207 Publications (Page 1 of 9)
2023
Development of Scaffold-Free Three-Dimensional Cholangiocyte Organoids to Study the Progression of Primary Sclerosing Cholangitis.
Zhang, WenjunKyritsi, KonstantinaIsidan, AbdulkadirPark, YujinLi, PingCross-Najafi, Arthur ALopez, KevinKennedy, LindseySato, KeisakuGlaser, ShannonFrancis, HeatherAlpini, Gianfranco and Ekser, Burcin
The American journal of pathology, May 30, 2023. | Journal Article
 
Endothelin Receptor-A Inhibition Decreases Ductular Reaction, Liver Fibrosis and Angiogenesis in a Model of Cholangitis.
Owen, TravisCarpino, GuidoChen, LixianKundu, DebjyotiWills, PaytonEkser, BurcinOnori, PaoloGaudio, EugenioAlpini, GianfrancoFrancis, Heather and Kennedy, Lindsey
Cellular and molecular gastroenterology and hepatology, June 17, 2023. | Journal Article
 
Gallstone and Gallbladder Disease: Biliary Tract and Cholangiopathies.
Ceci, LudovicaHan, YuyanKrutsinger, KelseyBaiocchi, LeonardoWu, NanKundu, DebjyotiKyritsi, KonstantinaZhou, TianhaoGaudio, EugenioFrancis, HeatherAlpini, Gianfranco and Kennedy, Lindsey
Comprehensive Physiology, vol. 13, (no. 3), pp. 4909-4943, June 26, 2023. | Journal Article
 
Knockout of secretin ameliorates biliary and liver phenotypes during alcohol-induced hepatotoxicity.
Kyritsi, KonstantinaKyritsi, KonstantinaKyritsi, KonstantinaKyritsi, KonstantinaWu, NanWu, NanWu, NanWu, NanZhou, TianhaoZhou, TianhaoZhou, TianhaoZhou, TianhaoCarpino, GuidoCarpino, GuidoCarpino, GuidoCarpino, GuidoBaiocchi, LeonardoBaiocchi, LeonardoBaiocchi, LeonardoBaiocchi, LeonardoKennedy, LindseyKennedy, LindseyKennedy, LindseyKennedy, LindseyChen, LixianChen, LixianChen, LixianChen, LixianCeci, LudovicaCeci, LudovicaCeci, LudovicaCeci, LudovicaMeyer, Alison AnnMeyer, Alison AnnMeyer, Alison AnnMeyer, Alison AnnBarupala, NipuniBarupala, NipuniBarupala, NipuniBarupala, NipuniFranchitto, AntonioFranchitto, AntonioFranchitto, AntonioFranchitto, AntonioOnori, PaoloOnori, PaoloOnori, PaoloOnori, PaoloEkser, BurcinEkser, BurcinEkser, BurcinEkser, BurcinGaudio, EugenioGaudio, EugenioGaudio, EugenioGaudio, EugenioWu, ChaodongWu, ChaodongWu, ChaodongWu, ChaodongMarakovits, CorinnMarakovits, CorinnMarakovits, CorinnMarakovits, CorinnChakraborty, SanjuktaChakraborty, SanjuktaChakraborty, SanjuktaChakraborty, SanjuktaFrancis, HeatherFrancis, HeatherFrancis, HeatherFrancis, HeatherGlaser, ShannonGlaser, ShannonGlaser, ShannonGlaser, ShannonAlpini, GianfrancoAlpini, GianfrancoAlpini, Gianfranco and Alpini, Gianfranco
Cell & bioscience, vol. 13, (no. 1), pp. 5, January 9, 2023. | Journal Article
 
p16 INK4A drives nonalcoholic fatty liver disease phenotypes in high fat diet fed mice through biliary E2F1/FOXO1/IGF-1 signaling.
Kundu, DebjyotiKennedy, LindseyZhou, TianhaoEkser, BurcinMeadows, VikSybenga, AmeliaKyritsi, KonstantinaChen, LixianCeci, LudovicaWu, NanWu, ChaodongGlaser, ShannonCarpino, GuidoOnori, PaoloGaudio, EugenioAlpini, Gianfranco and Francis, Heather
Hepatology (Baltimore, Md.), February 20, 2023. | Journal Article
 
Preparation and Characterization of IL-22 mRNA-loaded Lipid Nanoparticles.
Alghoul, ZahraSung, JunsikWu, KenjiAlpini, GianfrancoGlaser, ShannonYang, Chunhua and Merlin, Didier
Bio-protocol, vol. 13, (no. 7), pp. e4647, April 5, 2023. | Journal Article
 
