128 Publications (Page 2 of 6)
2015
Profiling of β-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39.
Kocaoglu, Ozden⋅Tsui, Ho-Ching T⋅Winkler, Malcolm E and Carlson, Erin E
Antimicrobial agents and chemotherapy, vol. 59, (no. 6), pp. 3548-3555, 2015. | Journal Article
2014
Pbp2x localizes separately from Pbp2b and other peptidoglycan synthesis proteins during later stages of cell division of Streptococcus pneumoniae D39.
Tsui, Ho-Ching T⋅Tsui, Ho‐Ching T⋅Boersma, Michael J⋅Boersma, Michael J⋅Vella, Stephen A⋅Vella, Stephen A⋅Kocaoglu, Ozden⋅Kocaoglu, Ozden⋅Kuru, Erkin⋅Kuru, Erkin⋅Peceny, Julia K⋅Peceny, Julia K⋅Carlson, Erin E⋅Carlson, Erin E⋅Van Nieuwenhze, Michael S⋅VanNieuwenhze, Michael S⋅Brun, Yves V⋅Brun, Yves V⋅Shaw, Sidney L⋅Shaw, Sidney L⋅Winkler, Malcolm E and Winkler, Malcolm E
Molecular microbiology, vol. 94, (no. 1), pp. 21-40, October 2014. | Journal Article
2013
A new structural paradigm in copper resistance in Streptococcus pneumoniae.
Fu, Yue⋅Fu, Yue⋅Fu, Yue⋅Tsui, Ho-Ching Tiffany⋅Tsui, Ho-Ching T⋅Tsui, Ho-Ching Tiffany⋅Bruce, Kevin E⋅Bruce, Kevin E⋅Bruce, Kevin E⋅Sham, Lok-To⋅Sham, Lok-To⋅Sham, Lok-To⋅Higgins, Khadine A⋅Higgins, Khadine A⋅Higgins, Khadine A⋅Lisher, John P⋅Lisher, John P⋅Lisher, John P⋅Kazmierczak, Krystyna M⋅Kazmierczak, Krystyna M⋅Kazmierczak, Krystyna M⋅Maroney, Michael J⋅Maroney, Michael J⋅Maroney, Michael J⋅Dann Iii, Charles E⋅Dann, 3rd, Charles E⋅Dann, 3rd, Charles E⋅Winkler, Malcolm E⋅Winkler, Malcolm E⋅Winkler, Malcolm E⋅Giedroc, David P⋅Giedroc, David P and Giedroc, David P
Nature chemical biology, vol. 9, (no. 3), pp. 177-83, 2013/Mar. | Journal Article
 
Involvement of FtsE ATPase and FtsX extracellular loops 1 and 2 in FtsEX-PcsB complex function in cell division of Streptococcus pneumoniae D39.
Sham, Lok-To⋅Jensen, Katelyn R⋅Bruce, Kevin E and Winkler, Malcolm E
mBio, vol. 4, (no. 4), 2013. | Journal Article
 
Requirement of essential Pbp2x and GpsB for septal ring closure in Streptococcus pneumoniae D39.
Land, Adrian D⋅Land, Adrian D⋅Tsui, Ho-Ching T⋅Tsui, Ho-Ching T⋅Kocaoglu, Ozden⋅Kocaoglu, Ozden⋅Vella, Stephen A⋅Vella, Stephen A⋅Shaw, Sidney⋅Shaw, Sidney L⋅Keen, Susan K⋅Keen, Susan K⋅Sham, Lok-To⋅Sham, Lok-To⋅Carlson, Erin E⋅Carlson, Erin E⋅Winkler, Malcolm E and Winkler, Malcolm E
Molecular microbiology, vol. 90, (no. 5), pp. 939-55, 2013/Dec. | Journal Article
2012
Involvement of WalK (VicK) phosphatase activity in setting WalR (VicR) response regulator phosphorylation level and limiting cross-talk in Streptococcus pneumoniae D39 cells
Wayne, Kyle J⋅Li, Shuo⋅Kazmierczak, Krystyna M⋅Tsui, Ho-Ching T and Winkler, Malcolm E
Molecular Microbiology, vol. 86, (no. 3), pp. 645-660, 2012. | Journal Article
 
Recent advances in pneumococcal peptidoglycan biosynthesis suggest new vaccine and antimicrobial targets
Sham, Lok-To⋅Tsui, Ho-Ching T⋅Land, Adrian D⋅Barendt, Skye M and Winkler, Malcolm E
Current Opinion in Microbiology, vol. 15, (no. 2), pp. 194-203, 2012. | Journal Article
 
