25 Publications
2023
Obesity induced inflammation exacerbates clonal hematopoiesis.
Pasupuleti, Santhosh Kumar⋅Pasupuleti, Santhosh Kumar⋅Pasupuleti, Santhosh Kumar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Burns, Sarah S⋅Burns, Sarah S⋅Burns, Sarah S⋅Palam, Lakshmi Reddy⋅Palam, Lakshmi Reddy⋅Palam, Lakshmi Reddy⋅Kanumuri, Rahul⋅Kanumuri, Rahul⋅Kanumuri, Rahul⋅Kumar, Ramesh⋅Kumar, Ramesh⋅Kumar, Ramesh⋅Pandhiri, Taruni R⋅Pandhiri, Taruni R⋅Pandhiri, Taruni R⋅Dave, Utpal⋅Dave, Utpal⋅Dave, Utpal⋅Yellapu, Nanda Kumar⋅Yellapu, Nanda Kumar⋅Yellapu, Nanda Kumar⋅Zhou, Xinyu⋅Zhou, Xinyu⋅Zhou, Xinyu⋅Zhang, Chi⋅Zhang, Chi⋅Zhang, Chi⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Yu, Zhi⋅Yu, Zhi⋅Yu, Zhi⋅Honigberg, Michael C⋅Honigberg, Michael C⋅Honigberg, Michael C⋅Bick, Alexander G⋅Bick, Alexander G⋅Bick, Alexander G⋅Griffin, Gabriel K⋅Griffin, Gabriel K⋅Griffin, Gabriel K⋅Niroula, Abhishek⋅Niroula, Abhishek⋅Niroula, Abhishek⋅Ebert, Benjamin L⋅Ebert, Benjamin L⋅Ebert, Benjamin L⋅Paczesny, Sophie⋅Paczesny, Sophie⋅Paczesny, Sophie⋅Natarajan, Pradeep⋅Natarajan, Pradeep⋅Natarajan, Pradeep⋅Kapur, Reuben⋅Kapur, Reuben and Kapur, Reuben
The Journal of clinical investigation, April 18, 2023. | Journal Article
 
Obesity-induced inflammation exacerbates clonal hematopoiesis
Pasupuleti, Santhosh K⋅Pasupuleti, Santhosh K⋅Pasupuleti, Santhosh K⋅Pasupuleti, Santhosh K⋅Pasupuleti, Santhosh K⋅Pasupuleti, Santhosh K⋅Pasupuleti, Santhosh K⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Burns, Sarah S⋅Burns, Sarah S⋅Burns, Sarah S⋅Burns, Sarah S⋅Burns, Sarah S⋅Burns, Sarah S⋅Burns, Sarah S⋅Palam, Lakshmi R⋅Palam, Lakshmi R⋅Palam, Lakshmi R⋅Palam, Lakshmi R⋅Palam, Lakshmi R⋅Palam, Lakshmi R⋅Palam, Lakshmi R⋅Kanumuri, Rahul⋅Kanumuri, Rahul⋅Kanumuri, Rahul⋅Kanumuri, Rahul⋅Kanumuri, Rahul⋅Kanumuri, Rahul⋅Kanumuri, Rahul⋅Kumar, Ramesh⋅Kumar, Ramesh⋅Kumar, Ramesh⋅Kumar, Ramesh⋅Kumar, Ramesh⋅Kumar, Ramesh⋅Kumar, Ramesh⋅Pandhiri, Taruni R⋅Pandhiri, Taruni R⋅Pandhiri, Taruni R⋅Pandhiri, Taruni R⋅Pandhiri, Taruni R⋅Pandhiri, Taruni R⋅Pandhiri, Taruni R⋅Dave, Utpal P⋅Dave, Utpal P⋅Dave, Utpal P⋅Dave, Utpal P⋅Dave, Utpal P⋅Dave, Utpal P⋅Dave, Utpal P⋅Yellapu, Nanda K⋅Yellapu, Nanda K⋅Yellapu, Nanda K⋅Yellapu, Nanda K⋅Yellapu, Nanda K⋅Yellapu, Nanda K⋅Yellapu, Nanda K⋅Zhou, Xinyu⋅Zhou, Xinyu⋅Zhou, Xinyu⋅Zhou, Xinyu⋅Zhou, Xinyu⋅Zhou, Xinyu⋅Zhou, Xinyu⋅Zhang, Chi⋅Zhang, Chi⋅Zhang, Chi⋅Zhang, Chi⋅Zhang, Chi⋅Zhang, Chi⋅Zhang, Chi⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Yu, Zhi⋅Yu, Zhi⋅Yu, Zhi⋅Yu, Zhi⋅Yu, Zhi⋅Yu, Zhi⋅Yu, Zhi⋅Honigberg, Michael C⋅Honigberg, Michael C⋅Honigberg, Michael C⋅Honigberg, Michael C⋅Honigberg, Michael C⋅Honigberg, Michael C⋅Honigberg, Michael C⋅Bick, Alexander G⋅Bick, Alexander G⋅Bick, Alexander G⋅Bick, Alexander G⋅Bick, Alexander G⋅Bick, Alexander G⋅Bick, Alexander G⋅Griffin, Gabriel K⋅Griffin, Gabriel K⋅Griffin, Gabriel K⋅Griffin, Gabriel K⋅Griffin, Gabriel K⋅Griffin, Gabriel K⋅Griffin, Gabriel K⋅Niroula, Abhishek⋅Niroula, Abhishek⋅Niroula, Abhishek⋅Niroula, Abhishek⋅Niroula, Abhishek⋅Niroula, Abhishek⋅Niroula, Abhishek⋅Ebert, Benjamin L⋅Ebert, Benjamin L⋅Ebert, Benjamin L⋅Ebert, Benjamin L⋅Ebert, Benjamin L⋅Ebert, Benjamin L⋅Ebert, Benjamin L⋅Paczesny, Sophie⋅Paczesny, Sophie⋅Paczesny, Sophie⋅Paczesny, Sophie⋅Paczesny, Sophie⋅Paczesny, Sophie⋅Paczesny, Sophie⋅Natarajan, Pradeep⋅Natarajan, Pradeep⋅Natarajan, Pradeep⋅Natarajan, Pradeep⋅Natarajan, Pradeep⋅Natarajan, Pradeep⋅Natarajan, Pradeep⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben and Kapur, Reuben
Journal of Clinical Investigation, vol. 133, (no. 11), pp. 1-21, Jun 2023. | Journal Article
2021
Extranodal NK/T-cell lymphoma primarily presenting as two adjacent slowly growing skin nodules with prominent epidermotropism and CD30 expression, a case report and review of literature
Mohammed, Arooj⋅Dave, Utpal⋅MS, Sahand R and Alomari, Ahmed K
2021
 