Prolonged administration of a secretin receptor antagonist inhibits biliary senescence and liver fibrosis in Mdr2 -/- mice.
Wu, NanWu, NanZhou, TianhaoZhou, TianhaoCarpino, GuidoCarpino, GuidoBaiocchi, LeonardoBaiocchi, LeonardoKyritsi, KonstantinaKyritsi, KonstantinaKennedy, LindseyKennedy, LindseyCeci, LudovicaCeci, LudovicaChen, LixianChen, LixianWu, ChaodongWu, ChaodongKundu, DebjyotiKundu, DebjyotiBarupala, NipuniBarupala, NipuniFranchitto, AntonioFranchitto, AntonioOnori, PaoloOnori, PaoloEkser, BurcinEkser, BurcinGaudio, EugenioGaudio, EugenioFrancis, HeatherFrancis, HeatherGlaser, ShannonGlaser, ShannonAlpini, Gianfranco and Alpini, Gianfranco
Hepatology (Baltimore, Md.), February 20, 2023. | Journal Article
2022
Cannabinoid Receptor 1 Antagonism Demonstrates High Therapeutic Potential for the Treatment of Primary Sclerosing Cholangitis.
Kennedy, Lindsey and Alpini, Gianfranco
February 4, 2022
 
Development and characterization of human primary cholangiocarcinoma cell lines.
Isidan, AbdulkadirYenigun, AliSoma, DaikiAksu, EricLopez, KevinPark, YujinCross-Najafi, ArthurLi, PingKundu, DebjyotiHouse, Michael GChakraborty, SanjuktaGlaser, ShannonKennedy, LindseyFrancis, HeatherZhang, WenjunAlpini, Gianfranco and Ekser, Burcin
The American journal of pathology, May 28, 2022. | Journal Article
 
FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2-/- Mouse Model of Primary Sclerosing Cholangitis.
O'Brien, AprilO'Brien, AprilO'Brien, AprilZhou, TianhaoZhou, TianhaoZhou, TianhaoWhite, ToriWhite, ToriWhite, ToriMedford, AbigailMedford, AbigailMedford, AbigailChen, LixianChen, LixianChen, LixianKyritsi, KonstantinaKyritsi, KonstantinaKyritsi, KonstantinaWu, NanWu, NanWu, NanChilds, JonathanChilds, JonathanChilds, JonathanStiles, DanaleighStiles, DanaleighStiles, DanaleighCeci, LudovicaCeci, LudovicaCeci, LudovicaChakraborty, SanjuktaChakraborty, SanjuktaChakraborty, SanjuktaEkser, BurcinEkser, BurcinEkser, BurcinBaiocchi, LeonardoBaiocchi, LeonardoBaiocchi, LeonardoCarpino, GuidoCarpino, GuidoCarpino, GuidoGaudio, EugenioGaudio, EugenioGaudio, EugenioWu, ChaodongWu, ChaodongWu, ChaodongKennedy, LindseyKennedy, LindseyKennedy, LindseyFrancis, HeatherFrancis, HeatherFrancis, HeatherAlpini, GianfrancoAlpini, GianfrancoAlpini, GianfrancoGlaser, ShannonGlaser, Shannon and Glaser, Shannon
Hepatology communications, March 10, 2022. | Journal Article
 
Hepatocyte Adenosine Kinase Promotes Excessive Fat Deposition and Liver Inflammation.
Li, HongguiLi, HongguiLi, HongguiLi, HongguiZheng, JuanZheng, JuanZheng, JuanZheng, JuanXu, QianXu, QianXu, QianXu, QianYang, YongjianYang, YongjianYang, YongjianYang, YongjianZhou, JingZhou, JingZhou, JingZhou, JingGuo, XinleiGuo, XinleiGuo, XinleiGuo, XinleiCai, YongfengCai, YongfengCai, YongfengCai, YongfengCai, James JCai, James JCai, James JCai, James JXie, LinglinXie, LinglinXie, LinglinXie, LinglinAwika, JosephAwika, JosephAwika, JosephAwika, JosephHan, XianlinHan, XianlinHan, XianlinHan, XianlinLi, QingshengLi, QingshengLi, QingshengLi, QingshengKennedy, LindseyKennedy, LindseyKennedy, LindseyKennedy, LindseyFrancis, HeatherFrancis, HeatherFrancis, HeatherFrancis, HeatherGlaser, ShannonGlaser, ShannonGlaser, ShannonGlaser, ShannonHuo, YuqingHuo, YuqingHuo, YuqingHuo, YuqingAlpini, GianfrancoAlpini, GianfrancoAlpini, GianfrancoAlpini, GianfrancoWu, ChaodongWu, ChaodongWu, Chaodong and Wu, Chaodong
Gastroenterology, September 28, 2022. | Journal Article
 