Selective penicillin-binding protein imaging probes reveal substructure in bacterial cell division.
Kocaoglu, Ozden⋅Kocaoglu, Ozden⋅Calvo, Rebecca A⋅Calvo, Rebecca A⋅Sham, Lok-To⋅Sham, Lok-To⋅Cozy, Loralyn M⋅Cozy, Loralyn M⋅Lanning, Bryan R⋅Lanning, Bryan R⋅Francis, Samson⋅Francis, Samson⋅Winkler, Malcolm E⋅Winkler, Malcolm E⋅Kearns, Daniel B⋅Kearns, Daniel B⋅Carlson, Erin E and Carlson, Erin E
ACS chemical biology, vol. 7, (no. 10), pp. 1746-53, 2012/Oct/19. | Journal Article
2011
Characterization of Mutants Deficient in the L,D-Carboxypeptidase (DacB) and WalRK (VicRK) Regulon, Involved in Peptidoglycan Maturation of Streptococcus pneumoniae Serotype 2 Strain D39
Barendt, Skye M⋅Sham, Lok-To and Winkler, Malcolm E
Journal of Bacteriology, vol. 193, (no. 9), May 2011. | Journal Article
 
DegU-phosphate activates expression of the anti-sigma factor FlgM in Bacillus subtilis
Hsueh, Yi‐Huang⋅Hsueh, Yi-Huang⋅Cozy, Loralyn M⋅Cozy, Loralyn M⋅Sham, Lok‐To⋅Sham, Lok-To⋅Calvo, Rebecca A⋅Calvo, Rebecca A⋅Gutu, Alina D⋅Gutu, Alina D⋅Winkler, Malcolm E⋅Winkler, Malcolm E⋅Kearns, Daniel B and Kearns, Daniel B
Molecular Microbiology, vol. 81, (no. 4), pp. 1092-1108, 2011. | Journal Article
 
Dynamic distribution of the SecA and SecY translocase subunits and septal localization of the HtrA surface chaperone/protease during Streptococcus pneumoniae D39 cell division.
Tsui, Ho-Ching T⋅Keen, Susan K⋅Sham, Lok-To⋅Wayne, Kyle J and Winkler, Malcolm E
mBio, vol. 2, (no. 5), 2011. | Journal Article
 
Essential PcsB putative peptidoglycan hydrolase interacts with the essential FtsXspncell division protein in Streptococcus pneumoniae D39
Sham, Lok-To⋅Barendt, Skye⋅Kopecky, Kimberly and Winkler, Malcolm
Proceedings of the National Academy of Sciences of the United States of America, vol. 108, (no. 45), pp. 18212, 20111108. | Journal Article
 
Essential PcsB putative peptidoglycan hydrolase interacts with the essential FtsXSpn cell division protein in Streptococcus pneumoniae D39.
Sham, Lok-To⋅Barendt, Skye M⋅Kopecky, Kimberly E and Winkler, Malcolm E
Proceedings of the National Academy of Sciences of the United States of America, vol. 108, (no. 45), pp. E1061-9, 2011/Nov/8. | Journal Article
 
Essential PcsB putative peptidoglycan hydrolase interacts with the essential FtsX^sub Spn^ cell division protein in Streptococcus pneumoniae D39
Sham, Lok-To⋅Barendt, Skye M⋅Kopecky, Kimberly E and Winkler, Malcolm E
Proceedings of the National Academy of Sciences of the United States of America, vol. 108, (no. 45), Nov 8, 2011. | Journal Article
 
Interplay between manganese and zinc homeostasis in the human pathogen Streptococcus pneumoniae
Jacobsen, Faith E⋅Kazmierczak, Krystyna M⋅Lisher, John P⋅Winkler, Malcolm E and Giedroc, David P
Metallomics, vol. 3, (no. 1), pp. 38-41, 2011. | Journal Article
 
Phenotypic Landscape of a Bacterial Cell
Nichols, Robert J⋅Sen, Saunak⋅Choo, Yoe J⋅Beltrao, Pedro⋅Zietek, Matylda⋅Chaba, Rachna⋅Lee, Sueyoung⋅Kazmierczak, Krystyna M⋅Lee, Karis J⋅Wong*, Angela⋅Wong, Angela⋅Shales*, Michael⋅Shales, Michael⋅Lovett, Susan T⋅Winkler, Malcolm E⋅Krogan, Nevan⋅Typas*, Athanasios⋅Typas, Athanasios and Gross, Carol A
Cell, vol. 144, (no. 1), pp. 143-156, 2011. | Journal Article
 
