122 Publications (Page 1 of 5)
2018
Progressive glomerular and tubular damage in sickle cell trait and sickle cell anemia mouse models
Saraf, Santosh LSaraf, Santosh LSysol, Justin RSysol, Justin RSusma, AlexandruSusma, AlexandruSetty, SumanSetty, SumanZhang, XuZhang, XuGudehithlu, Krishnamurthy PGudehithlu, Krishnamurthy PArruda, Jose A.LArruda, Jose A.LSingh, Ashok KSingh, Ashok KMachado, Roberto FMachado, Roberto FGordeuk, Victor R and Gordeuk, Victor R
Translational Research, vol. 197, pp. 11, July 2018. | Journal Article
2017
Aberrant Caveolin-1-Mediated Smad Signaling and Proliferation Identified by Analysis of Adenine 474 Deletion Mutation (c.474delA) in Patient Fibroblasts: A New Perspective in the Mechanism of Pulmonary Hypertension
Marsboom, GlennMarsboom, GlennMarsboom, GlennChen, ZhenlongChen, ZhenlongChen, ZhenlongYuan, YangYuan, YangYuan, YangZhang, YanminZhang, YanminZhang, YanminTiruppathi, ChinnaswamyTiruppathi, ChinnaswamyTiruppathi, ChinnaswamyLoyd, James ELoyd, James ELoyd, James EAustin, Eric DAustin, Eric DAustin, Eric DMachado, Roberto FMachado, Roberto FMachado, Roberto FMinshall, Richard DMinshall, Richard DMinshall, Richard DRehman, JaleesRehman, JaleesRehman, JaleesMalik, Asrar BMalik, Asrar B and Malik, Asrar B
Molecular biology of the cell, pp. mbc.E16-06-0380, 2017-Mar-15. | Journal Article
 
Association of circulating transcriptomic profiles with mortality in sickle cell disease.
Desai, Ankit A.Desai, Ankit ALei, ZhengdengLei, ZhengdengBahroos, NeilBahroos, NeilMaienschein-Cline, MarkMaienschein-Cline, MarkSaraf, Santosh L.Saraf, Santosh LZhang, XuZhang, XuShah, Binal NShah, Binal N.Nouraie, Seyed M.Nouraie, Seyed MAbbasi, TaimurAbbasi, TaimurPatel, Amit R.Patel, Amit RLang, Roberto MLang, Roberto M.Lussier, YvesLussier, YvesGarcia, Joe G NGarcia, Joe G. N.Gordeuk, Victor R.Gordeuk, Victor RMachado, Roberto F. and Machado, Roberto F
Blood, April 3, 2017. | Journal Article
 
 
Hemin Causes Lung Microvascular Endothelial Barrier Dysfunction by Necroptotic Cell Death
Singla, SunitSingla, SunitSysol, Justin RSysol, Justin RDille, BenjaminDille, BenjaminJones, NicoleJones, NicoleChen, JiwangChen, JiwangMachado, Roberto F and Machado, Roberto F
American journal of respiratory cell and molecular biology, vol. 57, (no. 3), pp. 314, 2017-09-00. | Journal Article
 
Loss of lung WWOX expression causes neutrophilic inflammation
Singla, SunitChen, JiwangSethuraman, ShruthiSysol, Justin RGampa, AmulyaZhao, Shuangping and Machado, Roberto F
American journal of physiology. Lung cellular and molecular physiology, vol. 312, (no. 6), pp. L911, 2017-06-01. | Journal Article
 
Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and Is a Therapeutic Target in Pulmonary Arterial Hypertension
Chen, JiwangChen, JiwangSysol, JustinSysol, Justin RSingla, SunitSingla, SunitZhao, ShuangpingZhao, ShuangpingYamamura, AyaYamamura, AyaValdez-Jasso, DanielaValdez-Jasso, DanielaAbbasi, TaimurAbbasi, TaimurShioura, KrystynaShioura, Krystyna MSahni, SakshiSahni, SakshiReddy, VamsiReddy, VamsiSridhar, ArvindSridhar, ArvindGao, HuiGao, HuiTorres, JaimeTorres, JaimeCamp, SaraCamp, Sara MTang, HaiyangTang, HaiyangYe, Shui QuingQing Ye, ShuiComhair, SuzyComhair, SuzyDweik, RaedDweik, RaedHassoun, PaulHassoun, PaulYuan, JasonYuan, Jason X JGarcia, JoeGarcia, Joe G NMachado, Roberto F and Machado, Roberto
Circulation, vol. 135, (no. 16), pp. 1546, 2017-April-18. | Journal Article
 