Indole Supplementation Ameliorates MCD-induced NASH in mice.
Zhu, BilianZhu, BilianZhu, BilianZhu, BilianLi, HongguiLi, HongguiLi, HongguiLi, HongguiLu, BangchaoLu, BangchaoLu, BangchaoLu, BangchaoGuo, XinleiGuo, XinleiGuo, XinleiGuo, XinleiWu, ChiashanWu, ChiashanWu, ChiashanWu, ChiashanWang, FenWang, FenWang, FenWang, FenLi, QingshengLi, QingshengLi, QingshengLi, QingshengXie, LinglinXie, LinglinXie, LinglinXie, LinglinGlaser, ShannonGlaser, ShannonGlaser, ShannonGlaser, ShannonFrancis, HeatherFrancis, HeatherFrancis, HeatherFrancis, HeatherAlpini, GianfrancoAlpini, GianfrancoAlpini, GianfrancoAlpini, GianfrancoWu, ChaodongWu, ChaodongWu, Chaodong and Wu, Chaodong
The Journal of nutritional biochemistry, pp. 109041, May 11, 2022. | Journal Article
 
Lipid nanoparticles for oral delivery of nucleic acids for treating inflammatory bowel disease.
Yang, ChunhuaAlpini, GianfrancoGlaser, Shannon and Merlin, Didier
November 1, 2022
 
Macrophage-Specific SCAP Promotes Liver and Adipose Tissue Damage in a Lean NAFLD Model: Lean, Mean, Proinflammatory Machine.
Kennedy, LindseyFrancis, Heather and Alpini, Gianfranco
April 29, 2022
 
Mast cells selectively target large cholangiocytes during biliary injury via H2HR-mediated cAMP/pERK1/2 signaling.
Zhou, TianhaoMeadows, VikKundu, DebjyotiKyritsi, KonstantinaOwen, TravisCeci, LudovicaCarpino, GuidoOnori, PaoloGaudio, EugenioWu, NanGlaser, ShannonEkser, BurcinAlpini, GianfrancoKennedy, Lindsey and Francis, Heather
Hepatology communications, July 7, 2022. | Journal Article
 
Molecular Mechanisms Linking Risk Factors to Cholangiocarcinoma Development
Ceci, LudovicaCeci, LudovicaCeci, LudovicaCeci, LudovicaZhou, TianhaoCeci, LudovicaCeci, LudovicaCeci, LudovicaZhou, TianhaoLenci, IlariaZhou, TianhaoZhou, TianhaoMeadows, VikZhou, TianhaoZhou, TianhaoZhou, TianhaoLenci, IlariaKennedy, LindseyLenci, IlariaLenci, IlariaMeadows, VikLi, PingMeadows, VikMeadows, VikKennedy, LindseyKennedy, LindseyEkser, BurcinKennedy, LindseyLi, PingLi, PingLi, PingMilana, MartinaEkser, BurcinEkser, BurcinEkser, BurcinZhang, WenjunWu, ChaodongMilana, MartinaMilana, MartinaMilana, MartinaZhang, WenjunSato, KeisakuZhang, WenjunZhang, WenjunChakraborty, SanjuktaWu, ChaodongWu, ChaodongWu, ChaodongGlaser, Shannon S.Sato, KeisakuSato, KeisakuSato, KeisakuChakraborty, SanjuktaFrancis, HeatherChakraborty, SanjuktaChakraborty, SanjuktaGlaser, Shannon SGlaser, Shannon SGlaser, Shannon SAlpini, GianfrancoFrancis, HeatherFrancis, HeatherBaiocchi, LeonardoFrancis, HeatherAlpini, GianfrancoAlpini, GianfrancoAlpini, GianfrancoAlpini, GianfrancoAlpini, GianfrancoAlpini, GianfrancoBaiocchi, LeonardoBaiocchi, LeonardoBaiocchi, LeonardoBaiocchi, LeonardoBaiocchi, Leonardo and Baiocchi, Leonardo
Cancers, vol. 14, (no. 6), 2022. | Journal Article
 
Organoid Technology: Are Human Cholangiocyte Organoids Immune Protected?
Ekser, BurcinEkser, BurcinZhang, WenjunZhang, WenjunLi, PingLi, PingFrancis, HeatherFrancis, HeatherAlpini, Gianfranco and Alpini, Gianfranco
Transplantation, vol. 106, (no. 4), pp. e249, April 1, 2022. | Journal Article
 
