- Genetics, genomics and vascular biology of pulmonary hypertension and sickle cell disease
- Precision Health
- Lung health disparities
Dr. Machado's laboratory focuses on the study of pulmonary hypertension and pulmonary complications of sickle cell disease.
His laboratory also utilizes animal models of sickle cell disease and pulmonary hypertension to investigate the role of the pulmonary vascular endothelium in regulating vasomotor tone, permeability, vascular proliferation and apoptosis.
Dr. Machado’s clinical interests include pulmonary hypertension and pulmonary complications of sickle cell disease.
- Pulmonary hypertension
- Pulmonary complications of sickle cell disease