148 Publications (Page 1 of 6)
2023
Abstract 2756: Custom G4 DNA microarray can determine large-scale binding selectivity of small molecules and proteins to oncogene G-quadruplexes
Wu, GuanhuiChen, LuyingHuseman, KristenTillo, DesireeRay, SreejanaChang, Ta-ChauSchneekloth, John S.Vinson, Charles and Yang, Danzhou
Cancer research (Chicago, Ill.), vol. 83, (no. 7_Supplement), pp. 2756, 2023-04-04. | Journal Article
 
Abstract 3103: Dual targeting MYC G-quadruplex and topoisomerase I by indenoisoquinolines for cancer therapy
Yang, DanzhouCushman, MarkWang, Kai-BoElsayed, Mohamed S.Wu, GuanhuiBuric, Adam J. and DeMoss, Mercedes
Cancer research (Chicago, Ill.), vol. 83, (no. 7_Supplement), pp. 3103, 2023-04-04. | Journal Article
 
Abstract 3840: High-resolution structural insights into targeting the MYC oncogene G-quadruplex with the quinoline derivative PEQ
Dickerhoff, JonathanDai, Jixun and Yang, Danzhou
Cancer research (Chicago, Ill.), vol. 83, (no. 7_Supplement), pp. 3840, 2023-04-04. | Journal Article
 
Abstract 3842: Berberine recognition of the dGMP-bound PDGFR-β promoter G-quadruplex: Structural insight into specific drug targeting
Wang, Kai-BoDickerhoff, JonathanHan, Yichen and Yang, Danzhou
Cancer research (Chicago, Ill.), vol. 83, (no. 7_Supplement), pp. 3842, 2023-04-04. | Journal Article
 
Abstract 3948: DDX5 helicase resolves G-quadruplex and transactivates MYC expression
Wu, GuanhuiWu, GuanhuiXing, ZhengXing, ZhengChen, LuyingChen, LuyingTran, Elizabeth J.Tran, Elizabeth J.Yang, Danzhou and Yang, Danzhou
Cancer research (Chicago, Ill.), vol. 83, (no. 7_Supplement), pp. 3948, 2023-04-04. | Journal Article
 
Abstract 5005: Targeted down regulation of FGFR1 through G-quadruplex stabilization in metastatic breast cancer
Safdar, Muhammad HassanSafdar, Muhammad HassanLin, HangLin, HangDagher, SarahDagher, SarahDickerhoff, JonathanDickerhoff, JonathanYang, DanzhouYang, DanzhouWendt, Michael K. and Wendt, Michael K.
Cancer research (Chicago, Ill.), vol. 83, (no. 7_Supplement), pp. 5005, 2023-04-04. | Journal Article
 
Gas-Phase Fragmentation as a Probe of G-Quadruplex Formation.
Brundridge, Nicole MDickerhoff, JonathanYang, Danzhou and McLuckey, Scott A
Analytical chemistry, September 29, 2023. | Journal Article
2022
Decoding regulatory associations of G-quadruplex with epigenetic and transcriptomic functional components
Fang, ShuyiLiu, ShengYang, DanzhouYang, LeiHu, Chang-Deng and Wan, Jun
Frontiers in genetics, vol. 13, pp. 957023, 2022-08-25. | Journal Article
 
DNA G‑Quadruplex in Human Telomeres and Oncogene Promoters: Structures, Functions, and Small Molecule Targeting
Chen, LuyingDickerhoff, JonathanSakai, Saburo and Yang, Danzhou
Accounts of chemical research, vol. 55, (no. 18), pp. 2646, 2022-09-20. | Journal Article
 
Editorial: NAR Cancer and epigenetics and cancer.
Yang, DanzhouDickerhoff, Jonathan and Dynan, William S
NAR cancer, vol. 4, (no. 1), pp. zcac003, March 2022. | Journal Article
 
Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter.
Wang, Kai-BoLiu, YushuangLi, YipuDickerhoff, JonathanLi, JinzhuYang, Ming-HuaYang, Danzhou and Kong, Ling-Yi
Journal of the American Chemical Society, March 30, 2022. | Journal Article
 
RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes
Sun, JiazengSun, JiazengWu, GuanhuiWu, GuanhuiPastor, FlorentinPastor, FlorentinRahman, NaimurRahman, NaimurWen-Hung, WangWang, Wen-HungZhang, ZhengtaoZhang, ZhengtaoMERLE, PhilippeMERLE, PhilippeHui, LijianHui, LijianSalvetti, AnnaSalvetti, AnnaDurantel, DavidDurantel, DavidYang, DanzhouYang, DanzhouAndrisani, Ourania and Andrisani, Ourania
Gut, vol. 71, (no. 5), pp. 991-1005, May 2022. | Journal Article
 