Reply to Ruan X et al: “A comment on pattern of opioid use in sickle cell disease”
Han, JinHan, JinSaraf, Santosh LSaraf, Santosh LMachado, Roberto FMachado, Roberto FGordeuk, Victor R and Gordeuk, Victor R
American Journal of Hematology, vol. 92, (no. 4), pp. E43, April 2017. | Journal Article
2016
A genetic variation associated with plasma erythropoietin and a non-coding transcript of PRKAR1A in sickle cell disease
Zhang, XuZhang, XuZhang, XuZhang, XuShah, Binal NShah, Binal NShah, Binal NShah, Binal NZhang, WeiZhang, WeiZhang, WeiZhang, WeiSaraf, Santosh LSaraf, Santosh LSaraf, Santosh LSaraf, Santosh LMiasnikova, GalinaMiasnikova, GalinaMiasnikova, GalinaMiasnikova, GalinaSergueeva, AdelinaSergueeva, AdelinaSergueeva, AdelinaSergueeva, AdelinaAmmosova, TatianaAmmosova, TatianaAmmosova, TatianaAmmosova, TatianaNiu, XiaomeiNiu, XiaomeiNiu, XiaomeiNiu, XiaomeiNouraie, MehdiNouraie, MehdiNouraie, MehdiNouraie, MehdiNekhai, SergeiNekhai, SergeiNekhai, SergeiNekhai, SergeiCastro, OswaldoCastro, OswaldoCastro, OswaldoCastro, OswaldoGladwin, Mark TGladwin, Mark TGladwin, Mark TGladwin, Mark TPrchal, Josef TPrchal, Josef TPrchal, Josef TPrchal, Josef TGarcia, Joe G NGarcia, Joe G. NGarcia, Joe G NGarcia, Joe G. NMachado, Roberto FMachado, Roberto FMachado, Roberto FMachado, Roberto FGordeuk, Victor RGordeuk, Victor RGordeuk, Victor R and Gordeuk, Victor R
Human molecular genetics, vol. 25, (no. 20), pp. 4609, 2016-10-15. | Journal Article
 
Annexin A11 is associated with pulmonary fibrosis in African American patients with sarcoidosis
Mirsaeidi, MehdiMirsaeidi, M.Mirsaeidi, MehdiVu, AnnVu, A.Vu, AnnZhang, WeiZhang, WeiZhang, W.Arbieva, Z.Arbieva, ZaremaArbieva, ZaremaZhang, ChongxuZhang, C.Zhang, ChongxuAbbasi, TaimurAbbasi, T.Abbasi, TaimurHakim, A.Hakim, AnoushirvanHakim, AnoushirvanSchraufnagel, D.Schraufnagel, DeanSchraufnagel, DeanSweiss, NaderaSweiss, NaderaSweiss, N.Baughman, RobertBaughman, RobertBaughman, R.Garcia, J.G.N.Garcia, Joe G NGarcia, Joe G NMachado, R.F.Machado, Roberto F and Machado, Roberto F
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, vol. 33, (no. 4), pp. 418, 2016-Dec-23. | Journal Article
 
