76 Publications (Page 1 of 4)
2014
LLY-2707, a novel nonsteroidal glucocorticoid antagonist that reduces atypical antipsychotic-associated weight gain in rats.
Sindelar, Dana K⋅Carson, Mathew W⋅Morin, Michelle⋅Shaw, Janice⋅Barr, Robert J⋅Need, Anne⋅Alexander-Chacko, Jesline⋅Coghlan, Michael and Gehlert, Donald R
The Journal of pharmacology and experimental therapeutics, vol. 348, (no. 1), pp. 192-201, 2014/Jan. | Journal Article
2012
Effects of corticotropin-releasing factor 1 receptor antagonism on the hypothalamic-pituitary-adrenal axis of rodents.
Gehlert, Donald R⋅Cramer, Jeffrey and Morin, S M
The Journal of pharmacology and experimental therapeutics, vol. 341, (no. 3), pp. 672-80, 2012/Jun. | Journal Article
 
Melanin-concentrating hormone receptor 1 (MCH1-R) antagonism: reduced appetite for calories and suppression of addictive-like behaviors.
Karlsson, Camilla⋅Zook, Michelle⋅Ciccocioppo, Roberto⋅Gehlert, Donald R⋅Thorsell, Annika⋅Heilig, Markus and Cippitelli, Andrea
Pharmacology, biochemistry, and behavior, vol. 102, (no. 3), pp. 400-6, 2012/Sep. | Journal Article
2011
In vitro and ex vivo autoradiography of the NK-1 antagonist [³H]-LY686017 in Guinea pig brain.
Gackenheimer, Susan L and Gehlert, Donald R
Neuropeptides, vol. 45, (no. 2), pp. 157-64, 2011/Apr. | Journal Article
 
In vitro and ex vivo autoradiography of the NK-1 antagonist [[super]3H]-LY686017 in Guinea pig brain
Gackenheimer, Susan L and Gehlert, Donald R
Neuropeptides, vol. 45, (no. 2), pp. 157-164, 2011. | Journal Article
2010
Development of the 2nd generation neurokinin-1 receptor antagonist LY686017 for social anxiety disorder
Tauscher, Johannes⋅Kielbasa, William⋅Iyengar, Smriti⋅Vandenhende, Francois⋅Peng, Xiaomei⋅Mozley, David⋅Gehlert, Donald R and Marek, Gerard
European Neuropsychopharmacology, vol. 20, (no. 2), pp. 80-87, 2010. | Journal Article
 
Suppression of alcohol self-administration and reinstatement of alcohol seeking by melanin-concentrating hormone receptor 1 (MCH1-R) antagonism in Wistar rats
Cippitelli, Andrea⋅Karlsson, Camilla⋅Shaw, Janice L⋅Thorsell, Annika⋅Gehlert, Donald R and Heilig, Markus
Psychopharmacology, vol. 211, (no. 4), pp. 367-375, 2010. | Journal Article
2009
Preclinical evaluation of melanin-concentrating hormone receptor 1 antagonism for the treatment of obesity and depression.
Gehlert, Donald R⋅Rasmussen, Kurt⋅Shaw, Janice⋅Li, Xia⋅Ardayfio, Paul⋅Craft, Libbey⋅Coskun, Tamer⋅Zhang, Hong Y⋅Chen, Yanyun and Witkin, Jeffrey M
The Journal of pharmacology and experimental therapeutics, vol. 329, (no. 2), pp. 429-38, 2009/May. | Journal Article
 
Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond.
Ciccocioppo, Roberto⋅Ciccocioppo, Roberto⋅Gehlert, Donald R.⋅Gehlert, Donald R⋅Ryabinin, Andrey⋅Ryabinin, Andrey⋅Kaur, Simranjit⋅Kaur, Simranjit⋅Cippitelli, Andrea⋅Cippitelli, Andrea⋅Thorsell, Annika⋅Thorsell, Annika⋅Lê, Anh D⋅Lê, Anh D.⋅Hipskind, Philip A⋅Hipskind, Philip A.⋅Hamdouchi, Chafiq⋅Hamdouchi, Chafiq⋅Lu, Jianliang⋅Lu, Jianliang⋅Hembre, Erik J⋅Hembre, Erik J.⋅Cramer, Jeffrey⋅Cramer, Jeffrey⋅Song, Min⋅Song, Min⋅Mc Kinzie, David L⋅McKinzie, David⋅Morin, Michelle⋅Morin, Michelle⋅Economidou, Daina⋅Economidou, Daina⋅Stopponi, Serena⋅Stopponi, Serena⋅Cannella, Nazzareno⋅Cannella, Nazzareno⋅Braconi, Simone⋅Braconi, Simone⋅Kallupi, Marsida⋅Kallupi, Marsida⋅de Guglielmo, Giordano⋅de Guglielmo, Giordano⋅Massi, Maurizio⋅Massi, Maurizio⋅George, David T⋅George, David T.⋅Gilman, Jody⋅Gilman, Jody⋅Hersh, Jacqueline R⋅Hersh, Jacqueline⋅Tauscher, Johannes T.⋅Tauscher, Johannes T⋅Hunt, Stephen P⋅Hunt, Stephen P.⋅Hommer, Daniel⋅Hommer, Daniel⋅Heilig, Markus and Heilig, Markus
Alcohol (Fayetteville, N.Y.), vol. 43, (no. 7), pp. 491-8, 2009/Nov. | Journal Article
2008
Behavioral and biochemical responses to d-amphetamine in MCH1 receptor knockout mice
Smith, Daniel G⋅Qi, Hongshi⋅Svenningsson, Per⋅Wade, Mark⋅Davis, Richard J⋅Gehlert, Donald R and Nomikos, George G
Synapse, vol. 62, (no. 2), pp. 128-136, 2008. | Journal Article
 
Monoaminergic compensation in the neuropeptide Y deficient mouse brain
Gehlert, Donald R⋅Thompson, LK⋅Hemrick-Luecke, SK and Shaw, J.
Neuropeptides, vol. 42, (no. 3), pp. 367-375, 2008. | Journal Article
 
Neurokinin 1 Receptor Antagonism as a Possible Therapy for Alcoholism
George, David T⋅Gilman, Jodi⋅Hersh, Jacqueline R⋅Thorsell, Annika⋅Herion, David⋅Geyer, Christopher⋅Peng, Xiaomei⋅Kielbasa, William⋅Rawlings, Robert⋅Brandt, John E⋅Gehlert, Donald R⋅Tauscher, Johannes T⋅Hunt, Stephen P⋅Hommer, Daniel and Heilig, Markus
Science, vol. 319, (no. 5869), pp. 1536-1539, Mar 14, 2008. | Journal Article
 
Neuropeptide Y in the Amygdala Induces Long-Term Resilience to Stress-Induced Reductions in Social Responses But Not Hypothalamic-Adrenal-Pituitary Axis Activity or Hyperthermia
Sajdyk, Tammy⋅Sajdyk, Tammy J⋅Johnson, Philip L⋅Johnson, Philip⋅Leitermann, Randy J⋅Leitermann, Randy⋅Fitz, Stephanie⋅Fitz, Stephanie D⋅Dietrich, Amy⋅Dietrich, Amy⋅Morin, Michelle⋅Morin, Michelle⋅Gehlert, Donald R⋅Gehlert, Donald⋅Urban, Janice H⋅Urban, Janice⋅Shekhar, Anantha and Shekhar, Anantha
Journal of Neuroscience, vol. 28, (no. 4), pp. 893-903, 2008. | Journal Article
2007
3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism.
Gehlert, Donald R⋅Cippitelli, Andrea⋅Thorsell, Annika⋅Lê, Anh D⋅Hipskind, Philip A⋅Hamdouchi, Chafiq⋅Lu, Jianliang⋅Hembre, Erik J⋅Cramer, Jeffrey⋅Song, Min⋅McKinzie, David⋅Morin, Michelle⋅Ciccocioppo, Roberto and Heilig, Markus
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 27, (no. 10), pp. 2718-26, 2007/Mar/7. | Journal Article
 
3-(4-Chloro-2-Morpholin-4-yl-Thiazol-5-yl)-8-(1-Ethylpropyl)-2,6-D imet hyl-Imidazo[1,2-b]Pyridazine: A Novel Brain-Penetrant, Orally Available Corticotropin-Releasing Factor Receptor 1 Antagonist with Efficacy in Animal Models of Alcoholism
Gehlert, Donald R⋅Cippitelli, Andrea⋅Thorsell, Annika⋅Le, Anh D⋅Hipskind, Philip A⋅Hamdouchi, Chafiq⋅Lu, Jianliang⋅Hembre, Erik J⋅Cramer, Jeffrey⋅Song, Min⋅McKinzie, David⋅Morin, Michelle⋅Ciccocioppo, Roberto and Heilig, Markus
Journal of Neuroscience, vol. 27, (no. 10), pp. 2718-2726, 2007. | Journal Article
 