Pathophysiological Roles of Ductular Reaction in Liver Inflammation and Hepatic Fibrogenesis.
Sato, KeisakuPham, LinhGlaser, ShannonFrancis, Heather and Alpini, Gianfranco
Cellular and molecular gastroenterology and hepatology, November 23, 2022. | Journal Article
 
Prolonged administration of melatonin ameliorates liver phenotypes in cholestatic murine model.
Ceci, LudovicaChen, LixianBaiocchi, LeonardoWu, NanKennedy, LindseyCarpino, GuidoKyritsi, KonstantinaZhou, TianhaoOwen, TravisKundu, DebjyotiSybenga, AmeliaIsidan, AbdulkadirEkser, BurcinFranchitto, AntonioOnori, PaoloGaudio, EugenioMancinelli, RominaFrancis, HeatherAlpini, Gianfranco and Glaser, Shannon
Cellular and molecular gastroenterology and hepatology, July 18, 2022. | Journal Article
 
Role of ductular reaction and ductular-canalicular junctions in identifying severe primary biliary cholangitis.
Overi, DilettaCarpino, GuidoCristoferi, LauraOnori, PaoloKennedy, LindseyFrancis, HeatherZucchini, NicolaRigamonti, CristinaViganĂ², MauroFloreani, AnnarosaD'Amato, DaphneGerussi, AlessioVenere, RosannaAlpini, GianfrancoGlaser, ShannonAlvaro, DomenicoInvernizzi, PietroGaudio, EugenioCardinale, Vincenzo and Carbone, Marco
JHEP reports : innovation in hepatology, vol. 4, (no. 11), pp. 100556, November 2022. | Journal Article
 
Secretin alleviates biliary and liver injury during late-stage primary biliary cholangitis via restoration of secretory processes.
Kennedy, LindseyCarpino, GuidoOwen, TravisCeci, LudovicaKundu, DebjyotiMeadows, VikKyritsi, KonstantinaFranchitto, AntonioOnori, PaoloIsidan, AbdulkadirZhang, WenjunEkser, BurcinAlvaro, DomenicoGaudio, EugenioGershwin, M EricFrancis, HeatherGlaser, Shannon and Alpini, Gianfranco
Journal of hepatology, August 17, 2022. | Journal Article
 
The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling
Mancinelli, RominaMancinelli, RominaMancinelli, RominaMancinelli, RominaCeci, LudovicaCeci, LudovicaCeci, LudovicaCeci, LudovicaKennedy, LindseyKennedy, LindseyFrancis, HeatherFrancis, HeatherMeadows, VikMeadows, VikChen, LixianChen, LixianCarpino, GuidoCarpino, GuidoKyritsi, KonstantinaKyritsi, KonstantinaWu, NanWu, NanZhou, TianhaoZhou, TianhaoSato, KeisakuSato, KeisakuPannarale, LuigiPannarale, LuigiGlaser, ShannonGlaser, ShannonChakraborty, SanjuktaChakraborty, SanjuktaAlpini, GianfrancoAlpini, GianfrancoGaudio, EugenioGaudio, EugenioOnori, PaoloOnori, PaoloFranchitto, AntonioFranchitto, AntonioFranchitto, Antonio and Franchitto, Antonio
Cells, vol. 11, (no. 9), 2022. | Journal Article
 
The functional roles of immune cells in primary liver cancer.
Pham, LinhPham, LinhKyritsi, KonstantinaKyritsi, KonstantinaZhou, TianhaoZhou, TianhaoCeci, LudovicaCeci, LudovicaBaiocchi, LeonardoBaiocchi, LeonardoKennedy, LindseyKennedy, LindseyChakraborty, SanjuktaChakraborty, SanjuktaGlaser, ShannonGlaser, ShannonFrancis, HeatherFrancis, HeatherAlpini, GianfrancoAlpini, GianfrancoSato, Keisaku and Sato, Keisaku
The American journal of pathology, March 22, 2022. | Journal Article
 
Therapeutic Use of Viruses: Newcastle Disease Virus HK84 Oncolytic Treatment for Hepatocellular Carcinoma.
Baiocchi, LeonardoFrancis, Heather and Alpini, Gianfranco
Journal of clinical and translational hepatology, vol. 10, (no. 5), pp. 783-785, October 28, 2022. | Journal Article
 
What the duct: Imaging ductular reaction spanning the fibrotic areas in primary sclerosing cholangitis (PSC).
Owen, TravisFrancis, HeatherAlpini, Gianfranco and Kennedy, Lindsey
(pp. 166392). March 18, 2022