122 Publications (Page 1 of 5)
2018
Progressive glomerular and tubular damage in sickle cell trait and sickle cell anemia mouse modelsSaraf, Santosh L⋅Saraf, Santosh L⋅Sysol, Justin R⋅Sysol, Justin R⋅Susma, Alexandru⋅Susma, Alexandru⋅Setty, Suman⋅Setty, Suman⋅Zhang, Xu⋅Zhang, Xu⋅Gudehithlu, Krishnamurthy P⋅Gudehithlu, Krishnamurthy P⋅Arruda, Jose A.L⋅Arruda, Jose A.L⋅Singh, Ashok K⋅Singh, Ashok K⋅Machado, Roberto F⋅Machado, Roberto F⋅Gordeuk, Victor R and Gordeuk, Victor RTranslational Research, vol. 197, pp. 11, July 2018.
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2017
Aberrant Caveolin-1-Mediated Smad Signaling and Proliferation Identified by Analysis of Adenine 474 Deletion Mutation (c.474delA) in Patient Fibroblasts: A New Perspective in the Mechanism of Pulmonary HypertensionMarsboom, Glenn⋅Marsboom, Glenn⋅Marsboom, Glenn⋅Chen, Zhenlong⋅Chen, Zhenlong⋅Chen, Zhenlong⋅Yuan, Yang⋅Yuan, Yang⋅Yuan, Yang⋅Zhang, Yanmin⋅Zhang, Yanmin⋅Zhang, Yanmin⋅Tiruppathi, Chinnaswamy⋅Tiruppathi, Chinnaswamy⋅Tiruppathi, Chinnaswamy⋅Loyd, James E⋅Loyd, James E⋅Loyd, James E⋅Austin, Eric D⋅Austin, Eric D⋅Austin, Eric D⋅Machado, Roberto F⋅Machado, Roberto F⋅Machado, Roberto F⋅Minshall, Richard D⋅Minshall, Richard D⋅Minshall, Richard D⋅Rehman, Jalees⋅Rehman, Jalees⋅Rehman, Jalees⋅Malik, Asrar B⋅Malik, Asrar B and Malik, Asrar BMolecular biology of the cell, pp. mbc.E16-06-0380, 2017-Mar-15.
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Association of circulating transcriptomic profiles with mortality in sickle cell disease.Desai, Ankit A.⋅Desai, Ankit A⋅Lei, Zhengdeng⋅Lei, Zhengdeng⋅Bahroos, Neil⋅Bahroos, Neil⋅Maienschein-Cline, Mark⋅Maienschein-Cline, Mark⋅Saraf, Santosh L.⋅Saraf, Santosh L⋅Zhang, Xu⋅Zhang, Xu⋅Shah, Binal N⋅Shah, Binal N.⋅Nouraie, Seyed M.⋅Nouraie, Seyed M⋅Abbasi, Taimur⋅Abbasi, Taimur⋅Patel, Amit R.⋅Patel, Amit R⋅Lang, Roberto M⋅Lang, Roberto M.⋅Lussier, Yves⋅Lussier, Yves⋅Garcia, Joe G N⋅Garcia, Joe G. N.⋅Gordeuk, Victor R.⋅Gordeuk, Victor R⋅Machado, Roberto F. and Machado, Roberto FBlood, April 3, 2017.
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Hemin Causes Lung Microvascular Endothelial Barrier Dysfunction by Necroptotic Cell DeathSingla, Sunit⋅Singla, Sunit⋅Sysol, Justin R⋅Sysol, Justin R⋅Dille, Benjamin⋅Dille, Benjamin⋅Jones, Nicole⋅Jones, Nicole⋅Chen, Jiwang⋅Chen, Jiwang⋅Machado, Roberto F and Machado, Roberto FAmerican journal of respiratory cell and molecular biology, vol. 57, (no. 3), pp. 314, 2017-09-00.
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Loss of lung WWOX expression causes neutrophilic inflammationSingla, Sunit⋅Chen, Jiwang⋅Sethuraman, Shruthi⋅Sysol, Justin R⋅Gampa, Amulya⋅Zhao, Shuangping and Machado, Roberto FAmerican journal of physiology. Lung cellular and molecular physiology, vol. 312, (no. 6), pp. L911, 2017-06-01.