Extranodal NK/T-cell lymphoma primarily presenting as two adjacent slowly growing skin nodules with prominent epidermotropism and CD30 expression, a case report and review of literature.
Mohammed, Arooj⋅Dave, Utpal⋅Ms, Sahand Rahnama-Moghadam and Alomari, Ahmed K
Dermatology online journal, vol. 27, (no. 12), December 15, 2021. | Journal Article
2020
Ldb1 is required for Lmo2 oncogene-induced thymocyte self-renewal and T-cell Acute Lymphoblastic Leukemia
Li, LiQi⋅Mitra, Apratim⋅Cui, Kairong⋅Zhao, Bin⋅Choi, Seeyoung⋅Lee, Jan⋅Stamos, Daniel Beau⋅El-Khoury, Dalal⋅Warzecha, Claude⋅Pfeifer, Karl⋅Hardwick, Joyce⋅Zhao, Keji⋅Venters, Bryan⋅Dave, Utpal P and Love, Paul E
Blood, 2020-Mar-16. | Journal Article
2019
LIM Domain Protein 1 (Ldb1) Is Required for Lmo2 Oncogene-Induced Thymocyte Self-Renewal and T-Cell Leukemia in a Mouse Model of Human T-ALL
Li, Liqi⋅Mitra, Apratim⋅Zhao, Bin⋅Choi, Seeyoung⋅Lee, Jan⋅Stamos, Daniel⋅Warzecha, Claude⋅Pfeifer, Karl⋅Hardwick, Joyce⋅Venters, Bryan⋅Love, Paul and Dave, Utpal
Blood, vol. 134, (no. Supplement_1), pp. 2538, 2019-11-13. | Journal Article
2018
Comprehensive Genomic Profiling of Angioimmunoblastic T-Cell Lymphoma (AITL) in Chinese Patients
Zhong, Lihua⋅Wang, Jianchao⋅Chen, Yanping⋅Lin, Weiqing⋅Liu, Xiaoyan⋅Dou, Ying⋅Sun, Lihua⋅Zhao, Songhui⋅Dong, Xiaowei⋅Dave, Utpal⋅Wang, Kai and Chen, Gang
Blood, vol. 132, (no. Supplement 1), pp. 5293, 2018-11-29. | Journal Article
2015
A case study for cloud based high throughput analysis of NGS data using the globus genomics system
Bhuvaneshwar, Krithika⋅Bhuvaneshwar, Krithika⋅Sulakhe, Dinanath⋅Sulakhe, Dinanath⋅Gauba, Robinder⋅Gauba, Robinder⋅Rodriguez, Alex⋅Rodriguez, Alex⋅Madduri, Ravi⋅Madduri, Ravi⋅Dave, Utpal⋅Dave, Utpal⋅Lacinski, Lukasz⋅Lacinski, Lukasz⋅Foster, Ian⋅Foster, Ian⋅Gusev, Yuriy⋅Gusev, Yuriy⋅Madhavan, Subha and Madhavan, Subha
Computational and structural biotechnology journal, vol. 13, (no. C), pp. 74, 2015-00-00. | Journal Article
 