Subnanomolar Sensitive Stable Isotopic Determination in CO2 by Tunable Infrared Laser Absorption Spectroscopy
Sakai, SaburoOtsuka, TaigaMatsuda, ShinichiSakairi, YoshiyukiUchida, RyomaSugahara, KazunoriKano, Akihiro and Yang, Danzhou
Analytical chemistry (Washington), vol. 94, (no. 17), pp. 6450, 20220503. | Journal Article
2021
Berberine Molecular Recognition of the Parallel MYC G-Quadruplex in Solution.
Dickerhoff, JonathanDickerhoff, JonathanBrundridge, NicoleBrundridge, NicoleMcLuckey, Scott AMc Luckey, Scott AYang, Danzhou and Yang, Danzhou
Journal of medicinal chemistry, October 22, 2021. | Journal Article
 
Evaluating Molecular Docking Software for Small Molecule Binding to G-Quadruplex DNA
Dickerhoff, JonathanWarnecke, Kassandra RWang, KaiboWang, KaiboDeng, NanjieDeng, NanjieYang, Danzhou and Yang, Danzhou
International Journal of Molecular Sciences, vol. 22, (no. 19), 2021. | Journal Article
 
Novel DNA Bis-Intercalator XR5944 as a Potent Anticancer Drug-Design and Mechanism of Action.
Buric, Adam JDickerhoff, Jonathan and Yang, Danzhou
Molecules (Basel, Switzerland), vol. 26, (no. 14), July 7, 2021. | Journal Article
 
RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes.
Sun, JiazengWu, GuanhuiPastor, FlorentinRahman, NaimurWang, Wen-HungZhang, ZhengtaoMerle, PhilippeHui, LijianSalvetti, AnnaDurantel, DavidYang, Danzhou and Andrisani, Ourania
Gut, May 21, 2021. | Journal Article
 
Solution Structure of Ternary Complex of Berberine Bound to a dGMP–Fill-In Vacancy G‑Quadruplex Formed in the PDGFR‑β Promoter
Wang, Kai-BoDickerhoff, Jonathan and Yang, Danzhou
Journal of the American Chemical Society, vol. 143, (no. 40), pp. 16555, 2021-10-13. | Journal Article
 
Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes.
Dickerhoff, JonathanDai, Jixun and Yang, Danzhou
Nucleic acids research, May 12, 2021. | Journal Article
2020
Combining Alchemical Transformation with a Physical Pathway to Accelerate Absolute Binding Free Energy Calculations of Charged Ligands to Enclosed Binding Sites
Cruz, JeffreyCruz, JeffreyWickstrom, LaurenWickstrom, LaurenYang, DanzhouYang, DanzhouGallicchio, EmilioGallicchio, EmilioDeng, Nanjie and Deng, Nanjie
Journal of chemical theory and computation, vol. 16, (no. 4), pp. 2813, 2020-Apr-14. | Journal Article
 
Custom DNA Microarrays Reveal Diverse Binding Preferences of Proteins and Small Molecules to Thousands of G-Quadruplexes
Ray, SreejanaTillo, DesireeBoer, Robert EAssad, NimaBarshai, MiraWu, GuanhuiOrenstein, YaronYang, DanzhouSchneekloth, Jr, John S and Vinson, Charles
ACS chemical biology, vol. 15, (no. 4), pp. 935, 2020-04-17. | Journal Article
 
Custom G4 Microarrays Reveal Selective G-Quadruplex Recognition of Small Molecule BMVC: A Large-Scale Assessment of Ligand Binding Selectivity.
Wu, GuanhuiTillo, DesireeRay, SreejanaChang, Ta-ChauSchneekloth, John SVinson, Charles and Yang, Danzhou
Molecules (Basel, Switzerland), vol. 25, (no. 15), July 30, 2020. | Journal Article
 
PDGFR-β Promoter Forms a Vacancy G-Quadruplex that Can Be Filled in by dGMP: Solution Structure and Molecular Recognition of Guanine Metabolites and Drugs
Wang, Kai-BoWang, Kai-BoDickerhoff, JonathanDickerhoff, JonathanWu, GuanhuiWu, GuanhuiYang, Danzhou and Yang, Danzhou
Journal of the American Chemical Society, vol. 142, (no. 11), pp. 5211, 2020-Mar-18. | Journal Article
2019
19F NMR Spectroscopy for the Analysis of DNA G-Quadruplex Structures Using 19F-Labeled Nucleobase
Yang, Danzhou and Lin, Clement
G-Quadruplex Nucleic Acids, vol. 2035, pp. 433, 20190101. | Journal Article
 
Abstract 1856: Targeting human telomeres by binding of epiberberine to telomeric G-quadruplex
Lin, ClementWu, GuanhuiWang, KaiboOnel, BuketSakai, Saburo and Yang, Danzhou
Cancer research (Chicago, Ill.), vol. 79, (no. 13_Supplement), pp. 1856, 2019-07-01. | Journal Article