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Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and Is a Therapeutic Target in Pulmonary Arterial HypertensionChen, Jiwang⋅Chen, Jiwang⋅Sysol, Justin⋅Sysol, Justin R⋅Singla, Sunit⋅Singla, Sunit⋅Zhao, Shuangping⋅Zhao, Shuangping⋅Yamamura, Aya⋅Yamamura, Aya⋅Valdez-Jasso, Daniela⋅Valdez-Jasso, Daniela⋅Abbasi, Taimur⋅Abbasi, Taimur⋅Shioura, Krystyna⋅Shioura, Krystyna M⋅Sahni, Sakshi⋅Sahni, Sakshi⋅Reddy, Vamsi⋅Reddy, Vamsi⋅Sridhar, Arvind⋅Sridhar, Arvind⋅Gao, Hui⋅Gao, Hui⋅Torres, Jaime⋅Torres, Jaime⋅Camp, Sara⋅Camp, Sara M⋅Tang, Haiyang⋅Tang, Haiyang⋅Ye, Shui Quing⋅Qing Ye, Shui⋅Comhair, Suzy⋅Comhair, Suzy⋅Dweik, Raed⋅Dweik, Raed⋅Hassoun, Paul⋅Hassoun, Paul⋅Yuan, Jason⋅Yuan, Jason X J⋅Garcia, Joe⋅Garcia, Joe G N⋅Machado, Roberto F and Machado, RobertoCirculation, vol. 135, (no. 16), pp. 1546, 2017-April-18.
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Reply to Ruan X et al: “A comment on pattern of opioid use in sickle cell disease”Han, Jin⋅Han, Jin⋅Saraf, Santosh L⋅Saraf, Santosh L⋅Machado, Roberto F⋅Machado, Roberto F⋅Gordeuk, Victor R and Gordeuk, Victor RAmerican Journal of Hematology, vol. 92, (no. 4), pp. E43, April 2017.
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2016
A genetic variation associated with plasma erythropoietin and a non-coding transcript of PRKAR1A in sickle cell diseaseZhang, Xu⋅Zhang, Xu⋅Zhang, Xu⋅Zhang, Xu⋅Shah, Binal N⋅Shah, Binal N⋅Shah, Binal N⋅Shah, Binal N⋅Zhang, Wei⋅Zhang, Wei⋅Zhang, Wei⋅Zhang, Wei⋅Saraf, Santosh L⋅Saraf, Santosh L⋅Saraf, Santosh L⋅Saraf, Santosh L⋅Miasnikova, Galina⋅Miasnikova, Galina⋅Miasnikova, Galina⋅Miasnikova, Galina⋅Sergueeva, Adelina⋅Sergueeva, Adelina⋅Sergueeva, Adelina⋅Sergueeva, Adelina⋅Ammosova, Tatiana⋅Ammosova, Tatiana⋅Ammosova, Tatiana⋅Ammosova, Tatiana⋅Niu, Xiaomei⋅Niu, Xiaomei⋅Niu, Xiaomei⋅Niu, Xiaomei⋅Nouraie, Mehdi⋅Nouraie, Mehdi⋅Nouraie, Mehdi⋅Nouraie, Mehdi⋅Nekhai, Sergei⋅Nekhai, Sergei⋅Nekhai, Sergei⋅Nekhai, Sergei⋅Castro, Oswaldo⋅Castro, Oswaldo⋅Castro, Oswaldo⋅Castro, Oswaldo⋅Gladwin, Mark T⋅Gladwin, Mark T⋅Gladwin, Mark T⋅Gladwin, Mark T⋅Prchal, Josef T⋅Prchal, Josef T⋅Prchal, Josef T⋅Prchal, Josef T⋅Garcia, Joe G N⋅Garcia, Joe G. N⋅Garcia, Joe G N⋅Garcia, Joe G. N⋅Machado, Roberto F⋅Machado, Roberto F⋅Machado, Roberto F⋅Machado, Roberto F⋅Gordeuk, Victor R⋅Gordeuk, Victor R⋅Gordeuk, Victor R and Gordeuk, Victor RHuman molecular genetics, vol. 25, (no. 20), pp. 4609, 2016-10-15.