Lmo2's Oncogenic Function in T-Cell Leukemia Requires Ldb1
Li, Liqi⋅Layer, Justin H⋅Warzecha, Claude⋅Tripathi, Rati⋅Love, Paul and Dave, Utpal P
Blood, vol. 126, (no. 23), pp. 3663, 2015-12-03. | Journal Article
 
Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides
McGirt, Laura Y⋅McGirt, Laura Y⋅Jia, Peilin⋅Jia, Peilin⋅Baerenwald, Devin A⋅Baerenwald, Devin A⋅Duszynski, Robert J⋅Duszynski, Robert J⋅Dahlman, Kimberly B⋅Dahlman, Kimberly B⋅Zic, John A⋅Zic, John A⋅Zwerner, Jeffrey P⋅Zwerner, Jeffrey P⋅Hucks, Donald⋅Hucks, Donald⋅Dave, Utpal⋅Dave, Utpal⋅Zhao, Zhongming⋅Zhao, Zhongming⋅Eischen, Christine M and Eischen, Christine M
Blood, vol. 126, (no. 4), pp. 519, 2015-Jul-23. | Journal Article
2014
Comprehensive Hybrid Capture-Based Genomic Profiling of T-Cell Leukemias and Lymphomas Reveals Targetable JAK1 and JAK3 Co-Existing Mutations
Dave, Utpal P⋅Palma, Norma⋅Wang, Kai⋅Reddy, Nishitha M⋅Ali, Siraj⋅Tripathi, Rati⋅Greenplate, Allison⋅Irish, Jonathan Michael⋅Unutmaz, Derya⋅Stephens, Phil J and Miller, Vincent A
Blood, vol. 124, (no. 21), pp. 1672, 2014-12-06. | Journal Article
 
Experiences building Globus Genomics: a next‐generation sequencing analysis service using Galaxy, Globus, and Amazon Web Services
Madduri, Ravi K⋅Madduri, Ravi⋅Madduri, Ravi⋅Madduri, Ravi K⋅Sulakhe, Dinanath⋅Sulakhe, Dinanath⋅Sulakhe, Dinanath⋅Sulakhe, Dinanath⋅Lacinski, Lukasz⋅Lacinski, Lukasz⋅Lacinski, Lukasz⋅Lacinski, Lukasz⋅Liu, Bo⋅Liu, Bo⋅Liu, Bo⋅Liu, Bo⋅Rodriguez, Alex⋅Rodriguez, Alex⋅Rodriguez, Alex⋅Rodriguez, Alex⋅Chard, Kyle⋅Chard, Kyle⋅Chard, Kyle⋅Chard, Kyle⋅Dave, Utpal⋅Dave, Utpal J⋅Dave, Utpal⋅Dave, Utpal J⋅Foster, Ian T⋅Foster, Ian T⋅Foster, Ian and Foster, Ian
Concurrency and Computation: Practice and Experience, vol. 26, (no. 13), pp. 2279, 10 September 2014. | Journal Article
2013
Hhex Is a Critical Gene In The Development Of Normal and Malignant Lymphoid Cells
Goodings, Charnise⋅Smith, Stephen B⋅Mathias, Elizabeth⋅Smith, Elizabeth⋅Tripathi, Rati⋅Elliott, Natalina E⋅Cleveland, Susan⋅Dave, Utpal P and Du, Yang
Blood, vol. 122, (no. 21), pp. 3788, 2013-11-15. | Journal Article
2012
Therapeutic Utility of PI3Kγ Inhibition in Leukemogenesis and Tumor Cell Survival
Diacovo, Thomas⋅Whye, Dosh⋅Efimenko, Evgeni⋅Chen, Jianchung⋅Tosello, Valeria⋅De Keersmaecker, Kim⋅Kashishian, Adam⋅Thompson, Mary Ann⋅Castillo, Mireia⋅Cordon-Cardo, Carlos⋅Dave, Utpal P⋅Ferrando, Adolfo A⋅Lannutti, Brian J and Subramaniam, Prem
Blood, vol. 120, (no. 21), pp. 1492, 2012-11-16. | Journal Article
2011
Abstract 4977: Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables discovery of a novel C6orf204-PDGFRβ fusion in a patient with T-ALL and eosinophilia
Chmielecki, Juliann⋅Peifer, Martin⋅Viale, Agnes⋅Hutchinson, Kathernie⋅Giltnane, Jennifer⋅Socci, Nicholas D⋅Yenamandra, Ashwini⋅Jagasia, Madan⋅Kim, Annette S⋅Dave, Utpal⋅Thomas, Roman K and Pao, William
Cancer Research, vol. 71, (no. 8 Supplement), pp. 4977, 2011-04-15. | Journal Article
 