Associations of Prolonged QTc in Sickle Cell Disease
Indik, Julia HIndik, Julia HIndik, Julia HNair, VineetNair, VineetNair, VineetRafikov, RuslanRafikov, RuslanRafikov, RuslanNyotowidjojo, Iwan SNyotowidjojo, Iwan SNyotowidjojo, Iwan SBisla, JaskanwalBisla, JaskanwalBisla, JaskanwalKansal, MayankKansal, MayankKansal, MayankParikh, Devang SParikh, Devang SParikh, Devang SRobinson, MelissaRobinson, MelissaRobinson, MelissaDesai, AnandDesai, AnandDesai, AnandOberoi, MeghaOberoi, MeghaOberoi, MeghaGupta, AkashGupta, AkashGupta, AkashAbbasi, TaimurAbbasi, TaimurAbbasi, TaimurKhalpey, ZainKhalpey, ZainKhalpey, ZainPatel, Amit RPatel, Amit RPatel, Amit RLang, Roberto MLang, Roberto MLang, Roberto MDudley, Samuel CDudley, Samuel CDudley, Samuel CChoi, Bum-RakChoi, Bum-RakChoi, Bum-RakGarcia, Joe G NGarcia, Joe G NGarcia, Joe G NMachado, Roberto FMachado, Roberto FMachado, Roberto FDesai, Ankit ADesai, Ankit A and Desai, Ankit A
PloS one, vol. 11, (no. 10), pp. e0164526, 2016-00-00. | Journal Article
 
 
Expression profiling elucidates a molecular gene signature for pulmonary hypertension in sarcoidosis.
Singla, SunitZhou, TongJavaid, KamranAbbasi, TaimurCasanova, NancyZhang, WeiMa, Shwu-FanWade, Michael SNoth, ImreSweiss, Nadera JGarcia, Joe G N and Machado, Roberto F
Pulmonary circulation, vol. 6, (no. 4), pp. 465-471, December 2016. | Journal Article
 
Genome-Wide Analysis Identifies IL-18 and FUCA2 as Novel Genes Associated with Diastolic Function in African Americans with Sickle Cell Disease
Duarte, Julio DDuarte, Julio DDesai, Ankit ADesai, Ankit ASysol, Justin RSysol, Justin RAbbasi, TaimurAbbasi, TaimurPatel, Amit RPatel, Amit RLang, Roberto MLang, Roberto MGupta, AkashGupta, AkashGarcia, Joe G NGarcia, Joe G NGordeuk, Victor RGordeuk, Victor RMachado, Roberto F and Machado, Roberto F
PloS one, vol. 11, (no. 9), pp. e0163013, 2016-00-00. | Journal Article
 
Increased consumption and vasodilatory effect of nitrite during exercise
Hon, Yuen YiLin, Elaina ETian, XinYang, YangSun, HeSwenson, Erik RTaveira-Dasilva, Angelo MGladwin, Mark T and Machado, Roberto F
American journal of physiology. Lung cellular and molecular physiology, vol. 310, (no. 4), pp. L364, 2016-Feb-15. | Journal Article
 
Pathophysiology and treatment of pulmonary hypertension in sickle cell disease.
Gordeuk, Victor RCastro, Oswaldo L and Machado, Roberto F
Blood, vol. 127, (no. 7), pp. 820-828, February 18, 2016. | Journal Article
 
Patterns of opioid use in sickle cell disease
Han, JinHan, JinSaraf, Santosh LSaraf, Santosh LZhang, XuZhang, XuGowhari, MichelGowhari, MichelMolokie, Robert EMolokie, Robert EHassan, JoharahHassan, JoharaAlhandalous, ChaherAlhandalous, ChaherJain, ShiviJain, ShiviYounge, JewelYounge, JewelAbbasi, TaimurAbbasi, TaimurMachado, Roberto FMachado, Roberto FGordeuk, Victor R and Gordeuk, Victor R
American Journal of Hematology, vol. 91, (no. 11), pp. 1106, November 2016. | Journal Article
 
PDGF induces SphK1 expression via Egr-1 to promote pulmonary artery smooth muscle cell proliferation
Sysol, Justin RNatarajan, Viswanathan and Machado, Roberto F
American journal of physiology. Cell physiology, vol. 310, (no. 11), pp. C992, 2016-06-01. | Journal Article
 
Pulmonary hypertension associated with thalassemia syndromes
Fraidenburg, Dustin R and Machado, Roberto F
Annals of the New York Academy of Sciences, vol. 1368, (no. 1), pp. 139, March 2016. | Journal Article
 