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Annexin A11 is associated with pulmonary fibrosis in African American patients with sarcoidosisMirsaeidi, Mehdi⋅Mirsaeidi, M.⋅Mirsaeidi, Mehdi⋅Vu, Ann⋅Vu, A.⋅Vu, Ann⋅Zhang, Wei⋅Zhang, Wei⋅Zhang, W.⋅Arbieva, Z.⋅Arbieva, Zarema⋅Arbieva, Zarema⋅Zhang, Chongxu⋅Zhang, C.⋅Zhang, Chongxu⋅Abbasi, Taimur⋅Abbasi, T.⋅Abbasi, Taimur⋅Hakim, A.⋅Hakim, Anoushirvan⋅Hakim, Anoushirvan⋅Schraufnagel, D.⋅Schraufnagel, Dean⋅Schraufnagel, Dean⋅Sweiss, Nadera⋅Sweiss, Nadera⋅Sweiss, N.⋅Baughman, Robert⋅Baughman, Robert⋅Baughman, R.⋅Garcia, J.G.N.⋅Garcia, Joe G N⋅Garcia, Joe G N⋅Machado, R.F.⋅Machado, Roberto F and Machado, Roberto FSarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, vol. 33, (no. 4), pp. 418, 2016-Dec-23.
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Associations of Prolonged QTc in Sickle Cell DiseaseIndik, Julia H⋅Indik, Julia H⋅Indik, Julia H⋅Nair, Vineet⋅Nair, Vineet⋅Nair, Vineet⋅Rafikov, Ruslan⋅Rafikov, Ruslan⋅Rafikov, Ruslan⋅Nyotowidjojo, Iwan S⋅Nyotowidjojo, Iwan S⋅Nyotowidjojo, Iwan S⋅Bisla, Jaskanwal⋅Bisla, Jaskanwal⋅Bisla, Jaskanwal⋅Kansal, Mayank⋅Kansal, Mayank⋅Kansal, Mayank⋅Parikh, Devang S⋅Parikh, Devang S⋅Parikh, Devang S⋅Robinson, Melissa⋅Robinson, Melissa⋅Robinson, Melissa⋅Desai, Anand⋅Desai, Anand⋅Desai, Anand⋅Oberoi, Megha⋅Oberoi, Megha⋅Oberoi, Megha⋅Gupta, Akash⋅Gupta, Akash⋅Gupta, Akash⋅Abbasi, Taimur⋅Abbasi, Taimur⋅Abbasi, Taimur⋅Khalpey, Zain⋅Khalpey, Zain⋅Khalpey, Zain⋅Patel, Amit R⋅Patel, Amit R⋅Patel, Amit R⋅Lang, Roberto M⋅Lang, Roberto M⋅Lang, Roberto M⋅Dudley, Samuel C⋅Dudley, Samuel C⋅Dudley, Samuel C⋅Choi, Bum-Rak⋅Choi, Bum-Rak⋅Choi, Bum-Rak⋅Garcia, Joe G N⋅Garcia, Joe G N⋅Garcia, Joe G N⋅Machado, Roberto F⋅Machado, Roberto F⋅Machado, Roberto F⋅Desai, Ankit A⋅Desai, Ankit A and Desai, Ankit APloS one, vol. 11, (no. 10), pp. e0164526, 2016-00-00.
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Expression profiling elucidates a molecular gene signature for pulmonary hypertension in sarcoidosis.Singla, Sunit⋅Singla, Sunit⋅Zhou, Tong⋅Zhou, Tong⋅Javaid, Kamran⋅Javaid, Kamran⋅Abbasi, Taimur⋅Abbasi, Taimur⋅Casanova, Nancy⋅Casanova, Nancy⋅Zhang, Wei⋅Zhang, Wei⋅Ma, Shwu-Fan⋅Ma, Shwu-Fan⋅Wade, Michael S⋅Wade, Michael S⋅Noth, Imre⋅Noth, Imre⋅Sweiss, Nadera J⋅Sweiss, Nadera J⋅Garcia, Joe G N⋅Garcia, Joe G N⋅Machado, Roberto F and Machado, Roberto FPulmonary circulation, vol. 6, (no. 4), pp. 465-471, December 2016.