Cooperating Oncogenes and Their Targets in LMO2-Induced T-Cell Leukemia
Smith, Stephen B⋅Tripathi, Rati⋅Cleveland, Susan⋅Mathias, Elizabeth⋅Yi, Andrew⋅Mullighan, Charles G⋅Downing, James R⋅Copeland, Neal G⋅Jenkins, Nancy A and Dave, Utpal P
Blood, vol. 118, (no. 21), pp. 2458, 2011-11-18. | Journal Article
 
Enforced E47 Expression Has Differential Effects on Lmo2-Induced T-Cell Leukemia
Goodings, Charnise and Dave, Utpal P
Blood, vol. 118, (no. 21), pp. 4637, 2011-11-18. | Journal Article
2010
A role for proapoptotic Bax and Bak in T-cell differentiation and transformation
Biswas, Subhrajit⋅Biswas, Subhrajit⋅Shi, Qiong⋅Shi, Qiong⋅Matise, Lauren⋅Matise, Lauren⋅Cleveland, Susan⋅Cleveland, Susan⋅Dave, Utpal⋅Dave, Utpal⋅Zinkel, Sandra and Zinkel, Sandra S
Blood, vol. 116, (no. 24), pp. 5246, 2010-Dec-09. | Journal Article
2009
Sox4 Downregulates Pu.1 Gene Expression by Binding to An Upper Regulatory Element of Pu.1, a Mechanism Contributing to Leukemogenesis
Aue, Georg⋅Du, Yang⋅Cleveland, Susan⋅Smith, Stephen⋅Dave, Utpal P⋅Jenkins, Nancy⋅Copeland, Neal G and Dunbar, Cynthia
Blood, vol. 114, (no. 22), pp. 3979, 2009-11-20. | Journal Article
 
The Role of JAK3 mutations in Adult T-Cell Leukemia/Lymphoma
Elliott, Natalina E⋅Cleveland, Susan⋅Grann, Victor⋅Janik, John E and Dave, Utpal P
Blood, vol. 114, (no. 22), pp. 1940, 2009-11-20. | Journal Article
2008
Lmo2 Induces T-Cell Leukemia with Epigenetic Deregulation of CD4
Cleveland, Susan and Dave, Utpal P
Blood, vol. 112, (no. 11), pp. 3361, 2008-11-16. | Journal Article
 
Murine Leukemias with Insertional Mutations at Lmo2 Are Highly Predicitive of Leukemias Induced Following Gene Therapy in SCID-X1 Patients
Dave, Utpal P⋅Akagi, Keiko⋅Tripathi, Rati⋅Cleveland, Susan⋅Thompson, Mary⋅Yi, Ming⋅Stephens, Robert⋅Downing, James R⋅Jenkins, Nancy and Copeland, Neal G
Blood, vol. 112, (no. 11), pp. 4629, 2008-11-16. | Journal Article
2007
Insertional Activation of GLI2 in Adult T-Cell Leukemia/Lymphoma
Cleveland, Susan M and Dave, Utpal P
Blood, vol. 110, (no. 11), pp. 4149, 2007-11-16. | Journal Article
2004
Proviral Tagging Combined with Human Microarray Data Reveals Genes and Pathways That Cooperate in Disease Induction
Dave, Utpal P⋅Akagi, Keiko⋅Dupuy, Adam⋅Suzuki, Takeshi⋅Jenkins, Nancy A and Copeland, Neal G
Blood, vol. 104, (no. 11), pp. 3492, 2004-11-16. | Journal Article
2000
Asparagine-Proline Sequence within Membrane-Spanning Segment of SREBP Triggers Intramembrane Cleavage by Site-2 Protease
Ye, Jin⋅Ye, Jin⋅Dave, Utpal⋅Dave, Utpal⋅Grishin, Nick⋅Grishin, Nick V⋅Goldstein, Joseph L⋅Goldstein, Joseph⋅Brown, Michael and Brown, Michael S
Proceedings of the National Academy of Sciences of the United States of America, vol. 97, (no. 10), pp. 5128, 20000509. | Journal Article