Pulmonary Vascular and Ventricular Dysfunction in the Susceptible Patient (2015 Grover Conference Series)
Maron, Bradley AMaron, Bradley AMachado, Roberto F and Machado, Roberto F
Pulmonary Circulation, vol. 6, (no. 4), pp. 426-438, Dec 2016. | Journal Article
2015
Conjunctival and pulmonary hemodynamic properties in sickle cell disease subjects with and without pulmonary hypertension
Kord Valeshabad, AliKord Valeshabad, AliWanek, JustinWanek, JustinMolokie, Robert EMolokie, Robert EMachado, Roberto FMachado, Roberto FGordeuk, Victor RGordeuk, Victor RShahidi, Mahnaz and Shahidi, Mahnaz
Clinical Case Reports, vol. 3, (no. 12), pp. 1041, December 2015. | Journal Article
 
Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension
Tang, HaiyangGoolaerts, ArnaudChen, JiwangPellan-Randrianarison, NadiaLarghero, JérômeFraidenburg, DustinSong, ShanshanVanneaux, ValérieUzunhan, YurdagülSysol, JustinDrennan, AbigailGille, ThomasOffermanns, StefanDard, NicolasPlanès, CaroleYe, RichardBonini, MarceloMatthay, Michael AClerici, ChristineMinshall, RichardGarcia, JoeMachado, RobertoMakino, Ayako and Yuan, Jason
American Journal of Physiology (Consolidated), vol. 308, (no. 1), pp. L208, 20150101. | Journal Article
 
Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension
Tang, HaiyangTang, HaiyangChen, JiwangChen, JiwangFraidenburg, Dustin RFraidenburg, Dustin RSong, ShanshanSong, ShanshanSysol, Justin RSysol, Justin RDrennan, Abigail RDrennan, Abigail ROffermanns, StefanOffermanns, StefanYe, Richard DYe, Richard DBonini, Marcelo GBonini, Marcelo GMinshall, Richard DMinshall, Richard DGarcia, Joe G NGarcia, Joe G NMachado, Roberto FMachado, Roberto FMakino, AyakoMakino, AyakoYuan, Jason X J and Yuan, Jason X-J
American journal of physiology. Lung cellular and molecular physiology, vol. 308, (no. 2), pp. L220, 2015-Jan-15. | Journal Article
 
 
Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease
Zhang, XuZhang, XuZhang, XuZhang, XuZhang, WeiZhang, WeiZhang, WeiZhang, WeiSaraf, Santosh LSaraf, SantoshSaraf, SantoshSaraf, Santosh LNouraie, MehdiNouraie, MehdiNouraie, MehdiNouraie, MehdiHan, JinHan, JinHan, JinHan, JinGowhari, MichelGowhari, MichelGowhari, MichelGowhari, MichelHassan, JoharaHassan, JoharaHassan, JoharaHassan, JoharaMiasnikova, GalinaMiasnikova, GalinaMiasnikova, GalinaMiasnikova, GalinaSergueeva, AdelinaSergueeva, AdelinaSergueeva, AdelinaSergueeva, AdelinaNekhai, SergeiNekhai, SergeiNekhai, SergeiNekhai, SergeiKittles, RickKittles, RickKittles, RickKittles, RickMachado, RobertoMachado, Roberto FMachado, RobertoMachado, Roberto FGarcia, Joe G NGarcia, JoeGarcia, Joe GGarcia, JoeGladwin, Mark TGladwin, MarkGladwin, Mark TGladwin, MarkSteinberg, MartinSteinberg, MartinSteinberg, Martin HSteinberg, Martin HSebastiani, PaolaSebastiani, PaolaSebastiani, PaolaSebastiani, PaolaMcclain, DonaldMcclain, Donald AMcClain, DonaldMc Clain, DonaldMcClain, Donald AGordeuk, Victor RGordeuk, VictorGordeuk, Victor R and Gordeuk, Victor
Human Genetics, vol. 134, (no. 8), pp. 904, 20150800. | Journal Article