The Putative Hydrolase YycJ (WalJ) Affects the Coordination of Cell Division with DNA Replication in Bacillus subtilis and May Play a Conserved Role in Cell Wall Metabolism
Biller, Steven J⋅Biller, Steven⋅Wayne, Kyle⋅Wayne, Kyle J⋅Winkler, Malcolm E⋅Winkler, Malcolm⋅Burkholder, William F and Burkholder, William
Journal of Bacteriology, vol. 193, (no. 4), Feb 2011. | Journal Article
 
The Requirement for Pneumococcal MreC and MreD Is Relieved by Inactivation of the Gene Encoding PBP1a
Land, Adrian D and Winkler, Malcolm E
Journal of Bacteriology, vol. 193, (no. 16), Aug 2011. | Journal Article
2010
Identification and characterization of noncoding small RNAs in Streptococcus pneumoniae serotype 2 strain D39.
Tsui, Ho-Ching T⋅Mukherjee, Dhriti⋅Ray, Valerie A⋅Sham, Lok-To⋅Feig, Andrew L and Winkler, Malcolm E
Journal of bacteriology, vol. 192, (no. 1), pp. 264-79, 2010/Jan. | Journal Article
 
Instability of ackA (Acetate Kinase) Mutations and Their Effects on Acetyl Phosphate and ATP Amounts in Streptococcus pneumoniae D39
Ramos-Montanez, Smirla⋅Kazmierczak, Krystyna M⋅Hentchel, Kristy L and Winkler, Malcolm E
Journal of Bacteriology, vol. 192, (no. 24), pp. 6390-6400, 2010. | Journal Article
 
Kinetic characterization of the WalRKSpn (VicRK) two-component system of Streptococcus pneumoniae: dependence of WalKSpn (VicK) phosphatase activity on its PAS domain.
Gutu, Alina D⋅Wayne, Kyle J⋅Sham, Lok-To and Winkler, Malcolm E
Journal of bacteriology, vol. 192, (no. 9), pp. 2346-58, 2010/May. | Journal Article
 
Kinetic Characterization of the WalRK^sub Spn^ (VicRK) Two-Component System of Streptococcus pneumoniae: Dependence of WalK^sub Spn^ (VicK) Phosphatase Activity on Its PAS Domain
Gutu, Alina D⋅Wayne, Kyle J⋅Sham, Lok-To and Winkler, Malcolm E
Journal of Bacteriology, vol. 192, (no. 9), May 2010. | Journal Article
 
Localization and cellular amounts of the WalRKJ (VicRKX) two-component regulatory system proteins in serotype 2 Streptococcus pneumoniae.
Wayne, Kyle J⋅Sham, Lok-To⋅Tsui, Ho-Ching T⋅Gutu, Alina D⋅Barendt, Skye M⋅Keen, Susan K and Winkler, Malcolm E
Journal of bacteriology, vol. 192, (no. 17), pp. 4388-94, 2010/Sep. | Journal Article
 
On the Structure, Function and Metalloregulatory Properties of the Zinc-Activated Repressor Streptococcus Pneumoniae AdcR
Guerra, Alfredo J⋅Guerra, Alfredo J⋅Reyes-Caballero, Hermes⋅Reyes-Caballero, Hermes⋅Jacobsen, Faith E⋅Jacobsen, Faith E⋅Koppolu, Uma Mahendra Kumar⋅Koppolu, Uma Mahendra Kumar⋅Scott, Robert A⋅Scott, Robert A⋅Kazmierczak, Krystyna M⋅Kazmierczak, Krystyna M⋅Winkler, Malcolm E⋅Winkler, Malcolm E⋅Giedroc, David P and Giedroc, David P
Biophysical Journal, vol. 98, (no. 3), pp. 73, 2010-01-00. | Journal Article
 
The Metalloregulatory Zinc Site in Streptococcus pneumoniae AdcR, a Zinc-activated MarR Family Repressor
Reyes-Caballero, Hermes⋅Guerra, Alfredo J⋅Jacobsen, Faith E⋅Kazmierczak, Krystyna M⋅Cowart, Darin⋅Koppolu, Uma M⋅Scott, Robert A⋅Winkler, Malcolm E and Giedroc, David P
Journal of Molecular Biology, vol. 403, (no. 2), pp. 197-216, 2010. | Journal Article