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Genome-Wide Analysis Identifies IL-18 and FUCA2 as Novel Genes Associated with Diastolic Function in African Americans with Sickle Cell DiseaseDuarte, J.D.⋅Duarte, Julio D⋅Duarte, Julio D⋅Desai, Ankit A⋅Desai, A.A.⋅Desai, Ankit A⋅Sysol, Justin R⋅Sysol, Justin R⋅Sysol, J.R.⋅Abbasi, Taimur⋅Abbasi, T.⋅Abbasi, Taimur⋅Patel, A.R.⋅Patel, Amit R⋅Patel, Amit R⋅Lang, Roberto M⋅Lang, R.M.⋅Lang, Roberto M⋅Gupta, Akash⋅Gupta, Akash⋅Gupta, A.⋅Garcia, Joe G N⋅Garcia, J.G.N.⋅Garcia, Joe G N⋅Gordeuk, Victor R⋅Gordeuk, V.R.⋅Gordeuk, Victor R⋅Machado, Roberto F⋅Machado, R.F. and Machado, Roberto FPloS one, vol. 11, (no. 9), pp. e0163013, 2016-00-00.
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Increased consumption and vasodilatory effect of nitrite during exerciseHon, Yuen Yi⋅Lin, Elaina E⋅Tian, Xin⋅Yang, Yang⋅Sun, He⋅Swenson, Erik R⋅Taveira-Dasilva, Angelo M⋅Gladwin, Mark T and Machado, Roberto FAmerican journal of physiology. Lung cellular and molecular physiology, vol. 310, (no. 4), pp. L364, 2016-Feb-15.
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Pathophysiology and treatment of pulmonary hypertension in sickle cell disease.Gordeuk, Victor R⋅Castro, Oswaldo L and Machado, Roberto FBlood, vol. 127, (no. 7), pp. 820-828, February 18, 2016.
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Patterns of opioid use in sickle cell diseaseHan, Jin⋅Han, Jin⋅Han, Jin⋅Saraf, Santosh L⋅Saraf, Santosh L⋅Saraf, Santosh L⋅Zhang, Xu⋅Zhang, Xu⋅Zhang, Xu⋅Gowhari, Michel⋅Gowhari, Michel⋅Gowhari, Michel⋅Molokie, Robert E⋅Molokie, Robert E⋅Molokie, Robert E⋅Hassan, Johara⋅Hassan, Joharah⋅Hassan, Joharah⋅Alhandalous, Chaher⋅Alhandalous, Chaher⋅Alhandalous, Chaher⋅Jain, Shivi⋅Jain, Shivi⋅Jain, Shivi⋅Younge, Jewel⋅Younge, Jewel⋅Younge, Jewel⋅Abbasi, Taimur⋅Abbasi, Taimur⋅Abbasi, Taimur⋅Machado, Roberto F⋅Machado, Roberto F⋅Machado, Roberto F⋅Gordeuk, Victor R⋅Gordeuk, Victor R and Gordeuk, Victor RAmerican Journal of Hematology, vol. 91, (no. 11), pp. 1106, November 2016.
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PDGF induces SphK1 expression via Egr-1 to promote pulmonary artery smooth muscle cell proliferationSysol, Justin R⋅Natarajan, Viswanathan and Machado, Roberto FAmerican journal of physiology. Cell physiology, vol. 310, (no. 11), pp. C992, 2016-06-01.
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Pulmonary hypertension associated with thalassemia syndromesFraidenburg, Dustin R and Machado, Roberto FAnnals of the New York Academy of Sciences, vol. 1368, (no. 1), pp. 139, March 2016.
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Pulmonary Vascular and Ventricular Dysfunction in the Susceptible Patient (2015 Grover Conference Series)Maron, Bradley A⋅Maron, Bradley A⋅Maron, Bradley A⋅Machado, Roberto F⋅Machado, Roberto F⋅Machado, Roberto F and Shimoda, LarissaPulmonary Circulation, vol. 6, (no. 4), pp. 426-438, Dec 2016.
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2015
Conjunctival and pulmonary hemodynamic properties in sickle cell disease subjects with and without pulmonary hypertensionKord Valeshabad, Ali⋅Kord Valeshabad, Ali⋅Wanek, Justin⋅Wanek, Justin⋅Molokie, Robert E⋅Molokie, Robert E⋅Machado, Roberto F⋅Machado, Roberto F⋅Gordeuk, Victor R⋅Gordeuk, Victor R⋅Shahidi, Mahnaz and Shahidi, MahnazClinical Case Reports, vol. 3, (no. 12), pp. 1041, December 2015.
