4879-4900, September 1, 2016. | Journal Article
2015
A novel role for RhoA GTPase in the regulation of airway smooth muscle contraction.
Zhang, Wenwu⋅Zhang, Wenwu⋅Huang, Youliang⋅Huang, Youliang⋅Wu, Yidi⋅Wu, Yidi⋅Gunst, Susan J and Gunst, Susan J
Canadian journal of physiology and pharmacology, vol. 93, (no. 2), pp. 129-136, February 2015. | Journal Article
 
Vasodilator-stimulated phosphoprotein (VASP) regulates actin polymerization and contraction in airway smooth muscle by a vinculin-dependent mechanism.
Wu, Yidi and Gunst, Susan J
The Journal of biological chemistry, vol. 290, (no. 18), pp. 11403-11416, May 1, 2015. | Journal Article
2014
Vinculin phosphorylation at Tyr1065 regulates vinculin conformation and tension development in airway smooth muscle tissues.
Huang, Youliang⋅Day, Richard N and Gunst, Susan J
The Journal of biological chemistry, vol. 289, (no. 6), pp. 3677-3688, February 7, 2014. | Journal Article
2013
Increased mechanical strain imposed on murine lungs during ventilation in vivo depresses airway responsiveness and activation of protein kinase Akt.
Xue, Z⋅Zhang, W⋅Desai, L P⋅Gao, H⋅Gunst, S J and Tepper, R S
Journal of applied physiology (Bethesda, Md. : 1985), vol. 114, (no. 11), pp. 1506-1510, June 2013. | Journal Article
 
Regulation of 130-kDa smooth muscle myosin light chain kinase expression by an intronic CArG element.
Chen, Meng⋅Chen, Meng⋅Zhang, Wenwu⋅Zhang, Wenwu⋅Lu, Xiao⋅Lu, Xiao⋅Hoggatt, April M⋅Hoggatt, April M⋅Gunst, Susan J⋅Gunst, Susan J⋅Kassab, Ghassan S⋅Kassab, Ghassan S⋅Tune, Johnathan D⋅Tune, Johnathan D⋅Herring, B Paul and Herring, B P
The Journal of biological chemistry, vol. 288, (no. 48), pp. 34647-57, 2013/Nov/29. | Journal Article
 
Use of continuous positive airway pressure reduces airway reactivity in adults with asthma.
Busk, Michael⋅Busk, Nancy⋅Puntenney, Paula⋅Hutchins, Janet⋅Yu, Zhangsheng⋅Gunst, Susan J and Tepper, Robert S
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology, vol. 41, (no. 2), pp. 317-22, 2013/Feb. | Journal Article
2012
Altered calcium signaling in colonic smooth muscle of type 1 diabetic mice
Touw, Ketrija⋅Touw, Ketrija⋅Chakraborty, Saikat⋅Chakraborty, Saikat⋅Zhang, Wenwu⋅Zhang, Wenwu⋅Obukhov, Alexander⋅Obukhov, Alexander⋅Tune, Johnathan D⋅Tune, Johnathan⋅Gunst, Susan J⋅Gunst, Susan⋅Herring, B. P and Herring, B.
American Journal of Physiology, vol. 302, (no. 1), Jan 2012. | Journal Article
 
Inhibition of p21 activated kinase (PAK) reduces airway responsiveness in vivo and in vitro in murine and human airways.
Hoover, Wyn C⋅Hoover, Wyn C⋅Zhang, Wenwu⋅Zhang, Wenwu⋅Xue, Zhidong⋅Xue, Zhidong⋅Gao, Huanling⋅Gao, Huanling⋅Chernoff, Jonathan⋅Chernoff, Jonathan⋅Clapp, D Wade⋅Clapp, D W⋅Gunst, Susan J⋅Gunst, Susan J⋅Tepper, Robert S and Tepper, Robert S
PloS one, vol. 7, (no. 8), pp. e42601, 2012. | Journal Article
 
Last Word on Point: Alterations in airway smooth muscle phenotype do cause airway hyperresponsiveness in asthma
Gunst, Susan J and Panettieri, Jr, Reynold A
Journal of applied physiology (Bethesda, Md. : 1985), vol. 113, (no. 5), pp. 847, 2012-Sep-01. | Journal Article
 
Point: alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma.
Gunst, Susan J⋅Gunst, Susan J.⋅Panettieri, Reynold A and Panettieri, Reynold A.
Journal of applied physiology (Bethesda, Md. : 1985), vol. 113, (no. 5), pp. 837-9, 2012/Sep/1. | Journal Article
 
The small GTPase RhoA regulates the contraction of smooth muscle tissues by catalyzing the assembly of cytoskeletal signaling complexes at membrane adhesion sites.
Zhang, Wenwu⋅Zhang, Wenwu⋅Huang, Youliang⋅Huang, Youliang⋅Gunst, Susan J and Gunst, Susan J
The Journal of biological chemistry, vol. 287, (no. 41), pp. 33996-4008, 2012/Oct/5. | Journal Article
2011
Activation of vinculin induced by cholinergic stimulation regulates contraction of tracheal smooth muscle tissue.
Huang, Youliang⋅Zhang, Wenwu and Gunst, Susan J
The Journal of biological chemistry, vol. 286, (no. 5), pp. 3630-44, 2011/Feb/4. | Journal Article
 
Chronic continuous positive airway pressure (CPAP) reduces airway reactivity in vivo in an allergen-induced rabbit model of asthma.
Xue, Z⋅Yu, Y⋅Gao, H⋅Gunst, Susan J and Tepper, Robert S
Journal of applied physiology (Bethesda, Md. : 1985), vol. 111, (no. 2), pp. 353-7, 2011/Aug. | Journal Article
 
Mechanical stimuli and IL-13 interact at integrin adhesion complexes to regulate expression of smooth muscle myosin heavy chain in airway smooth muscle tissue
Desai, Leena P⋅Wu, Yidi⋅Tepper, Robert S and Gunst, Susan J
American Journal of Physiology, vol. 301, (no. 3), Sep 2011. | Journal Article
 
Physiology, reductionism, and translational medicine: the right mix.
Pitt, Bruce R⋅Christman, John W⋅Gunst, S J⋅Matthay, Michael A⋅Stevens, T and Ware, L B
American journal of physiology. Lung cellular and molecular physiology, vol. 301, (no. 4), pp. L389-90, 2011/Oct. | Journal Article
2010
The effects of the small GTPase RhoA on the muscarinic contraction of airway smooth muscle result from its role in regulating actin polymerization.
Zhang, Wenwu⋅Zhang, Wenwu⋅Du, Liping⋅Du, Liping⋅Gunst, Susan and Gunst, Susan J
American journal of physiology. Cell physiology, vol. 299, (no. 2), pp. C298-306, 2010/Aug. | Journal Article
2009
Role of protein kinase Calpha in regulation of [Ca2+](I) and force in human myometrium.
Fomin, Victor P⋅Kronbergs, Andris⋅Gunst, Susan J⋅Tang, Dale⋅Simirskii, Vladimir⋅Hoffman, Matthew and Duncan, Randall L
Reproductive sciences (Thousand Oaks, Calif.), vol. 16, (no. 1), pp. 71-9, 2009/Jan. | Journal Article