Co-expression of neuropeptide Y Y1 and Y5 receptors results in heterodimerization and altered functional properties
Gehlert, Donald R⋅Schober, Douglas A⋅Morin, Michelle and Berglund, Magnus M
Biochemical Pharmacology, vol. 74, (no. 11), pp. 1652-1664, 2007. | Journal Article
 
Increased brain neuropeptide Y1 and Y2 receptor binding in NPY knock out mice does not result in increased receptor function.
Gehlert, Donald R and Shaw, Janice L
Peptides, vol. 28, (no. 2), pp. 241-9, 2007/Feb. | Journal Article
2006
Angiotensin-II Is a Putative Neurotransmitter in Lactate-Induced Panic-Like Responses in Rats with Disruption of GABAergic Inhibition in the Dorsomedial Hypothalamus
Shekhar, Anantha⋅Shekhar, Anantha⋅Johnson, Philip⋅Johnson, Philip L⋅Sajdyk, Tammy⋅Sajdyk, Tammy J⋅Fitz, Stephanie⋅Fitz, Stephanie D⋅Keim, Stanley R⋅Keim, Stanley⋅Kelley, Pamela E⋅Kelley, Pamela⋅Gehlert, Donald R⋅Gehlert, Donald⋅Di Micco, Joseph A and DiMicco, Joseph
Journal of Neuroscience, vol. 26, (no. 36), pp. 9205-9215, 2006. | Journal Article
 
Distribution of nociceptin and Ro64-6198 activated [35S]-GTPgammaS binding in the rat brain.
Gehlert, Donald R⋅Gackenheimer, Susan L and Shaw, Janice L
Neuropeptides, vol. 40, (no. 2), pp. 95-105, 2006/Apr. | Journal Article
 
Distribution of nociceptin and Ro64-6198 activated [ super(35)S]-GTP gamma S binding in the rat brain
Gehlert, Donald R⋅Gackenheimer, SL and Shaw, JL
Neuropeptides, vol. 40, (no. 2), pp. 95-105, 2006. | Journal Article
 
Distribution of NPY Y5-like immunoreactivity in the rat brain
Morin, S and Gehlert, Donald
Journal of Molecular Neuroscience, vol. 29, (no. 2), pp. 109-14, Jun 2006. | Journal Article
 
Exposure to predator odor stress increases efflux of frontal cortex acetylcholine and monoamines in mice: Comparisons with immobilization stress and reversal by chlordiazepoxide
Smith, DG⋅Davis, RJ⋅Gehlert, Donald R and Nomikos, GG
Brain Research, vol. 1114, (no. 1), pp. 24-30, 2006. | Journal Article
 
Melanin-Concentrating Hormone-1 Receptor Modulates Neuroendocrine, Behavioral, and Corticolimbic Neurochemical Stress Responses in Mice
Smith, Daniel G⋅Davis, Richard J⋅Rorick-Kehn, Linda⋅Morin, Michelle⋅Witkin, Jeffrey M⋅Mc Kinzie, David L⋅Nomikos, George G and Gehlert, Donald R
Neuropsychopharmacology, vol. 31, (no. 6), pp. 1135-45, Jun 2006. | Journal Article
2005
Mesolimbic Dopamine Super-Sensitivity in Melanin-Concentrating Hormone-1 Receptor-Deficient Mice
Smith, Daniel G⋅Tzavara, Eleni T⋅Shaw, Janice⋅Luecke, Susan⋅Wade, Mark⋅Davis, Richard⋅Salhoff, Craig⋅Nomikos, George G and Gehlert, Donald R
Journal of Neuroscience, vol. 25, (no. 4), pp. 914-922, 2005. | Journal Article
 
Stress and central Urocortin increase anxiety-like behavior in the social interaction test via the CRF1 receptor.
Gehlert, Donald R⋅Shekhar, Anantha⋅Morin, S M⋅Hipskind, Phillip A⋅Zink, Charity⋅Gackenheimer, Susan L⋅Shaw, Janice⋅Fitz, Stephanie D and Sajdyk, Tammy J
European journal of pharmacology, vol. 509, (no. 2-3), pp. 145-53, 2005/Feb/21. | Journal Article