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Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertensionTang, Haiyang⋅Goolaerts, Arnaud⋅Chen, Jiwang⋅Pellan-Randrianarison, Nadia⋅Larghero, Jérôme⋅Fraidenburg, Dustin⋅Song, Shanshan⋅Vanneaux, Valérie⋅Uzunhan, Yurdagül⋅Sysol, Justin⋅Drennan, Abigail⋅Gille, Thomas⋅Offermanns, Stefan⋅Dard, Nicolas⋅Planès, Carole⋅Ye, Richard⋅Bonini, Marcelo⋅Matthay, Michael A⋅Clerici, Christine⋅Minshall, Richard⋅Garcia, Joe⋅Machado, Roberto⋅Makino, Ayako and Yuan, JasonAmerican Journal of Physiology (Consolidated), vol. 308, (no. 1), pp. L208, 20150101.
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Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertensionTang, Haiyang⋅Tang, Haiyang⋅Chen, Jiwang⋅Chen, Jiwang⋅Fraidenburg, Dustin R⋅Fraidenburg, Dustin R⋅Song, Shanshan⋅Song, Shanshan⋅Sysol, Justin R⋅Sysol, Justin R⋅Drennan, Abigail R⋅Drennan, Abigail R⋅Offermanns, Stefan⋅Offermanns, Stefan⋅Ye, Richard D⋅Ye, Richard D⋅Bonini, Marcelo G⋅Bonini, Marcelo G⋅Minshall, Richard D⋅Minshall, Richard D⋅Garcia, Joe G N⋅Garcia, Joe G N⋅Machado, Roberto F⋅Machado, Roberto F⋅Makino, Ayako⋅Makino, Ayako⋅Yuan, Jason X J and Yuan, Jason X-JAmerican journal of physiology. Lung cellular and molecular physiology, vol. 308, (no. 2), pp. L220, 2015-Jan-15.
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Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell diseaseZhang, Xu⋅Zhang, Xu⋅Zhang, Xu⋅Zhang, Xu⋅Zhang, Wei⋅Zhang, Wei⋅Zhang, Wei⋅Zhang, Wei⋅Saraf, Santosh L⋅Saraf, Santosh⋅Saraf, Santosh⋅Saraf, Santosh L⋅Nouraie, Mehdi⋅Nouraie, Mehdi⋅Nouraie, Mehdi⋅Nouraie, Mehdi⋅Han, Jin⋅Han, Jin⋅Han, Jin⋅Han, Jin⋅Gowhari, Michel⋅Gowhari, Michel⋅Gowhari, Michel⋅Gowhari, Michel⋅Hassan, Johara⋅Hassan, Johara⋅Hassan, Johara⋅Hassan, Johara⋅Miasnikova, Galina⋅Miasnikova, Galina⋅Miasnikova, Galina⋅Miasnikova, Galina⋅Sergueeva, Adelina⋅Sergueeva, Adelina⋅Sergueeva, Adelina⋅Sergueeva, Adelina⋅Nekhai, Sergei⋅Nekhai, Sergei⋅Nekhai, Sergei⋅Nekhai, Sergei⋅Kittles, Rick⋅Kittles, Rick⋅Kittles, Rick⋅Kittles, Rick⋅Machado, Roberto⋅Machado, Roberto F⋅Machado, Roberto⋅Machado, Roberto F⋅Garcia, Joe G N⋅Garcia, Joe⋅Garcia, Joe G⋅Garcia, Joe⋅Gladwin, Mark T⋅Gladwin, Mark⋅Gladwin, Mark T⋅Gladwin, Mark⋅Steinberg, Martin⋅Steinberg, Martin⋅Steinberg, Martin H⋅Steinberg, Martin H⋅Sebastiani, Paola⋅Sebastiani, Paola⋅Sebastiani, Paola⋅Sebastiani, Paola⋅Mcclain, Donald⋅Mcclain, Donald A⋅McClain, Donald⋅Mc Clain, Donald⋅McClain, Donald A⋅Gordeuk, Victor R⋅Gordeuk, Victor⋅Gordeuk, Victor R and Gordeuk, VictorHuman Genetics, vol. 134, (no. 8), pp. 904, 20150800.
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